Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID	2597
Gene name	Glyceraldehyde-3-phosphate dehydrogenase
Gene symbol	GAPDH
Synonyms (NCBI Gene)	G3PDGAPDHEL-S-162eP
Chromosome	12
Chromosome location	12p13.31
Summary	This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catal

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001929	hsa-miR-29c-3p	Luciferase reporter assay	18390668
MIRT007162	hsa-miR-644a	Luciferase reporter assayqRT-PCRWestern blot	23091630
MIRT007162	hsa-miR-644a	Luciferase reporter assayqRT-PCRWestern blot	23091630
MIRT052138	hsa-let-7b-5p	CLASH	23622248
MIRT052138	hsa-let-7b-5p	CLASH	23622248
MIRT050952	hsa-miR-17-5p	CLASH	23622248
MIRT050751	hsa-miR-17-3p	CLASH	23622248
MIRT050206	hsa-miR-25-3p	CLASH	23622248
MIRT049457	hsa-miR-92a-3p	CLASH	23622248
MIRT049457	hsa-miR-92a-3p	CLASH	23622248
MIRT048761	hsa-miR-93-5p	CLASH	23622248
MIRT048718	hsa-miR-96-5p	CLASH	23622248
MIRT046276	hsa-miR-23b-3p	CLASH	23622248
MIRT045446	hsa-miR-149-5p	CLASH	23622248
MIRT045446	hsa-miR-149-5p	CLASH	23622248
MIRT045446	hsa-miR-149-5p	CLASH	23622248
MIRT044658	hsa-miR-320a	CLASH	23622248
MIRT043451	hsa-miR-331-3p	CLASH	23622248
MIRT043451	hsa-miR-331-3p	CLASH	23622248
MIRT042878	hsa-miR-324-3p	CLASH	23622248
MIRT041819	hsa-miR-484	CLASH	23622248
MIRT041819	hsa-miR-484	CLASH	23622248
MIRT041139	hsa-miR-501-5p	CLASH	23622248
MIRT039782	hsa-miR-615-3p	CLASH	23622248
MIRT039782	hsa-miR-615-3p	CLASH	23622248
MIRT039782	hsa-miR-615-3p	CLASH	23622248
MIRT039782	hsa-miR-615-3p	CLASH	23622248
MIRT039090	hsa-miR-769-3p	CLASH	23622248
MIRT039028	hsa-miR-766-3p	CLASH	23622248
MIRT038710	hsa-miR-29b-2-5p	CLASH	23622248
MIRT038579	hsa-miR-106b-3p	CLASH	23622248
MIRT038345	hsa-miR-296-3p	CLASH	23622248
MIRT038226	hsa-miR-342-5p	CLASH	23622248
MIRT038105	hsa-miR-423-5p	CLASH	23622248
MIRT038105	hsa-miR-423-5p	CLASH	23622248
MIRT036904	hsa-miR-877-3p	CLASH	23622248
MIRT036280	hsa-miR-1229-3p	CLASH	23622248
MIRT440587	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440587	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT1012003	hsa-miR-1182	CLIP-seq
MIRT1012004	hsa-miR-1207-5p	CLIP-seq
MIRT1012005	hsa-miR-1236	CLIP-seq
MIRT1012006	hsa-miR-1275	CLIP-seq
MIRT1012007	hsa-miR-1294	CLIP-seq
MIRT1012008	hsa-miR-138	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012011	hsa-miR-218	CLIP-seq
MIRT1012012	hsa-miR-2355-5p	CLIP-seq
MIRT1012013	hsa-miR-3150b-3p	CLIP-seq
MIRT1012014	hsa-miR-3175	CLIP-seq
MIRT1012015	hsa-miR-3199	CLIP-seq
MIRT1012016	hsa-miR-323-5p	CLIP-seq
MIRT1012017	hsa-miR-3618	CLIP-seq
MIRT1012018	hsa-miR-3659	CLIP-seq
MIRT1012019	hsa-miR-3663-3p	CLIP-seq
MIRT1012020	hsa-miR-3688-5p	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012022	hsa-miR-4276	CLIP-seq
MIRT1012023	hsa-miR-4283	CLIP-seq
MIRT1012024	hsa-miR-4302	CLIP-seq
MIRT1012025	hsa-miR-4316	CLIP-seq
MIRT1012026	hsa-miR-4447	CLIP-seq
MIRT1012027	hsa-miR-4456	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012029	hsa-miR-4472	CLIP-seq
MIRT1012030	hsa-miR-4489	CLIP-seq
MIRT1012031	hsa-miR-4492	CLIP-seq
MIRT1012032	hsa-miR-4498	CLIP-seq
MIRT1012033	hsa-miR-4519	CLIP-seq
MIRT1012034	hsa-miR-4525	CLIP-seq
MIRT1012035	hsa-miR-4530	CLIP-seq
MIRT1012036	hsa-miR-4652-5p	CLIP-seq
MIRT1012037	hsa-miR-4658	CLIP-seq
MIRT1012038	hsa-miR-4665-5p	CLIP-seq
MIRT1012039	hsa-miR-4677-3p	CLIP-seq
MIRT1012040	hsa-miR-4685-5p	CLIP-seq
MIRT1012041	hsa-miR-4689	CLIP-seq
MIRT1012042	hsa-miR-4723-5p	CLIP-seq
MIRT1012043	hsa-miR-4731-5p	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012045	hsa-miR-4736	CLIP-seq
MIRT1012046	hsa-miR-4740-5p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012050	hsa-miR-4763-3p	CLIP-seq
MIRT1012051	hsa-miR-4779	CLIP-seq
MIRT1012052	hsa-miR-4784	CLIP-seq
MIRT1012053	hsa-miR-4802-3p	CLIP-seq
MIRT1012054	hsa-miR-541	CLIP-seq
MIRT1012055	hsa-miR-574-5p	CLIP-seq
MIRT1012056	hsa-miR-581	CLIP-seq
MIRT1012057	hsa-miR-624	CLIP-seq
MIRT1012058	hsa-miR-625	CLIP-seq
MIRT1012059	hsa-miR-644	CLIP-seq
MIRT1012060	hsa-miR-654-5p	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq
MIRT1012062	hsa-miR-762	CLIP-seq
MIRT1012063	hsa-miR-876-3p	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012017	hsa-miR-3618	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012053	hsa-miR-4802-3p	CLIP-seq
MIRT1012057	hsa-miR-624	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq
MIRT1012003	hsa-miR-1182	CLIP-seq
MIRT1012004	hsa-miR-1207-5p	CLIP-seq
MIRT1012005	hsa-miR-1236	CLIP-seq
MIRT1012006	hsa-miR-1275	CLIP-seq
MIRT1012007	hsa-miR-1294	CLIP-seq
MIRT1012008	hsa-miR-138	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012011	hsa-miR-218	CLIP-seq
MIRT1012012	hsa-miR-2355-5p	CLIP-seq
MIRT1012013	hsa-miR-3150b-3p	CLIP-seq
MIRT1012014	hsa-miR-3175	CLIP-seq
MIRT1012015	hsa-miR-3199	CLIP-seq
MIRT1012016	hsa-miR-323-5p	CLIP-seq
MIRT1012017	hsa-miR-3618	CLIP-seq
MIRT1012018	hsa-miR-3659	CLIP-seq
MIRT1012019	hsa-miR-3663-3p	CLIP-seq
MIRT1012020	hsa-miR-3688-5p	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012022	hsa-miR-4276	CLIP-seq
MIRT1012023	hsa-miR-4283	CLIP-seq
MIRT1012024	hsa-miR-4302	CLIP-seq
MIRT1012025	hsa-miR-4316	CLIP-seq
MIRT1012026	hsa-miR-4447	CLIP-seq
MIRT1012027	hsa-miR-4456	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012029	hsa-miR-4472	CLIP-seq
MIRT1012030	hsa-miR-4489	CLIP-seq
MIRT1012031	hsa-miR-4492	CLIP-seq
MIRT1012032	hsa-miR-4498	CLIP-seq
MIRT1012033	hsa-miR-4519	CLIP-seq
MIRT1012034	hsa-miR-4525	CLIP-seq
MIRT1012035	hsa-miR-4530	CLIP-seq
MIRT1012036	hsa-miR-4652-5p	CLIP-seq
MIRT1012037	hsa-miR-4658	CLIP-seq
MIRT1012038	hsa-miR-4665-5p	CLIP-seq
MIRT1012039	hsa-miR-4677-3p	CLIP-seq
MIRT1012040	hsa-miR-4685-5p	CLIP-seq
MIRT1012041	hsa-miR-4689	CLIP-seq
MIRT1012042	hsa-miR-4723-5p	CLIP-seq
MIRT1012043	hsa-miR-4731-5p	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012045	hsa-miR-4736	CLIP-seq
MIRT1012046	hsa-miR-4740-5p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012050	hsa-miR-4763-3p	CLIP-seq
MIRT1012051	hsa-miR-4779	CLIP-seq
MIRT1012052	hsa-miR-4784	CLIP-seq
MIRT1012053	hsa-miR-4802-3p	CLIP-seq
MIRT1012054	hsa-miR-541	CLIP-seq
MIRT1012055	hsa-miR-574-5p	CLIP-seq
MIRT1012056	hsa-miR-581	CLIP-seq
MIRT1012057	hsa-miR-624	CLIP-seq
MIRT1012058	hsa-miR-625	CLIP-seq
MIRT1012059	hsa-miR-644	CLIP-seq
MIRT1012060	hsa-miR-654-5p	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq
MIRT1012062	hsa-miR-762	CLIP-seq
MIRT1012063	hsa-miR-876-3p	CLIP-seq
MIRT1012003	hsa-miR-1182	CLIP-seq
MIRT1012004	hsa-miR-1207-5p	CLIP-seq
MIRT1012005	hsa-miR-1236	CLIP-seq
MIRT1012006	hsa-miR-1275	CLIP-seq
MIRT1012007	hsa-miR-1294	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012011	hsa-miR-218	CLIP-seq
MIRT1012012	hsa-miR-2355-5p	CLIP-seq
MIRT1012013	hsa-miR-3150b-3p	CLIP-seq
MIRT1012014	hsa-miR-3175	CLIP-seq
MIRT1012015	hsa-miR-3199	CLIP-seq
MIRT1012017	hsa-miR-3618	CLIP-seq
MIRT1012018	hsa-miR-3659	CLIP-seq
MIRT1012019	hsa-miR-3663-3p	CLIP-seq
MIRT1012020	hsa-miR-3688-5p	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012022	hsa-miR-4276	CLIP-seq
MIRT1012024	hsa-miR-4302	CLIP-seq
MIRT1012025	hsa-miR-4316	CLIP-seq
MIRT1012026	hsa-miR-4447	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012029	hsa-miR-4472	CLIP-seq
MIRT1012033	hsa-miR-4519	CLIP-seq
MIRT1012034	hsa-miR-4525	CLIP-seq
MIRT1012036	hsa-miR-4652-5p	CLIP-seq
MIRT1012037	hsa-miR-4658	CLIP-seq
MIRT1012038	hsa-miR-4665-5p	CLIP-seq
MIRT1012039	hsa-miR-4677-3p	CLIP-seq
MIRT1012041	hsa-miR-4689	CLIP-seq
MIRT1012042	hsa-miR-4723-5p	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012045	hsa-miR-4736	CLIP-seq
MIRT1012046	hsa-miR-4740-5p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012050	hsa-miR-4763-3p	CLIP-seq
MIRT1012051	hsa-miR-4779	CLIP-seq
MIRT1012052	hsa-miR-4784	CLIP-seq
MIRT1012053	hsa-miR-4802-3p	CLIP-seq
MIRT1012054	hsa-miR-541	CLIP-seq
MIRT1012055	hsa-miR-574-5p	CLIP-seq
MIRT1012056	hsa-miR-581	CLIP-seq
MIRT1012057	hsa-miR-624	CLIP-seq
MIRT1012058	hsa-miR-625	CLIP-seq
MIRT1012059	hsa-miR-644	CLIP-seq
MIRT1012060	hsa-miR-654-5p	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq
MIRT1012005	hsa-miR-1236	CLIP-seq
MIRT1012004	hsa-miR-1207-5p	CLIP-seq
MIRT1012006	hsa-miR-1275	CLIP-seq
MIRT1012007	hsa-miR-1294	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012012	hsa-miR-2355-5p	CLIP-seq
MIRT1012013	hsa-miR-3150b-3p	CLIP-seq
MIRT1012014	hsa-miR-3175	CLIP-seq
MIRT1012015	hsa-miR-3199	CLIP-seq
MIRT1012017	hsa-miR-3618	CLIP-seq
MIRT1012018	hsa-miR-3659	CLIP-seq
MIRT1012020	hsa-miR-3688-5p	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012022	hsa-miR-4276	CLIP-seq
MIRT1012024	hsa-miR-4302	CLIP-seq
MIRT1012025	hsa-miR-4316	CLIP-seq
MIRT1012026	hsa-miR-4447	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012029	hsa-miR-4472	CLIP-seq
MIRT1012034	hsa-miR-4525	CLIP-seq
MIRT1012036	hsa-miR-4652-5p	CLIP-seq
MIRT1012037	hsa-miR-4658	CLIP-seq
MIRT1012038	hsa-miR-4665-5p	CLIP-seq
MIRT1012039	hsa-miR-4677-3p	CLIP-seq
MIRT1012041	hsa-miR-4689	CLIP-seq
MIRT1012042	hsa-miR-4723-5p	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012045	hsa-miR-4736	CLIP-seq
MIRT1012046	hsa-miR-4740-5p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012050	hsa-miR-4763-3p	CLIP-seq
MIRT1012051	hsa-miR-4779	CLIP-seq
MIRT1012052	hsa-miR-4784	CLIP-seq
MIRT1012053	hsa-miR-4802-3p	CLIP-seq
MIRT1012054	hsa-miR-541	CLIP-seq
MIRT1012055	hsa-miR-574-5p	CLIP-seq
MIRT1012057	hsa-miR-624	CLIP-seq
MIRT1012058	hsa-miR-625	CLIP-seq
MIRT1012059	hsa-miR-644	CLIP-seq
MIRT1012060	hsa-miR-654-5p	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq
MIRT1012004	hsa-miR-1207-5p	CLIP-seq
MIRT1012006	hsa-miR-1275	CLIP-seq
MIRT1012007	hsa-miR-1294	CLIP-seq
MIRT1012009	hsa-miR-18a	CLIP-seq
MIRT1012010	hsa-miR-18b	CLIP-seq
MIRT1012012	hsa-miR-2355-5p	CLIP-seq
MIRT1012013	hsa-miR-3150b-3p	CLIP-seq
MIRT1012014	hsa-miR-3175	CLIP-seq
MIRT1012015	hsa-miR-3199	CLIP-seq
MIRT1012017	hsa-miR-3618	CLIP-seq
MIRT1012018	hsa-miR-3659	CLIP-seq
MIRT1012020	hsa-miR-3688-5p	CLIP-seq
MIRT1012021	hsa-miR-3936	CLIP-seq
MIRT1012022	hsa-miR-4276	CLIP-seq
MIRT1012024	hsa-miR-4302	CLIP-seq
MIRT1012025	hsa-miR-4316	CLIP-seq
MIRT1012026	hsa-miR-4447	CLIP-seq
MIRT1012028	hsa-miR-4466	CLIP-seq
MIRT1012029	hsa-miR-4472	CLIP-seq
MIRT1012034	hsa-miR-4525	CLIP-seq
MIRT1012036	hsa-miR-4652-5p	CLIP-seq
MIRT1012037	hsa-miR-4658	CLIP-seq
MIRT1012038	hsa-miR-4665-5p	CLIP-seq
MIRT1012039	hsa-miR-4677-3p	CLIP-seq
MIRT1012041	hsa-miR-4689	CLIP-seq
MIRT1012042	hsa-miR-4723-5p	CLIP-seq
MIRT1012044	hsa-miR-4735-3p	CLIP-seq
MIRT1012045	hsa-miR-4736	CLIP-seq
MIRT1012046	hsa-miR-4740-5p	CLIP-seq
MIRT1012047	hsa-miR-4747-3p	CLIP-seq
MIRT1012048	hsa-miR-4749-3p	CLIP-seq
MIRT1012049	hsa-miR-4761-5p	CLIP-seq
MIRT1012050	hsa-miR-4763-3p	CLIP-seq
MIRT1012051	hsa-miR-4779	CLIP-seq
MIRT1012052	hsa-miR-4784	CLIP-seq
MIRT1012053	hsa-miR-4802-3p	CLIP-seq
MIRT1012054	hsa-miR-541	CLIP-seq
MIRT1012055	hsa-miR-574-5p	CLIP-seq
MIRT1012057	hsa-miR-624	CLIP-seq
MIRT1012058	hsa-miR-625	CLIP-seq
MIRT1012059	hsa-miR-644	CLIP-seq
MIRT1012060	hsa-miR-654-5p	CLIP-seq
MIRT1012061	hsa-miR-675	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
CEBPA	Unknown	12842822
CEBPD	Unknown	12842822
HIF1A	Unknown	11955624

Show/Hide all (63)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000226	Process	Microtubule cytoskeleton organization	ISS
GO:0001819	Process	Positive regulation of cytokine production	IDA	22832495
GO:0002376	Process	Immune system process	IEA
GO:0004365	Function	Glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IBA
GO:0004365	Function	Glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IEA
GO:0004365	Function	Glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	ISS
GO:0004365	Function	Glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	NAS	3170585, 7030790
GO:0005515	Function	Protein binding	IPI	11724794, 15628863, 16169070, 16799092, 17500595, 17540579, 20029029, 20392205, 20849852, 21044950, 23332158, 23348613, 23355646, 24658140, 25417112, 27387501, 28514442, 29028794, 29128334, 31980649, 32814053, 33961781
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IDA	28404743
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IDA	11785981, 24507776
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005811	Component	Lipid droplet	IDA	14741744
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	24101517, 28404743
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	ISS
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0006006	Process	Glucose metabolic process	IEA
GO:0006096	Process	Glycolytic process	IBA
GO:0006096	Process	Glycolytic process	IEA
GO:0006417	Process	Regulation of translation	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0008017	Function	Microtubule binding	ISS
GO:0010951	Process	Negative regulation of endopeptidase activity	IDA	22832495
GO:0015630	Component	Microtubule cytoskeleton	ISS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016241	Process	Regulation of macroautophagy	TAS	26626483
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016620	Function	Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0017148	Process	Negative regulation of translation	IDA	23071094
GO:0017148	Process	Negative regulation of translation	IMP	15479637
GO:0019828	Function	Aspartic-type endopeptidase inhibitor activity	IDA	22832495
GO:0031640	Process	Killing of cells of another organism	IDA	22832495
GO:0031965	Component	Nuclear membrane	IDA
GO:0031982	Component	Vesicle	HDA	19190083
GO:0032481	Process	Positive regulation of type I interferon production	IDA	27387501
GO:0035605	Function	Peptidyl-cysteine S-nitrosylase activity	IEA
GO:0035605	Function	Peptidyl-cysteine S-nitrosylase activity	ISS
GO:0035606	Process	Peptidyl-cysteine S-trans-nitrosylation	ISS
GO:0042802	Function	Identical protein binding	IPI	20392205, 21988832
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	23332158
GO:0045087	Process	Innate immune response	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050661	Function	NADP binding	IEA
GO:0050821	Process	Protein stabilization	ISS
GO:0050832	Process	Defense response to fungus	IDA	22832495
GO:0051287	Function	NAD binding	IEA
GO:0051402	Process	Neuron apoptotic process	ISS
GO:0051873	Process	Killing by host of symbiont cells	IDA	22832495
GO:0061844	Process	Antimicrobial humoral immune response mediated by antimicrobial peptide	IDA	22832495
GO:0070062	Component	Extracellular exosome	HDA	11487543, 12519789, 19056867, 19199708, 20458337, 21362503, 23533145
GO:0071346	Process	Cellular response to type II interferon	IDA	15479637
GO:0097452	Component	GAIT complex	IDA	15479637, 23071094
GO:0097718	Function	Disordered domain specific binding	IPI	11785981
GO:1990904	Component	Ribonucleoprotein complex	IDA	15479637

MIM	HGNC	e!Ensembl
138400	4141	ENSG00000111640

P04406

Protein name

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)

Protein function

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively (PubMed:11724794, PubMed:3170585). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in

PDB

1U8F , 1ZNQ , 3GPD , 4WNC , 4WNI , 6ADE , 6IQ6 , 6M61 , 6YND , 6YNE , 6YNF , 6YNH , 8DNS , 8G12 , 8G13 , 8G14 , 8G15 , 8G16 , 8G17 , 8P5F

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00044	Gp_dh_N	4 → 105	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	Domain
PF02800	Gp_dh_C	157 → 314	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain	Domain

Sequence

MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV
KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI
ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA
ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV
SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE

Sequence length

335

Interactions

View interactions

	KEGG		Reactome
	Glycolysis / Gluconeogenesis Metabolic pathways Carbon metabolism Biosynthesis of amino acids HIF-1 signaling pathway Alzheimer disease Pathogenic Escherichia coli infection Salmonella infection Diabetic cardiomyopathy		Glycolysis Gluconeogenesis

GAPDH (glyceraldehyde-3-phosphate dehydrogenase)