Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	25992
Gene name	Sushi, nidogen and EGF like domains 1
Gene symbol	SNED1
Synonyms (NCBI Gene)	IRE-BP1SST3Snep
Chromosome	2
Chromosome location	2q37.3

199

Show/Hide all (199)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016924	hsa-miR-335-5p	Microarray	18185580
MIRT714433	hsa-miR-4753-5p	HITS-CLIP	19536157
MIRT714432	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT714431	hsa-miR-135a-5p	HITS-CLIP	19536157
MIRT714430	hsa-miR-135b-5p	HITS-CLIP	19536157
MIRT714429	hsa-miR-103a-2-5p	HITS-CLIP	19536157
MIRT714428	hsa-miR-6815-3p	HITS-CLIP	19536157
MIRT714427	hsa-miR-124-3p	HITS-CLIP	19536157
MIRT714426	hsa-miR-506-3p	HITS-CLIP	19536157
MIRT714425	hsa-miR-4775	HITS-CLIP	19536157
MIRT714424	hsa-miR-5011-3p	HITS-CLIP	19536157
MIRT714423	hsa-miR-4666b	HITS-CLIP	19536157
MIRT714422	hsa-miR-450b-5p	HITS-CLIP	19536157
MIRT714421	hsa-miR-507	HITS-CLIP	19536157
MIRT714420	hsa-miR-557	HITS-CLIP	19536157
MIRT714419	hsa-miR-3680-3p	HITS-CLIP	19536157
MIRT714433	hsa-miR-4753-5p	HITS-CLIP	19536157
MIRT714432	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT714431	hsa-miR-135a-5p	HITS-CLIP	19536157
MIRT714430	hsa-miR-135b-5p	HITS-CLIP	19536157
MIRT714429	hsa-miR-103a-2-5p	HITS-CLIP	19536157
MIRT714428	hsa-miR-6815-3p	HITS-CLIP	19536157
MIRT714427	hsa-miR-124-3p	HITS-CLIP	19536157
MIRT714426	hsa-miR-506-3p	HITS-CLIP	19536157
MIRT714425	hsa-miR-4775	HITS-CLIP	19536157
MIRT714424	hsa-miR-5011-3p	HITS-CLIP	19536157
MIRT714423	hsa-miR-4666b	HITS-CLIP	19536157
MIRT714422	hsa-miR-450b-5p	HITS-CLIP	19536157
MIRT714421	hsa-miR-507	HITS-CLIP	19536157
MIRT714420	hsa-miR-557	HITS-CLIP	19536157
MIRT714419	hsa-miR-3680-3p	HITS-CLIP	19536157
MIRT1375455	hsa-miR-145	CLIP-seq
MIRT1375456	hsa-miR-1909	CLIP-seq
MIRT1375457	hsa-miR-2276	CLIP-seq
MIRT1375458	hsa-miR-2278	CLIP-seq
MIRT1375459	hsa-miR-3180	CLIP-seq
MIRT1375460	hsa-miR-3180-3p	CLIP-seq
MIRT1375461	hsa-miR-3196	CLIP-seq
MIRT1375462	hsa-miR-346	CLIP-seq
MIRT1375463	hsa-miR-3613-3p	CLIP-seq
MIRT1375464	hsa-miR-3684	CLIP-seq
MIRT1375465	hsa-miR-4288	CLIP-seq
MIRT1375466	hsa-miR-4328	CLIP-seq
MIRT1375467	hsa-miR-4426	CLIP-seq
MIRT1375468	hsa-miR-452	CLIP-seq
MIRT1375469	hsa-miR-4647	CLIP-seq
MIRT1375470	hsa-miR-4662b	CLIP-seq
MIRT1375471	hsa-miR-4676-3p	CLIP-seq
MIRT1375472	hsa-miR-4711-3p	CLIP-seq
MIRT1375473	hsa-miR-4772-3p	CLIP-seq
MIRT1375474	hsa-miR-520d-5p	CLIP-seq
MIRT1375475	hsa-miR-524-5p	CLIP-seq
MIRT1375476	hsa-miR-618	CLIP-seq
MIRT1375477	hsa-miR-632	CLIP-seq
MIRT2111642	hsa-miR-2277-3p	CLIP-seq
MIRT2111643	hsa-miR-4271	CLIP-seq
MIRT2111644	hsa-miR-4420	CLIP-seq
MIRT1375468	hsa-miR-452	CLIP-seq
MIRT1375471	hsa-miR-4676-3p	CLIP-seq
MIRT2111645	hsa-miR-4725-3p	CLIP-seq
MIRT2334819	hsa-miR-1184	CLIP-seq
MIRT2334820	hsa-miR-1262	CLIP-seq
MIRT2334821	hsa-miR-1301	CLIP-seq
MIRT2334822	hsa-miR-3199	CLIP-seq
MIRT2334823	hsa-miR-345	CLIP-seq
MIRT2334824	hsa-miR-3591-5p	CLIP-seq
MIRT2334825	hsa-miR-3647-3p	CLIP-seq
MIRT2334826	hsa-miR-4255	CLIP-seq
MIRT2334827	hsa-miR-4453	CLIP-seq
MIRT2334828	hsa-miR-4513	CLIP-seq
MIRT2334829	hsa-miR-4538	CLIP-seq
MIRT2334830	hsa-miR-4539	CLIP-seq
MIRT2334831	hsa-miR-4652-5p	CLIP-seq
MIRT2334832	hsa-miR-4660	CLIP-seq
MIRT2334833	hsa-miR-4680-5p	CLIP-seq
MIRT2334834	hsa-miR-4701-3p	CLIP-seq
MIRT2334835	hsa-miR-4733-3p	CLIP-seq
MIRT2334836	hsa-miR-4740-5p	CLIP-seq
MIRT2334837	hsa-miR-5047	CLIP-seq
MIRT2334838	hsa-miR-508-5p	CLIP-seq
MIRT2460102	hsa-miR-1179	CLIP-seq
MIRT2460103	hsa-miR-141	CLIP-seq
MIRT2460104	hsa-miR-147	CLIP-seq
MIRT2460105	hsa-miR-200a	CLIP-seq
MIRT2460106	hsa-miR-3688-5p	CLIP-seq
MIRT2460107	hsa-miR-3911	CLIP-seq
MIRT2460108	hsa-miR-4263	CLIP-seq
MIRT2460109	hsa-miR-4457	CLIP-seq
MIRT2460110	hsa-miR-4731-3p	CLIP-seq
MIRT2460111	hsa-miR-4801	CLIP-seq
MIRT2460112	hsa-miR-642b	CLIP-seq
MIRT2460113	hsa-miR-644	CLIP-seq
MIRT2334819	hsa-miR-1184	CLIP-seq
MIRT2628972	hsa-miR-1204	CLIP-seq
MIRT2334820	hsa-miR-1262	CLIP-seq
MIRT2334821	hsa-miR-1301	CLIP-seq
MIRT2628973	hsa-miR-1913	CLIP-seq
MIRT2628974	hsa-miR-3157-5p	CLIP-seq
MIRT2628975	hsa-miR-3186-5p	CLIP-seq
MIRT2628976	hsa-miR-3187-3p	CLIP-seq
MIRT2628977	hsa-miR-324-3p	CLIP-seq
MIRT2628978	hsa-miR-34a	CLIP-seq
MIRT2628979	hsa-miR-34c-5p	CLIP-seq
MIRT2628980	hsa-miR-3616-3p	CLIP-seq
MIRT2628981	hsa-miR-3650	CLIP-seq
MIRT2628982	hsa-miR-3672	CLIP-seq
MIRT2628983	hsa-miR-3677-3p	CLIP-seq
MIRT2628984	hsa-miR-4302	CLIP-seq
MIRT2628985	hsa-miR-4313	CLIP-seq
MIRT2628986	hsa-miR-4438	CLIP-seq
MIRT2334827	hsa-miR-4453	CLIP-seq
MIRT2628987	hsa-miR-449a	CLIP-seq
MIRT2628988	hsa-miR-449b	CLIP-seq
MIRT2628989	hsa-miR-4529-5p	CLIP-seq
MIRT2334829	hsa-miR-4538	CLIP-seq
MIRT2628990	hsa-miR-4650-5p	CLIP-seq
MIRT2334832	hsa-miR-4660	CLIP-seq
MIRT2628991	hsa-miR-4690-3p	CLIP-seq
MIRT2334834	hsa-miR-4701-3p	CLIP-seq
MIRT2628992	hsa-miR-4710	CLIP-seq
MIRT2628993	hsa-miR-4721	CLIP-seq
MIRT2628994	hsa-miR-502-5p	CLIP-seq
MIRT2334837	hsa-miR-5047	CLIP-seq
MIRT2628995	hsa-miR-524-3p	CLIP-seq
MIRT2628996	hsa-miR-525-3p	CLIP-seq
MIRT2628997	hsa-miR-550a	CLIP-seq
MIRT2628998	hsa-miR-648	CLIP-seq
MIRT2628999	hsa-miR-938	CLIP-seq
MIRT2460102	hsa-miR-1179	CLIP-seq
MIRT2334819	hsa-miR-1184	CLIP-seq
MIRT2628972	hsa-miR-1204	CLIP-seq
MIRT2334820	hsa-miR-1262	CLIP-seq
MIRT2691626	hsa-miR-1266	CLIP-seq
MIRT2691627	hsa-miR-1273g	CLIP-seq
MIRT2334821	hsa-miR-1301	CLIP-seq
MIRT2691628	hsa-miR-133a	CLIP-seq
MIRT2691629	hsa-miR-133b	CLIP-seq
MIRT2460103	hsa-miR-141	CLIP-seq
MIRT2460104	hsa-miR-147	CLIP-seq
MIRT1375456	hsa-miR-1909	CLIP-seq
MIRT2691630	hsa-miR-1912	CLIP-seq
MIRT2460105	hsa-miR-200a	CLIP-seq
MIRT2691631	hsa-miR-3127-5p	CLIP-seq
MIRT2691632	hsa-miR-3130-5p	CLIP-seq
MIRT2628975	hsa-miR-3186-5p	CLIP-seq
MIRT2628976	hsa-miR-3187-3p	CLIP-seq
MIRT2628978	hsa-miR-34a	CLIP-seq
MIRT2628979	hsa-miR-34c-5p	CLIP-seq
MIRT2691633	hsa-miR-3613-5p	CLIP-seq
MIRT2628980	hsa-miR-3616-3p	CLIP-seq
MIRT2334825	hsa-miR-3647-3p	CLIP-seq
MIRT2628981	hsa-miR-3650	CLIP-seq
MIRT2691634	hsa-miR-3664-3p	CLIP-seq
MIRT2628982	hsa-miR-3672	CLIP-seq
MIRT2628983	hsa-miR-3677-3p	CLIP-seq
MIRT2460107	hsa-miR-3911	CLIP-seq
MIRT2691635	hsa-miR-3929	CLIP-seq
MIRT2460108	hsa-miR-4263	CLIP-seq
MIRT2691636	hsa-miR-4267	CLIP-seq
MIRT2691637	hsa-miR-4281	CLIP-seq
MIRT2628984	hsa-miR-4302	CLIP-seq
MIRT2691638	hsa-miR-4419b	CLIP-seq
MIRT2691639	hsa-miR-4427	CLIP-seq
MIRT2628986	hsa-miR-4438	CLIP-seq
MIRT2334827	hsa-miR-4453	CLIP-seq
MIRT2460109	hsa-miR-4457	CLIP-seq
MIRT2691640	hsa-miR-4478	CLIP-seq
MIRT2691641	hsa-miR-4482	CLIP-seq
MIRT2628987	hsa-miR-449a	CLIP-seq
MIRT2628988	hsa-miR-449b	CLIP-seq
MIRT2691642	hsa-miR-4518	CLIP-seq
MIRT2628989	hsa-miR-4529-5p	CLIP-seq
MIRT2334829	hsa-miR-4538	CLIP-seq
MIRT2628990	hsa-miR-4650-5p	CLIP-seq
MIRT2334832	hsa-miR-4660	CLIP-seq
MIRT2691643	hsa-miR-4680-3p	CLIP-seq
MIRT2691644	hsa-miR-4687-3p	CLIP-seq
MIRT2334834	hsa-miR-4701-3p	CLIP-seq
MIRT2628992	hsa-miR-4710	CLIP-seq
MIRT2691645	hsa-miR-4715-3p	CLIP-seq
MIRT2628993	hsa-miR-4721	CLIP-seq
MIRT2460110	hsa-miR-4731-3p	CLIP-seq
MIRT2691646	hsa-miR-4759	CLIP-seq
MIRT2460111	hsa-miR-4801	CLIP-seq
MIRT2628994	hsa-miR-502-5p	CLIP-seq
MIRT2334837	hsa-miR-5047	CLIP-seq
MIRT2334838	hsa-miR-508-5p	CLIP-seq
MIRT2691647	hsa-miR-513a-5p	CLIP-seq
MIRT2628995	hsa-miR-524-3p	CLIP-seq
MIRT2628996	hsa-miR-525-3p	CLIP-seq
MIRT2628997	hsa-miR-550a	CLIP-seq
MIRT2691648	hsa-miR-552	CLIP-seq
MIRT2691649	hsa-miR-587	CLIP-seq
MIRT2460112	hsa-miR-642b	CLIP-seq
MIRT2460113	hsa-miR-644	CLIP-seq
MIRT2691650	hsa-miR-645	CLIP-seq
MIRT2628998	hsa-miR-648	CLIP-seq
MIRT2691651	hsa-miR-766	CLIP-seq
MIRT2691652	hsa-miR-876-3p	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005112	Function	Notch binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0007160	Process	Cell-matrix adhesion	IEA
GO:0031012	Component	Extracellular matrix	IDA	33724335
GO:0031012	Component	Extracellular matrix	IEA

MIM	HGNC	e!Ensembl
616634	24696	ENSG00000162804

Q8TER0

Protein name

Sushi, nidogen and EGF-like domain-containing protein 1 (Insulin-responsive sequence DNA-binding protein 1) (IRE-BP1)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06119	NIDO	168 → 257	Nidogen-like	Family
PF00008	EGF	272 → 307	EGF-like domain	Domain
PF00008	EGF	315 → 345	EGF-like domain	Domain
PF12661	hEGF	358 → 379	Human growth factor-like EGF	Domain
PF00008	EGF	391 → 421	EGF-like domain	Domain
PF00008	EGF	433 → 463	EGF-like domain	Domain
PF12661	hEGF	474 → 494	Human growth factor-like EGF	Domain
PF00008	EGF	545 → 575	EGF-like domain	Domain
PF00008	EGF	584 → 614	EGF-like domain	Domain
PF00008	EGF	623 → 653	EGF-like domain	Domain
PF12661	hEGF	666 → 687	Human growth factor-like EGF	Domain
PF00008	EGF	757 → 787	EGF-like domain	Domain
PF00008	EGF	795 → 825	EGF-like domain	Domain
PF00008	EGF	833 → 863	EGF-like domain	Domain
PF00041	fn3	908 → 991	Fibronectin type III domain	Domain
PF00041	fn3	1005 → 1088	Fibronectin type III domain	Domain
PF00041	fn3	1105 → 1186	Fibronectin type III domain	Domain
PF00008	EGF	1311 → 1341	EGF-like domain	Domain

Sequence

MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPF
PFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYRE
ATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGK
LSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVE
TTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCL
SGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQH
GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL
RCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRC
LGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS
LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG
EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP
CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA
LYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS
TGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQH
GGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE
DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDR
TRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTAST
ISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL
SGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINV
TTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRD
GADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARF
GGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGG
TCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYR
VHQDICFKESCESTSLKKTPNRKQSKSQTLEKS

Sequence length

1413

Interactions

View interactions

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Clear cell carcinoma of kidney	Benign	rs59269476, rs75497441	RCV005910359 RCV005910364
Colon adenocarcinoma	Benign	rs59269476	RCV005910357
Malignant tumor of esophagus	Benign	rs59269476, rs75497441	RCV005910358 RCV005910363
Sarcoma	Benign	rs59269476, rs75497441	RCV005910360 RCV005910365
Thyroid cancer, nonmedullary, 1	Benign	rs59269476	RCV005910361
Uterine corpus endometrial carcinoma	Benign	rs59269476, rs75497441	RCV005910362 RCV005910366

Show/Hide Text Mining Associations (13)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenoma	Associate	27587848
Cardiovascular Diseases	Associate	28862951
Colorectal Neoplasms	Associate	18587421
Diabetic Nephropathies	Associate	37986381
Heart Failure	Associate	28862951
Insulinoma	Associate	9284735
Multiple Myeloma	Associate	10029602, 19597816
Neoplasm Metastasis	Associate	38012197
Neoplasms	Associate	10770220, 22068898, 26673010, 29696364, 35799158, 38012197
Neuroendocrine Tumors	Associate	38012197
Thymoma	Associate	10770220
Thymus Neoplasms	Associate	19273275
Thyroid cancer medullary	Associate	22908061, 33248230

SNED1 (sushi, nidogen and EGF like domains 1)