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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8NC51 |
| Protein name |
SERPINE1 mRNA-binding protein 1 (PAI1 RNA-binding protein 1) (PAI-RBP1) (Plasminogen activator inhibitor 1 RNA-binding protein) |
| Protein function |
Ribosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (PubMed:36691768). Acts via its association with EEF2/eEF2 factor, seque |
| PDB |
4V6X
, 6Z6M
, 6Z6N
, 8K2C
, 8UKB
, 8XSX
, 8XSY
, 8XSZ
, 8Y0W
, 8Y0X
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| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
| PF16174 |
IHABP4_N |
5 → 152 |
Intracellular hyaluronan-binding protein 4 N-terminal |
Family |
| PF04774 |
HABP4_PAI-RBP1 |
189 → 313 |
Hyaluronan / mRNA binding family |
Family |
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| Tissue specificity |
TISSUE SPECIFICITY: Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. {ECO:0000269|PubMed:12505151}. |
| Sequence |
|
| Sequence length |
408 |
| Interactions |
View interactions |