Gene Gene information from NCBI Gene database.
Entrez ID 256051
Gene name Zinc finger protein 549
Gene symbol ZNF549
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19q13.43
miRNA miRNA information provided by mirtarbase database.
403
miRTarBase ID miRNA Experiments Reference
MIRT022614 hsa-miR-124-3p Microarray 18668037
MIRT029426 hsa-miR-26b-5p Microarray 19088304
MIRT036132 hsa-miR-1296-5p CLASH 23622248
MIRT720401 hsa-miR-4797-5p HITS-CLIP 19536157
MIRT720400 hsa-miR-3664-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620720 26632 ENSG00000121406
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6P9A3
Protein name Zinc finger protein 549
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 26 67 KRAB box Family
PF00096 zf-C2H2 275 298 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 304 326 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 332 355 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 361 383 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 389 411 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 417 439 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 445 467 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 473 495 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 529 551 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 557 579 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 613 635 Zinc finger, C2H2 type Domain
Sequence
MAEAALVITPQIPMVTEEFVKPSQGHVTFEDIAVYFSQEEWGLLDEAQRCLYHDVMLENF
SLMASVG
CLHGIEAEEAPSEQTLSAQGVSQARTPKLGPSIPNAHSCEMCILVMKDILYLS
EHQGTLPWQKPYTSVASGKWFSFGSNLQQHQNQDSGEKHIRKEESSALLLNSCKIPLSDN
LFPCKDVEKDFPTILGLLQHQTTHSRQEYAHRSRETFQQRRYKCEQVFNEKVHVTEHQRV
HTGEKAYKRREYGKSLNSKYLFVEHQRTHNAEKPYVCNICGKSFLHKQTLVGHQQRIHTR
ERSYVCIECGKSLSSKYSLVEHQRTHNGEKPYVCNVCGKSFRHKQTFVGHQQRIHTGERP
YVCMECGKSFIHSYDRIRHQRVHTGEGAYQCSECGKSFIYKQSLLDHHRIHTGERPYECK
ECGKAFIHKKRLLEHQRIH
TGEKPYVCIICGKSFIRSSDYMRHQRIHTGERAYECSDCGK
AFISKQTLLKHHKIH
TRERPYECSECGKGFYLEVKLLQHQRIHTREQLCECNECGKVFSH
QKRLLEHQKVH
TGEKPCECSECGKCFRHRTSLIQHQKVHSGERPYNCTACEKAFIYKNKL
VEHQRIHTGEKPYECGKCGKAFNKRYSLVRHQKVHITEEP
Sequence length 640
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ANDROGENETIC ALOPECIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Adenocarcinoma of Lung Associate 32559455
★☆☆☆☆
Found in Text Mining only
Colonic Neoplasms Inhibit 33028966
★☆☆☆☆
Found in Text Mining only
Lung Neoplasms Associate 32559455
★☆☆☆☆
Found in Text Mining only
Nasopharyngeal Carcinoma Associate 28716111
★☆☆☆☆
Found in Text Mining only
Neoplasms Inhibit 33028966
★☆☆☆☆
Found in Text Mining only
Pulmonary Disease Chronic Obstructive Inhibit 32559455
★☆☆☆☆
Found in Text Mining only