FBXL2 (F-box and leucine rich repeat protein 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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25827 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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F-box and leucine rich repeat protein 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FBXL2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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FBL2, FBL3 |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p22.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), w |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q9UKC9 | ||||||||||||||||||||||||||||||
| Protein name | F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3) | ||||||||||||||||||||||||||||||
| Protein function | Calcium-activated substrate recognition component of the SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex, SCF(FBXL2), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:2202032 | ||||||||||||||||||||||||||||||
| PDB | 6O60 | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in brain, heart, kidney, liver, lung, pancreas and placenta. {ECO:0000269|PubMed:10531037}. | ||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 423 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||