GAS1 (growth arrest specific 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 2619 |
| Gene name | Growth arrest specific 1 |
| Gene symbol | GAS1 |
| Synonyms (NCBI Gene) |
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| Chromosome | 9 |
| Chromosome location | 9q21.33 |
| Summary | Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P54826 | ||||||||||
| Protein name | Growth arrest-specific protein 1 (GAS-1) | ||||||||||
| Protein function | Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells. Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity). {ECO:0000250|UniProtKB:Q01721, ECO:0000269|PubM | ||||||||||
| PDB | 7RHQ | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 345 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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