Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	26084
Gene name Gene Name - the full gene name approved by the HGNC.	Rho guanine nucleotide exchange factor 26
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ARHGEF26
Synonyms (NCBI Gene) Gene synonyms aliases	CSGEF, HMFN1864, SGEF
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q25.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of

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miRTarBase ID	miRNA	Experiments	Reference
MIRT024552	hsa-miR-215-5p	Microarray	19074876
MIRT026408	hsa-miR-192-5p	Microarray	19074876
MIRT090904	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT090905	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT090900	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT090901	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT090912	hsa-miR-3666	PAR-CLIP	21572407
MIRT090898	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT090910	hsa-miR-4295	PAR-CLIP	21572407
MIRT090907	hsa-miR-3121-3p	PAR-CLIP	21572407
MIRT090915	hsa-miR-3974	PAR-CLIP	21572407
MIRT090911	hsa-miR-4301	PAR-CLIP	21572407
MIRT559515	hsa-miR-3119	PAR-CLIP	21572407
MIRT090896	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT090897	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT559514	hsa-miR-124-3p	PAR-CLIP	21572407
MIRT559513	hsa-miR-506-3p	PAR-CLIP	21572407
MIRT090916	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT559512	hsa-miR-4473	PAR-CLIP	21572407
MIRT090899	hsa-miR-188-3p	PAR-CLIP	21572407
MIRT090906	hsa-miR-1260a	PAR-CLIP	21572407
MIRT090909	hsa-miR-1260b	PAR-CLIP	21572407
MIRT090908	hsa-miR-3156-3p	PAR-CLIP	21572407
MIRT090913	hsa-miR-4452	PAR-CLIP	21572407
MIRT559511	hsa-miR-3591-5p	PAR-CLIP	21572407
MIRT090904	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT090905	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT090900	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT090901	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT090912	hsa-miR-3666	PAR-CLIP	21572407
MIRT090898	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT090910	hsa-miR-4295	PAR-CLIP	21572407
MIRT090907	hsa-miR-3121-3p	PAR-CLIP	21572407
MIRT090915	hsa-miR-3974	PAR-CLIP	21572407
MIRT090911	hsa-miR-4301	PAR-CLIP	21572407
MIRT559515	hsa-miR-3119	PAR-CLIP	21572407
MIRT090896	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT090897	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT559514	hsa-miR-124-3p	PAR-CLIP	21572407
MIRT559513	hsa-miR-506-3p	PAR-CLIP	21572407
MIRT090916	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT559512	hsa-miR-4473	PAR-CLIP	21572407
MIRT090899	hsa-miR-188-3p	PAR-CLIP	21572407
MIRT090906	hsa-miR-1260a	PAR-CLIP	21572407
MIRT090909	hsa-miR-1260b	PAR-CLIP	21572407
MIRT090908	hsa-miR-3156-3p	PAR-CLIP	21572407
MIRT090913	hsa-miR-4452	PAR-CLIP	21572407
MIRT559511	hsa-miR-3591-5p	PAR-CLIP	21572407
MIRT795628	hsa-miR-1183	CLIP-seq
MIRT795629	hsa-miR-1208	CLIP-seq
MIRT795630	hsa-miR-1225-5p	CLIP-seq
MIRT795631	hsa-miR-125a-5p	CLIP-seq
MIRT795632	hsa-miR-125b	CLIP-seq
MIRT795633	hsa-miR-1268	CLIP-seq
MIRT795634	hsa-miR-1268b	CLIP-seq
MIRT795635	hsa-miR-1272	CLIP-seq
MIRT795636	hsa-miR-1273g	CLIP-seq
MIRT795637	hsa-miR-1285	CLIP-seq
MIRT795638	hsa-miR-130a	CLIP-seq
MIRT795639	hsa-miR-130b	CLIP-seq
MIRT795640	hsa-miR-147	CLIP-seq
MIRT795641	hsa-miR-1827	CLIP-seq
MIRT795642	hsa-miR-19a	CLIP-seq
MIRT795643	hsa-miR-19b	CLIP-seq
MIRT795644	hsa-miR-204	CLIP-seq
MIRT795645	hsa-miR-211	CLIP-seq
MIRT795646	hsa-miR-2276	CLIP-seq
MIRT795647	hsa-miR-24	CLIP-seq
MIRT795648	hsa-miR-2467-3p	CLIP-seq
MIRT795649	hsa-miR-301a	CLIP-seq
MIRT795650	hsa-miR-301b	CLIP-seq
MIRT795651	hsa-miR-3138	CLIP-seq
MIRT795652	hsa-miR-3148	CLIP-seq
MIRT795653	hsa-miR-3165	CLIP-seq
MIRT795654	hsa-miR-3168	CLIP-seq
MIRT795655	hsa-miR-3177-5p	CLIP-seq
MIRT795656	hsa-miR-3187-5p	CLIP-seq
MIRT795657	hsa-miR-34b	CLIP-seq
MIRT795658	hsa-miR-3545-3p	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT795660	hsa-miR-3616-3p	CLIP-seq
MIRT795661	hsa-miR-3616-5p	CLIP-seq
MIRT795662	hsa-miR-3619-3p	CLIP-seq
MIRT795663	hsa-miR-3647-5p	CLIP-seq
MIRT795664	hsa-miR-3664-3p	CLIP-seq
MIRT795665	hsa-miR-3667-3p	CLIP-seq
MIRT795666	hsa-miR-3680	CLIP-seq
MIRT795667	hsa-miR-3681	CLIP-seq
MIRT795668	hsa-miR-3689a-3p	CLIP-seq
MIRT795669	hsa-miR-3689c	CLIP-seq
MIRT795670	hsa-miR-3911	CLIP-seq
MIRT795671	hsa-miR-3926	CLIP-seq
MIRT795672	hsa-miR-3929	CLIP-seq
MIRT795673	hsa-miR-3940-3p	CLIP-seq
MIRT795674	hsa-miR-4257	CLIP-seq
MIRT795675	hsa-miR-4274	CLIP-seq
MIRT795676	hsa-miR-4284	CLIP-seq
MIRT795677	hsa-miR-4318	CLIP-seq
MIRT795678	hsa-miR-4319	CLIP-seq
MIRT795679	hsa-miR-4330	CLIP-seq
MIRT795680	hsa-miR-4419b	CLIP-seq
MIRT795681	hsa-miR-4420	CLIP-seq
MIRT795682	hsa-miR-4424	CLIP-seq
MIRT795683	hsa-miR-4433	CLIP-seq
MIRT795684	hsa-miR-4436b-3p	CLIP-seq
MIRT795685	hsa-miR-4440	CLIP-seq
MIRT795686	hsa-miR-4446-5p	CLIP-seq
MIRT795687	hsa-miR-4459	CLIP-seq
MIRT795688	hsa-miR-4476	CLIP-seq
MIRT795689	hsa-miR-4477b	CLIP-seq
MIRT795690	hsa-miR-4478	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT795692	hsa-miR-4505	CLIP-seq
MIRT795693	hsa-miR-4527	CLIP-seq
MIRT795694	hsa-miR-454	CLIP-seq
MIRT795695	hsa-miR-4649-3p	CLIP-seq
MIRT795696	hsa-miR-4653-3p	CLIP-seq
MIRT795697	hsa-miR-4693-5p	CLIP-seq
MIRT795698	hsa-miR-4695-3p	CLIP-seq
MIRT795699	hsa-miR-4699-3p	CLIP-seq
MIRT795700	hsa-miR-4721	CLIP-seq
MIRT795701	hsa-miR-4722-5p	CLIP-seq
MIRT795702	hsa-miR-4728-3p	CLIP-seq
MIRT795703	hsa-miR-4728-5p	CLIP-seq
MIRT795704	hsa-miR-4732-3p	CLIP-seq
MIRT795705	hsa-miR-4735-5p	CLIP-seq
MIRT795706	hsa-miR-4753-5p	CLIP-seq
MIRT795707	hsa-miR-4755-5p	CLIP-seq
MIRT795708	hsa-miR-4761-5p	CLIP-seq
MIRT795709	hsa-miR-4762-3p	CLIP-seq
MIRT795710	hsa-miR-4762-5p	CLIP-seq
MIRT795711	hsa-miR-4766-5p	CLIP-seq
MIRT795712	hsa-miR-4768-3p	CLIP-seq
MIRT795713	hsa-miR-4772-3p	CLIP-seq
MIRT795714	hsa-miR-4775	CLIP-seq
MIRT795715	hsa-miR-4776-5p	CLIP-seq
MIRT795716	hsa-miR-4777-3p	CLIP-seq
MIRT795717	hsa-miR-4778-5p	CLIP-seq
MIRT795718	hsa-miR-4786-5p	CLIP-seq
MIRT795719	hsa-miR-4793-5p	CLIP-seq
MIRT795720	hsa-miR-4795-5p	CLIP-seq
MIRT795721	hsa-miR-4798-3p	CLIP-seq
MIRT795722	hsa-miR-4800-5p	CLIP-seq
MIRT795723	hsa-miR-485-5p	CLIP-seq
MIRT795724	hsa-miR-502-5p	CLIP-seq
MIRT795725	hsa-miR-513c	CLIP-seq
MIRT795726	hsa-miR-514b-5p	CLIP-seq
MIRT795727	hsa-miR-517a	CLIP-seq
MIRT795728	hsa-miR-517b	CLIP-seq
MIRT795729	hsa-miR-517c	CLIP-seq
MIRT795730	hsa-miR-548a-3p	CLIP-seq
MIRT795731	hsa-miR-548a-5p	CLIP-seq
MIRT795732	hsa-miR-548ab	CLIP-seq
MIRT795733	hsa-miR-548ak	CLIP-seq
MIRT795734	hsa-miR-548b-5p	CLIP-seq
MIRT795735	hsa-miR-548c-5p	CLIP-seq
MIRT795736	hsa-miR-548d-5p	CLIP-seq
MIRT795737	hsa-miR-548e	CLIP-seq
MIRT795738	hsa-miR-548f	CLIP-seq
MIRT795739	hsa-miR-548h	CLIP-seq
MIRT795740	hsa-miR-548i	CLIP-seq
MIRT795741	hsa-miR-548j	CLIP-seq
MIRT795742	hsa-miR-548n	CLIP-seq
MIRT795743	hsa-miR-548s	CLIP-seq
MIRT795744	hsa-miR-548w	CLIP-seq
MIRT795745	hsa-miR-548y	CLIP-seq
MIRT795746	hsa-miR-559	CLIP-seq
MIRT795747	hsa-miR-561	CLIP-seq
MIRT795748	hsa-miR-562	CLIP-seq
MIRT795749	hsa-miR-564	CLIP-seq
MIRT795750	hsa-miR-573	CLIP-seq
MIRT795751	hsa-miR-585	CLIP-seq
MIRT795752	hsa-miR-590-3p	CLIP-seq
MIRT795753	hsa-miR-595	CLIP-seq
MIRT795754	hsa-miR-612	CLIP-seq
MIRT795755	hsa-miR-617	CLIP-seq
MIRT795756	hsa-miR-623	CLIP-seq
MIRT795757	hsa-miR-628-5p	CLIP-seq
MIRT795758	hsa-miR-644	CLIP-seq
MIRT795759	hsa-miR-670	CLIP-seq
MIRT795760	hsa-miR-767-3p	CLIP-seq
MIRT795761	hsa-miR-890	CLIP-seq
MIRT795762	hsa-miR-940	CLIP-seq
MIRT1934984	hsa-miR-1178	CLIP-seq
MIRT795628	hsa-miR-1183	CLIP-seq
MIRT1934985	hsa-miR-1202	CLIP-seq
MIRT1934986	hsa-miR-128	CLIP-seq
MIRT795637	hsa-miR-1285	CLIP-seq
MIRT1934987	hsa-miR-137	CLIP-seq
MIRT1934988	hsa-miR-142-3p	CLIP-seq
MIRT795642	hsa-miR-19a	CLIP-seq
MIRT795643	hsa-miR-19b	CLIP-seq
MIRT795644	hsa-miR-204	CLIP-seq
MIRT795645	hsa-miR-211	CLIP-seq
MIRT1934989	hsa-miR-22	CLIP-seq
MIRT1934990	hsa-miR-223	CLIP-seq
MIRT795647	hsa-miR-24	CLIP-seq
MIRT795648	hsa-miR-2467-3p	CLIP-seq
MIRT1934991	hsa-miR-27a	CLIP-seq
MIRT1934992	hsa-miR-27b	CLIP-seq
MIRT1934993	hsa-miR-3120-3p	CLIP-seq
MIRT1934994	hsa-miR-3126-5p	CLIP-seq
MIRT1934995	hsa-miR-3140-3p	CLIP-seq
MIRT1934996	hsa-miR-3143	CLIP-seq
MIRT795655	hsa-miR-3177-5p	CLIP-seq
MIRT795656	hsa-miR-3187-5p	CLIP-seq
MIRT1934997	hsa-miR-320a	CLIP-seq
MIRT1934998	hsa-miR-320b	CLIP-seq
MIRT1934999	hsa-miR-320c	CLIP-seq
MIRT1935000	hsa-miR-320d	CLIP-seq
MIRT1935001	hsa-miR-323b-3p	CLIP-seq
MIRT1935002	hsa-miR-330-3p	CLIP-seq
MIRT1935003	hsa-miR-331-5p	CLIP-seq
MIRT1935004	hsa-miR-340	CLIP-seq
MIRT1935005	hsa-miR-361-5p	CLIP-seq
MIRT795665	hsa-miR-3667-3p	CLIP-seq
MIRT1935006	hsa-miR-3671	CLIP-seq
MIRT795666	hsa-miR-3680	CLIP-seq
MIRT795672	hsa-miR-3929	CLIP-seq
MIRT1935007	hsa-miR-3972	CLIP-seq
MIRT1935008	hsa-miR-410	CLIP-seq
MIRT795674	hsa-miR-4257	CLIP-seq
MIRT795676	hsa-miR-4284	CLIP-seq
MIRT1935009	hsa-miR-4328	CLIP-seq
MIRT795679	hsa-miR-4330	CLIP-seq
MIRT795680	hsa-miR-4419b	CLIP-seq
MIRT1935010	hsa-miR-4427	CLIP-seq
MIRT1935011	hsa-miR-4429	CLIP-seq
MIRT795690	hsa-miR-4478	CLIP-seq
MIRT795692	hsa-miR-4505	CLIP-seq
MIRT1935012	hsa-miR-4522	CLIP-seq
MIRT1935013	hsa-miR-4640-5p	CLIP-seq
MIRT1935014	hsa-miR-4659a-5p	CLIP-seq
MIRT1935015	hsa-miR-4659b-5p	CLIP-seq
MIRT1935016	hsa-miR-4678	CLIP-seq
MIRT1935017	hsa-miR-4680-3p	CLIP-seq
MIRT1935018	hsa-miR-4691-5p	CLIP-seq
MIRT795697	hsa-miR-4693-5p	CLIP-seq
MIRT795698	hsa-miR-4695-3p	CLIP-seq
MIRT1935019	hsa-miR-4714-5p	CLIP-seq
MIRT1935020	hsa-miR-4724-3p	CLIP-seq
MIRT1935021	hsa-miR-4726-5p	CLIP-seq
MIRT1935022	hsa-miR-4738-3p	CLIP-seq
MIRT1935023	hsa-miR-4747-5p	CLIP-seq
MIRT795707	hsa-miR-4755-5p	CLIP-seq
MIRT1935024	hsa-miR-4760-3p	CLIP-seq
MIRT795708	hsa-miR-4761-5p	CLIP-seq
MIRT795711	hsa-miR-4766-5p	CLIP-seq
MIRT1935025	hsa-miR-4776-3p	CLIP-seq
MIRT1935026	hsa-miR-4795-3p	CLIP-seq
MIRT795721	hsa-miR-4798-3p	CLIP-seq
MIRT795724	hsa-miR-502-5p	CLIP-seq
MIRT1935027	hsa-miR-513a-5p	CLIP-seq
MIRT795725	hsa-miR-513c	CLIP-seq
MIRT795726	hsa-miR-514b-5p	CLIP-seq
MIRT1935028	hsa-miR-543	CLIP-seq
MIRT795749	hsa-miR-564	CLIP-seq
MIRT1935029	hsa-miR-607	CLIP-seq
MIRT795754	hsa-miR-612	CLIP-seq
MIRT795756	hsa-miR-623	CLIP-seq
MIRT1935030	hsa-miR-627	CLIP-seq
MIRT1935031	hsa-miR-648	CLIP-seq
MIRT795629	hsa-miR-1208	CLIP-seq
MIRT2174776	hsa-miR-1228	CLIP-seq
MIRT2174777	hsa-miR-1251	CLIP-seq
MIRT795631	hsa-miR-125a-5p	CLIP-seq
MIRT795632	hsa-miR-125b	CLIP-seq
MIRT2174778	hsa-miR-143	CLIP-seq
MIRT795641	hsa-miR-1827	CLIP-seq
MIRT2174779	hsa-miR-188-5p	CLIP-seq
MIRT2174780	hsa-miR-200b	CLIP-seq
MIRT2174781	hsa-miR-200c	CLIP-seq
MIRT2174782	hsa-miR-2110	CLIP-seq
MIRT2174783	hsa-miR-2116	CLIP-seq
MIRT2174784	hsa-miR-2278	CLIP-seq
MIRT795648	hsa-miR-2467-3p	CLIP-seq
MIRT2174785	hsa-miR-300	CLIP-seq
MIRT795651	hsa-miR-3138	CLIP-seq
MIRT1934995	hsa-miR-3140-3p	CLIP-seq
MIRT2174786	hsa-miR-3150a-3p	CLIP-seq
MIRT2174787	hsa-miR-3175	CLIP-seq
MIRT2174788	hsa-miR-3192	CLIP-seq
MIRT1935001	hsa-miR-323b-3p	CLIP-seq
MIRT795657	hsa-miR-34b	CLIP-seq
MIRT795658	hsa-miR-3545-3p	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT795661	hsa-miR-3616-5p	CLIP-seq
MIRT795662	hsa-miR-3619-3p	CLIP-seq
MIRT795663	hsa-miR-3647-5p	CLIP-seq
MIRT2174789	hsa-miR-3665	CLIP-seq
MIRT2174790	hsa-miR-3682-5p	CLIP-seq
MIRT795668	hsa-miR-3689a-3p	CLIP-seq
MIRT795669	hsa-miR-3689c	CLIP-seq
MIRT2174791	hsa-miR-375	CLIP-seq
MIRT2174792	hsa-miR-381	CLIP-seq
MIRT795672	hsa-miR-3929	CLIP-seq
MIRT2174793	hsa-miR-3934	CLIP-seq
MIRT795674	hsa-miR-4257	CLIP-seq
MIRT2174794	hsa-miR-4266	CLIP-seq
MIRT2174795	hsa-miR-4269	CLIP-seq
MIRT2174796	hsa-miR-4273	CLIP-seq
MIRT2174797	hsa-miR-429	CLIP-seq
MIRT2174798	hsa-miR-4293	CLIP-seq
MIRT795677	hsa-miR-4318	CLIP-seq
MIRT795678	hsa-miR-4319	CLIP-seq
MIRT795680	hsa-miR-4419b	CLIP-seq
MIRT795681	hsa-miR-4420	CLIP-seq
MIRT2174799	hsa-miR-4468	CLIP-seq
MIRT795688	hsa-miR-4476	CLIP-seq
MIRT795690	hsa-miR-4478	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT2174800	hsa-miR-4639-5p	CLIP-seq
MIRT2174801	hsa-miR-4645-5p	CLIP-seq
MIRT795695	hsa-miR-4649-3p	CLIP-seq
MIRT2174802	hsa-miR-4666-3p	CLIP-seq
MIRT2174803	hsa-miR-4673	CLIP-seq
MIRT2174804	hsa-miR-4677-5p	CLIP-seq
MIRT1935018	hsa-miR-4691-5p	CLIP-seq
MIRT2174805	hsa-miR-4695-5p	CLIP-seq
MIRT795701	hsa-miR-4722-5p	CLIP-seq
MIRT795703	hsa-miR-4728-5p	CLIP-seq
MIRT795704	hsa-miR-4732-3p	CLIP-seq
MIRT1935022	hsa-miR-4738-3p	CLIP-seq
MIRT2174806	hsa-miR-4755-3p	CLIP-seq
MIRT2174807	hsa-miR-4756-3p	CLIP-seq
MIRT795712	hsa-miR-4768-3p	CLIP-seq
MIRT2174808	hsa-miR-4770	CLIP-seq
MIRT795715	hsa-miR-4776-5p	CLIP-seq
MIRT795717	hsa-miR-4778-5p	CLIP-seq
MIRT2174809	hsa-miR-4779	CLIP-seq
MIRT795720	hsa-miR-4795-5p	CLIP-seq
MIRT795722	hsa-miR-4800-5p	CLIP-seq
MIRT795723	hsa-miR-485-5p	CLIP-seq
MIRT795750	hsa-miR-573	CLIP-seq
MIRT2174810	hsa-miR-589	CLIP-seq
MIRT2174811	hsa-miR-596	CLIP-seq
MIRT1935030	hsa-miR-627	CLIP-seq
MIRT2174812	hsa-miR-661	CLIP-seq
MIRT795759	hsa-miR-670	CLIP-seq
MIRT2174813	hsa-miR-765	CLIP-seq
MIRT795760	hsa-miR-767-3p	CLIP-seq
MIRT2174814	hsa-miR-939	CLIP-seq
MIRT795762	hsa-miR-940	CLIP-seq
MIRT1934985	hsa-miR-1202	CLIP-seq
MIRT2174777	hsa-miR-1251	CLIP-seq
MIRT2443943	hsa-miR-1273	CLIP-seq
MIRT1934987	hsa-miR-137	CLIP-seq
MIRT2174782	hsa-miR-2110	CLIP-seq
MIRT2174786	hsa-miR-3150a-3p	CLIP-seq
MIRT2174787	hsa-miR-3175	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT1935007	hsa-miR-3972	CLIP-seq
MIRT2174798	hsa-miR-4293	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT2443944	hsa-miR-4517	CLIP-seq
MIRT2443945	hsa-miR-4649-5p	CLIP-seq
MIRT2174811	hsa-miR-596	CLIP-seq
MIRT2174812	hsa-miR-661	CLIP-seq
MIRT2174814	hsa-miR-939	CLIP-seq
MIRT2478163	hsa-miR-10a	CLIP-seq
MIRT2478164	hsa-miR-10b	CLIP-seq
MIRT795633	hsa-miR-1268	CLIP-seq
MIRT795634	hsa-miR-1268b	CLIP-seq
MIRT795635	hsa-miR-1272	CLIP-seq
MIRT2174782	hsa-miR-2110	CLIP-seq
MIRT2174786	hsa-miR-3150a-3p	CLIP-seq
MIRT2174787	hsa-miR-3175	CLIP-seq
MIRT2478165	hsa-miR-339-5p	CLIP-seq
MIRT795659	hsa-miR-3614-5p	CLIP-seq
MIRT795671	hsa-miR-3926	CLIP-seq
MIRT2478166	hsa-miR-4421	CLIP-seq
MIRT795691	hsa-miR-4486	CLIP-seq
MIRT2478167	hsa-miR-4684-5p	CLIP-seq
MIRT795718	hsa-miR-4786-5p	CLIP-seq
MIRT795719	hsa-miR-4793-5p	CLIP-seq
MIRT795742	hsa-miR-548n	CLIP-seq
MIRT795743	hsa-miR-548s	CLIP-seq
MIRT795748	hsa-miR-562	CLIP-seq
MIRT795751	hsa-miR-585	CLIP-seq
MIRT2478168	hsa-miR-593	CLIP-seq
MIRT2174814	hsa-miR-939	CLIP-seq
MIRT2478163	hsa-miR-10a	CLIP-seq
MIRT2478164	hsa-miR-10b	CLIP-seq
MIRT795635	hsa-miR-1272	CLIP-seq
MIRT2675316	hsa-miR-149	CLIP-seq
MIRT795647	hsa-miR-24	CLIP-seq
MIRT2478165	hsa-miR-339-5p	CLIP-seq
MIRT795671	hsa-miR-3926	CLIP-seq
MIRT795676	hsa-miR-4284	CLIP-seq
MIRT2675317	hsa-miR-4317	CLIP-seq
MIRT2478166	hsa-miR-4421	CLIP-seq
MIRT2478167	hsa-miR-4684-5p	CLIP-seq
MIRT795718	hsa-miR-4786-5p	CLIP-seq
MIRT795719	hsa-miR-4793-5p	CLIP-seq
MIRT2675318	hsa-miR-542-3p	CLIP-seq
MIRT795743	hsa-miR-548s	CLIP-seq
MIRT2478168	hsa-miR-593	CLIP-seq
MIRT2675319	hsa-miR-892b	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001726	Component	Ruffle	IEA
GO:0001886	Process	Endothelial cell morphogenesis	IEA
GO:0005829	Component	Cytosol	TAS
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS
GO:0043065	Process	Positive regulation of apoptotic process	TAS
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0090630	Process	Activation of GTPase activity	IBA	21873635
GO:0097178	Process	Ruffle assembly	IEA

MIM	HGNC	e!Ensembl
617552	24490	ENSG00000114790

Protein

UniProt ID

Q96DR7

Protein name

Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)

Protein function

Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of

PDB

6MYE , 7YKG

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00621	RhoGEF	443 → 621	RhoGEF domain	Domain
PF00018	SH3_1	799 → 842	SH3 domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Isoform 1 is broadly expressed, with highest levels in liver (at protein level). Certain mRNA species appear to be specifically expressed in prostate and liver. {ECO:0000269|PubMed:12697679, ECO:0000269|PubMed:15133129}.

Sequence

MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLL
AAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAV
PGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAA
NNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSP
AALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDN
DVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRI
KKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQ
LSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTER
HHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQ
RTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDS
PKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRG
ELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNE
ELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHS
SGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWF
PMECAKEITCQATIDKNVERMGRLLGLETNV

Sequence length

871

Interactions

View interactions

	KEGG		Reactome
	Bacterial invasion of epithelial cells Salmonella infection		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Coronary artery disease	Coronary Artery Disease	rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537	28714974, 29212778, 28714975
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	26198764

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Evidence	Source
Unknown
Myocardial Infarction	Myocardial Infarction		GWAS
Psoriasis	Psoriasis		GWAS
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.	GWAS, CBGDA

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	29454349, 34558724
Breast Neoplasms	Associate	28202690
Carcinoma Squamous Cell	Associate	34301206
Cholangiocarcinoma	Associate	31886187
Colorectal Neoplasms	Associate	31159706
Coronary Artery Disease	Associate	28584231
Esophageal Neoplasms	Associate	35003396
Esophageal Squamous Cell Carcinoma	Associate	35003396
Glioblastoma	Stimulate	23775076, 26764186
Glioma	Associate	23775076, 26764186, 29454349
Leigh syndrome French Canadian type	Associate	29454349
Neoplasms	Associate	29454349
Osteoarthritis	Associate	37378023
Prostatic Neoplasms	Associate	29454349
Vascular Diseases	Associate	36928188

ARHGEF26 (Rho guanine nucleotide exchange factor 26)