Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	25873
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal protein L36
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RPL36
Synonyms (NCBI Gene) Gene synonyms aliases	L36, eL36
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19p13.3
Summary Summary of gene provided in NCBI Entrez Gene.	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044992	hsa-miR-186-5p	CLASH	23622248
MIRT044707	hsa-miR-320a	CLASH	23622248
MIRT042307	hsa-miR-484	CLASH	23622248
MIRT039808	hsa-miR-615-3p	CLASH	23622248
MIRT457418	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT457417	hsa-miR-205-3p	PAR-CLIP	23592263
MIRT457416	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT457415	hsa-miR-4270	PAR-CLIP	23592263
MIRT457414	hsa-miR-4441	PAR-CLIP	23592263
MIRT457413	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT457412	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT457411	hsa-miR-8085	PAR-CLIP	23592263
MIRT457410	hsa-miR-3127-5p	PAR-CLIP	23592263
MIRT726685	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT726683	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT726684	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT726682	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT457418	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT457417	hsa-miR-205-3p	PAR-CLIP	23592263
MIRT457416	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT457415	hsa-miR-4270	PAR-CLIP	23592263
MIRT457414	hsa-miR-4441	PAR-CLIP	23592263
MIRT457413	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT457412	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT457411	hsa-miR-8085	PAR-CLIP	23592263
MIRT457410	hsa-miR-3127-5p	PAR-CLIP	23592263
MIRT1316763	hsa-miR-2116	CLIP-seq
MIRT1316764	hsa-miR-4677-5p	CLIP-seq
MIRT1316765	hsa-miR-1207-5p	CLIP-seq
MIRT1316766	hsa-miR-1909	CLIP-seq
MIRT1316763	hsa-miR-2116	CLIP-seq
MIRT1316767	hsa-miR-3184	CLIP-seq
MIRT1316768	hsa-miR-3616-3p	CLIP-seq
MIRT1316769	hsa-miR-423-5p	CLIP-seq
MIRT1316770	hsa-miR-4436b-3p	CLIP-seq
MIRT1316764	hsa-miR-4677-5p	CLIP-seq
MIRT1316771	hsa-miR-4728-5p	CLIP-seq
MIRT1316772	hsa-miR-4763-3p	CLIP-seq
MIRT1316765	hsa-miR-1207-5p	CLIP-seq
MIRT1316766	hsa-miR-1909	CLIP-seq
MIRT1316768	hsa-miR-3616-3p	CLIP-seq
MIRT1316770	hsa-miR-4436b-3p	CLIP-seq
MIRT1316772	hsa-miR-4763-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000184	Process	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS
GO:0002181	Process	Cytoplasmic translation	IBA	21873635
GO:0002181	Process	Cytoplasmic translation	IDA	25957688
GO:0003723	Function	RNA binding	HDA	22658674
GO:0003735	Function	Structural constituent of ribosome	IBA	21873635
GO:0003735	Function	Structural constituent of ribosome	NAS	12962325
GO:0005730	Component	Nucleolus	HDA	16791210
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	HDA	16791210
GO:0005829	Component	Cytosol	TAS
GO:0006412	Process	Translation	NAS	12962325
GO:0006413	Process	Translational initiation	TAS
GO:0006614	Process	SRP-dependent cotranslational protein targeting to membrane	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0019083	Process	Viral transcription	TAS
GO:0022625	Component	Cytosolic large ribosomal subunit	HDA	12962325
GO:0022625	Component	Cytosolic large ribosomal subunit	IBA	21873635
GO:0022625	Component	Cytosolic large ribosomal subunit	IDA	25957688
GO:0042788	Component	Polysomal ribosome	IDA	25957688

MIM	HGNC	e!Ensembl
617893	13631	ENSG00000130255

Protein

UniProt ID

Q9Y3U8

Protein name

Large ribosomal subunit protein eL36 (60S ribosomal protein L36)

Protein function

Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25901680, PubMed:25957688, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962

PDB

4UG0 , 4V6X , 5AJ0 , 5LKS , 5T2C , 6IP5 , 6IP6 , 6IP8 , 6LQM , 6LSR , 6LSS , 6LU8 , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6W6L , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6Y6X , 6Z6L , 6Z6M , 6Z6N , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 7BHP , 7F5S , 7OW7 , 7QGG , 7QVP , 7XNX , 7XNY , 8A3D , 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01158	Ribosomal_L36e	4 → 99	Ribosomal protein L36e	Family

Sequence

MALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMEL
LKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD

Sequence length

105

Interactions

View interactions

	KEGG		Reactome
	Ribosome Coronavirus disease - COVID-19		L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Anemia	Anemia, Diamond-Blackfan	rs118204044, rs118204045, rs118204046, rs121918330, rs869320719, rs869312029, rs121918332, rs869320724, rs767094129, rs786205058, rs786205059, rs137853119, rs137853120, rs137853121, rs1384933966 View all (89 more)	28297620

RPL36 (ribosomal protein L36)