Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	26122
Gene name Gene Name - the full gene name approved by the HGNC.	Enhancer of polycomb 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	EPC2
Synonyms (NCBI Gene) Gene synonyms aliases	EPC-LIKE
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q23.1

Show/Hide all(159)

miRTarBase ID	miRNA	Experiments	Reference
MIRT085668	hsa-miR-194-5p	PAR-CLIP	21572407
MIRT085676	hsa-miR-5692a	PAR-CLIP	21572407
MIRT085671	hsa-miR-802	PAR-CLIP	21572407
MIRT085677	hsa-miR-5692b	PAR-CLIP	21572407
MIRT085675	hsa-miR-5692c	PAR-CLIP	21572407
MIRT558083	hsa-miR-4272	PAR-CLIP	21572407
MIRT558082	hsa-miR-5697	PAR-CLIP	21572407
MIRT447801	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT447800	hsa-miR-3662	PAR-CLIP	22100165
MIRT203708	hsa-miR-944	PAR-CLIP	22100165
MIRT447799	hsa-miR-499a-3p	PAR-CLIP	22100165
MIRT447798	hsa-miR-499b-3p	PAR-CLIP	22100165
MIRT447797	hsa-miR-4635	PAR-CLIP	22100165
MIRT447796	hsa-miR-183-3p	PAR-CLIP	22100165
MIRT447795	hsa-miR-4452	PAR-CLIP	22100165
MIRT085668	hsa-miR-194-5p	PAR-CLIP	21572407
MIRT085676	hsa-miR-5692a	PAR-CLIP	21572407
MIRT085671	hsa-miR-802	PAR-CLIP	21572407
MIRT085677	hsa-miR-5692b	PAR-CLIP	21572407
MIRT085675	hsa-miR-5692c	PAR-CLIP	21572407
MIRT558083	hsa-miR-4272	PAR-CLIP	21572407
MIRT558082	hsa-miR-5697	PAR-CLIP	21572407
MIRT447801	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT447800	hsa-miR-3662	PAR-CLIP	22100165
MIRT203708	hsa-miR-944	PAR-CLIP	22100165
MIRT447799	hsa-miR-499a-3p	PAR-CLIP	22100165
MIRT447798	hsa-miR-499b-3p	PAR-CLIP	22100165
MIRT447797	hsa-miR-4635	PAR-CLIP	22100165
MIRT447796	hsa-miR-183-3p	PAR-CLIP	22100165
MIRT447795	hsa-miR-4452	PAR-CLIP	22100165
MIRT965941	hsa-miR-1207-3p	CLIP-seq
MIRT965942	hsa-miR-1245	CLIP-seq
MIRT965943	hsa-miR-1279	CLIP-seq
MIRT965944	hsa-miR-1286	CLIP-seq
MIRT965945	hsa-miR-1290	CLIP-seq
MIRT965946	hsa-miR-1297	CLIP-seq
MIRT965947	hsa-miR-130a	CLIP-seq
MIRT965948	hsa-miR-130b	CLIP-seq
MIRT965949	hsa-miR-186	CLIP-seq
MIRT965950	hsa-miR-196a	CLIP-seq
MIRT965951	hsa-miR-196b	CLIP-seq
MIRT965952	hsa-miR-19a	CLIP-seq
MIRT965953	hsa-miR-19b	CLIP-seq
MIRT965954	hsa-miR-224	CLIP-seq
MIRT965955	hsa-miR-26a	CLIP-seq
MIRT965956	hsa-miR-26b	CLIP-seq
MIRT965957	hsa-miR-301a	CLIP-seq
MIRT965958	hsa-miR-301b	CLIP-seq
MIRT965959	hsa-miR-3065-3p	CLIP-seq
MIRT965960	hsa-miR-30a	CLIP-seq
MIRT965961	hsa-miR-30b	CLIP-seq
MIRT965962	hsa-miR-30c	CLIP-seq
MIRT965963	hsa-miR-30d	CLIP-seq
MIRT965964	hsa-miR-30e	CLIP-seq
MIRT965965	hsa-miR-3133	CLIP-seq
MIRT965966	hsa-miR-3152-5p	CLIP-seq
MIRT965967	hsa-miR-3163	CLIP-seq
MIRT965968	hsa-miR-3167	CLIP-seq
MIRT965969	hsa-miR-33a	CLIP-seq
MIRT965970	hsa-miR-33b	CLIP-seq
MIRT965971	hsa-miR-3591-3p	CLIP-seq
MIRT965972	hsa-miR-3614-3p	CLIP-seq
MIRT965973	hsa-miR-3659	CLIP-seq
MIRT965974	hsa-miR-3664-5p	CLIP-seq
MIRT965975	hsa-miR-3666	CLIP-seq
MIRT965976	hsa-miR-3676	CLIP-seq
MIRT965977	hsa-miR-3942-3p	CLIP-seq
MIRT965978	hsa-miR-4282	CLIP-seq
MIRT965979	hsa-miR-4295	CLIP-seq
MIRT965980	hsa-miR-4312	CLIP-seq
MIRT965981	hsa-miR-4328	CLIP-seq
MIRT965982	hsa-miR-433	CLIP-seq
MIRT965983	hsa-miR-4422	CLIP-seq
MIRT965984	hsa-miR-4423-5p	CLIP-seq
MIRT965985	hsa-miR-4446-5p	CLIP-seq
MIRT965986	hsa-miR-4465	CLIP-seq
MIRT965987	hsa-miR-4470	CLIP-seq
MIRT965988	hsa-miR-4494	CLIP-seq
MIRT965989	hsa-miR-4495	CLIP-seq
MIRT965990	hsa-miR-450b-5p	CLIP-seq
MIRT965991	hsa-miR-4517	CLIP-seq
MIRT965992	hsa-miR-454	CLIP-seq
MIRT965993	hsa-miR-4661-3p	CLIP-seq
MIRT965994	hsa-miR-4668-3p	CLIP-seq
MIRT965995	hsa-miR-4676-5p	CLIP-seq
MIRT965996	hsa-miR-4677-3p	CLIP-seq
MIRT965997	hsa-miR-4679	CLIP-seq
MIRT965998	hsa-miR-4684-3p	CLIP-seq
MIRT965999	hsa-miR-4698	CLIP-seq
MIRT966000	hsa-miR-4704-5p	CLIP-seq
MIRT966001	hsa-miR-4722-5p	CLIP-seq
MIRT966002	hsa-miR-4755-5p	CLIP-seq
MIRT966003	hsa-miR-4766-5p	CLIP-seq
MIRT966004	hsa-miR-4774-3p	CLIP-seq
MIRT966005	hsa-miR-4797-5p	CLIP-seq
MIRT966006	hsa-miR-494	CLIP-seq
MIRT966007	hsa-miR-495	CLIP-seq
MIRT966008	hsa-miR-499a-5p	CLIP-seq
MIRT966009	hsa-miR-507	CLIP-seq
MIRT966010	hsa-miR-5096	CLIP-seq
MIRT966011	hsa-miR-518a-5p	CLIP-seq
MIRT966012	hsa-miR-519a	CLIP-seq
MIRT966013	hsa-miR-519b-3p	CLIP-seq
MIRT966014	hsa-miR-519c-3p	CLIP-seq
MIRT966015	hsa-miR-520d-5p	CLIP-seq
MIRT966016	hsa-miR-524-5p	CLIP-seq
MIRT966017	hsa-miR-527	CLIP-seq
MIRT966018	hsa-miR-543	CLIP-seq
MIRT966019	hsa-miR-557	CLIP-seq
MIRT966020	hsa-miR-575	CLIP-seq
MIRT966021	hsa-miR-582-5p	CLIP-seq
MIRT966022	hsa-miR-590-3p	CLIP-seq
MIRT966023	hsa-miR-600	CLIP-seq
MIRT966024	hsa-miR-624	CLIP-seq
MIRT966025	hsa-miR-640	CLIP-seq
MIRT966026	hsa-miR-670	CLIP-seq
MIRT966027	hsa-miR-759	CLIP-seq
MIRT966028	hsa-miR-876-5p	CLIP-seq
MIRT965943	hsa-miR-1279	CLIP-seq
MIRT965954	hsa-miR-224	CLIP-seq
MIRT965959	hsa-miR-3065-3p	CLIP-seq
MIRT1986110	hsa-miR-323b-3p	CLIP-seq
MIRT1986111	hsa-miR-337-3p	CLIP-seq
MIRT1986112	hsa-miR-3545-3p	CLIP-seq
MIRT965976	hsa-miR-3676	CLIP-seq
MIRT1986113	hsa-miR-3685	CLIP-seq
MIRT1986114	hsa-miR-384	CLIP-seq
MIRT965980	hsa-miR-4312	CLIP-seq
MIRT1986115	hsa-miR-4501	CLIP-seq
MIRT1986116	hsa-miR-4645-3p	CLIP-seq
MIRT1986117	hsa-miR-4652-3p	CLIP-seq
MIRT966009	hsa-miR-507	CLIP-seq
MIRT1986118	hsa-miR-514	CLIP-seq
MIRT1986119	hsa-miR-514b-3p	CLIP-seq
MIRT1986120	hsa-miR-548l	CLIP-seq
MIRT966019	hsa-miR-557	CLIP-seq
MIRT966021	hsa-miR-582-5p	CLIP-seq
MIRT2220666	hsa-miR-1272	CLIP-seq
MIRT965943	hsa-miR-1279	CLIP-seq
MIRT2220667	hsa-miR-194	CLIP-seq
MIRT965959	hsa-miR-3065-3p	CLIP-seq
MIRT2220668	hsa-miR-3153	CLIP-seq
MIRT965967	hsa-miR-3163	CLIP-seq
MIRT965971	hsa-miR-3591-3p	CLIP-seq
MIRT965976	hsa-miR-3676	CLIP-seq
MIRT2220669	hsa-miR-3682-3p	CLIP-seq
MIRT965980	hsa-miR-4312	CLIP-seq
MIRT965981	hsa-miR-4328	CLIP-seq
MIRT965983	hsa-miR-4422	CLIP-seq
MIRT2220670	hsa-miR-493	CLIP-seq
MIRT966006	hsa-miR-494	CLIP-seq
MIRT965959	hsa-miR-3065-3p	CLIP-seq
MIRT965976	hsa-miR-3676	CLIP-seq
MIRT965988	hsa-miR-4494	CLIP-seq
MIRT966000	hsa-miR-4704-5p	CLIP-seq
MIRT2220670	hsa-miR-493	CLIP-seq
MIRT966008	hsa-miR-499a-5p	CLIP-seq
MIRT966021	hsa-miR-582-5p	CLIP-seq
MIRT966023	hsa-miR-600	CLIP-seq

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000786	Component	Nucleosome	IDA	27153538
GO:0005634	Component	Nucleus	IEA
GO:0006281	Process	DNA repair	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0032777	Component	Piccolo histone acetyltransferase complex	IBA
GO:0035267	Component	NuA4 histone acetyltransferase complex	IDA	27153538
GO:0035267	Component	NuA4 histone acetyltransferase complex	IEA
GO:0042981	Process	Regulation of apoptotic process	NAS	14966270
GO:0045893	Process	Positive regulation of DNA-templated transcription	NAS	27153538
GO:0051726	Process	Regulation of cell cycle	IMP	27153538
GO:1905168	Process	Positive regulation of double-strand break repair via homologous recombination	IDA	27153538
GO:2000779	Process	Regulation of double-strand break repair	NAS	14966270

MIM	HGNC	e!Ensembl
611000	24543	ENSG00000135999

Protein

UniProt ID

Q52LR7

Protein name

Enhancer of polycomb homolog 2 (EPC-like)

Protein function

May play a role in transcription or DNA repair.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10513	EPL1	7 → 149	Enhancer of polycomb-like	Family
PF06752	E_Pc_C	577 → 807	Enhancer of Polycomb C-terminus	Family

Sequence

MSKLSFRARALDAAKPLPIYRGKDMPDLNDCVSINRAVPQMPTGMEKEEESEHHLQRAIS
AQQVFREKKESMVIPVPEAESNVNYYNRLYKGEFKQPKQFIHIQPFNLDNEQPDYDMDSE
DETLLNRLNRKMEIKPLQFEIMIDRLEKASSNQLVTLQEAKLLLNEDDYLIKAVYDYWVR
KRKNCRGPSLIPQIKQEKRDGSTNNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRE
FSRAITILEMIKRREKTKRELLHLTLEVVEKRYHLGDYGGEILNEVKISRSEKELYATPA
TLHNGNHHKVQECKTKHPHHLSLKEEASDVVRQKKKYPKKPKAEALITSQQPTPETLPVI
NKSDIKQYDFHSSDEDEFPQVLSPVSEPEEENDPDGPCAFRRRAGCQYYAPRLDQANHSC
ENSELADLDKLRYRHCLTTLTVPRRCIGFARRRIGRGGRVIMDRISTEHDPVLKQIDPEM
LNSFSSSSQTIDFSSNFSRTNASSKHCENRLSLSEILSNIRSCRLQCFQPRLLNLQDSDS
EECTSRKPGQTVNNKRVSAASVALLNTSKNGISVTGGITEEQFQTHQQQLVQMQRQQLAQ
LQQKQQSQHSSQQTHPKAQGSSTSDCMSKTLDSASAHFAASAVVSAPVPSRSEVAKEQNT
GHNNINGVVQPSGTSKTLYSTNMALSSSPGISAVQLVRTVGHTTTNHLIPALCTSSPQTL
PMNNSCLTNAVHLNNVSVVSPVNVHINTRTSAPSPTALKLATVAASMDRVPKVTPSSAIS
SIARENHEPERLGLNGIAETTVAMEVT

Sequence length

807

Interactions

View interactions

	KEGG
	ATP-dependent chromatin remodeling

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Alzheimer Disease	Associate	21123754
Autistic Disorder	Associate	22085900
Delayed Cranial Ossification due to CBFB Haploinsufficiency	Associate	19904302
Heart Diseases	Associate	30578870
Intellectual Disability	Associate	19809484

EPC2 (enhancer of polycomb 2)