WIPI2 (WD repeat domain, phosphoinositide interacting 2)

Gene

• Entrez ID: 26100
• Gene name: WD repeat domain, phosphoinositide interacting 2
• Gene symbol: WIPI2
• Synonyms (NCBI Gene): ATG18B, Atg21, CGI-50, IDDSSA, WIPI-2
• Chromosome: 7
• Chromosome location: 7p22.1
• Summary: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI su

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs756429763	G>A	Pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052545	hsa-let-7a-5p	CLASH	23622248
MIRT040290	hsa-miR-615-3p	CLASH	23622248
MIRT037966	hsa-miR-505-5p	CLASH	23622248
MIRT258412	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT258423	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT258415	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT258410	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT258411	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT258413	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT258414	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT541022	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT541021	hsa-miR-376a-3p	PAR-CLIP	21572407
MIRT541020	hsa-miR-376b-3p	PAR-CLIP	21572407
MIRT258421	hsa-miR-6507-3p	PAR-CLIP	21572407
MIRT258417	hsa-miR-3908	PAR-CLIP	21572407
MIRT541019	hsa-miR-646	PAR-CLIP	21572407
MIRT542623	hsa-miR-4676-5p	PAR-CLIP	21572407
MIRT542622	hsa-miR-575	PAR-CLIP	21572407
MIRT541018	hsa-miR-103b	PAR-CLIP	21572407
MIRT541017	hsa-miR-4677-3p	PAR-CLIP	21572407
MIRT541016	hsa-miR-4679	PAR-CLIP	21572407
MIRT541015	hsa-miR-4786-3p	PAR-CLIP	21572407
MIRT258418	hsa-miR-3909	PAR-CLIP	21572407
MIRT258424	hsa-miR-6852-3p	PAR-CLIP	21572407
MIRT258419	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT258420	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT258422	hsa-miR-6780a-3p	PAR-CLIP	21572407
MIRT541014	hsa-miR-7843-3p	PAR-CLIP	21572407
MIRT320955	hsa-miR-3611	PAR-CLIP	21572407
MIRT258412	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT258423	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT258415	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT258410	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT258411	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT258413	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT258414	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT541022	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT541021	hsa-miR-376a-3p	PAR-CLIP	21572407
MIRT541020	hsa-miR-376b-3p	PAR-CLIP	21572407
MIRT258421	hsa-miR-6507-3p	PAR-CLIP	21572407
MIRT258417	hsa-miR-3908	PAR-CLIP	21572407
MIRT541019	hsa-miR-646	PAR-CLIP	21572407
MIRT541018	hsa-miR-103b	PAR-CLIP	21572407
MIRT541017	hsa-miR-4677-3p	PAR-CLIP	21572407
MIRT541016	hsa-miR-4679	PAR-CLIP	21572407
MIRT541015	hsa-miR-4786-3p	PAR-CLIP	21572407
MIRT258418	hsa-miR-3909	PAR-CLIP	21572407
MIRT258424	hsa-miR-6852-3p	PAR-CLIP	21572407
MIRT258419	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT258420	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT258422	hsa-miR-6780a-3p	PAR-CLIP	21572407
MIRT541014	hsa-miR-7843-3p	PAR-CLIP	21572407
MIRT320955	hsa-miR-3611	PAR-CLIP	21572407
MIRT258410	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT258412	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT258411	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT258413	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT258412	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT258423	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT258415	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT258410	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT258411	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT258413	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT258414	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT541022	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT541021	hsa-miR-376a-3p	PAR-CLIP	21572407
MIRT541020	hsa-miR-376b-3p	PAR-CLIP	21572407
MIRT258421	hsa-miR-6507-3p	PAR-CLIP	21572407
MIRT258417	hsa-miR-3908	PAR-CLIP	21572407
MIRT541019	hsa-miR-646	PAR-CLIP	21572407
MIRT542623	hsa-miR-4676-5p	PAR-CLIP	21572407
MIRT542622	hsa-miR-575	PAR-CLIP	21572407
MIRT541018	hsa-miR-103b	PAR-CLIP	21572407
MIRT541017	hsa-miR-4677-3p	PAR-CLIP	21572407
MIRT541016	hsa-miR-4679	PAR-CLIP	21572407
MIRT541015	hsa-miR-4786-3p	PAR-CLIP	21572407
MIRT258418	hsa-miR-3909	PAR-CLIP	21572407
MIRT258424	hsa-miR-6852-3p	PAR-CLIP	21572407
MIRT258419	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT258420	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT258422	hsa-miR-6780a-3p	PAR-CLIP	21572407
MIRT541014	hsa-miR-7843-3p	PAR-CLIP	21572407
MIRT320955	hsa-miR-3611	PAR-CLIP	21572407
MIRT258412	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT258423	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT258415	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT258410	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT258411	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT258413	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT258414	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT541022	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT541021	hsa-miR-376a-3p	PAR-CLIP	21572407
MIRT541020	hsa-miR-376b-3p	PAR-CLIP	21572407
MIRT258421	hsa-miR-6507-3p	PAR-CLIP	21572407
MIRT258417	hsa-miR-3908	PAR-CLIP	21572407
MIRT541019	hsa-miR-646	PAR-CLIP	21572407
MIRT541018	hsa-miR-103b	PAR-CLIP	21572407
MIRT541017	hsa-miR-4677-3p	PAR-CLIP	21572407
MIRT541016	hsa-miR-4679	PAR-CLIP	21572407
MIRT541015	hsa-miR-4786-3p	PAR-CLIP	21572407
MIRT258418	hsa-miR-3909	PAR-CLIP	21572407
MIRT258424	hsa-miR-6852-3p	PAR-CLIP	21572407
MIRT258419	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT258420	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT258422	hsa-miR-6780a-3p	PAR-CLIP	21572407
MIRT541014	hsa-miR-7843-3p	PAR-CLIP	21572407
MIRT320955	hsa-miR-3611	PAR-CLIP	21572407
MIRT1493024	hsa-miR-3183	CLIP-seq
MIRT1493025	hsa-miR-4723-3p	CLIP-seq
MIRT1493026	hsa-miR-4727-5p	CLIP-seq
MIRT1493027	hsa-miR-4769-3p	CLIP-seq
MIRT1493028	hsa-miR-593	CLIP-seq
MIRT1493029	hsa-miR-1267	CLIP-seq
MIRT1493030	hsa-miR-1303	CLIP-seq
MIRT1493031	hsa-miR-3133	CLIP-seq
MIRT1493032	hsa-miR-3150a-5p	CLIP-seq
MIRT1493033	hsa-miR-3150b-5p	CLIP-seq
MIRT1493034	hsa-miR-361-5p	CLIP-seq
MIRT1493035	hsa-miR-3616-5p	CLIP-seq
MIRT1493036	hsa-miR-3647-5p	CLIP-seq
MIRT1493037	hsa-miR-4464	CLIP-seq
MIRT1493038	hsa-miR-4670-3p	CLIP-seq
MIRT1493039	hsa-miR-4748	CLIP-seq
MIRT1493040	hsa-miR-548b-3p	CLIP-seq
MIRT1493041	hsa-miR-573	CLIP-seq
MIRT1493042	hsa-miR-574-3p	CLIP-seq
MIRT1493043	hsa-miR-626	CLIP-seq
MIRT1493044	hsa-miR-720	CLIP-seq
MIRT1493045	hsa-let-7a	CLIP-seq
MIRT1493046	hsa-let-7b	CLIP-seq
MIRT1493047	hsa-let-7c	CLIP-seq
MIRT1493048	hsa-let-7d	CLIP-seq
MIRT1493049	hsa-let-7e	CLIP-seq
MIRT1493050	hsa-let-7f	CLIP-seq
MIRT1493051	hsa-let-7g	CLIP-seq
MIRT1493052	hsa-let-7i	CLIP-seq
MIRT1493053	hsa-miR-1	CLIP-seq
MIRT1493054	hsa-miR-1228	CLIP-seq
MIRT1493055	hsa-miR-1238	CLIP-seq
MIRT1493056	hsa-miR-1252	CLIP-seq
MIRT1493057	hsa-miR-151-3p	CLIP-seq
MIRT1493058	hsa-miR-155	CLIP-seq
MIRT1493059	hsa-miR-15a	CLIP-seq
MIRT1493060	hsa-miR-15b	CLIP-seq
MIRT1493061	hsa-miR-16	CLIP-seq
MIRT1493062	hsa-miR-193a-3p	CLIP-seq
MIRT1493063	hsa-miR-193b	CLIP-seq
MIRT1493064	hsa-miR-195	CLIP-seq
MIRT1493065	hsa-miR-202	CLIP-seq
MIRT1493066	hsa-miR-2052	CLIP-seq
MIRT1493067	hsa-miR-206	CLIP-seq
MIRT1493068	hsa-miR-2467-3p	CLIP-seq
MIRT1493069	hsa-miR-2861	CLIP-seq
MIRT1493070	hsa-miR-298	CLIP-seq
MIRT1493071	hsa-miR-3158-5p	CLIP-seq
MIRT1493072	hsa-miR-3171	CLIP-seq
MIRT1493073	hsa-miR-3176	CLIP-seq
MIRT1493024	hsa-miR-3183	CLIP-seq
MIRT1493074	hsa-miR-3186-5p	CLIP-seq
MIRT1493075	hsa-miR-331-3p	CLIP-seq
MIRT1493076	hsa-miR-3607-3p	CLIP-seq
MIRT1493077	hsa-miR-3614-3p	CLIP-seq
MIRT1493035	hsa-miR-3616-5p	CLIP-seq
MIRT1493078	hsa-miR-3647-3p	CLIP-seq
MIRT1493036	hsa-miR-3647-5p	CLIP-seq
MIRT1493079	hsa-miR-365	CLIP-seq
MIRT1493080	hsa-miR-3662	CLIP-seq
MIRT1493081	hsa-miR-3667-3p	CLIP-seq
MIRT1493082	hsa-miR-3673	CLIP-seq
MIRT1493083	hsa-miR-3678-3p	CLIP-seq
MIRT1493084	hsa-miR-3686	CLIP-seq
MIRT1493085	hsa-miR-376a	CLIP-seq
MIRT1493086	hsa-miR-376b	CLIP-seq
MIRT1493087	hsa-miR-3912	CLIP-seq
MIRT1493088	hsa-miR-3922-3p	CLIP-seq
MIRT1493089	hsa-miR-3924	CLIP-seq
MIRT1493090	hsa-miR-3973	CLIP-seq
MIRT1493091	hsa-miR-424	CLIP-seq
MIRT1493092	hsa-miR-4252	CLIP-seq
MIRT1493093	hsa-miR-4292	CLIP-seq
MIRT1493094	hsa-miR-4297	CLIP-seq
MIRT1493095	hsa-miR-4304	CLIP-seq
MIRT1493096	hsa-miR-4418	CLIP-seq
MIRT1493097	hsa-miR-4456	CLIP-seq
MIRT1493098	hsa-miR-4458	CLIP-seq
MIRT1493099	hsa-miR-4500	CLIP-seq
MIRT1493100	hsa-miR-4517	CLIP-seq
MIRT1493101	hsa-miR-4524	CLIP-seq
MIRT1493102	hsa-miR-4649-3p	CLIP-seq
MIRT1493103	hsa-miR-4653-3p	CLIP-seq
MIRT1493104	hsa-miR-4722-3p	CLIP-seq
MIRT1493025	hsa-miR-4723-3p	CLIP-seq
MIRT1493026	hsa-miR-4727-5p	CLIP-seq
MIRT1493027	hsa-miR-4769-3p	CLIP-seq
MIRT1493105	hsa-miR-4778-5p	CLIP-seq
MIRT1493106	hsa-miR-4795-5p	CLIP-seq
MIRT1493107	hsa-miR-4802-5p	CLIP-seq
MIRT1493108	hsa-miR-495	CLIP-seq
MIRT1493109	hsa-miR-497	CLIP-seq
MIRT1493110	hsa-miR-503	CLIP-seq
MIRT1493111	hsa-miR-509-3-5p	CLIP-seq
MIRT1493112	hsa-miR-509-5p	CLIP-seq
MIRT1493113	hsa-miR-510	CLIP-seq
MIRT1493114	hsa-miR-520g	CLIP-seq
MIRT1493115	hsa-miR-520h	CLIP-seq
MIRT1493116	hsa-miR-521	CLIP-seq
MIRT1493117	hsa-miR-541	CLIP-seq
MIRT1493118	hsa-miR-548ac	CLIP-seq
MIRT1493119	hsa-miR-548d-3p	CLIP-seq
MIRT1493120	hsa-miR-548z	CLIP-seq
MIRT1493041	hsa-miR-573	CLIP-seq
MIRT1493121	hsa-miR-613	CLIP-seq
MIRT1493122	hsa-miR-654-5p	CLIP-seq
MIRT1493123	hsa-miR-657	CLIP-seq
MIRT1493124	hsa-miR-668	CLIP-seq
MIRT1493125	hsa-miR-933	CLIP-seq
MIRT1493126	hsa-miR-98	CLIP-seq
MIRT1493053	hsa-miR-1	CLIP-seq
MIRT2148666	hsa-miR-1233	CLIP-seq
MIRT1493055	hsa-miR-1238	CLIP-seq
MIRT1493056	hsa-miR-1252	CLIP-seq
MIRT2148667	hsa-miR-140-3p	CLIP-seq
MIRT2148668	hsa-miR-142-5p	CLIP-seq
MIRT1493057	hsa-miR-151-3p	CLIP-seq
MIRT2148669	hsa-miR-151-5p	CLIP-seq
MIRT2148670	hsa-miR-151b	CLIP-seq
MIRT1493059	hsa-miR-15a	CLIP-seq
MIRT1493060	hsa-miR-15b	CLIP-seq
MIRT1493061	hsa-miR-16	CLIP-seq
MIRT1493064	hsa-miR-195	CLIP-seq
MIRT2148671	hsa-miR-197	CLIP-seq
MIRT1493067	hsa-miR-206	CLIP-seq
MIRT2148672	hsa-miR-3121-5p	CLIP-seq
MIRT2148673	hsa-miR-3124-3p	CLIP-seq
MIRT2148674	hsa-miR-3127-5p	CLIP-seq
MIRT1493072	hsa-miR-3171	CLIP-seq
MIRT1493024	hsa-miR-3183	CLIP-seq
MIRT2148675	hsa-miR-337-3p	CLIP-seq
MIRT1493035	hsa-miR-3616-5p	CLIP-seq
MIRT1493078	hsa-miR-3647-3p	CLIP-seq
MIRT1493036	hsa-miR-3647-5p	CLIP-seq
MIRT1493080	hsa-miR-3662	CLIP-seq
MIRT1493082	hsa-miR-3673	CLIP-seq
MIRT2148676	hsa-miR-3685	CLIP-seq
MIRT1493085	hsa-miR-376a	CLIP-seq
MIRT1493086	hsa-miR-376b	CLIP-seq
MIRT2148677	hsa-miR-383	CLIP-seq
MIRT2148678	hsa-miR-384	CLIP-seq
MIRT1493090	hsa-miR-3973	CLIP-seq
MIRT2148679	hsa-miR-3978	CLIP-seq
MIRT1493091	hsa-miR-424	CLIP-seq
MIRT1493092	hsa-miR-4252	CLIP-seq
MIRT2148680	hsa-miR-4315	CLIP-seq
MIRT2148681	hsa-miR-4436a	CLIP-seq
MIRT2148682	hsa-miR-4505	CLIP-seq
MIRT2148683	hsa-miR-450a	CLIP-seq
MIRT1493101	hsa-miR-4524	CLIP-seq
MIRT2148684	hsa-miR-4645-5p	CLIP-seq
MIRT1493102	hsa-miR-4649-3p	CLIP-seq
MIRT1493103	hsa-miR-4653-3p	CLIP-seq
MIRT2148685	hsa-miR-4673	CLIP-seq
MIRT2148686	hsa-miR-4687-5p	CLIP-seq
MIRT1493025	hsa-miR-4723-3p	CLIP-seq
MIRT1493026	hsa-miR-4727-5p	CLIP-seq
MIRT2148687	hsa-miR-4738-5p	CLIP-seq
MIRT2148688	hsa-miR-4742-5p	CLIP-seq
MIRT1493027	hsa-miR-4769-3p	CLIP-seq
MIRT2148689	hsa-miR-4790-5p	CLIP-seq
MIRT1493106	hsa-miR-4795-5p	CLIP-seq
MIRT1493107	hsa-miR-4802-5p	CLIP-seq
MIRT1493109	hsa-miR-497	CLIP-seq
MIRT1493110	hsa-miR-503	CLIP-seq
MIRT1493113	hsa-miR-510	CLIP-seq
MIRT2148690	hsa-miR-513a-5p	CLIP-seq
MIRT2148691	hsa-miR-518a-5p	CLIP-seq
MIRT1493114	hsa-miR-520g	CLIP-seq
MIRT1493115	hsa-miR-520h	CLIP-seq
MIRT2148692	hsa-miR-527	CLIP-seq
MIRT1493041	hsa-miR-573	CLIP-seq
MIRT1493028	hsa-miR-593	CLIP-seq
MIRT1493121	hsa-miR-613	CLIP-seq
MIRT1493043	hsa-miR-626	CLIP-seq
MIRT2148693	hsa-miR-642a	CLIP-seq
MIRT2148694	hsa-miR-659	CLIP-seq
MIRT2148695	hsa-miR-665	CLIP-seq
MIRT1493124	hsa-miR-668	CLIP-seq
MIRT2148696	hsa-miR-766	CLIP-seq
MIRT2148697	hsa-miR-875-3p	CLIP-seq
MIRT1493053	hsa-miR-1	CLIP-seq
MIRT2369049	hsa-miR-1206	CLIP-seq
MIRT1493054	hsa-miR-1228	CLIP-seq
MIRT2148666	hsa-miR-1233	CLIP-seq
MIRT1493055	hsa-miR-1238	CLIP-seq
MIRT1493056	hsa-miR-1252	CLIP-seq
MIRT2369050	hsa-miR-1271	CLIP-seq
MIRT2369051	hsa-miR-1297	CLIP-seq
MIRT2369052	hsa-miR-1298	CLIP-seq
MIRT1493057	hsa-miR-151-3p	CLIP-seq
MIRT2148669	hsa-miR-151-5p	CLIP-seq
MIRT2148670	hsa-miR-151b	CLIP-seq
MIRT1493059	hsa-miR-15a	CLIP-seq
MIRT1493060	hsa-miR-15b	CLIP-seq
MIRT1493061	hsa-miR-16	CLIP-seq
MIRT1493062	hsa-miR-193a-3p	CLIP-seq
MIRT1493063	hsa-miR-193b	CLIP-seq
MIRT1493064	hsa-miR-195	CLIP-seq
MIRT2148671	hsa-miR-197	CLIP-seq
MIRT2369053	hsa-miR-199a-5p	CLIP-seq
MIRT2369054	hsa-miR-199b-5p	CLIP-seq
MIRT1493065	hsa-miR-202	CLIP-seq
MIRT1493066	hsa-miR-2052	CLIP-seq
MIRT1493067	hsa-miR-206	CLIP-seq
MIRT2369055	hsa-miR-2117	CLIP-seq
MIRT1493068	hsa-miR-2467-3p	CLIP-seq
MIRT2369056	hsa-miR-26a	CLIP-seq
MIRT2369057	hsa-miR-26b	CLIP-seq
MIRT1493069	hsa-miR-2861	CLIP-seq
MIRT1493070	hsa-miR-298	CLIP-seq
MIRT2369058	hsa-miR-300	CLIP-seq
MIRT1493071	hsa-miR-3158-5p	CLIP-seq
MIRT1493072	hsa-miR-3171	CLIP-seq
MIRT1493073	hsa-miR-3176	CLIP-seq
MIRT1493024	hsa-miR-3183	CLIP-seq
MIRT1493075	hsa-miR-331-3p	CLIP-seq
MIRT1493035	hsa-miR-3616-5p	CLIP-seq
MIRT1493078	hsa-miR-3647-3p	CLIP-seq
MIRT1493036	hsa-miR-3647-5p	CLIP-seq
MIRT2369059	hsa-miR-3652	CLIP-seq
MIRT1493080	hsa-miR-3662	CLIP-seq
MIRT2369060	hsa-miR-3665	CLIP-seq
MIRT1493082	hsa-miR-3673	CLIP-seq
MIRT1493083	hsa-miR-3678-3p	CLIP-seq
MIRT2369061	hsa-miR-3689a-3p	CLIP-seq
MIRT2369062	hsa-miR-3689c	CLIP-seq
MIRT1493085	hsa-miR-376a	CLIP-seq
MIRT1493086	hsa-miR-376b	CLIP-seq
MIRT2369063	hsa-miR-381	CLIP-seq
MIRT2148677	hsa-miR-383	CLIP-seq
MIRT1493088	hsa-miR-3922-3p	CLIP-seq
MIRT1493090	hsa-miR-3973	CLIP-seq
MIRT2148679	hsa-miR-3978	CLIP-seq
MIRT2369064	hsa-miR-412	CLIP-seq
MIRT1493091	hsa-miR-424	CLIP-seq
MIRT1493092	hsa-miR-4252	CLIP-seq
MIRT2369065	hsa-miR-4255	CLIP-seq
MIRT2369066	hsa-miR-4257	CLIP-seq
MIRT2369067	hsa-miR-4273	CLIP-seq
MIRT1493093	hsa-miR-4292	CLIP-seq
MIRT1493096	hsa-miR-4418	CLIP-seq
MIRT2369068	hsa-miR-4430	CLIP-seq
MIRT1493097	hsa-miR-4456	CLIP-seq
MIRT2369069	hsa-miR-4465	CLIP-seq
MIRT2148682	hsa-miR-4505	CLIP-seq
MIRT2148683	hsa-miR-450a	CLIP-seq
MIRT1493101	hsa-miR-4524	CLIP-seq
MIRT2148684	hsa-miR-4645-5p	CLIP-seq
MIRT1493102	hsa-miR-4649-3p	CLIP-seq
MIRT1493103	hsa-miR-4653-3p	CLIP-seq
MIRT2369070	hsa-miR-4666-3p	CLIP-seq
MIRT2369071	hsa-miR-4668-5p	CLIP-seq
MIRT2148685	hsa-miR-4673	CLIP-seq
MIRT2369072	hsa-miR-4707-5p	CLIP-seq
MIRT1493025	hsa-miR-4723-3p	CLIP-seq
MIRT1493026	hsa-miR-4727-5p	CLIP-seq
MIRT2369073	hsa-miR-4728-3p	CLIP-seq
MIRT2369074	hsa-miR-4728-5p	CLIP-seq
MIRT2369075	hsa-miR-4729	CLIP-seq
MIRT2369076	hsa-miR-4733-5p	CLIP-seq
MIRT2369077	hsa-miR-4736	CLIP-seq
MIRT2148687	hsa-miR-4738-5p	CLIP-seq
MIRT2148688	hsa-miR-4742-5p	CLIP-seq
MIRT2369078	hsa-miR-4767	CLIP-seq
MIRT1493027	hsa-miR-4769-3p	CLIP-seq
MIRT2369079	hsa-miR-4773	CLIP-seq
MIRT2369080	hsa-miR-4775	CLIP-seq
MIRT2369081	hsa-miR-4785	CLIP-seq
MIRT2369082	hsa-miR-4789-5p	CLIP-seq
MIRT1493106	hsa-miR-4795-5p	CLIP-seq
MIRT2369083	hsa-miR-4796-3p	CLIP-seq
MIRT1493107	hsa-miR-4802-5p	CLIP-seq
MIRT1493109	hsa-miR-497	CLIP-seq
MIRT2369084	hsa-miR-498	CLIP-seq
MIRT1493110	hsa-miR-503	CLIP-seq
MIRT2369085	hsa-miR-508-5p	CLIP-seq
MIRT1493111	hsa-miR-509-3-5p	CLIP-seq
MIRT1493112	hsa-miR-509-5p	CLIP-seq
MIRT1493113	hsa-miR-510	CLIP-seq
MIRT2148690	hsa-miR-513a-5p	CLIP-seq
MIRT2148691	hsa-miR-518a-5p	CLIP-seq
MIRT1493114	hsa-miR-520g	CLIP-seq
MIRT1493115	hsa-miR-520h	CLIP-seq
MIRT1493116	hsa-miR-521	CLIP-seq
MIRT2148692	hsa-miR-527	CLIP-seq
MIRT1493117	hsa-miR-541	CLIP-seq
MIRT2369086	hsa-miR-545	CLIP-seq
MIRT1493118	hsa-miR-548ac	CLIP-seq
MIRT1493119	hsa-miR-548d-3p	CLIP-seq
MIRT1493120	hsa-miR-548z	CLIP-seq
MIRT2369087	hsa-miR-564	CLIP-seq
MIRT2369088	hsa-miR-570	CLIP-seq
MIRT1493041	hsa-miR-573	CLIP-seq
MIRT2369089	hsa-miR-579	CLIP-seq
MIRT2369090	hsa-miR-590-3p	CLIP-seq
MIRT2369091	hsa-miR-604	CLIP-seq
MIRT1493121	hsa-miR-613	CLIP-seq
MIRT2369092	hsa-miR-647	CLIP-seq
MIRT1493122	hsa-miR-654-5p	CLIP-seq
MIRT1493123	hsa-miR-657	CLIP-seq
MIRT1493124	hsa-miR-668	CLIP-seq
MIRT2369093	hsa-miR-671-5p	CLIP-seq
MIRT2148696	hsa-miR-766	CLIP-seq
MIRT2369094	hsa-miR-767-3p	CLIP-seq
MIRT2148697	hsa-miR-875-3p	CLIP-seq
MIRT1493125	hsa-miR-933	CLIP-seq
MIRT2369095	hsa-miR-944	CLIP-seq
MIRT2369096	hsa-miR-96	CLIP-seq
MIRT1493059	hsa-miR-15a	CLIP-seq
MIRT1493060	hsa-miR-15b	CLIP-seq
MIRT1493061	hsa-miR-16	CLIP-seq
MIRT1493064	hsa-miR-195	CLIP-seq
MIRT1493085	hsa-miR-376a	CLIP-seq
MIRT1493086	hsa-miR-376b	CLIP-seq
MIRT1493090	hsa-miR-3973	CLIP-seq
MIRT1493091	hsa-miR-424	CLIP-seq
MIRT1493101	hsa-miR-4524	CLIP-seq
MIRT1493109	hsa-miR-497	CLIP-seq
MIRT1493110	hsa-miR-503	CLIP-seq
MIRT1493114	hsa-miR-520g	CLIP-seq
MIRT1493115	hsa-miR-520h	CLIP-seq
MIRT2148669	hsa-miR-151-5p	CLIP-seq
MIRT2148670	hsa-miR-151b	CLIP-seq
MIRT2148691	hsa-miR-518a-5p	CLIP-seq
MIRT2148692	hsa-miR-527	CLIP-seq
MIRT2369049	hsa-miR-1206	CLIP-seq
MIRT2369050	hsa-miR-1271	CLIP-seq
MIRT2662503	hsa-miR-133a	CLIP-seq
MIRT2662504	hsa-miR-133b	CLIP-seq
MIRT2662505	hsa-miR-141	CLIP-seq
MIRT2148669	hsa-miR-151-5p	CLIP-seq
MIRT2148670	hsa-miR-151b	CLIP-seq
MIRT2662506	hsa-miR-182	CLIP-seq
MIRT1493062	hsa-miR-193a-3p	CLIP-seq
MIRT1493063	hsa-miR-193b	CLIP-seq
MIRT2148671	hsa-miR-197	CLIP-seq
MIRT2662507	hsa-miR-200a	CLIP-seq
MIRT1493070	hsa-miR-298	CLIP-seq
MIRT1493071	hsa-miR-3158-5p	CLIP-seq
MIRT1493073	hsa-miR-3176	CLIP-seq
MIRT2369059	hsa-miR-3652	CLIP-seq
MIRT2369060	hsa-miR-3665	CLIP-seq
MIRT1493088	hsa-miR-3922-3p	CLIP-seq
MIRT1493089	hsa-miR-3924	CLIP-seq
MIRT2148679	hsa-miR-3978	CLIP-seq
MIRT2369064	hsa-miR-412	CLIP-seq
MIRT2662508	hsa-miR-4281	CLIP-seq
MIRT2662509	hsa-miR-4282	CLIP-seq
MIRT1493095	hsa-miR-4304	CLIP-seq
MIRT2662510	hsa-miR-4311	CLIP-seq
MIRT1493096	hsa-miR-4418	CLIP-seq
MIRT2369068	hsa-miR-4430	CLIP-seq
MIRT2662511	hsa-miR-4470	CLIP-seq
MIRT2148682	hsa-miR-4505	CLIP-seq
MIRT2148683	hsa-miR-450a	CLIP-seq
MIRT2369073	hsa-miR-4728-3p	CLIP-seq
MIRT2369077	hsa-miR-4736	CLIP-seq
MIRT2662512	hsa-miR-4760-3p	CLIP-seq
MIRT2369078	hsa-miR-4767	CLIP-seq
MIRT2369080	hsa-miR-4775	CLIP-seq
MIRT2369083	hsa-miR-4796-3p	CLIP-seq
MIRT2662513	hsa-miR-486-3p	CLIP-seq
MIRT1493108	hsa-miR-495	CLIP-seq
MIRT1493111	hsa-miR-509-3-5p	CLIP-seq
MIRT1493112	hsa-miR-509-5p	CLIP-seq
MIRT2662514	hsa-miR-5096	CLIP-seq
MIRT2148691	hsa-miR-518a-5p	CLIP-seq
MIRT1493116	hsa-miR-521	CLIP-seq
MIRT2148692	hsa-miR-527	CLIP-seq
MIRT1493118	hsa-miR-548ac	CLIP-seq
MIRT1493119	hsa-miR-548d-3p	CLIP-seq
MIRT1493120	hsa-miR-548z	CLIP-seq
MIRT2369087	hsa-miR-564	CLIP-seq
MIRT2369088	hsa-miR-570	CLIP-seq
MIRT2369090	hsa-miR-590-3p	CLIP-seq
MIRT1493124	hsa-miR-668	CLIP-seq
MIRT2662515	hsa-miR-873	CLIP-seq
MIRT2148697	hsa-miR-875-3p	CLIP-seq
MIRT1493125	hsa-miR-933	CLIP-seq
MIRT2369096	hsa-miR-96	CLIP-seq
MIRT2369049	hsa-miR-1206	CLIP-seq
MIRT2369050	hsa-miR-1271	CLIP-seq
MIRT2662503	hsa-miR-133a	CLIP-seq
MIRT2662504	hsa-miR-133b	CLIP-seq
MIRT2662505	hsa-miR-141	CLIP-seq
MIRT2148669	hsa-miR-151-5p	CLIP-seq
MIRT2148670	hsa-miR-151b	CLIP-seq
MIRT2662506	hsa-miR-182	CLIP-seq
MIRT1493062	hsa-miR-193a-3p	CLIP-seq
MIRT1493063	hsa-miR-193b	CLIP-seq
MIRT2148671	hsa-miR-197	CLIP-seq
MIRT2662507	hsa-miR-200a	CLIP-seq
MIRT1493070	hsa-miR-298	CLIP-seq
MIRT1493071	hsa-miR-3158-5p	CLIP-seq
MIRT1493073	hsa-miR-3176	CLIP-seq
MIRT2369059	hsa-miR-3652	CLIP-seq
MIRT2369060	hsa-miR-3665	CLIP-seq
MIRT1493088	hsa-miR-3922-3p	CLIP-seq
MIRT1493089	hsa-miR-3924	CLIP-seq
MIRT2148679	hsa-miR-3978	CLIP-seq
MIRT2369064	hsa-miR-412	CLIP-seq
MIRT2695241	hsa-miR-4267	CLIP-seq
MIRT2695242	hsa-miR-4277	CLIP-seq
MIRT2662508	hsa-miR-4281	CLIP-seq
MIRT2662509	hsa-miR-4282	CLIP-seq
MIRT1493095	hsa-miR-4304	CLIP-seq
MIRT2662510	hsa-miR-4311	CLIP-seq
MIRT1493096	hsa-miR-4418	CLIP-seq
MIRT2369068	hsa-miR-4430	CLIP-seq
MIRT2662511	hsa-miR-4470	CLIP-seq
MIRT2148682	hsa-miR-4505	CLIP-seq
MIRT2148683	hsa-miR-450a	CLIP-seq
MIRT2369073	hsa-miR-4728-3p	CLIP-seq
MIRT2369077	hsa-miR-4736	CLIP-seq
MIRT2662512	hsa-miR-4760-3p	CLIP-seq
MIRT2369078	hsa-miR-4767	CLIP-seq
MIRT2369080	hsa-miR-4775	CLIP-seq
MIRT2369083	hsa-miR-4796-3p	CLIP-seq
MIRT2662513	hsa-miR-486-3p	CLIP-seq
MIRT1493108	hsa-miR-495	CLIP-seq
MIRT2369085	hsa-miR-508-5p	CLIP-seq
MIRT1493111	hsa-miR-509-3-5p	CLIP-seq
MIRT1493112	hsa-miR-509-5p	CLIP-seq
MIRT2662514	hsa-miR-5096	CLIP-seq
MIRT2148691	hsa-miR-518a-5p	CLIP-seq
MIRT1493116	hsa-miR-521	CLIP-seq
MIRT2148692	hsa-miR-527	CLIP-seq
MIRT1493118	hsa-miR-548ac	CLIP-seq
MIRT1493119	hsa-miR-548d-3p	CLIP-seq
MIRT1493120	hsa-miR-548z	CLIP-seq
MIRT2369087	hsa-miR-564	CLIP-seq
MIRT2369088	hsa-miR-570	CLIP-seq
MIRT2369090	hsa-miR-590-3p	CLIP-seq
MIRT1493124	hsa-miR-668	CLIP-seq
MIRT2662515	hsa-miR-873	CLIP-seq
MIRT2148697	hsa-miR-875-3p	CLIP-seq
MIRT1493125	hsa-miR-933	CLIP-seq
MIRT2369096	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000045	Process	Autophagosome assembly	IDA	28890335
GO:0000045	Process	Autophagosome assembly	IMP	20505359, 28561066
GO:0000407	Component	Phagophore assembly site	IDA	22456507, 28561066, 33499712
GO:0000407	Component	Phagophore assembly site	IEA
GO:0000422	Process	Autophagy of mitochondrion	IBA
GO:0000425	Process	Pexophagy	IBA
GO:0005515	Function	Protein binding	IPI	21044950, 21575909, 25416956, 28561066, 28890335, 32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005776	Component	Autophagosome	IDA	20505359
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	20505359
GO:0005829	Component	Cytosol	TAS
GO:0006914	Process	Autophagy	IEA
GO:0006950	Process	Response to stress	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0009267	Process	Cellular response to starvation	IDA	28561066
GO:0010314	Function	Phosphatidylinositol-5-phosphate binding	IDA	25578879
GO:0016020	Component	Membrane	IDA	25578879
GO:0016020	Component	Membrane	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IBA
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	IBA
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	IDA	20505359, 25578879, 28561066
GO:0032266	Function	Phosphatidylinositol-3-phosphate binding	IEA
GO:0032991	Component	Protein-containing complex	IDA
GO:0034045	Component	Phagophore assembly site membrane	IBA
GO:0034045	Component	Phagophore assembly site membrane	IDA	20505359
GO:0034045	Component	Phagophore assembly site membrane	IEA
GO:0034497	Process	Protein localization to phagophore assembly site	IBA
GO:0034497	Process	Protein localization to phagophore assembly site	IEA
GO:0034497	Process	Protein localization to phagophore assembly site	IMP	28561066
GO:0044804	Process	Nucleophagy	IBA
GO:0061723	Process	Glycophagy	IBA
GO:0080025	Function	Phosphatidylinositol-3,5-bisphosphate binding	IBA
GO:0080025	Function	Phosphatidylinositol-3,5-bisphosphate binding	IDA	20505359, 28561066
GO:0097352	Process	Autophagosome maturation	IMP	20505359

Other IDs

• MIM: 609225
• HGNC: 32225
• e!Ensembl: ENSG00000157954

Protein

• UniProt ID: Q9Y4P8
• Protein name: WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)
• Protein function: Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation (PubMed:20505359, PubMed:28561066). Involve
• PDB: 7F69, 7MU2, 7XFR
• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors. {ECO:0000269|PubMed:15602573, ECO:0000269|PubMed:20505359}.
• Sequence:

  MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
  VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
  AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
  IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
  FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
  ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
  PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
  DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD

• Sequence length: 454

Pathways

KEGG:

Autophagy - other
Autophagy - animal
Alzheimer disease
Amyotrophic lateral sclerosis
Huntington disease
Spinocerebellar ataxia
Pathways of neurodegeneration - multiple diseases
Shigellosis

Reactome:

Macroautophagy

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Intellectual developmental disorder with short stature and variable skeletal anomalies	Pathogenic	rs2115280647, rs756429763	RCV001774826 RCV000782105

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Familial cancer of breast	Benign	rs4587243	RCV005937152
WIPI2-related disorder	Likely benign; Benign	rs138018731, rs4587243, rs1134489, rs41280678, rs150356826, rs11760558, rs139158009, rs780256529, rs147945082, rs28605777, rs34104542, rs35062616, rs61736544, rs146199183, rs191643610	RCV003966421 RCV003974529 RCV003974540 RCV003974109 RCV003911758 RCV003916990 RCV003922269 RCV003962285 RCV003976553 RCV003926090 RCV003926091 RCV003915815 RCV003928480 RCV003910528 RCV003955849

Associations from Text Mining
Disease Name	Relationship Type	References
Amyotrophic Lateral Sclerosis	Associate	37639066
Carcinogenesis	Associate	24991767
Carcinoma Hepatocellular	Associate	32323845
Colorectal Neoplasms	Associate	32468035, 33357130
Developmental Disabilities	Associate	30968111
Growth Disorders	Associate	30968111
Leukemia Promyelocytic Acute	Inhibit	24991767
Neoplasms	Associate	24991767
Neoplasms	Stimulate	32323845
Pancreatic Neoplasms	Associate	35199935
Tuberculosis	Associate	32365959
Urinary Bladder Neoplasms	Associate	28381171