FGFR1OP2 (FGFR1 oncogene partner 2)

Gene

• Entrez ID: 26127
• Gene name: FGFR1 oncogene partner 2
• Gene symbol: FGFR1OP2
• Synonyms (NCBI Gene): HSPC123-like, WIT3.0
• Chromosome: 12
• Chromosome location: 12p11.23

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020087	hsa-miR-361-5p	Sequencing	20371350
MIRT712710	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT712709	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT712708	hsa-miR-6859-3p	HITS-CLIP	19536157
MIRT712707	hsa-miR-711	HITS-CLIP	19536157
MIRT642711	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT642710	hsa-miR-4301	HITS-CLIP	23824327
MIRT642709	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT642708	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT642707	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT642706	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT642705	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT642704	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT642703	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT642702	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT642701	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT642700	hsa-miR-4284	HITS-CLIP	23824327
MIRT642699	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT633282	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT633281	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT633280	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT633279	hsa-miR-5695	HITS-CLIP	23824327
MIRT633278	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT633277	hsa-miR-6131	HITS-CLIP	23824327
MIRT633276	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT633275	hsa-miR-1200	HITS-CLIP	23824327
MIRT633274	hsa-miR-515-5p	HITS-CLIP	23824327
MIRT633273	hsa-miR-519e-5p	HITS-CLIP	23824327
MIRT633272	hsa-miR-548s	HITS-CLIP	23824327
MIRT633271	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT633270	hsa-miR-588	HITS-CLIP	23824327
MIRT633269	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT633268	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT633267	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT712710	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT712709	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT712708	hsa-miR-6859-3p	HITS-CLIP	19536157
MIRT712707	hsa-miR-711	HITS-CLIP	19536157
MIRT642711	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT642710	hsa-miR-4301	HITS-CLIP	23824327
MIRT642709	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT642708	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT642707	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT642706	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT642705	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT642704	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT642703	hsa-miR-532-3p	HITS-CLIP	23824327
MIRT642702	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT642701	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT642700	hsa-miR-4284	HITS-CLIP	23824327
MIRT642699	hsa-miR-3156-3p	HITS-CLIP	23824327
MIRT633282	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT633281	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT633280	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT633279	hsa-miR-5695	HITS-CLIP	23824327
MIRT633278	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT633277	hsa-miR-6131	HITS-CLIP	23824327
MIRT633276	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT633275	hsa-miR-1200	HITS-CLIP	23824327
MIRT633274	hsa-miR-515-5p	HITS-CLIP	23824327
MIRT633273	hsa-miR-519e-5p	HITS-CLIP	23824327
MIRT633272	hsa-miR-548s	HITS-CLIP	23824327
MIRT633271	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT633270	hsa-miR-588	HITS-CLIP	23824327
MIRT633269	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT633268	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT633267	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT996000	hsa-miR-103b	CLIP-seq
MIRT996001	hsa-miR-1208	CLIP-seq
MIRT996002	hsa-miR-129-5p	CLIP-seq
MIRT996003	hsa-miR-1298	CLIP-seq
MIRT996004	hsa-miR-142-5p	CLIP-seq
MIRT996005	hsa-miR-1973	CLIP-seq
MIRT996006	hsa-miR-199a-3p	CLIP-seq
MIRT996007	hsa-miR-199b-3p	CLIP-seq
MIRT996008	hsa-miR-3129-5p	CLIP-seq
MIRT996009	hsa-miR-3651	CLIP-seq
MIRT996010	hsa-miR-3919	CLIP-seq
MIRT996011	hsa-miR-3940-3p	CLIP-seq
MIRT996012	hsa-miR-3973	CLIP-seq
MIRT996013	hsa-miR-4452	CLIP-seq
MIRT996014	hsa-miR-4652-3p	CLIP-seq
MIRT996015	hsa-miR-4699-3p	CLIP-seq
MIRT996016	hsa-miR-4797-5p	CLIP-seq
MIRT996017	hsa-miR-495	CLIP-seq
MIRT996018	hsa-miR-511	CLIP-seq
MIRT996019	hsa-miR-548a-5p	CLIP-seq
MIRT996020	hsa-miR-548ab	CLIP-seq
MIRT996021	hsa-miR-548ak	CLIP-seq
MIRT996022	hsa-miR-548b-5p	CLIP-seq
MIRT996023	hsa-miR-548c-5p	CLIP-seq
MIRT996024	hsa-miR-548d-5p	CLIP-seq
MIRT996025	hsa-miR-548h	CLIP-seq
MIRT996026	hsa-miR-548i	CLIP-seq
MIRT996027	hsa-miR-548j	CLIP-seq
MIRT996028	hsa-miR-548w	CLIP-seq
MIRT996029	hsa-miR-548y	CLIP-seq
MIRT996030	hsa-miR-559	CLIP-seq
MIRT996031	hsa-miR-570	CLIP-seq
MIRT996032	hsa-miR-586	CLIP-seq
MIRT996033	hsa-miR-591	CLIP-seq
MIRT996034	hsa-miR-664	CLIP-seq
MIRT996035	hsa-miR-936	CLIP-seq
MIRT996001	hsa-miR-1208	CLIP-seq
MIRT996036	hsa-miR-129-3p	CLIP-seq
MIRT996037	hsa-miR-1305	CLIP-seq
MIRT996006	hsa-miR-199a-3p	CLIP-seq
MIRT996007	hsa-miR-199b-3p	CLIP-seq
MIRT996008	hsa-miR-3129-5p	CLIP-seq
MIRT996038	hsa-miR-3163	CLIP-seq
MIRT996039	hsa-miR-340	CLIP-seq
MIRT996040	hsa-miR-34b	CLIP-seq
MIRT996041	hsa-miR-34c-3p	CLIP-seq
MIRT996042	hsa-miR-3671	CLIP-seq
MIRT996043	hsa-miR-409-3p	CLIP-seq
MIRT996044	hsa-miR-410	CLIP-seq
MIRT996045	hsa-miR-4422	CLIP-seq
MIRT996046	hsa-miR-4464	CLIP-seq
MIRT996047	hsa-miR-4640-5p	CLIP-seq
MIRT996048	hsa-miR-4687-5p	CLIP-seq
MIRT996049	hsa-miR-4705	CLIP-seq
MIRT996050	hsa-miR-4726-5p	CLIP-seq
MIRT996051	hsa-miR-4729	CLIP-seq
MIRT996052	hsa-miR-4748	CLIP-seq
MIRT996031	hsa-miR-570	CLIP-seq
MIRT996035	hsa-miR-936	CLIP-seq
MIRT996003	hsa-miR-1298	CLIP-seq
MIRT2229428	hsa-miR-197	CLIP-seq
MIRT996005	hsa-miR-1973	CLIP-seq
MIRT2229429	hsa-miR-203	CLIP-seq
MIRT2229430	hsa-miR-24	CLIP-seq
MIRT2229431	hsa-miR-337-3p	CLIP-seq
MIRT996040	hsa-miR-34b	CLIP-seq
MIRT2229432	hsa-miR-3653	CLIP-seq
MIRT2229433	hsa-miR-374c	CLIP-seq
MIRT996012	hsa-miR-3973	CLIP-seq
MIRT2229434	hsa-miR-4328	CLIP-seq
MIRT2229435	hsa-miR-4528	CLIP-seq
MIRT2229436	hsa-miR-4666-3p	CLIP-seq
MIRT996015	hsa-miR-4699-3p	CLIP-seq
MIRT996049	hsa-miR-4705	CLIP-seq
MIRT2229437	hsa-miR-4803	CLIP-seq
MIRT996017	hsa-miR-495	CLIP-seq
MIRT996019	hsa-miR-548a-5p	CLIP-seq
MIRT996020	hsa-miR-548ab	CLIP-seq
MIRT996021	hsa-miR-548ak	CLIP-seq
MIRT996022	hsa-miR-548b-5p	CLIP-seq
MIRT996023	hsa-miR-548c-5p	CLIP-seq
MIRT996024	hsa-miR-548d-5p	CLIP-seq
MIRT996025	hsa-miR-548h	CLIP-seq
MIRT996026	hsa-miR-548i	CLIP-seq
MIRT996027	hsa-miR-548j	CLIP-seq
MIRT996028	hsa-miR-548w	CLIP-seq
MIRT996029	hsa-miR-548y	CLIP-seq
MIRT996030	hsa-miR-559	CLIP-seq
MIRT996033	hsa-miR-591	CLIP-seq
MIRT2229438	hsa-miR-655	CLIP-seq
MIRT996034	hsa-miR-664	CLIP-seq
MIRT2387986	hsa-miR-4775	CLIP-seq
MIRT2387987	hsa-miR-491-3p	CLIP-seq
MIRT996032	hsa-miR-586	CLIP-seq
MIRT2387988	hsa-miR-590-3p	CLIP-seq
MIRT2449682	hsa-miR-4282	CLIP-seq
MIRT2449683	hsa-miR-4719	CLIP-seq
MIRT2449684	hsa-miR-513b	CLIP-seq
MIRT2533280	hsa-miR-1207-3p	CLIP-seq
MIRT996037	hsa-miR-1305	CLIP-seq
MIRT2533281	hsa-miR-188-5p	CLIP-seq
MIRT2229428	hsa-miR-197	CLIP-seq
MIRT2533282	hsa-miR-204	CLIP-seq
MIRT2533283	hsa-miR-211	CLIP-seq
MIRT2533284	hsa-miR-3117-5p	CLIP-seq
MIRT2533285	hsa-miR-3126-3p	CLIP-seq
MIRT2533286	hsa-miR-3145-5p	CLIP-seq
MIRT2533287	hsa-miR-323-5p	CLIP-seq
MIRT2533288	hsa-miR-3647-3p	CLIP-seq
MIRT2229432	hsa-miR-3653	CLIP-seq
MIRT2533289	hsa-miR-3658	CLIP-seq
MIRT2533290	hsa-miR-3686	CLIP-seq
MIRT2533291	hsa-miR-3688-5p	CLIP-seq
MIRT2533292	hsa-miR-371-5p	CLIP-seq
MIRT2533293	hsa-miR-371b-5p	CLIP-seq
MIRT2229433	hsa-miR-374c	CLIP-seq
MIRT2533294	hsa-miR-4272	CLIP-seq
MIRT2449682	hsa-miR-4282	CLIP-seq
MIRT2533295	hsa-miR-4286	CLIP-seq
MIRT2533296	hsa-miR-4299	CLIP-seq
MIRT996045	hsa-miR-4422	CLIP-seq
MIRT2533297	hsa-miR-4456	CLIP-seq
MIRT996046	hsa-miR-4464	CLIP-seq
MIRT2533298	hsa-miR-4470	CLIP-seq
MIRT2533299	hsa-miR-4534	CLIP-seq
MIRT2533300	hsa-miR-4633-3p	CLIP-seq
MIRT2533301	hsa-miR-4640-3p	CLIP-seq
MIRT2533302	hsa-miR-4646-5p	CLIP-seq
MIRT996014	hsa-miR-4652-3p	CLIP-seq
MIRT2229436	hsa-miR-4666-3p	CLIP-seq
MIRT996015	hsa-miR-4699-3p	CLIP-seq
MIRT996049	hsa-miR-4705	CLIP-seq
MIRT2449683	hsa-miR-4719	CLIP-seq
MIRT2533303	hsa-miR-4742-3p	CLIP-seq
MIRT996052	hsa-miR-4748	CLIP-seq
MIRT2533304	hsa-miR-4766-5p	CLIP-seq
MIRT2387986	hsa-miR-4775	CLIP-seq
MIRT2533305	hsa-miR-4778-3p	CLIP-seq
MIRT2229437	hsa-miR-4803	CLIP-seq
MIRT2533306	hsa-miR-488	CLIP-seq
MIRT2387987	hsa-miR-491-3p	CLIP-seq
MIRT2533307	hsa-miR-508-5p	CLIP-seq
MIRT2449684	hsa-miR-513b	CLIP-seq
MIRT2533308	hsa-miR-513c	CLIP-seq
MIRT2533309	hsa-miR-514b-5p	CLIP-seq
MIRT2533310	hsa-miR-548ac	CLIP-seq
MIRT2533311	hsa-miR-548ae	CLIP-seq
MIRT2533312	hsa-miR-548aj	CLIP-seq
MIRT2533313	hsa-miR-548am	CLIP-seq
MIRT2533314	hsa-miR-548d-3p	CLIP-seq
MIRT2533315	hsa-miR-548q	CLIP-seq
MIRT2533316	hsa-miR-548x	CLIP-seq
MIRT2533317	hsa-miR-548z	CLIP-seq
MIRT996032	hsa-miR-586	CLIP-seq
MIRT2387988	hsa-miR-590-3p	CLIP-seq
MIRT2229438	hsa-miR-655	CLIP-seq
MIRT2533318	hsa-miR-876-3p	CLIP-seq
MIRT2533280	hsa-miR-1207-3p	CLIP-seq
MIRT2680981	hsa-miR-1224-5p	CLIP-seq
MIRT2680982	hsa-miR-154	CLIP-seq
MIRT2533281	hsa-miR-188-5p	CLIP-seq
MIRT2533282	hsa-miR-204	CLIP-seq
MIRT2533283	hsa-miR-211	CLIP-seq
MIRT2533286	hsa-miR-3145-5p	CLIP-seq
MIRT2229432	hsa-miR-3653	CLIP-seq
MIRT2533289	hsa-miR-3658	CLIP-seq
MIRT2680983	hsa-miR-3665	CLIP-seq
MIRT2533291	hsa-miR-3688-5p	CLIP-seq
MIRT2533292	hsa-miR-371-5p	CLIP-seq
MIRT2533293	hsa-miR-371b-5p	CLIP-seq
MIRT2229433	hsa-miR-374c	CLIP-seq
MIRT2449682	hsa-miR-4282	CLIP-seq
MIRT2533295	hsa-miR-4286	CLIP-seq
MIRT2533298	hsa-miR-4470	CLIP-seq
MIRT2533301	hsa-miR-4640-3p	CLIP-seq
MIRT2229436	hsa-miR-4666-3p	CLIP-seq
MIRT2449683	hsa-miR-4719	CLIP-seq
MIRT2680984	hsa-miR-4751	CLIP-seq
MIRT2533304	hsa-miR-4766-5p	CLIP-seq
MIRT2387986	hsa-miR-4775	CLIP-seq
MIRT2533305	hsa-miR-4778-3p	CLIP-seq
MIRT2533306	hsa-miR-488	CLIP-seq
MIRT2387987	hsa-miR-491-3p	CLIP-seq
MIRT2533307	hsa-miR-508-5p	CLIP-seq
MIRT2449684	hsa-miR-513b	CLIP-seq
MIRT2533308	hsa-miR-513c	CLIP-seq
MIRT2533309	hsa-miR-514b-5p	CLIP-seq
MIRT2680985	hsa-miR-548c-3p	CLIP-seq
MIRT996032	hsa-miR-586	CLIP-seq
MIRT2387988	hsa-miR-590-3p	CLIP-seq
MIRT2229438	hsa-miR-655	CLIP-seq
MIRT2680986	hsa-miR-657	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0009611	Process	Response to wounding	IBA
GO:0042060	Process	Wound healing	IEA
GO:0042802	Function	Identical protein binding	IEA

Other IDs

• MIM: 608858
• HGNC: 23098
• e!Ensembl: ENSG00000111790

Protein

• UniProt ID: Q9NVK5
• Protein name: FGFR1 oncogene partner 2
• Protein function: May be involved in wound healing pathway.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05769	SIKE	2 → 142	SIKE family	Family
  PF05769	SIKE	146 → 221	SIKE family	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in bone marrow, spleen and thymus.
• Sequence:

  MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHR
  PRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDP
  GIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQIT
  EMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLS
  ALVTNSDLSLRKS

• Sequence length: 253

Pathways

Reactome:

Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Cervical cancer	Uncertain significance	rs1939131460	RCV005932532

Associations from Text Mining
Disease Name	Relationship Type	References
Atrophy	Associate	22880093
Jaw Edentulous	Associate	21283824, 22880093
Lymphoma B Cell Marginal Zone	Associate	21283824
Neoplasm Residual	Associate	22880093
Neoplasms	Associate	24045656