Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	25822
Gene name Gene Name - the full gene name approved by the HGNC.	DnaJ heat shock protein family (Hsp40) member B5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DNAJB5
Synonyms (NCBI Gene) Gene synonyms aliases	Hsc40
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9p13.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family me

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miRTarBase ID	miRNA	Experiments	Reference
MIRT024402	hsa-miR-215-5p	Microarray	19074876
MIRT026797	hsa-miR-192-5p	Microarray	19074876
MIRT044713	hsa-miR-320a	CLASH	23622248
MIRT658979	hsa-miR-129-1-3p	HITS-CLIP	19536157
MIRT658978	hsa-miR-129-2-3p	HITS-CLIP	19536157
MIRT658977	hsa-miR-3622a-3p	HITS-CLIP	19536157
MIRT658976	hsa-miR-3622b-3p	HITS-CLIP	19536157
MIRT658975	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT658973	hsa-miR-4750-3p	HITS-CLIP	19536157
MIRT658972	hsa-miR-6859-3p	HITS-CLIP	19536157
MIRT658971	hsa-miR-6846-3p	HITS-CLIP	19536157
MIRT658970	hsa-miR-623	HITS-CLIP	19536157
MIRT658969	hsa-miR-204-5p	HITS-CLIP	19536157
MIRT658968	hsa-miR-211-5p	HITS-CLIP	19536157
MIRT658967	hsa-miR-4755-5p	HITS-CLIP	19536157
MIRT658966	hsa-miR-5006-3p	HITS-CLIP	19536157
MIRT658965	hsa-miR-4446-5p	HITS-CLIP	19536157
MIRT658979	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT658978	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT658977	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT658976	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT658975	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT658974	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT668705	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT658973	hsa-miR-4750-3p	HITS-CLIP	23824327
MIRT658972	hsa-miR-6859-3p	HITS-CLIP	23824327
MIRT658971	hsa-miR-6846-3p	HITS-CLIP	23824327
MIRT658970	hsa-miR-623	HITS-CLIP	23824327
MIRT658969	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT658968	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT668704	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT668703	hsa-miR-1200	HITS-CLIP	23824327
MIRT658967	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT658966	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT658965	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT658979	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT658978	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT658977	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT658976	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT658975	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT658974	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT658973	hsa-miR-4750-3p	HITS-CLIP	23824327
MIRT658972	hsa-miR-6859-3p	HITS-CLIP	23824327
MIRT658971	hsa-miR-6846-3p	HITS-CLIP	23824327
MIRT658970	hsa-miR-623	HITS-CLIP	23824327
MIRT658969	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT658968	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT658967	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT658966	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT658965	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT658979	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT658978	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT658977	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT658976	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT658975	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT658974	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT668705	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT658973	hsa-miR-4750-3p	HITS-CLIP	23824327
MIRT658972	hsa-miR-6859-3p	HITS-CLIP	23824327
MIRT658971	hsa-miR-6846-3p	HITS-CLIP	23824327
MIRT658970	hsa-miR-623	HITS-CLIP	23824327
MIRT658969	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT658968	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT668704	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT668703	hsa-miR-1200	HITS-CLIP	23824327
MIRT658967	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT658966	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT658965	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT658979	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT658978	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT658977	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT658976	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT658975	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT658974	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT658973	hsa-miR-4750-3p	HITS-CLIP	23824327
MIRT658972	hsa-miR-6859-3p	HITS-CLIP	23824327
MIRT658971	hsa-miR-6846-3p	HITS-CLIP	23824327
MIRT658970	hsa-miR-623	HITS-CLIP	23824327
MIRT658969	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT658968	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT658967	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT658966	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT658965	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT1978065	hsa-miR-4651	CLIP-seq
MIRT1978066	hsa-miR-608	CLIP-seq
MIRT2213580	hsa-miR-1224-3p	CLIP-seq
MIRT2213581	hsa-miR-1261	CLIP-seq
MIRT2213582	hsa-miR-1297	CLIP-seq
MIRT2213583	hsa-miR-216b	CLIP-seq
MIRT2213584	hsa-miR-26a	CLIP-seq
MIRT2213585	hsa-miR-26b	CLIP-seq
MIRT2213586	hsa-miR-300	CLIP-seq
MIRT2213587	hsa-miR-3126-3p	CLIP-seq
MIRT2213588	hsa-miR-3138	CLIP-seq
MIRT2213589	hsa-miR-320e	CLIP-seq
MIRT2213590	hsa-miR-323b-5p	CLIP-seq
MIRT2213591	hsa-miR-342-5p	CLIP-seq
MIRT2213592	hsa-miR-3609	CLIP-seq
MIRT2213593	hsa-miR-361-3p	CLIP-seq
MIRT2213594	hsa-miR-3622b-5p	CLIP-seq
MIRT2213595	hsa-miR-3675-3p	CLIP-seq
MIRT2213596	hsa-miR-3675-5p	CLIP-seq
MIRT2213597	hsa-miR-377	CLIP-seq
MIRT2213598	hsa-miR-381	CLIP-seq
MIRT2213599	hsa-miR-3913-3p	CLIP-seq
MIRT2213600	hsa-miR-3973	CLIP-seq
MIRT2213601	hsa-miR-412	CLIP-seq
MIRT2213602	hsa-miR-4438	CLIP-seq
MIRT2213603	hsa-miR-4465	CLIP-seq
MIRT2213604	hsa-miR-450b-3p	CLIP-seq
MIRT1978065	hsa-miR-4651	CLIP-seq
MIRT2213605	hsa-miR-4654	CLIP-seq
MIRT2213606	hsa-miR-4664-5p	CLIP-seq
MIRT2213607	hsa-miR-4666-3p	CLIP-seq
MIRT2213608	hsa-miR-4684-5p	CLIP-seq
MIRT2213609	hsa-miR-4713-3p	CLIP-seq
MIRT2213610	hsa-miR-4769-5p	CLIP-seq
MIRT2213611	hsa-miR-4787-5p	CLIP-seq
MIRT2213612	hsa-miR-4789-5p	CLIP-seq
MIRT2213613	hsa-miR-490-5p	CLIP-seq
MIRT2213614	hsa-miR-5095	CLIP-seq
MIRT2213615	hsa-miR-510	CLIP-seq
MIRT2213616	hsa-miR-520g	CLIP-seq
MIRT2213617	hsa-miR-520h	CLIP-seq
MIRT2213618	hsa-miR-539	CLIP-seq
MIRT2213619	hsa-miR-543	CLIP-seq
MIRT2213620	hsa-miR-548ah	CLIP-seq
MIRT2213621	hsa-miR-555	CLIP-seq
MIRT2213622	hsa-miR-562	CLIP-seq
MIRT1978066	hsa-miR-608	CLIP-seq
MIRT2213623	hsa-miR-638	CLIP-seq
MIRT2213624	hsa-miR-769-3p	CLIP-seq
MIRT2213580	hsa-miR-1224-3p	CLIP-seq
MIRT2517406	hsa-miR-1291	CLIP-seq
MIRT2517407	hsa-miR-129-3p	CLIP-seq
MIRT2517408	hsa-miR-146b-3p	CLIP-seq
MIRT2517409	hsa-miR-1972	CLIP-seq
MIRT2517410	hsa-miR-204	CLIP-seq
MIRT2517411	hsa-miR-211	CLIP-seq
MIRT2517412	hsa-miR-2278	CLIP-seq
MIRT2517413	hsa-miR-296-5p	CLIP-seq
MIRT2517414	hsa-miR-3189-5p	CLIP-seq
MIRT2517415	hsa-miR-339-5p	CLIP-seq
MIRT2517416	hsa-miR-3529	CLIP-seq
MIRT2213593	hsa-miR-361-3p	CLIP-seq
MIRT2517417	hsa-miR-3614-3p	CLIP-seq
MIRT2517418	hsa-miR-374c	CLIP-seq
MIRT2517419	hsa-miR-379	CLIP-seq
MIRT2517420	hsa-miR-3938	CLIP-seq
MIRT2517421	hsa-miR-4290	CLIP-seq
MIRT2517422	hsa-miR-4324	CLIP-seq
MIRT2517423	hsa-miR-4451	CLIP-seq
MIRT2517424	hsa-miR-4493	CLIP-seq
MIRT2517425	hsa-miR-4502	CLIP-seq
MIRT2517426	hsa-miR-4650-3p	CLIP-seq
MIRT2517427	hsa-miR-4650-5p	CLIP-seq
MIRT2517428	hsa-miR-4777-3p	CLIP-seq
MIRT2517429	hsa-miR-4780	CLIP-seq
MIRT2517430	hsa-miR-483-3p	CLIP-seq
MIRT2517431	hsa-miR-544b	CLIP-seq
MIRT2517432	hsa-miR-655	CLIP-seq
MIRT2517433	hsa-miR-670	CLIP-seq
MIRT2517434	hsa-miR-875-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	18457437, 21078624, 22810586, 23414517
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA	21231916
GO:0006986	Process	Response to unfolded protein	IEP	10570961
GO:0051082	Function	Unfolded protein binding	IBA	21873635
GO:0051085	Process	Chaperone cofactor-dependent protein refolding	IBA	21873635
GO:0051087	Function	Chaperone binding	IBA	21873635
GO:0051087	Function	Chaperone binding	IPI	21231916

MIM	HGNC	e!Ensembl
611328	14887	ENSG00000137094

Protein

UniProt ID

O75953

Protein name

DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00226	DnaJ	4 → 65	DnaJ domain	Domain
PF01556	DnaJ_C	171 → 330	DnaJ C terminal domain	Domain

Sequence

MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKK
RGLYDQYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRP
FSGFDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLE
EIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPA
DIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGT
VKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS

Sequence length

348

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Peripheral neuropathy	Peripheral Neuropathy	rs28940294, rs137852972, rs104894715, rs121918312, rs137852667, rs2101018240, rs149782619, rs397514490, rs62636502, rs797044802, rs879253752, rs879253869, rs777219451, rs538412810, rs759785462 View all (6 more)	26257172

DNAJB5 (DnaJ heat shock protein family (Hsp40) member B5)