Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
256536
Gene name Gene Name - the full gene name approved by the HGNC.
Transcription elongation regulator 1 like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TCERG1L
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q26.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT1415914 hsa-miR-1 CLIP-seq
MIRT1415915 hsa-miR-1178 CLIP-seq
MIRT1415916 hsa-miR-128 CLIP-seq
MIRT1415917 hsa-miR-206 CLIP-seq
MIRT1415918 hsa-miR-27a CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003712 Function Transcription coregulator activity IBA 21873635
GO:0005634 Component Nucleus IBA 21873635
GO:0006355 Process Regulation of transcription, DNA-templated IEA
GO:0070063 Function RNA polymerase binding IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620498 23533 ENSG00000176769
Protein
UniProt ID Q5VWI1
Protein name Transcription elongation regulator 1-like protein
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01846 FF 452 500 FF domain Family
PF01846 FF 518 567 FF domain Family
Sequence
MQAGARFQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPP
VLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGH
SPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPE
ESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAI
ATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPAL
MLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNP
TMHLSVWEKPMDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNR
TEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIV
FDPRYLLLNSEERKQIFEQF
VKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKE
FAEKYGRDQRFRLVQKRKDQEHFFNQF
ILILKKRDKENRLRLRKMR
Sequence length 586
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
21278247
Colorectal neoplasms Colorectal Neoplasms rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049
View all (1682 more)
21278247
Lung carcinoma Carcinoma of lung rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355
View all (44 more)
28604730
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Crohn Disease Crohn Disease GWAS
Colorectal Cancer Colorectal Cancer In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. GWAS, CBGDA
Glioblastoma Glioblastoma CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 37082886
Adenoma Associate 22238052
Attention Deficit Disorder with Hyperactivity Associate 20732627
Colorectal Neoplasms Associate 22238052, 23321599
Insulin Resistance Associate 22791750
Neoplasms Inhibit 22238052
Neoplasms Associate 23321599
Oculocerebrorenal Syndrome Associate 37082886
Otitis Media Associate 24499112
Pulmonary Disease Chronic Obstructive Associate 29313708