Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
257194
Gene name Gene Name - the full gene name approved by the HGNC.
Neuronal growth regulator 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NEGR1
Synonyms (NCBI Gene) Gene synonyms aliases
DMML2433, IGLON4, KILON, Ntra
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p31.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT722855 hsa-miR-6819-3p HITS-CLIP 19536157
MIRT722854 hsa-miR-6877-3p HITS-CLIP 19536157
MIRT722853 hsa-miR-4528 HITS-CLIP 19536157
MIRT722852 hsa-miR-4742-3p HITS-CLIP 19536157
MIRT722851 hsa-miR-2114-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21982860, 27940359
GO:0005576 Component Extracellular region TAS
GO:0005886 Component Plasma membrane TAS
GO:0007626 Process Locomotory behavior IEA
GO:0007631 Process Feeding behavior IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613173 17302 ENSG00000172260
Protein
UniProt ID Q7Z3B1
Protein name Neuronal growth regulator 1 (IgLON family member 4)
Protein function May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).
PDB 6DLD , 6U6T
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07679 I-set 43 135 Immunoglobulin I-set domain Domain
PF13927 Ig_3 138 207 Domain
PF13927 Ig_3 224 301 Domain
Sequence
Sequence length 354
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Cell adhesion molecules   Post-translational modification: synthesis of GPI-anchored proteins
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)
19079261
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
31374203
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 30804558, 29942085 ClinVar
Coenzyme Q10 Deficiency Coenzyme Q10 Deficiency GWAS
Systemic lupus erythematosus Systemic lupus erythematosus GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Anorexia Nervosa Associate 35703085
Asthma Associate 20816195
Breast Neoplasms Associate 24648515, 26544852
Cell Transformation Neoplastic Associate 24648515
Cerebral Infarction Associate 33000228
Delayed Emergence from Anesthesia Associate 22179955
Depressive Disorder Associate 36634823
Diabetes Mellitus Associate 25370040
Diabetes Mellitus Type 2 Associate 34391409, 40141237
Diabetes Mellitus Type 2 Inhibit 37935012