Gene Gene information from NCBI Gene database.
Entrez ID 25987
Gene name Tsukushi, small leucine rich proteoglycan
Gene symbol TSKU
Synonyms (NCBI Gene)
E2IG4LRRC54TSK
Chromosome 11
Chromosome location 11q13.5
miRNA miRNA information provided by mirtarbase database.
986
miRTarBase ID miRNA Experiments Reference
MIRT004908 hsa-miR-124-3p Microarray 15685193
MIRT004908 hsa-miR-124-3p Microarray 15685193
MIRT004908 hsa-miR-124-3p Microarray 18668037
MIRT025821 hsa-miR-7-5p Microarray 19073608
MIRT029592 hsa-miR-26b-5p Microarray 19088304
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
48
GO ID Ontology Definition Evidence Reference
GO:0003431 Process Growth plate cartilage chondrocyte development ISS
GO:0005576 Component Extracellular region IEA
GO:0005615 Component Extracellular space IBA
GO:0005615 Component Extracellular space IEA
GO:0005615 Component Extracellular space ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608015 28850 ENSG00000182704
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WUA8
Protein name Tsukushi (E2-induced gene 4 protein) (Leucine-rich repeat-containing protein 54)
Protein function Contributes to various developmental events and other processes such as wound healing and cholesterol homeostasis through its interactions with multiple signaling pathways. Wnt signaling inhibitor which competes with WNT2B for binding to Wnt rec
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13855 LRR_8 60 120 Leucine rich repeat Repeat
PF13855 LRR_8 108 169 Leucine rich repeat Repeat
PF13855 LRR_8 206 265 Leucine rich repeat Repeat
Sequence
MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRL
RYLESLDLSHNGL
TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLI
HRLVPHPTRAG
LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
RLPELAPSGFRELPGLQVLDLSGNP
KLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL
Sequence length 353
Interactions View interactions