OLFML2B (olfactomedin like 2B)

Gene

• Entrez ID: 25903
• Gene name: Olfactomedin like 2B
• Gene symbol: OLFML2B
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1q23.3
• Summary: This gene encodes an olfactomedin domain-containing protein. Most olfactomedin domain-containing proteins are secreted glycoproteins. [provided by RefSeq, Dec 2016]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT046128	hsa-miR-30b-5p	CLASH	23622248
MIRT1203265	hsa-miR-3135b	CLIP-seq
MIRT1203266	hsa-miR-3184	CLIP-seq
MIRT1203267	hsa-miR-423-5p	CLIP-seq
MIRT1203268	hsa-miR-432	CLIP-seq
MIRT1203269	hsa-miR-4487	CLIP-seq
MIRT1203270	hsa-miR-4493	CLIP-seq
MIRT1203271	hsa-miR-4633-3p	CLIP-seq
MIRT1203272	hsa-miR-4656	CLIP-seq
MIRT1203273	hsa-miR-548a-3p	CLIP-seq
MIRT1203274	hsa-miR-548e	CLIP-seq
MIRT1203275	hsa-miR-548f	CLIP-seq
MIRT1203276	hsa-miR-890	CLIP-seq
MIRT2455631	hsa-miR-3152-5p	CLIP-seq
MIRT2455632	hsa-miR-578	CLIP-seq
MIRT2455631	hsa-miR-3152-5p	CLIP-seq
MIRT2455632	hsa-miR-578	CLIP-seq
MIRT1203265	hsa-miR-3135b	CLIP-seq
MIRT1203266	hsa-miR-3184	CLIP-seq
MIRT2585207	hsa-miR-3672	CLIP-seq
MIRT1203267	hsa-miR-423-5p	CLIP-seq
MIRT1203268	hsa-miR-432	CLIP-seq
MIRT1203269	hsa-miR-4487	CLIP-seq
MIRT1203270	hsa-miR-4493	CLIP-seq
MIRT1203271	hsa-miR-4633-3p	CLIP-seq
MIRT2585208	hsa-miR-4635	CLIP-seq
MIRT1203272	hsa-miR-4656	CLIP-seq
MIRT1203276	hsa-miR-890	CLIP-seq
MIRT2686835	hsa-miR-1252	CLIP-seq
MIRT1203265	hsa-miR-3135b	CLIP-seq
MIRT1203266	hsa-miR-3184	CLIP-seq
MIRT2585207	hsa-miR-3672	CLIP-seq
MIRT2686836	hsa-miR-409-5p	CLIP-seq
MIRT1203267	hsa-miR-423-5p	CLIP-seq
MIRT1203268	hsa-miR-432	CLIP-seq
MIRT2686837	hsa-miR-4428	CLIP-seq
MIRT2686838	hsa-miR-4434	CLIP-seq
MIRT2686839	hsa-miR-4476	CLIP-seq
MIRT1203269	hsa-miR-4487	CLIP-seq
MIRT1203270	hsa-miR-4493	CLIP-seq
MIRT2686840	hsa-miR-4516	CLIP-seq
MIRT1203271	hsa-miR-4633-3p	CLIP-seq
MIRT2585208	hsa-miR-4635	CLIP-seq
MIRT1203272	hsa-miR-4656	CLIP-seq
MIRT2686841	hsa-miR-507	CLIP-seq
MIRT2686842	hsa-miR-557	CLIP-seq
MIRT2686843	hsa-miR-579	CLIP-seq
MIRT2686844	hsa-miR-876-3p	CLIP-seq
MIRT1203276	hsa-miR-890	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0007165	Process	Signal transduction	IBA
GO:0030198	Process	Extracellular matrix organization	IEA
GO:0031012	Component	Extracellular matrix	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0050840	Function	Extracellular matrix binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q68BL8
• Protein name: Olfactomedin-like protein 2B (Photomedin-2)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02191	OLF	498 → 748	Olfactomedin-like domain	Family

• Sequence:

  MAKPRLLVLYFALIVVPAWVSSIVLTGTSEPPDAQTVAPAEDETLQNEADNQENVLSQLL
  GDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGSSCKCACVA
  PPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKL
  EEEVSKNLTKENEQIKEDMEEIRTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHP
  EYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQPTVIRGIT
  YYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAV
  TSDLNARTAPWSSALPQPSTSDPSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATT
  VAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGTTPASPTLS
  PEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLV
  EFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAM
  LHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAADLSTQK
  ETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSY
  TTQIDYNPKDRLLYAWDNGHQVTYHVIFAY

• Sequence length: 750

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Hepatocellular carcinoma	Uncertain significance	rs532457018	RCV005931050

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Hepatocellular	Associate	37340445
Neoplasms	Associate	37340445
Stomach Neoplasms	Associate	30866865, 32908579, 33015704
Triple Negative Breast Neoplasms	Associate	36999020
Urinary Bladder Neoplasms	Associate	33204728