Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
25921
Gene name Gene Name - the full gene name approved by the HGNC.
ZDHHC palmitoyltransferase 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZDHHC5
Synonyms (NCBI Gene) Gene synonyms aliases
DHHC5, ZNF375
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028354 hsa-miR-32-5p Sequencing 20371350
MIRT046025 hsa-miR-125b-5p CLASH 23622248
MIRT043482 hsa-miR-331-3p CLASH 23622248
MIRT510455 hsa-miR-329-3p HITS-CLIP 21572407
MIRT510454 hsa-miR-362-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 31402609
GO:0005886 Component Plasma membrane IBA 21873635
GO:0005886 Component Plasma membrane IDA 16647879, 31402609, 31649195
GO:0016020 Component Membrane HDA 19946888
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614586 18472 ENSG00000156599
Protein
UniProt ID Q9C0B5
Protein name Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375)
Protein function Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates such as CTNND2, CD36, GSDMD, NLRP3, NOD1, NOD2, STAT3 and S1PR1 thus plays a role in various biological processes including cell adhesion, inflammation
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01529 DHHC 99 224 DHHC palmitoyltransferase Family
Sequence
MPAESGKRFKPSKYVPVSAAAIFLVGATTLFFAFTCPGLSLYVSPAVPIYNAIMFLFVLA
NFSMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIKGIQVRMKWCATCRFYRPPRCSHC
SVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEELSG
VRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGK
FRGGVNPFTNGCCNNV
SRVLCSSPAPRYLGRPKKEKTIVIRPPFLRPEVSDGQITVKIMDNGIQGELRRTKSKGSL
EITESQSADAEPPPPPKPDLSRYTGLRTHLGLATNEDSSLLAKDSPPTPTMYKYRPGYSS
SSTSAAMPHSSSAKLSRGDSLKEPTSIAESSRHPSYRSEPSLEPESFRSPTFGKSFHFDP
LSSGSRSSSLKSAQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGSLSYDSLLTPSDSP
DFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLVPTGPTHREPSPVRYDNLSRHI
VASLQEREKLLRQSPPLPGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLGKTPL
GRPAVPRFGKPDGLRGRGVGSPEPGPTAPYLGRSMSYSSQKAQPGVSETEEVALQPLLTP
KDEVQLKTTYSKSNGQPKSLGSASPGPGQPPLSSPTRGGVKKVSGVGGTTYEISV
Sequence length 715
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 29942085 ClinVar
Neuroticism Neuroticism GWAS
Anxiety Disorder Anxiety Disorder GWAS
Hypertension Hypertension GWAS
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Squamous Cell Associate 28186972
Endotoxemia Associate 34668383
Neoplasms Associate 28186972
Severe Acute Respiratory Syndrome Associate 33913101
Thrombosis Associate 34668383