INTS7 (integrator complex subunit 7)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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25896 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Integrator complex subunit 7 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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INTS7 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C1orf73, INT7 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q32.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3`-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||
UniProt ID | Q9NVH2 | |
Protein name | Integrator complex subunit 7 (Int7) | |
Protein function | Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:33243860, PubMed:38570683). The integrator complex provides a quality checkpoin | |
PDB | 7CUN , 7PKS , 7YCX , 8RBX , 8RBZ , 8RC4 , 8YJB | |
Family and domains | ||
Sequence |
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Sequence length | 962 | |
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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