Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
25840
Gene name Gene Name - the full gene name approved by the HGNC.
Thiol methyltransferase 1A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TMT1A
Synonyms (NCBI Gene) Gene synonyms aliases
AAM-B, AAMB, METTL7A
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001538 hsa-miR-155-5p pSILAC 18668040
MIRT001538 hsa-miR-155-5p Proteomics;Other 18668040
MIRT022187 hsa-miR-124-3p Microarray 18668037
MIRT044794 hsa-miR-320a CLASH 23622248
MIRT517386 hsa-miR-339-5p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32814053
GO:0005576 Component Extracellular region TAS
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005811 Component Lipid droplet IDA
GO:0008168 Function Methyltransferase activity IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618338 24550 ENSG00000185432
Protein
UniProt ID Q9H8H3
Protein name Thiol S-methyltransferase TMT1A (EC 2.1.1.9) (Methyltransferase-like protein 7A) (N6-adenosine-methyltransferase TMT1A) (EC 2.1.1.348) (Protein AAM-B) (Thiol methyltransferase 1A)
Protein function Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endopla
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08241 Methyltransf_11 75 172 Methyltransferase domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the liver. {ECO:0000269|PubMed:37137720}.
Sequence
MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFS
NLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFE
RFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYF
MEHVAAEC
STWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRPHIYG
YAVK
Sequence length 244
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Endometriosis Endometriosis 20864642 ClinVar