Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	25926
Gene name Gene Name - the full gene name approved by the HGNC.	Nucleolar protein 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NOL11
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q24.2

Show/Hide all(153)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031623	hsa-miR-16-5p	Proteomics	18668040
MIRT039042	hsa-miR-766-3p	CLASH	23622248
MIRT052834	hsa-miR-4323	CLASH	23622248
MIRT532133	hsa-miR-3662	PAR-CLIP	22012620
MIRT532132	hsa-miR-1276	PAR-CLIP	22012620
MIRT532131	hsa-miR-3163	PAR-CLIP	22012620
MIRT532130	hsa-miR-4796-5p	PAR-CLIP	22012620
MIRT532129	hsa-miR-340-5p	PAR-CLIP	22012620
MIRT532128	hsa-miR-130a-5p	PAR-CLIP	22012620
MIRT532127	hsa-miR-23a-3p	PAR-CLIP	22012620
MIRT532126	hsa-miR-23b-3p	PAR-CLIP	22012620
MIRT532125	hsa-miR-23c	PAR-CLIP	22012620
MIRT532133	hsa-miR-3662	PAR-CLIP	22012620
MIRT532132	hsa-miR-1276	PAR-CLIP	22012620
MIRT532131	hsa-miR-3163	PAR-CLIP	22012620
MIRT532130	hsa-miR-4796-5p	PAR-CLIP	22012620
MIRT532129	hsa-miR-340-5p	PAR-CLIP	22012620
MIRT532128	hsa-miR-130a-5p	PAR-CLIP	22012620
MIRT532127	hsa-miR-23a-3p	PAR-CLIP	22012620
MIRT532126	hsa-miR-23b-3p	PAR-CLIP	22012620
MIRT532125	hsa-miR-23c	PAR-CLIP	22012620
MIRT1188447	hsa-miR-1254	CLIP-seq
MIRT1188448	hsa-miR-1255a	CLIP-seq
MIRT1188449	hsa-miR-1255b	CLIP-seq
MIRT1188450	hsa-miR-1273f	CLIP-seq
MIRT1188451	hsa-miR-143	CLIP-seq
MIRT1188452	hsa-miR-23a	CLIP-seq
MIRT1188453	hsa-miR-23b	CLIP-seq
MIRT1188454	hsa-miR-3116	CLIP-seq
MIRT1188455	hsa-miR-3117-5p	CLIP-seq
MIRT1188456	hsa-miR-3680	CLIP-seq
MIRT1188457	hsa-miR-4420	CLIP-seq
MIRT1188458	hsa-miR-4462	CLIP-seq
MIRT1188459	hsa-miR-451b	CLIP-seq
MIRT1188460	hsa-miR-4708-5p	CLIP-seq
MIRT1188461	hsa-miR-4753-3p	CLIP-seq
MIRT1188462	hsa-miR-4768-5p	CLIP-seq
MIRT1188463	hsa-miR-4770	CLIP-seq
MIRT1188464	hsa-miR-4798-3p	CLIP-seq
MIRT1188465	hsa-miR-514	CLIP-seq
MIRT1188466	hsa-miR-514b-3p	CLIP-seq
MIRT1188467	hsa-miR-661	CLIP-seq
MIRT1188447	hsa-miR-1254	CLIP-seq
MIRT1188448	hsa-miR-1255a	CLIP-seq
MIRT1188449	hsa-miR-1255b	CLIP-seq
MIRT1188450	hsa-miR-1273f	CLIP-seq
MIRT1188451	hsa-miR-143	CLIP-seq
MIRT1188452	hsa-miR-23a	CLIP-seq
MIRT1188453	hsa-miR-23b	CLIP-seq
MIRT2054565	hsa-miR-298	CLIP-seq
MIRT1188454	hsa-miR-3116	CLIP-seq
MIRT1188455	hsa-miR-3117-5p	CLIP-seq
MIRT2054566	hsa-miR-340	CLIP-seq
MIRT2054567	hsa-miR-3678-3p	CLIP-seq
MIRT1188458	hsa-miR-4462	CLIP-seq
MIRT1188459	hsa-miR-451b	CLIP-seq
MIRT1188460	hsa-miR-4708-5p	CLIP-seq
MIRT1188461	hsa-miR-4753-3p	CLIP-seq
MIRT1188462	hsa-miR-4768-5p	CLIP-seq
MIRT1188463	hsa-miR-4770	CLIP-seq
MIRT1188465	hsa-miR-514	CLIP-seq
MIRT1188466	hsa-miR-514b-3p	CLIP-seq
MIRT1188467	hsa-miR-661	CLIP-seq
MIRT1188447	hsa-miR-1254	CLIP-seq
MIRT1188448	hsa-miR-1255a	CLIP-seq
MIRT1188449	hsa-miR-1255b	CLIP-seq
MIRT1188450	hsa-miR-1273f	CLIP-seq
MIRT1188451	hsa-miR-143	CLIP-seq
MIRT1188452	hsa-miR-23a	CLIP-seq
MIRT1188453	hsa-miR-23b	CLIP-seq
MIRT1188454	hsa-miR-3116	CLIP-seq
MIRT1188455	hsa-miR-3117-5p	CLIP-seq
MIRT1188456	hsa-miR-3680	CLIP-seq
MIRT1188457	hsa-miR-4420	CLIP-seq
MIRT1188458	hsa-miR-4462	CLIP-seq
MIRT1188459	hsa-miR-451b	CLIP-seq
MIRT1188460	hsa-miR-4708-5p	CLIP-seq
MIRT1188461	hsa-miR-4753-3p	CLIP-seq
MIRT1188462	hsa-miR-4768-5p	CLIP-seq
MIRT1188463	hsa-miR-4770	CLIP-seq
MIRT1188464	hsa-miR-4798-3p	CLIP-seq
MIRT1188465	hsa-miR-514	CLIP-seq
MIRT1188466	hsa-miR-514b-3p	CLIP-seq
MIRT1188467	hsa-miR-661	CLIP-seq
MIRT2283704	hsa-miR-935	CLIP-seq
MIRT1188447	hsa-miR-1254	CLIP-seq
MIRT1188448	hsa-miR-1255a	CLIP-seq
MIRT1188449	hsa-miR-1255b	CLIP-seq
MIRT1188450	hsa-miR-1273f	CLIP-seq
MIRT1188451	hsa-miR-143	CLIP-seq
MIRT1188452	hsa-miR-23a	CLIP-seq
MIRT1188453	hsa-miR-23b	CLIP-seq
MIRT1188454	hsa-miR-3116	CLIP-seq
MIRT1188455	hsa-miR-3117-5p	CLIP-seq
MIRT1188458	hsa-miR-4462	CLIP-seq
MIRT1188459	hsa-miR-451b	CLIP-seq
MIRT1188460	hsa-miR-4708-5p	CLIP-seq
MIRT1188461	hsa-miR-4753-3p	CLIP-seq
MIRT1188462	hsa-miR-4768-5p	CLIP-seq
MIRT1188463	hsa-miR-4770	CLIP-seq
MIRT1188465	hsa-miR-514	CLIP-seq
MIRT1188466	hsa-miR-514b-3p	CLIP-seq
MIRT1188467	hsa-miR-661	CLIP-seq
MIRT2581857	hsa-miR-1203	CLIP-seq
MIRT2581858	hsa-miR-1252	CLIP-seq
MIRT1188447	hsa-miR-1254	CLIP-seq
MIRT1188448	hsa-miR-1255a	CLIP-seq
MIRT1188449	hsa-miR-1255b	CLIP-seq
MIRT1188450	hsa-miR-1273f	CLIP-seq
MIRT1188451	hsa-miR-143	CLIP-seq
MIRT2581859	hsa-miR-1910	CLIP-seq
MIRT1188452	hsa-miR-23a	CLIP-seq
MIRT1188453	hsa-miR-23b	CLIP-seq
MIRT1188454	hsa-miR-3116	CLIP-seq
MIRT1188455	hsa-miR-3117-5p	CLIP-seq
MIRT2054566	hsa-miR-340	CLIP-seq
MIRT2581860	hsa-miR-4428	CLIP-seq
MIRT1188458	hsa-miR-4462	CLIP-seq
MIRT1188459	hsa-miR-451b	CLIP-seq
MIRT1188460	hsa-miR-4708-5p	CLIP-seq
MIRT2581861	hsa-miR-4711-5p	CLIP-seq
MIRT1188461	hsa-miR-4753-3p	CLIP-seq
MIRT1188462	hsa-miR-4768-5p	CLIP-seq
MIRT1188463	hsa-miR-4770	CLIP-seq
MIRT1188465	hsa-miR-514	CLIP-seq
MIRT1188466	hsa-miR-514b-3p	CLIP-seq
MIRT1188467	hsa-miR-661	CLIP-seq
MIRT2283704	hsa-miR-935	CLIP-seq
MIRT2581857	hsa-miR-1203	CLIP-seq
MIRT2581858	hsa-miR-1252	CLIP-seq
MIRT1188447	hsa-miR-1254	CLIP-seq
MIRT1188448	hsa-miR-1255a	CLIP-seq
MIRT1188449	hsa-miR-1255b	CLIP-seq
MIRT1188450	hsa-miR-1273f	CLIP-seq
MIRT1188451	hsa-miR-143	CLIP-seq
MIRT2581859	hsa-miR-1910	CLIP-seq
MIRT1188452	hsa-miR-23a	CLIP-seq
MIRT1188453	hsa-miR-23b	CLIP-seq
MIRT1188454	hsa-miR-3116	CLIP-seq
MIRT1188455	hsa-miR-3117-5p	CLIP-seq
MIRT2054566	hsa-miR-340	CLIP-seq
MIRT2581860	hsa-miR-4428	CLIP-seq
MIRT1188458	hsa-miR-4462	CLIP-seq
MIRT1188459	hsa-miR-451b	CLIP-seq
MIRT1188460	hsa-miR-4708-5p	CLIP-seq
MIRT2581861	hsa-miR-4711-5p	CLIP-seq
MIRT1188461	hsa-miR-4753-3p	CLIP-seq
MIRT1188462	hsa-miR-4768-5p	CLIP-seq
MIRT1188463	hsa-miR-4770	CLIP-seq
MIRT1188465	hsa-miR-514	CLIP-seq
MIRT1188466	hsa-miR-514b-3p	CLIP-seq
MIRT1188467	hsa-miR-661	CLIP-seq
MIRT2283704	hsa-miR-935	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	22916032, 28514442
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IBA	21873635
GO:0005730	Component	Nucleolus	IDA	22916032
GO:0006364	Process	RRNA processing	TAS
GO:0030490	Process	Maturation of SSU-rRNA	IBA	21873635
GO:0030490	Process	Maturation of SSU-rRNA	IMP	22916032
GO:0034455	Component	T-UTP complex	IDA	22916032
GO:1901838	Process	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	IMP	22916032

MIM	HGNC	e!Ensembl
615366	24557	ENSG00000130935

Protein

UniProt ID

Q9H8H0

Protein name

Nucleolar protein 11

Protein function

Ribosome biogenesis factor. May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08168	NUC205	200 → 243	NUC205 domain	Domain

Sequence

MAALEEEFTLSSVVLSAGPEGLLGVEQSDKTDQFLVTDSGRTVILYKVSDQKPLGSWSVK
QGQIITCPAVCNFQTGEYVVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRILSVQGTEP
LVLFKEGAVRGLEALLADPQQKIETVISDEEVIKWTKFFVVFRHPVLIFITEKHGNYFAY
VQMFNSRILTKYTLLLGQDENSVIKSFTASVDRKFISLMSLSSDGCIYETLIPIRPADPE
KNQSLVKSLLLKAVVSGNARNGVALTALDQDHVAVLGSPLAASKECLSVWNIKFQTLQTS
KELPQGTSGQLWYYGEHLFMLHGKSLTVIPYKCEVSSLAGALGKLKHSQDPGTHVVSHFV
NWETPQGCGLGFQNSEQSRRILRRRKIEVSLQPEVPPSKQLLSTIMKDSEKHIEVEVRKF
LALKQTPDFHTVIGDTVTGLLERCKAEPSFYPRNCLMQLIQTHVLSYSLCPDLMEIALKK
KDVQLLQLCLQQFPDIPESVTCACLKIFLSIGDDSLQETDVNMESVFDYSINSVHDEKME
EQTEILQNGFNPEEDKCNNCDQELNKKPQDETKESTSCPVVQKRAALLNAILHSAYSETF
LLPHLKDIPAQHITLFLKYLYFLYLKCSENATMTLPGIHPPTLNQIMDWICLLLDANFTV
VVMMPEAKRLLINLYKLVKSQISVYSELNKIEVSFRELQKLNQEKNNRGLYSIEVLELF

Sequence length

719

Interactions

View interactions

	Reactome
			Major pathway of rRNA processing in the nucleolus and cytosol

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Oligodontia	Oligodontia	rs1591901585	29364747
Tooth agenesis	Tooth Agenesis, Selective, With Orofacial Cleft, Tooth Agenesis, Familial, TOOTH AGENESIS, SELECTIVE, 9	rs121908119, rs121908121, rs1881345182, rs104894467, rs28933970, rs2139108031, rs28933971, rs28933972, rs1594475481, rs2139106532, rs2139108874, rs121917720, rs121913129, rs104893852, rs104893850 View all (22 more)	29364747

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining
Fibrosis	Associate	22916032
North American Indian Childhood Cirrhosis	Associate	22916032

NOL11 (nucleolar protein 11)