MPC2 (mitochondrial pyruvate carrier 2)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
25874
Gene name Gene Name - the full gene name approved by the HGNC.
Mitochondrial pyruvate carrier 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MPC2
Synonyms (NCBI Gene) Gene synonyms aliases
BRP44, SLC54A2
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q24.2
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT030303 hsa-miR-26b-5p Microarray 19088304
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(9)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183, 32814053
GO:0005634 Component Nucleus HDA 21630459
GO:0005739 Component Mitochondrion IDA
GO:0006850 Process Mitochondrial pyruvate transmembrane transport IBA 21873635
GO:0031305 Component Integral component of mitochondrial inner membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
614737 24515 ENSG00000143158
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID O95563
Protein name Mitochondrial pyruvate carrier 2 (Brain protein 44)
Protein function Mediates the uptake of pyruvate into mitochondria.
PDB 8YW6 , 8YW8 , 8YW9 , 9KNW , 9KNX , 9KNY , 9MNW , 9MNX , 9MNY , 9MNZ , 9MO0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03650 MPC 27 → 127 Mitochondrial pyruvate carriers Family
Sequence
Sequence length 127
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Diabetic cardiomyopathy  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)		 22037555
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Metabolic Diseases metabolic disease GenCC
Show/Hide Text Mining Associations (9)
Associations from Text Mining
Disease Name Relationship Type References
Diabetic Nephropathies Inhibit 32664896
Glioma Associate 35242216
Infantile Epileptic Dyskinetic Encephalopathy Associate 36417180
Lymphatic Metastasis Associate 27852261
Neoplasms Associate 33243007
Parvovirus antenatal infection Associate 36417180
Prostatic Neoplasms Associate 27852261
Pyruvate Metabolism Inborn Errors Associate 36417180
Schizophrenia Associate 22037555