Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
257194
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Neuronal growth regulator 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
NEGR1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
DMML2433, IGLON4, KILON, Ntra |
Chromosome
Chromosome number
|
1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1p31.1 |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Obesity |
Obesity |
rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs193922650, rs193922685, rs193922687, rs751160202, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829 View all (27 more) |
19079261 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
31374203 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Mental depression |
Major Depressive Disorder |
|
30804558, 29942085 |
ClinVar |
Coenzyme Q10 Deficiency |
Coenzyme Q10 Deficiency |
|
|
GWAS |
Systemic lupus erythematosus |
Systemic lupus erythematosus |
|
|
GWAS |
Metabolic Syndrome |
Metabolic Syndrome |
|
|
GWAS |
Neuroblastoma |
Neuroblastoma |
Loss of SNAI2 function reduces self-renewal, 3D invasion as well as metastatic spread in vivo, while strongly sensitizing neuroblastoma cells to RA-induced growth inhibition. |
|
GWAS, CBGDA |
Hypertension |
Hypertension |
|
|
GWAS |
Insomnia |
Insomnia |
|
|
GWAS |
Colorectal Cancer |
Colorectal Cancer |
In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. |
|
GWAS, CBGDA |
Restless Legs Syndrome |
Restless Legs Syndrome |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Anorexia Nervosa |
Associate
|
35703085 |
Asthma |
Associate
|
20816195 |
Breast Neoplasms |
Associate
|
24648515, 26544852 |
Cell Transformation Neoplastic |
Associate
|
24648515 |
Cerebral Infarction |
Associate
|
33000228 |
Delayed Emergence from Anesthesia |
Associate
|
22179955 |
Depressive Disorder |
Associate
|
36634823 |
Diabetes Mellitus |
Associate
|
25370040 |
Diabetes Mellitus Type 2 |
Associate
|
34391409, 40141237 |
Diabetes Mellitus Type 2 |
Inhibit
|
37935012 |
Fractures Bone |
Associate
|
35090337 |
Glucocorticoid Receptor Deficiency |
Associate
|
30026463 |
Kidney Neoplasms |
Inhibit
|
33299884 |
Malformations of Cortical Development Group I |
Associate
|
33000228 |
Neoplasms |
Inhibit
|
16115914 |
Neoplasms Adipose Tissue |
Associate
|
19692490, 37935012 |
Neuroblastoma |
Associate
|
21624008 |
Neurodegenerative Diseases |
Associate
|
32396724 |
Obesity |
Associate
|
19079261, 19164386, 19692490, 19910938, 20520848, 21796137, 23349760, 23375129, 23539184, 23563609, 23820787, 23950976, 23950990, 25072390, 25370040, 28428959, 31888951, 32419576, 33859285, 34391409, 35090337 View all (6 more) |
Obesity Abdominal |
Inhibit
|
28428959 |
Osteoporosis |
Associate
|
35090337 |
Osteoporotic Fractures |
Associate
|
35090337 |
Ovarian Neoplasms |
Associate
|
16115914 |
Overweight |
Associate
|
23347264, 32419576 |
Parkinson Disease |
Associate
|
36634823 |
Polycystic Ovary Syndrome |
Associate
|
21283731 |
Weight Loss |
Associate
|
22179955 |
|