C10orf67 (chromosome 10 open reading frame 67)

Gene

• Entrez ID: 256815
• Gene name: Chromosome 10 open reading frame 67
• Gene symbol: C10orf67
• Synonyms (NCBI Gene): C10orf115, LINC01552
• Chromosome: 10
• Chromosome location: 10p12.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT620162	hsa-miR-8485	HITS-CLIP	23824327
MIRT620161	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT620160	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT663827	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT620159	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620158	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT620157	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT620156	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT620155	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT620154	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT620153	hsa-miR-3652	HITS-CLIP	23824327
MIRT620152	hsa-miR-4430	HITS-CLIP	23824327
MIRT620151	hsa-miR-4505	HITS-CLIP	23824327
MIRT620150	hsa-miR-5787	HITS-CLIP	23824327
MIRT620149	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT620148	hsa-miR-4535	HITS-CLIP	23824327
MIRT620162	hsa-miR-8485	HITS-CLIP	23824327
MIRT620161	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT620160	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620159	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620158	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT620157	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT620156	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT620155	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT620154	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT620153	hsa-miR-3652	HITS-CLIP	23824327
MIRT620152	hsa-miR-4430	HITS-CLIP	23824327
MIRT620151	hsa-miR-4505	HITS-CLIP	23824327
MIRT620150	hsa-miR-5787	HITS-CLIP	23824327
MIRT620149	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT620148	hsa-miR-4535	HITS-CLIP	23824327
MIRT551344	hsa-miR-582-3p	PAR-CLIP	21572407
MIRT517624	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517623	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517622	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517624	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517623	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517622	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517624	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT517623	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT517622	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT620162	hsa-miR-8485	HITS-CLIP	23824327
MIRT620161	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT620160	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT663827	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT620159	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620158	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT620157	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT620156	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT620155	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT620154	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT620153	hsa-miR-3652	HITS-CLIP	23824327
MIRT620152	hsa-miR-4430	HITS-CLIP	23824327
MIRT620151	hsa-miR-4505	HITS-CLIP	23824327
MIRT620150	hsa-miR-5787	HITS-CLIP	23824327
MIRT620149	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT620148	hsa-miR-4535	HITS-CLIP	23824327
MIRT620162	hsa-miR-8485	HITS-CLIP	23824327
MIRT620161	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT620160	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620159	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620158	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT620157	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT620156	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT620155	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT620154	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT620153	hsa-miR-3652	HITS-CLIP	23824327
MIRT620152	hsa-miR-4430	HITS-CLIP	23824327
MIRT620151	hsa-miR-4505	HITS-CLIP	23824327
MIRT620150	hsa-miR-5787	HITS-CLIP	23824327
MIRT620149	hsa-miR-6842-3p	HITS-CLIP	23824327
MIRT620148	hsa-miR-4535	HITS-CLIP	23824327
MIRT551344	hsa-miR-582-3p	PAR-CLIP	21572407
MIRT517624	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517623	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517622	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517624	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT517623	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT517622	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT517624	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT517623	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT517622	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT829089	hsa-miR-1206	CLIP-seq
MIRT829090	hsa-miR-1207-3p	CLIP-seq
MIRT829091	hsa-miR-128	CLIP-seq
MIRT829092	hsa-miR-1295	CLIP-seq
MIRT829093	hsa-miR-138	CLIP-seq
MIRT829094	hsa-miR-155	CLIP-seq
MIRT829095	hsa-miR-181a	CLIP-seq
MIRT829096	hsa-miR-181b	CLIP-seq
MIRT829097	hsa-miR-181c	CLIP-seq
MIRT829098	hsa-miR-181d	CLIP-seq
MIRT829099	hsa-miR-2114	CLIP-seq
MIRT829100	hsa-miR-214	CLIP-seq
MIRT829101	hsa-miR-221	CLIP-seq
MIRT829102	hsa-miR-222	CLIP-seq
MIRT829103	hsa-miR-2276	CLIP-seq
MIRT829104	hsa-miR-296-3p	CLIP-seq
MIRT829105	hsa-miR-3115	CLIP-seq
MIRT829106	hsa-miR-3150b-3p	CLIP-seq
MIRT829107	hsa-miR-3607-3p	CLIP-seq
MIRT829108	hsa-miR-3619-5p	CLIP-seq
MIRT829109	hsa-miR-3664-3p	CLIP-seq
MIRT829110	hsa-miR-3667-5p	CLIP-seq
MIRT829111	hsa-miR-3668	CLIP-seq
MIRT829112	hsa-miR-3686	CLIP-seq
MIRT829113	hsa-miR-3929	CLIP-seq
MIRT829114	hsa-miR-4257	CLIP-seq
MIRT829115	hsa-miR-4261	CLIP-seq
MIRT829116	hsa-miR-4262	CLIP-seq
MIRT829117	hsa-miR-4419b	CLIP-seq
MIRT829118	hsa-miR-4433	CLIP-seq
MIRT829119	hsa-miR-4446-5p	CLIP-seq
MIRT829120	hsa-miR-4459	CLIP-seq
MIRT829121	hsa-miR-4478	CLIP-seq
MIRT829122	hsa-miR-4514	CLIP-seq
MIRT829123	hsa-miR-4645-5p	CLIP-seq
MIRT829124	hsa-miR-4649-3p	CLIP-seq
MIRT829125	hsa-miR-4673	CLIP-seq
MIRT829126	hsa-miR-4687-3p	CLIP-seq
MIRT829127	hsa-miR-4692	CLIP-seq
MIRT829128	hsa-miR-4695-5p	CLIP-seq
MIRT829129	hsa-miR-4717-5p	CLIP-seq
MIRT829130	hsa-miR-4722-5p	CLIP-seq
MIRT829131	hsa-miR-4732-5p	CLIP-seq
MIRT829132	hsa-miR-4755-3p	CLIP-seq
MIRT829133	hsa-miR-4755-5p	CLIP-seq
MIRT829134	hsa-miR-4768-3p	CLIP-seq
MIRT829135	hsa-miR-4784	CLIP-seq
MIRT829136	hsa-miR-485-5p	CLIP-seq
MIRT829137	hsa-miR-494	CLIP-seq
MIRT829138	hsa-miR-510	CLIP-seq
MIRT829139	hsa-miR-512-5p	CLIP-seq
MIRT829140	hsa-miR-543	CLIP-seq
MIRT829141	hsa-miR-548v	CLIP-seq
MIRT829142	hsa-miR-761	CLIP-seq
MIRT829118	hsa-miR-4433	CLIP-seq
MIRT829090	hsa-miR-1207-3p	CLIP-seq
MIRT829103	hsa-miR-2276	CLIP-seq
MIRT1945471	hsa-miR-1207-5p	CLIP-seq
MIRT829099	hsa-miR-2114	CLIP-seq
MIRT1945472	hsa-miR-224	CLIP-seq
MIRT1945473	hsa-miR-3065-3p	CLIP-seq
MIRT829109	hsa-miR-3664-3p	CLIP-seq
MIRT829113	hsa-miR-3929	CLIP-seq
MIRT829117	hsa-miR-4419b	CLIP-seq
MIRT829118	hsa-miR-4433	CLIP-seq
MIRT829120	hsa-miR-4459	CLIP-seq
MIRT829121	hsa-miR-4478	CLIP-seq
MIRT829124	hsa-miR-4649-3p	CLIP-seq
MIRT829128	hsa-miR-4695-5p	CLIP-seq
MIRT1945474	hsa-miR-4728-3p	CLIP-seq
MIRT1945475	hsa-miR-4763-3p	CLIP-seq
MIRT829134	hsa-miR-4768-3p	CLIP-seq
MIRT829136	hsa-miR-485-5p	CLIP-seq
MIRT1945476	hsa-miR-509-3p	CLIP-seq
MIRT829138	hsa-miR-510	CLIP-seq
MIRT829139	hsa-miR-512-5p	CLIP-seq
MIRT1945477	hsa-miR-767-5p	CLIP-seq
MIRT829118	hsa-miR-4433	CLIP-seq
MIRT2183838	hsa-miR-4689	CLIP-seq
MIRT829130	hsa-miR-4722-5p	CLIP-seq
MIRT2384942	hsa-miR-1184	CLIP-seq
MIRT2384943	hsa-miR-1343	CLIP-seq
MIRT2384944	hsa-miR-3192	CLIP-seq
MIRT829118	hsa-miR-4433	CLIP-seq
MIRT2384945	hsa-miR-661	CLIP-seq
MIRT2487547	hsa-miR-3177-5p	CLIP-seq
MIRT2487548	hsa-miR-3187-3p	CLIP-seq
MIRT2487549	hsa-miR-4529-5p	CLIP-seq
MIRT2487550	hsa-miR-520a-5p	CLIP-seq
MIRT2487551	hsa-miR-525-5p	CLIP-seq
MIRT2487547	hsa-miR-3177-5p	CLIP-seq
MIRT2487548	hsa-miR-3187-3p	CLIP-seq
MIRT2676290	hsa-miR-339-5p	CLIP-seq
MIRT2676291	hsa-miR-4421	CLIP-seq
MIRT2487549	hsa-miR-4529-5p	CLIP-seq
MIRT2676292	hsa-miR-593	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	27812135, 32296183
GO:0005739	Component	Mitochondrion	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IYJ2
• Protein name: Uncharacterized protein C10orf67, mitochondrial
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15821	DUF4709	70 → 179	Domain of unknown function (DUF4709)	Family
  PF15852	DUF4724	458 → 547	Domain of unknown function (DUF4724)	Family

• Sequence:

  MMALVRDRRAHYVMSIVIRWVHCFSSSLRGTFGTRWEAMKAKATELRVCCARRKREAREF
  KPPQMRGSTRLNISDDLKIGFFSTDHATQTDSSEILSVKELSSSTQKLAQMMKSLQVDFG
  FLKQLLQLKFEDRLKEESLSLFTILHDRILEIEKHYQQNEDKMRKSFNQQLADAIAVIKG
  MYQQFFEVEEENVSLQDASTVKTNILLRKLKEKEEVIKELKEELDQYKDFGFHKMESFAK
  ETSSPKSNLEKENLEYKVENERLLQIISELEEEIQINLKENSGLEDELISMKEMAEKDHK
  TIQKLMDSRDRLREELHYEKSLVQDVINKQKEDKEMRKKYGSLSVKVARSAKGREASLSP
  WPKSPPSTTALRPHSATMSVSSAGAQKAKMPKKALKEDQAVVEDKHGLESQIEALKANLE
  NEKKKVERFRKEADRLNKSWEKRFFILRNSFHVLKNEMFTRHTLFRQFAVLADTSFNYIK
  VKPLLVQSRTTMTAISSSSHCTSSIDGKHVDVVSDQAALQLSPKGKLSESPKEESLEEPS
  MRQSSPAETVD

• Sequence length: 551

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Pancreatic agenesis 2	Pathogenic	rs2492731216	RCV003126284	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SYSTEMIC LUPUS ERYTHEMATOSUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Sarcoidosis	Associate	22972473	★☆☆☆☆ Found in Text Mining only