Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	25825
Gene name	Beta-secretase 2
Gene symbol	BACE2
Synonyms (NCBI Gene)	AEPLCALP56ASP1ASP21BAE2CDA13CEAP1DRAP
Chromosome	21
Chromosome location	21q22.2-q22.3
Summary	This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer`s disease and Down syndrome.

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miRTarBase ID	miRNA	Experiments	Reference
MIRT042142	hsa-miR-484	CLASH	23622248
MIRT720351	hsa-miR-6504-5p	HITS-CLIP	19536157
MIRT720350	hsa-miR-3064-5p	HITS-CLIP	19536157
MIRT720349	hsa-miR-6800-3p	HITS-CLIP	19536157
MIRT720348	hsa-miR-3183	HITS-CLIP	19536157
MIRT720346	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT720347	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT720345	hsa-miR-1237-3p	HITS-CLIP	19536157
MIRT720344	hsa-miR-1248	HITS-CLIP	19536157
MIRT720343	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT720342	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT720340	hsa-miR-4794	HITS-CLIP	19536157
MIRT720341	hsa-miR-664a-5p	HITS-CLIP	19536157
MIRT720339	hsa-miR-149-5p	HITS-CLIP	19536157
MIRT720338	hsa-miR-3182	HITS-CLIP	19536157
MIRT720337	hsa-miR-6821-3p	HITS-CLIP	19536157
MIRT720335	hsa-miR-4448	HITS-CLIP	19536157
MIRT720336	hsa-miR-6861-3p	HITS-CLIP	19536157
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT720334	hsa-miR-3157-3p	HITS-CLIP	19536157
MIRT720333	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT675051	hsa-miR-483-5p	HITS-CLIP	23313552
MIRT675050	hsa-miR-4645-5p	HITS-CLIP	23313552
MIRT675049	hsa-miR-4673	HITS-CLIP	23313552
MIRT675048	hsa-miR-4716-5p	HITS-CLIP	23313552
MIRT693828	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT693827	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT693826	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT693825	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT693824	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT669397	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT693823	hsa-miR-3663-5p	HITS-CLIP	23313552
MIRT693822	hsa-miR-6131	HITS-CLIP	23313552
MIRT675047	hsa-miR-193b-5p	HITS-CLIP	23313552
MIRT675045	hsa-miR-198	HITS-CLIP	23313552
MIRT675044	hsa-miR-6755-3p	HITS-CLIP	23313552
MIRT675042	hsa-miR-197-3p	HITS-CLIP	23313552
MIRT693821	hsa-miR-378a-5p	HITS-CLIP	23313552
MIRT693820	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT693819	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT675041	hsa-miR-3912-5p	HITS-CLIP	23313552
MIRT675039	hsa-miR-5096	HITS-CLIP	23313552
MIRT675038	hsa-miR-1303	HITS-CLIP	23313552
MIRT675051	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT675043	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT675050	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT675049	hsa-miR-4673	HITS-CLIP	23824327
MIRT675048	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT675047	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT675046	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT675045	hsa-miR-198	HITS-CLIP	23824327
MIRT675044	hsa-miR-6755-3p	HITS-CLIP	23824327
MIRT675043	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT675042	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT675041	hsa-miR-3912-5p	HITS-CLIP	23824327
MIRT675040	hsa-miR-3149	HITS-CLIP	23824327
MIRT675039	hsa-miR-5096	HITS-CLIP	23824327
MIRT675038	hsa-miR-1303	HITS-CLIP	23824327
MIRT669400	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT669399	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT669398	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT669397	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669396	hsa-miR-1976	HITS-CLIP	23824327
MIRT669395	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT669394	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT669393	hsa-miR-4279	HITS-CLIP	23824327
MIRT669392	hsa-miR-498	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT457409	hsa-miR-583	PAR-CLIP	23592263
MIRT457408	hsa-miR-3125	PAR-CLIP	23592263
MIRT457407	hsa-miR-3916	PAR-CLIP	23592263
MIRT457406	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT457405	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT457404	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT457403	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT457401	hsa-miR-3153	PAR-CLIP	23592263
MIRT457402	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT457400	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT457399	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT441968	hsa-miR-1277-5p	PAR-CLIP	22100165
MIRT441967	hsa-miR-3651	PAR-CLIP	22100165
MIRT441966	hsa-miR-4778-5p	PAR-CLIP	22100165
MIRT441965	hsa-miR-3607-3p	PAR-CLIP	22100165
MIRT441964	hsa-miR-5189-3p	PAR-CLIP	22100165
MIRT441963	hsa-miR-4662a-5p	PAR-CLIP	22100165
MIRT441962	hsa-miR-3686	PAR-CLIP	22100165
MIRT441960	hsa-miR-2054	PAR-CLIP	22100165
MIRT441961	hsa-miR-1299	PAR-CLIP	22100165
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613302	hsa-miR-141-5p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT613300	hsa-miR-345-3p	HITS-CLIP	28735896
MIRT615721	hsa-miR-3660	HITS-CLIP	28735896
MIRT615721	hsa-miR-3660	HITS-CLIP	28735896
MIRT615721	hsa-miR-3660	HITS-CLIP	28735896
MIRT615721	hsa-miR-3660	HITS-CLIP	28735896
MIRT615721	hsa-miR-3660	HITS-CLIP	28735896
MIRT615721	hsa-miR-3660	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT613296	hsa-miR-4319	HITS-CLIP	28735896
MIRT615720	hsa-miR-4526	HITS-CLIP	28735896
MIRT615720	hsa-miR-4526	HITS-CLIP	28735896
MIRT615720	hsa-miR-4526	HITS-CLIP	28735896
MIRT615720	hsa-miR-4526	HITS-CLIP	28735896
MIRT615720	hsa-miR-4526	HITS-CLIP	28735896
MIRT615720	hsa-miR-4526	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613292	hsa-miR-670-5p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	28735896
MIRT738071	hsa-miR-4308	HITS-CLIP	33718276
MIRT738073	hsa-miR-146b-3p	HITS-CLIP	33718276
MIRT720351	hsa-miR-6504-5p	HITS-CLIP	19536157
MIRT720350	hsa-miR-3064-5p	HITS-CLIP	19536157
MIRT720349	hsa-miR-6800-3p	HITS-CLIP	19536157
MIRT720348	hsa-miR-3183	HITS-CLIP	19536157
MIRT720346	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT720347	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT720345	hsa-miR-1237-3p	HITS-CLIP	19536157
MIRT720344	hsa-miR-1248	HITS-CLIP	19536157
MIRT720343	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT720342	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT720340	hsa-miR-4794	HITS-CLIP	19536157
MIRT720341	hsa-miR-664a-5p	HITS-CLIP	19536157
MIRT720339	hsa-miR-149-5p	HITS-CLIP	19536157
MIRT720338	hsa-miR-3182	HITS-CLIP	19536157
MIRT720337	hsa-miR-6821-3p	HITS-CLIP	19536157
MIRT720335	hsa-miR-4448	HITS-CLIP	19536157
MIRT720336	hsa-miR-6861-3p	HITS-CLIP	19536157
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	19536157
MIRT720334	hsa-miR-3157-3p	HITS-CLIP	19536157
MIRT720333	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT675051	hsa-miR-483-5p	HITS-CLIP	23313552
MIRT675050	hsa-miR-4645-5p	HITS-CLIP	23313552
MIRT675049	hsa-miR-4673	HITS-CLIP	23313552
MIRT675048	hsa-miR-4716-5p	HITS-CLIP	23313552
MIRT693828	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT693827	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT693826	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT693825	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT693824	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT669397	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT693823	hsa-miR-3663-5p	HITS-CLIP	23313552
MIRT693822	hsa-miR-6131	HITS-CLIP	23313552
MIRT675047	hsa-miR-193b-5p	HITS-CLIP	23313552
MIRT675045	hsa-miR-198	HITS-CLIP	23313552
MIRT675044	hsa-miR-6755-3p	HITS-CLIP	23313552
MIRT675042	hsa-miR-197-3p	HITS-CLIP	23313552
MIRT693821	hsa-miR-378a-5p	HITS-CLIP	23313552
MIRT693820	hsa-miR-6843-3p	HITS-CLIP	23313552
MIRT693819	hsa-miR-6848-3p	HITS-CLIP	23313552
MIRT675041	hsa-miR-3912-5p	HITS-CLIP	23313552
MIRT675039	hsa-miR-5096	HITS-CLIP	23313552
MIRT675038	hsa-miR-1303	HITS-CLIP	23313552
MIRT675051	hsa-miR-483-5p	HITS-CLIP	23824327
MIRT675043	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT675050	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT675049	hsa-miR-4673	HITS-CLIP	23824327
MIRT675048	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT675047	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT675046	hsa-miR-6832-5p	HITS-CLIP	23824327
MIRT675045	hsa-miR-198	HITS-CLIP	23824327
MIRT675044	hsa-miR-6755-3p	HITS-CLIP	23824327
MIRT675043	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT675042	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT675041	hsa-miR-3912-5p	HITS-CLIP	23824327
MIRT675040	hsa-miR-3149	HITS-CLIP	23824327
MIRT675039	hsa-miR-5096	HITS-CLIP	23824327
MIRT675038	hsa-miR-1303	HITS-CLIP	23824327
MIRT669400	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT669399	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT669398	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT669397	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669396	hsa-miR-1976	HITS-CLIP	23824327
MIRT669395	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT669394	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT669393	hsa-miR-4279	HITS-CLIP	23824327
MIRT669392	hsa-miR-498	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT615721	hsa-miR-3660	HITS-CLIP	23824327
MIRT615720	hsa-miR-4526	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT613302	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT613301	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT613300	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT613299	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT613298	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT613297	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT613296	hsa-miR-4319	HITS-CLIP	23824327
MIRT613295	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT613294	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT613293	hsa-miR-2277-3p	HITS-CLIP	23824327
MIRT613292	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT613291	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT457409	hsa-miR-583	PAR-CLIP	23592263
MIRT457408	hsa-miR-3125	PAR-CLIP	23592263
MIRT457407	hsa-miR-3916	PAR-CLIP	23592263
MIRT457406	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT457405	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT457404	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT457403	hsa-miR-211-3p	PAR-CLIP	23592263
MIRT457401	hsa-miR-3153	PAR-CLIP	23592263
MIRT457402	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT457400	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT457399	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT441968	hsa-miR-1277-5p	PAR-CLIP	22100165
MIRT441967	hsa-miR-3651	PAR-CLIP	22100165
MIRT441966	hsa-miR-4778-5p	PAR-CLIP	22100165
MIRT441965	hsa-miR-3607-3p	PAR-CLIP	22100165
MIRT441964	hsa-miR-5189-3p	PAR-CLIP	22100165
MIRT441963	hsa-miR-4662a-5p	PAR-CLIP	22100165
MIRT441962	hsa-miR-3686	PAR-CLIP	22100165
MIRT441960	hsa-miR-2054	PAR-CLIP	22100165
MIRT441961	hsa-miR-1299	PAR-CLIP	22100165
MIRT814224	hsa-miR-1206	CLIP-seq
MIRT814225	hsa-miR-1273e	CLIP-seq
MIRT814226	hsa-miR-3150a-5p	CLIP-seq
MIRT814227	hsa-miR-3150b-5p	CLIP-seq
MIRT738072	hsa-miR-3173-5p	CLIP-seq
MIRT814228	hsa-miR-374c	CLIP-seq
MIRT814229	hsa-miR-4682	CLIP-seq
MIRT814230	hsa-miR-548an	CLIP-seq
MIRT814231	hsa-miR-633	CLIP-seq
MIRT814232	hsa-miR-655	CLIP-seq
MIRT738074	hsa-miR-874	CLIP-seq
MIRT738070	hsa-miR-875-3p	CLIP-seq
MIRT738072	hsa-miR-3173-5p	CLIP-seq
MIRT814229	hsa-miR-4682	CLIP-seq
MIRT814231	hsa-miR-633	CLIP-seq
MIRT738074	hsa-miR-874	CLIP-seq
MIRT738070	hsa-miR-875-3p	CLIP-seq
MIRT738072	hsa-miR-3173-5p	CLIP-seq
MIRT738074	hsa-miR-874	CLIP-seq
MIRT738070	hsa-miR-875-3p	CLIP-seq
MIRT738072	hsa-miR-3173-5p	CLIP-seq
MIRT738074	hsa-miR-874	CLIP-seq
MIRT738070	hsa-miR-875-3p	CLIP-seq
MIRT738072	hsa-miR-3173-5p	CLIP-seq
MIRT738074	hsa-miR-874	CLIP-seq
MIRT738070	hsa-miR-875-3p	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SP1	Unknown	15857888

Show/Hide all (30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004190	Function	Aspartic-type endopeptidase activity	IDA	10591213
GO:0004190	Function	Aspartic-type endopeptidase activity	IEA
GO:0005515	Function	Protein binding	IPI	26840340, 32814053
GO:0005768	Component	Endosome	IBA
GO:0005768	Component	Endosome	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005794	Component	Golgi apparatus	IDA	11423558
GO:0005794	Component	Golgi apparatus	IEA
GO:0005802	Component	Trans-Golgi network	IBA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	21907142
GO:0005886	Component	Plasma membrane	IEA
GO:0006508	Process	Proteolysis	IEA
GO:0006508	Process	Proteolysis	NAS	10749877
GO:0006509	Process	Membrane protein ectodomain proteolysis	IBA
GO:0006509	Process	Membrane protein ectodomain proteolysis	IDA	10591213
GO:0006509	Process	Membrane protein ectodomain proteolysis	IEA
GO:0006509	Process	Membrane protein ectodomain proteolysis	IMP	21907142
GO:0008233	Function	Peptidase activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	10749877
GO:0016485	Process	Protein processing	IDA	23754390
GO:0016486	Process	Peptide hormone processing	NAS	10749877
GO:0016787	Function	Hydrolase activity	IEA
GO:0032438	Process	Melanosome organization	IMP	23754390
GO:0033162	Component	Melanosome membrane	IDA	23754390
GO:0042470	Component	Melanosome	IEA
GO:0042593	Process	Glucose homeostasis	IMP	21907142
GO:0042985	Process	Negative regulation of amyloid precursor protein biosynthetic process	IMP	12801932
GO:0050435	Process	Amyloid-beta metabolic process	IBA

MIM	HGNC	e!Ensembl
605668	934	ENSG00000182240

Q9Y5Z0

Protein name

Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-as

Protein function

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-

PDB

2EWY , 3ZKG , 3ZKI , 3ZKM , 3ZKN , 3ZKQ , 3ZKS , 3ZKX , 3ZL7 , 3ZLQ , 4BEL , 4BFB , 6JSZ , 6UJ0 , 6UJ1 , 7D5B , 7D5U , 7F1G , 7N4N

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00026	Asp	91 → 431	Eukaryotic aspartyl protease	Family

Tissue specificity

TISSUE SPECIFICITY: Brain. Present in neurons within the hippocampus, frontal cortex and temporal cortex (at protein level). Expressed at low levels in most peripheral tissues and at higher levels in colon, kidney, pancreas, placenta, prostate, stomach an

Sequence

MGALARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPGTPAERHADGL
ALALEPALASPAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
TPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATI
FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISI
YLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD
RAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCG
AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK

Sequence length

518

Interactions

View interactions

	KEGG
	Alzheimer disease

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
BACE2-related disorder	Benign; Likely benign	rs2252576, rs1046210, rs149345353, rs369963511, rs144644942, rs376619639, rs73368323, rs6517660	RCV003974551 RCV003984667 RCV003922292 RCV003956850 RCV003910752 RCV003960501 RCV003972882 RCV003972883
Cervical cancer	Benign	rs73368323	RCV005908398
Sarcoma	Benign	rs73368323	RCV005908399
Uterine corpus endometrial carcinoma	Benign	rs73368323	RCV005908400

Show/Hide Text Mining Associations (19)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
AA amyloidosis	Associate	31270419
Alzheimer Disease	Associate	10931940, 15492223, 24462566, 31270419, 32566665, 33633844
Alzheimer Disease	Stimulate	22074738
Alzheimer Disease	Inhibit	32647257
Carcinoma Ovarian Epithelial	Inhibit	31158220
Cognitive Dysfunction	Associate	22911757, 31270419
Dementia	Associate	24462566, 32647257
Diabetes Gestational	Associate	36313769
Diabetes Mellitus Type 2	Inhibit	24905913
Down Syndrome	Associate	24462566, 28648597, 32647257, 33633844
Frontotemporal Dementia	Stimulate	22074738
Heart Defects Congenital	Associate	28648597
Heredodegenerative Disorders Nervous System	Associate	22074738
Melanoma	Stimulate	33601055, 36320118
Neoplasms	Associate	24553122
Neoplasms	Stimulate	33601055
Neurodegenerative Diseases	Associate	22074738
Pigmentation Disorders	Associate	33601055
Pre Eclampsia	Stimulate	25031267

BACE2 (beta-secretase 2)