Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	25834
Gene name	MGAT4 family member C
Gene symbol	MGAT4C
Synonyms (NCBI Gene)	GNTIVHHGNT-IV-H
Chromosome	12
Chromosome location	12q21.31-q21.32

167

Show/Hide all (167)

miRTarBase ID	miRNA	Experiments	Reference
MIRT607502	hsa-miR-8485	HITS-CLIP	22927820
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	22927820
MIRT608756	hsa-miR-377-3p	HITS-CLIP	22927820
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	22927820
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23313552
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	23313552
MIRT608756	hsa-miR-377-3p	HITS-CLIP	23313552
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	23313552
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23313552
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	23824327
MIRT608756	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	23824327
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT607502	hsa-miR-8485	HITS-CLIP	24906430
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	24906430
MIRT608756	hsa-miR-377-3p	HITS-CLIP	24906430
MIRT607502	hsa-miR-8485	HITS-CLIP	24906430
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	24906430
MIRT607502	hsa-miR-8485	HITS-CLIP	24906430
MIRT607501	hsa-miR-4797-5p	HITS-CLIP	24906430
MIRT514085	hsa-miR-410-3p	PAR-CLIP	20371350
MIRT514084	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT514083	hsa-miR-496	PAR-CLIP	20371350
MIRT514082	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT549533	hsa-miR-4731-3p	PAR-CLIP	21572407
MIRT549532	hsa-miR-4801	PAR-CLIP	21572407
MIRT541528	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT549531	hsa-miR-4719	PAR-CLIP	21572407
MIRT541527	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT541522	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT541521	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541520	hsa-miR-3924	PAR-CLIP	21572407
MIRT541528	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541527	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT541522	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT541521	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541520	hsa-miR-3924	PAR-CLIP	21572407
MIRT541532	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT541531	hsa-miR-300	PAR-CLIP	21572407
MIRT541530	hsa-miR-381-3p	PAR-CLIP	21572407
MIRT541529	hsa-miR-4666a-3p	PAR-CLIP	21572407
MIRT541528	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541527	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT541526	hsa-let-7a-3p	PAR-CLIP	21572407
MIRT541525	hsa-let-7b-3p	PAR-CLIP	21572407
MIRT541524	hsa-let-7f-1-3p	PAR-CLIP	21572407
MIRT541523	hsa-miR-98-3p	PAR-CLIP	21572407
MIRT541522	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT541521	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541520	hsa-miR-3924	PAR-CLIP	21572407
MIRT514085	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT514084	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT514083	hsa-miR-496	PAR-CLIP	23446348
MIRT514082	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT449056	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT449057	hsa-miR-607	PAR-CLIP	22100165
MIRT449055	hsa-miR-1305	PAR-CLIP	22100165
MIRT449054	hsa-miR-335-3p	PAR-CLIP	22100165
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	27418678
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	27418678
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	27418678
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	27418678
MIRT608756	hsa-miR-377-3p	HITS-CLIP	27418678
MIRT608756	hsa-miR-377-3p	HITS-CLIP	27418678
MIRT608756	hsa-miR-377-3p	HITS-CLIP	27418678
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	27418678
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	27418678
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	27418678
MIRT576619	hsa-miR-8485	HITS-CLIP	27418678
MIRT576619	hsa-miR-8485	HITS-CLIP	27418678
MIRT576619	hsa-miR-8485	HITS-CLIP	27418678
MIRT576619	hsa-miR-8485	HITS-CLIP	27418678
MIRT576619	hsa-miR-8485	HITS-CLIP	22927820
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	22927820
MIRT608756	hsa-miR-377-3p	HITS-CLIP	22927820
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	22927820
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23313552
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	23313552
MIRT608756	hsa-miR-377-3p	HITS-CLIP	23313552
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	23313552
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23313552
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT608757	hsa-miR-3614-3p	HITS-CLIP	23824327
MIRT608756	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT671090	hsa-miR-1287-3p	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT576619	hsa-miR-8485	HITS-CLIP	23824327
MIRT576618	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT514085	hsa-miR-410-3p	PAR-CLIP	20371350
MIRT514084	hsa-miR-656-3p	PAR-CLIP	20371350
MIRT514083	hsa-miR-496	PAR-CLIP	20371350
MIRT514082	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT549533	hsa-miR-4731-3p	PAR-CLIP	21572407
MIRT549532	hsa-miR-4801	PAR-CLIP	21572407
MIRT541528	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT549531	hsa-miR-4719	PAR-CLIP	21572407
MIRT541527	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT541522	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT541521	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541520	hsa-miR-3924	PAR-CLIP	21572407
MIRT541528	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541527	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT541522	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT541521	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541520	hsa-miR-3924	PAR-CLIP	21572407
MIRT541532	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT541531	hsa-miR-300	PAR-CLIP	21572407
MIRT541530	hsa-miR-381-3p	PAR-CLIP	21572407
MIRT541529	hsa-miR-4666a-3p	PAR-CLIP	21572407
MIRT541528	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT541527	hsa-miR-4666a-5p	PAR-CLIP	21572407
MIRT541526	hsa-let-7a-3p	PAR-CLIP	21572407
MIRT541525	hsa-let-7b-3p	PAR-CLIP	21572407
MIRT541524	hsa-let-7f-1-3p	PAR-CLIP	21572407
MIRT541523	hsa-miR-98-3p	PAR-CLIP	21572407
MIRT541522	hsa-miR-4789-5p	PAR-CLIP	21572407
MIRT541521	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT541520	hsa-miR-3924	PAR-CLIP	21572407
MIRT514085	hsa-miR-410-3p	PAR-CLIP	23446348
MIRT514084	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT514083	hsa-miR-496	PAR-CLIP	23446348
MIRT514082	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT449056	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT449057	hsa-miR-607	PAR-CLIP	22100165
MIRT449055	hsa-miR-1305	PAR-CLIP	22100165
MIRT449054	hsa-miR-335-3p	PAR-CLIP	22100165

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006487	Process	Protein N-linked glycosylation	IBA
GO:0008375	Function	Acetylglucosaminyltransferase activity	IBA
GO:0008375	Function	Acetylglucosaminyltransferase activity	IEA
GO:0008454	Function	Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	IEA
GO:0008454	Function	Alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	TAS
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0019082	Process	Viral protein processing	TAS
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
607385	30871	ENSG00000182050

Q9UBM8

Protein name

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acet

Protein function

Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04666	Glyco_transf_54	52 → 330		Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas. {ECO:0000269|PubMed:10570912}.

Sequence

MFKFHQMKHIFEILDKMRCLRKRSTVSFLGVLVIFLLFMNLYIEDSYVLEGDKQLIRETS
THQLNSERYVHTFKDLSNFSGAINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLETI
KSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYP
ILDGLKRNYNDPEDRVKFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSKNFLTAIKKV
IASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKN
VIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASLYTNMNVFENYEASKA
YSSVDEYFWGKPPSTGDVFVIVFENPIIIKKIKVNTGTEDRQNDILHHGALDVGENVMPS
KQRRQCSTYLRLGEFKNGNFEMSGVNQKIPFDIHCMRIYVTKTQKEWLIIRSISIWTS

Sequence length

478

Interactions

View interactions

	KEGG		Reactome
	N-Glycan biosynthesis Various types of N-glycan biosynthesis Metabolic pathways		N-Glycan antennae elongation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (11)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ASTROCYTOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATHEROSCLEROSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BELL'S PALSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONOTRUNCAL HEART MALFORMATIONS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SMALL VESSEL STROKE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Glioblastoma	Associate	35456975	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Associate	35456975	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Inflammation	Associate	37308935	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Stimulate	22496589	★★★★★ ★☆☆☆☆ Found in Text Mining only

MGAT4C (MGAT4 family member C)