Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
26009
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger ZZ-type containing 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZZZ3
Synonyms (NCBI Gene) Gene synonyms aliases
ATAC1
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p31.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT665235 hsa-miR-495-3p HITS-CLIP 23824327
MIRT665234 hsa-miR-5688 HITS-CLIP 23824327
MIRT665233 hsa-miR-767-3p HITS-CLIP 23824327
MIRT665232 hsa-miR-3182 HITS-CLIP 23824327
MIRT665231 hsa-miR-548aj-5p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 20562830, 23088713, 24981860, 25416956, 27705803, 32296183
GO:0005654 Component Nucleoplasm IDA
GO:0005671 Component Ada2/Gcn5/Ada3 transcription activator complex IBA 21873635
GO:0005730 Component Nucleolus IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
619892 24523 ENSG00000036549
Protein
UniProt ID Q8IYH5
Protein name ZZ-type zinc finger-containing protein 3
Protein function Histone H3 reader that is required for the ATAC complex-mediated maintenance of histone acetylation and gene activation (PubMed:30217978). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (Pu
PDB 2FC7 , 2YUM , 6E83 , 6E86
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00249 Myb_DNA-binding 652 703 Myb-like DNA-binding domain Domain
PF00569 ZZ 817 865 Zinc finger, ZZ type Domain
Sequence
MAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSNSQVRSRSPKKRPEPVPIQ
KGNNNGRTTDLKQQSTRESWVSPRKRGLSSSEKDNIERQAIENCERRQTEPVSPVLKRIK
RCLRSEAPNSSEEDSPIKSDKESVEQRSTVVDNDADFQGTKRACRCLILDDCEKREIKKV
NVSEEGPLNSAVVEEITGYLAVNGVDDSDSAVINCDDCQPDGNTKQNSIGSYVLQEKSVA
ENGDTDTQTSMFLDSRKEDSYIDHKVPCTDSQVQVKLEDHKIVTACLPVEHVNQLTTEPA
TGPFSETQSSLRDSEEEVDVVGDSSASKEQCKENTNNELDTSLESMPASGEPEPSPVLDC
VSAQMMSLSEPQEHRYTLRTSPRRAAPTRGSPTKNSSPYRENGQFEENNLSPNETNATVS
DNVSQSPTNPGEISQNEKGICCDSQNNGSEGVSKPPSEARLNIGHLPSAKESASQHITEE
EDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGRHQREALKNPIG
FVEKLQKKADIGLPYPQRVVQLPEIVWDQYTHSLGNFEREFKNRKRHTRRVKLVFDKVGL
PARPKSPLDPKKDGESLSYSMLPLSDGPEGSSSRPQMIRGRLCDDTKPETFNQLWTVEEQ
KKLEQLLIKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYF
IKLTKAGIPVPGRTPNL
YIYSKKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCFHSHMNTAVEDASDDE
SIPIMYRNLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGIEPIQGVRWHCQD
CPPEMSLDFCDSCSDCLHETDIHKE
DHQLEPIYRSETFLDRDYCVSQGTSYNYLDPNYFP
ANR
Sequence length 903
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
Unknown
Disease term Disease name Evidence References Source
Obesity Obesity GWAS
Lung adenocarcinoma Lung adenocarcinoma Validation that loss of Tgfbr2 results in more aggressive and T cell-excluded KP lung tumors GWAS, CBGDA
Insomnia Insomnia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Diabetes Mellitus Type 2 Associate 26282996
Lymphoma Large B Cell Diffuse Associate 39376717
Obesity Associate 23563607