MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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260425 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Membrane associated guanylate kinase, WW and PDZ domain containing 3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MAGI3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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MAGI-3, dJ730K3.2 |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p13.2 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||||||||||||
| UniProt ID | Q5TCQ9 | ||||||||||||||||||||||||||||||||||||||||
| Protein name | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3) | ||||||||||||||||||||||||||||||||||||||||
| Protein function | Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins sugg | ||||||||||||||||||||||||||||||||||||||||
| PDB | 3SOE | ||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10748157}. | ||||||||||||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 1481 | ||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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