Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26056
Gene name Gene Name - the full gene name approved by the HGNC.
RAB11 family interacting protein 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RAB11FIP5
Synonyms (NCBI Gene) Gene synonyms aliases
GAF1, RIP11, gaf-1, pp75, rab11-FIP5
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p13.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022567 hsa-miR-124-3p Microarray 18668037
MIRT025784 hsa-miR-7-5p Microarray 19073608
MIRT504801 hsa-miR-8485 PAR-CLIP 22012620
MIRT504800 hsa-miR-6760-3p PAR-CLIP 22012620
MIRT504799 hsa-miR-6776-3p PAR-CLIP 22012620
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005515 Function Protein binding IPI 11278501, 12470645, 24591568, 26496610, 28514442, 29568061
GO:0005739 Component Mitochondrion IBA 21873635
GO:0005741 Component Mitochondrial outer membrane IDA 11278501
GO:0005769 Component Early endosome IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
605536 24845 ENSG00000135631
Protein
UniProt ID Q9BXF6
Protein name Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Protein function Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis. {ECO:0000269
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00168 C2 19 148 C2 domain Domain
PF09457 RBD-FIP 601 648 FIP domain Motif
Tissue specificity TISSUE SPECIFICITY: Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas. {ECO:0000269|PubMed:10545525, ECO:0000269|PubMed:11278501}.
Sequence
MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVV
EKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGV
DKFLGQATVALDEVFGAGRAQHTQWYKL
HSKPGKKEKERGEIEVTIQFTRNNLSASMFDL
SMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKL
RKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLF
THKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISG
SLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHP
GEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRR
SSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPD
RKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHL
THDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK
Sequence length 653
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Endocytosis  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Autism Autistic Disorder rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699
View all (8 more)
18384058
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
31374203
Associations from Text Mining
Disease Name Relationship Type References
Autism Spectrum Disorder Associate 18384058
Colorectal Neoplasms Associate 29547645
HIV Infections Associate 30270043
Lymphoma Large B Cell Diffuse Associate 27835906
Prostatic Neoplasms Associate 29759989
Virus Diseases Associate 40296166