Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
25843
Gene name Gene Name - the full gene name approved by the HGNC.
MOB family member 4, phocein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MOB4
Synonyms (NCBI Gene) Gene synonyms aliases
2C4D, CGI-95, MOB1, MOB3, MOBKL3, PHOCN, PREI3
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q33.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alterna
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023746 hsa-miR-1-3p Proteomics;Microarray 18668037
MIRT027305 hsa-miR-101-3p Sequencing 20371350
MIRT031318 hsa-miR-18a-5p Sequencing 20371350
MIRT677739 hsa-miR-3155a HITS-CLIP 23824327
MIRT677738 hsa-miR-3155b HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 18782753, 19156129, 24255178, 24366813, 26496610, 33633399, 33961781
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0005737 Component Cytoplasm ISS
GO:0005794 Component Golgi apparatus IDA 11251078
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609361 17261 ENSG00000115540
Protein
UniProt ID Q9Y3A3
Protein name MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)
Protein function Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytos
PDB 5YF4 , 7K36
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03637 Mob1_phocein 44 209 Mob1/phocein family Family
Sequence
Sequence length 225
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Insomnia Insomnia N/A N/A GWAS
Schizophrenia Schizophrenia N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Neoplasms Associate 35046109
Pancreatic Neoplasms Stimulate 30072378