PHF19 (PHD finger protein 19)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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26147 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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PHD finger protein 19 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PHF19 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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MTF2L1, PCL3, TDRD19B |
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Chromosome
Chromosome number
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9 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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9q33.2 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q5T6S3 | ||||||||||||||||||||
| Protein name | PHD finger protein 19 (Polycomb-like protein 3) (hPCL3) | ||||||||||||||||||||
| Protein function | Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity (PubMed:15563832, PubMed:18691976, PubMed:23104054, PubMed:2316 | ||||||||||||||||||||
| PDB | 2E5Q , 4BD3 , 6NQ3 , 6WAU | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Isoform 1 is expressed in thymus, heart, lung and kidney. Isoform 2 is predominantly expressed in placenta, skeletal muscle and kidney, whereas isoform 1 is predominantly expressed in liver and peripheral blood leukocytes. Overexpresse | ||||||||||||||||||||
| Sequence |
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| Sequence length | 580 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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