Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	26034
Gene name Gene Name - the full gene name approved by the HGNC.	Interaction protein for cytohesin exchange factors 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	IPCEF1
Synonyms (NCBI Gene) Gene synonyms aliases	PIP3-E, PIP3E
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q25.2

Show/Hide all(238)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022415	hsa-miR-124-3p	Microarray	18668037
MIRT052329	hsa-let-7b-5p	CLASH	23622248
MIRT047560	hsa-miR-10a-5p	CLASH	23622248
MIRT047416	hsa-miR-10b-5p	CLASH	23622248
MIRT667868	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT667867	hsa-miR-6753-5p	HITS-CLIP	23824327
MIRT667866	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667865	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667864	hsa-miR-940	HITS-CLIP	23824327
MIRT667863	hsa-miR-3929	HITS-CLIP	23824327
MIRT667862	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667861	hsa-miR-4478	HITS-CLIP	23824327
MIRT667860	hsa-miR-1321	HITS-CLIP	23824327
MIRT667859	hsa-miR-4739	HITS-CLIP	23824327
MIRT667858	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT667857	hsa-miR-5690	HITS-CLIP	23824327
MIRT667856	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667855	hsa-miR-4270	HITS-CLIP	23824327
MIRT667854	hsa-miR-4441	HITS-CLIP	23824327
MIRT667853	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT667852	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT667851	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT667850	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT667849	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT667848	hsa-miR-1827	HITS-CLIP	23824327
MIRT667847	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667846	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT667845	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT667844	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT667843	hsa-miR-3612	HITS-CLIP	23824327
MIRT667842	hsa-miR-650	HITS-CLIP	23824327
MIRT667841	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT667840	hsa-miR-665	HITS-CLIP	23824327
MIRT623612	hsa-miR-5582-5p	HITS-CLIP	23824327
MIRT623611	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT623610	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT623609	hsa-miR-8064	HITS-CLIP	23824327
MIRT623608	hsa-miR-664b-5p	HITS-CLIP	23824327
MIRT623607	hsa-miR-623	HITS-CLIP	23824327
MIRT623606	hsa-miR-4674	HITS-CLIP	23824327
MIRT623605	hsa-miR-1587	HITS-CLIP	23824327
MIRT623603	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT623604	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT623602	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT623601	hsa-miR-521	HITS-CLIP	23824327
MIRT667868	hsa-miR-34b-3p	HITS-CLIP	23824327
MIRT667867	hsa-miR-6753-5p	HITS-CLIP	23824327
MIRT667866	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667865	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667864	hsa-miR-940	HITS-CLIP	23824327
MIRT667863	hsa-miR-3929	HITS-CLIP	23824327
MIRT667862	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667861	hsa-miR-4478	HITS-CLIP	23824327
MIRT667860	hsa-miR-1321	HITS-CLIP	23824327
MIRT667859	hsa-miR-4739	HITS-CLIP	23824327
MIRT667858	hsa-miR-4756-5p	HITS-CLIP	23824327
MIRT667857	hsa-miR-5690	HITS-CLIP	23824327
MIRT667856	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667855	hsa-miR-4270	HITS-CLIP	23824327
MIRT667854	hsa-miR-4441	HITS-CLIP	23824327
MIRT667853	hsa-miR-6754-5p	HITS-CLIP	23824327
MIRT667852	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT667851	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT667850	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT667849	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT667848	hsa-miR-1827	HITS-CLIP	23824327
MIRT667847	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667846	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT667845	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT667844	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT667843	hsa-miR-3612	HITS-CLIP	23824327
MIRT667842	hsa-miR-650	HITS-CLIP	23824327
MIRT667841	hsa-miR-6771-5p	HITS-CLIP	23824327
MIRT667840	hsa-miR-665	HITS-CLIP	23824327
MIRT623612	hsa-miR-5582-5p	HITS-CLIP	23824327
MIRT623611	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT623610	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT623609	hsa-miR-8064	HITS-CLIP	23824327
MIRT623608	hsa-miR-664b-5p	HITS-CLIP	23824327
MIRT623607	hsa-miR-623	HITS-CLIP	23824327
MIRT623606	hsa-miR-4674	HITS-CLIP	23824327
MIRT623605	hsa-miR-1587	HITS-CLIP	23824327
MIRT623603	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT623604	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT623602	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT623601	hsa-miR-521	HITS-CLIP	23824327
MIRT1068445	hsa-miR-1228	CLIP-seq
MIRT1068446	hsa-miR-1279	CLIP-seq
MIRT1068447	hsa-miR-1281	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT1068449	hsa-miR-150	CLIP-seq
MIRT1068450	hsa-miR-205	CLIP-seq
MIRT1068451	hsa-miR-24	CLIP-seq
MIRT1068452	hsa-miR-2467-3p	CLIP-seq
MIRT1068453	hsa-miR-3120-5p	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068455	hsa-miR-3192	CLIP-seq
MIRT1068456	hsa-miR-326	CLIP-seq
MIRT1068457	hsa-miR-330-5p	CLIP-seq
MIRT1068458	hsa-miR-342-3p	CLIP-seq
MIRT1068459	hsa-miR-3613-5p	CLIP-seq
MIRT1068460	hsa-miR-3664-5p	CLIP-seq
MIRT1068461	hsa-miR-3689a-3p	CLIP-seq
MIRT1068462	hsa-miR-3689c	CLIP-seq
MIRT1068463	hsa-miR-3934	CLIP-seq
MIRT1068464	hsa-miR-4261	CLIP-seq
MIRT1068465	hsa-miR-4284	CLIP-seq
MIRT1068466	hsa-miR-4314	CLIP-seq
MIRT1068467	hsa-miR-4421	CLIP-seq
MIRT1068468	hsa-miR-4432	CLIP-seq
MIRT1068469	hsa-miR-4496	CLIP-seq
MIRT1068470	hsa-miR-451b	CLIP-seq
MIRT1068471	hsa-miR-4522	CLIP-seq
MIRT1068472	hsa-miR-4646-5p	CLIP-seq
MIRT1068473	hsa-miR-4665-3p	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT1068475	hsa-miR-4696	CLIP-seq
MIRT1068476	hsa-miR-4713-5p	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT1068478	hsa-miR-4753-3p	CLIP-seq
MIRT1068479	hsa-miR-4768-5p	CLIP-seq
MIRT1068480	hsa-miR-4796-5p	CLIP-seq
MIRT1068481	hsa-miR-483-3p	CLIP-seq
MIRT1068482	hsa-miR-494	CLIP-seq
MIRT1068483	hsa-miR-532-3p	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT1068486	hsa-miR-204	CLIP-seq
MIRT1068487	hsa-miR-211	CLIP-seq
MIRT1068488	hsa-miR-2277-3p	CLIP-seq
MIRT1068452	hsa-miR-2467-3p	CLIP-seq
MIRT1068489	hsa-miR-3122	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068490	hsa-miR-3613-3p	CLIP-seq
MIRT1068491	hsa-miR-3622a-3p	CLIP-seq
MIRT1068492	hsa-miR-3622b-3p	CLIP-seq
MIRT1068493	hsa-miR-371b-5p	CLIP-seq
MIRT1068494	hsa-miR-377	CLIP-seq
MIRT1068495	hsa-miR-3913-5p	CLIP-seq
MIRT1068496	hsa-miR-3923	CLIP-seq
MIRT1068497	hsa-miR-3926	CLIP-seq
MIRT1068498	hsa-miR-4257	CLIP-seq
MIRT1068499	hsa-miR-4328	CLIP-seq
MIRT1068500	hsa-miR-4433	CLIP-seq
MIRT1068501	hsa-miR-4446-5p	CLIP-seq
MIRT1068502	hsa-miR-4459	CLIP-seq
MIRT1068503	hsa-miR-4640-5p	CLIP-seq
MIRT1068504	hsa-miR-4704-5p	CLIP-seq
MIRT1068505	hsa-miR-4726-5p	CLIP-seq
MIRT1068506	hsa-miR-4731-5p	CLIP-seq
MIRT1068507	hsa-miR-4778-3p	CLIP-seq
MIRT1068508	hsa-miR-514	CLIP-seq
MIRT1068509	hsa-miR-514b-3p	CLIP-seq
MIRT1068510	hsa-miR-544b	CLIP-seq
MIRT1068511	hsa-miR-587	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT1068512	hsa-miR-628-3p	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT2248780	hsa-miR-1179	CLIP-seq
MIRT2248781	hsa-miR-4324	CLIP-seq
MIRT1068510	hsa-miR-544b	CLIP-seq
MIRT2451896	hsa-miR-3163	CLIP-seq
MIRT2451897	hsa-miR-3675-5p	CLIP-seq
MIRT2451898	hsa-miR-4656	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT2451899	hsa-miR-486-3p	CLIP-seq
MIRT2451900	hsa-miR-548c-3p	CLIP-seq
MIRT2451901	hsa-miR-585	CLIP-seq
MIRT2451902	hsa-miR-885-3p	CLIP-seq
MIRT2451897	hsa-miR-3675-5p	CLIP-seq
MIRT2451898	hsa-miR-4656	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT2451899	hsa-miR-486-3p	CLIP-seq
MIRT2451902	hsa-miR-885-3p	CLIP-seq
MIRT1068445	hsa-miR-1228	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT2552526	hsa-miR-2114	CLIP-seq
MIRT1068452	hsa-miR-2467-3p	CLIP-seq
MIRT1068453	hsa-miR-3120-5p	CLIP-seq
MIRT2451896	hsa-miR-3163	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068455	hsa-miR-3192	CLIP-seq
MIRT1068456	hsa-miR-326	CLIP-seq
MIRT1068457	hsa-miR-330-5p	CLIP-seq
MIRT1068491	hsa-miR-3622a-3p	CLIP-seq
MIRT1068492	hsa-miR-3622b-3p	CLIP-seq
MIRT1068460	hsa-miR-3664-5p	CLIP-seq
MIRT1068461	hsa-miR-3689a-3p	CLIP-seq
MIRT1068462	hsa-miR-3689c	CLIP-seq
MIRT1068494	hsa-miR-377	CLIP-seq
MIRT2552527	hsa-miR-3924	CLIP-seq
MIRT2552528	hsa-miR-4252	CLIP-seq
MIRT1068466	hsa-miR-4314	CLIP-seq
MIRT1068468	hsa-miR-4432	CLIP-seq
MIRT1068500	hsa-miR-4433	CLIP-seq
MIRT1068502	hsa-miR-4459	CLIP-seq
MIRT2552529	hsa-miR-4514	CLIP-seq
MIRT1068470	hsa-miR-451b	CLIP-seq
MIRT1068471	hsa-miR-4522	CLIP-seq
MIRT1068472	hsa-miR-4646-5p	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT2552530	hsa-miR-4692	CLIP-seq
MIRT1068475	hsa-miR-4696	CLIP-seq
MIRT1068477	hsa-miR-4728-5p	CLIP-seq
MIRT2552531	hsa-miR-4793-3p	CLIP-seq
MIRT2552532	hsa-miR-508-5p	CLIP-seq
MIRT1068510	hsa-miR-544b	CLIP-seq
MIRT2451900	hsa-miR-548c-3p	CLIP-seq
MIRT2552533	hsa-miR-561	CLIP-seq
MIRT2451901	hsa-miR-585	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT2552534	hsa-miR-633	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT2552535	hsa-miR-766	CLIP-seq
MIRT2682868	hsa-miR-1227	CLIP-seq
MIRT1068448	hsa-miR-1285	CLIP-seq
MIRT2552526	hsa-miR-2114	CLIP-seq
MIRT1068453	hsa-miR-3120-5p	CLIP-seq
MIRT2451896	hsa-miR-3163	CLIP-seq
MIRT1068454	hsa-miR-3187-5p	CLIP-seq
MIRT1068460	hsa-miR-3664-5p	CLIP-seq
MIRT2552528	hsa-miR-4252	CLIP-seq
MIRT1068468	hsa-miR-4432	CLIP-seq
MIRT1068470	hsa-miR-451b	CLIP-seq
MIRT1068471	hsa-miR-4522	CLIP-seq
MIRT1068474	hsa-miR-4684-5p	CLIP-seq
MIRT1068475	hsa-miR-4696	CLIP-seq
MIRT2552531	hsa-miR-4793-3p	CLIP-seq
MIRT2552532	hsa-miR-508-5p	CLIP-seq
MIRT2451900	hsa-miR-548c-3p	CLIP-seq
MIRT2552533	hsa-miR-561	CLIP-seq
MIRT2451901	hsa-miR-585	CLIP-seq
MIRT1068484	hsa-miR-612	CLIP-seq
MIRT2552534	hsa-miR-633	CLIP-seq
MIRT1068485	hsa-miR-661	CLIP-seq
MIRT2552535	hsa-miR-766	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004601	Function	Peroxidase activity	ISS	11320098
GO:0005344	Function	Oxygen carrier activity	NAS	11919282
GO:0005515	Function	Protein binding	IPI	22085542, 32296183
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006979	Process	Response to oxidative stress	ISS	11320098
GO:0015671	Process	Oxygen transport	NAS	11919282
GO:0019904	Function	Protein domain specific binding	IEA
GO:0098869	Process	Cellular oxidant detoxification	IEA

MIM	HGNC	e!Ensembl
619948	21204	ENSG00000074706

Protein

UniProt ID

Q8WWN9

Protein name

Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)

Protein function

Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner.

PDB

5MR1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00169	PH	42 → 139	PH domain	Domain

Sequence

MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRRISCKDLGHADCQGWLYKKKEKGSFLSN
KWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKISHPQIKTFYF
AAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTA
QQASSSSPSLSGTSYSFSSLENTVKTPSSFPSSLSKERQSLPDTVNSLSAAEDEGQPITF
AVQVHSPVPSEAGIHKALENSFVTSESGFLNSLSSDDTSSLSSNHDHLTVPDKPAGSKIM
DKEETKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIR
TLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQRASPAPDDTDDT
PQELKKSPSSPSVENSI

Sequence length

437

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Dermatitis	Dermatitis, Allergic Contact	rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174	17374397

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Source
Unknown
Asthma	Asthma	GWAS
Lymphocytic Leukemia	Lymphocytic Leukemia	GWAS
Diabetes	Diabetes	GWAS
Systemic lupus erythematosus	Systemic lupus erythematosus	GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Diabetic Nephropathies	Associate	34545296
Drug Hypersensitivity	Associate	29679657
Sarcoma	Associate	35143416
Thyroid Cancer Papillary	Associate	36465624

IPCEF1 (interaction protein for cytohesin exchange factors 1)