NPNT (nephronectin)

Gene

• Entrez ID: 255743
• Gene name: Nephronectin
• Gene symbol: NPNT
• Synonyms (NCBI Gene): EGFL6L, POEM
• Chromosome: 4
• Chromosome location: 4q24

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005422	hsa-miR-378a-3p	GFP reporter assay, Luciferase reporter assay, Western blot	19844573
MIRT005422	hsa-miR-378a-3p	GFP reporter assay, Luciferase reporter assay, Western blot	19844573
MIRT005422	hsa-miR-378a-3p	GFP reporter assay, Luciferase reporter assay, Western blot	19844573
MIRT026404	hsa-miR-192-5p	Microarray	19074876
MIRT039335	hsa-miR-425-5p	CLASH	23622248
MIRT572622	hsa-miR-3923	PAR-CLIP	20371350
MIRT572621	hsa-miR-4661-3p	PAR-CLIP	20371350
MIRT572620	hsa-miR-1323	PAR-CLIP	20371350
MIRT572619	hsa-miR-548o-3p	PAR-CLIP	20371350
MIRT572618	hsa-miR-325	PAR-CLIP	20371350
MIRT572617	hsa-miR-5689	PAR-CLIP	20371350
MIRT308818	hsa-miR-3609	PAR-CLIP	22100165
MIRT308819	hsa-miR-548ah-5p	PAR-CLIP	22100165
MIRT448648	hsa-miR-106a-5p	PAR-CLIP	22100165
MIRT448647	hsa-miR-106b-5p	PAR-CLIP	22100165
MIRT448646	hsa-miR-17-5p	PAR-CLIP	22100165
MIRT448645	hsa-miR-20a-5p	PAR-CLIP	22100165
MIRT448644	hsa-miR-20b-5p	PAR-CLIP	22100165
MIRT448643	hsa-miR-519d-3p	PAR-CLIP	22100165
MIRT448642	hsa-miR-526b-3p	PAR-CLIP	22100165
MIRT448641	hsa-miR-93-5p	PAR-CLIP	22100165
MIRT448640	hsa-miR-4796-3p	PAR-CLIP	22100165
MIRT448639	hsa-miR-494-3p	PAR-CLIP	22100165
MIRT448638	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT572622	hsa-miR-3923	PAR-CLIP	20371350
MIRT572621	hsa-miR-4661-3p	PAR-CLIP	20371350
MIRT572620	hsa-miR-1323	PAR-CLIP	20371350
MIRT572619	hsa-miR-548o-3p	PAR-CLIP	20371350
MIRT572618	hsa-miR-325	PAR-CLIP	20371350
MIRT572617	hsa-miR-5689	PAR-CLIP	20371350
MIRT308818	hsa-miR-3609	PAR-CLIP	22100165
MIRT308819	hsa-miR-548ah-5p	PAR-CLIP	22100165
MIRT448648	hsa-miR-106a-5p	PAR-CLIP	22100165
MIRT448647	hsa-miR-106b-5p	PAR-CLIP	22100165
MIRT448646	hsa-miR-17-5p	PAR-CLIP	22100165
MIRT448645	hsa-miR-20a-5p	PAR-CLIP	22100165
MIRT448644	hsa-miR-20b-5p	PAR-CLIP	22100165
MIRT448643	hsa-miR-519d-3p	PAR-CLIP	22100165
MIRT448642	hsa-miR-526b-3p	PAR-CLIP	22100165
MIRT448641	hsa-miR-93-5p	PAR-CLIP	22100165
MIRT448640	hsa-miR-4796-3p	PAR-CLIP	22100165
MIRT448639	hsa-miR-494-3p	PAR-CLIP	22100165
MIRT448638	hsa-miR-510-3p	PAR-CLIP	22100165
MIRT1191071	hsa-miR-101	CLIP-seq
MIRT1191072	hsa-miR-106a	CLIP-seq
MIRT1191073	hsa-miR-106b	CLIP-seq
MIRT1191074	hsa-miR-1207-5p	CLIP-seq
MIRT1191075	hsa-miR-1243	CLIP-seq
MIRT1191076	hsa-miR-1255a	CLIP-seq
MIRT1191077	hsa-miR-1255b	CLIP-seq
MIRT1191078	hsa-miR-1257	CLIP-seq
MIRT1191079	hsa-miR-1261	CLIP-seq
MIRT1191080	hsa-miR-1273g	CLIP-seq
MIRT1191081	hsa-miR-129-5p	CLIP-seq
MIRT1191082	hsa-miR-130a	CLIP-seq
MIRT1191083	hsa-miR-130b	CLIP-seq
MIRT1191084	hsa-miR-132	CLIP-seq
MIRT1191085	hsa-miR-142-5p	CLIP-seq
MIRT1191086	hsa-miR-144	CLIP-seq
MIRT1191087	hsa-miR-17	CLIP-seq
MIRT1191088	hsa-miR-185	CLIP-seq
MIRT1191089	hsa-miR-190	CLIP-seq
MIRT1191090	hsa-miR-190b	CLIP-seq
MIRT1191091	hsa-miR-1972	CLIP-seq
MIRT1191092	hsa-miR-200b	CLIP-seq
MIRT1191093	hsa-miR-200c	CLIP-seq
MIRT1191094	hsa-miR-20a	CLIP-seq
MIRT1191095	hsa-miR-20b	CLIP-seq
MIRT1191096	hsa-miR-212	CLIP-seq
MIRT1191097	hsa-miR-22	CLIP-seq
MIRT1191098	hsa-miR-301a	CLIP-seq
MIRT1191099	hsa-miR-301b	CLIP-seq
MIRT1191100	hsa-miR-3123	CLIP-seq
MIRT1191101	hsa-miR-3145-3p	CLIP-seq
MIRT1191102	hsa-miR-3151	CLIP-seq
MIRT1191103	hsa-miR-3159	CLIP-seq
MIRT1191104	hsa-miR-3200-3p	CLIP-seq
MIRT1191105	hsa-miR-320a	CLIP-seq
MIRT1191106	hsa-miR-320b	CLIP-seq
MIRT1191107	hsa-miR-320c	CLIP-seq
MIRT1191108	hsa-miR-320d	CLIP-seq
MIRT1191109	hsa-miR-329	CLIP-seq
MIRT1191110	hsa-miR-340	CLIP-seq
MIRT1191111	hsa-miR-346	CLIP-seq
MIRT1191112	hsa-miR-34a	CLIP-seq
MIRT1191113	hsa-miR-34c-5p	CLIP-seq
MIRT1191114	hsa-miR-3591-5p	CLIP-seq
MIRT1191115	hsa-miR-3613-3p	CLIP-seq
MIRT1191116	hsa-miR-362-3p	CLIP-seq
MIRT1191117	hsa-miR-3646	CLIP-seq
MIRT1191118	hsa-miR-3647-3p	CLIP-seq
MIRT1191119	hsa-miR-3666	CLIP-seq
MIRT1191120	hsa-miR-3670	CLIP-seq
MIRT1191121	hsa-miR-374c	CLIP-seq
MIRT1191122	hsa-miR-377	CLIP-seq
MIRT1191123	hsa-miR-3941	CLIP-seq
MIRT1191124	hsa-miR-4276	CLIP-seq
MIRT1191125	hsa-miR-429	CLIP-seq
MIRT1191126	hsa-miR-4295	CLIP-seq
MIRT1191127	hsa-miR-4306	CLIP-seq
MIRT1191128	hsa-miR-4310	CLIP-seq
MIRT1191129	hsa-miR-4328	CLIP-seq
MIRT1191130	hsa-miR-4429	CLIP-seq
MIRT1191131	hsa-miR-4447	CLIP-seq
MIRT1191132	hsa-miR-4457	CLIP-seq
MIRT1191133	hsa-miR-4472	CLIP-seq
MIRT1191134	hsa-miR-4473	CLIP-seq
MIRT1191135	hsa-miR-4475	CLIP-seq
MIRT1191136	hsa-miR-449a	CLIP-seq
MIRT1191137	hsa-miR-449b	CLIP-seq
MIRT1191138	hsa-miR-4527	CLIP-seq
MIRT1191139	hsa-miR-454	CLIP-seq
MIRT1191140	hsa-miR-4637	CLIP-seq
MIRT1191141	hsa-miR-4642	CLIP-seq
MIRT1191142	hsa-miR-4644	CLIP-seq
MIRT1191143	hsa-miR-4650-5p	CLIP-seq
MIRT1191144	hsa-miR-4659a-5p	CLIP-seq
MIRT1191145	hsa-miR-4659b-5p	CLIP-seq
MIRT1191146	hsa-miR-466	CLIP-seq
MIRT1191147	hsa-miR-4671-3p	CLIP-seq
MIRT1191148	hsa-miR-4672	CLIP-seq
MIRT1191149	hsa-miR-4699-3p	CLIP-seq
MIRT1191150	hsa-miR-4709-3p	CLIP-seq
MIRT1191151	hsa-miR-4724-3p	CLIP-seq
MIRT1191152	hsa-miR-4763-3p	CLIP-seq
MIRT1191153	hsa-miR-4766-5p	CLIP-seq
MIRT1191154	hsa-miR-4776-3p	CLIP-seq
MIRT1191155	hsa-miR-4778-3p	CLIP-seq
MIRT1191156	hsa-miR-4789-3p	CLIP-seq
MIRT1191157	hsa-miR-4789-5p	CLIP-seq
MIRT1191158	hsa-miR-4790-3p	CLIP-seq
MIRT1191159	hsa-miR-486-3p	CLIP-seq
MIRT1191160	hsa-miR-488	CLIP-seq
MIRT1191161	hsa-miR-490-5p	CLIP-seq
MIRT1191162	hsa-miR-491-5p	CLIP-seq
MIRT1191163	hsa-miR-494	CLIP-seq
MIRT1191164	hsa-miR-499-3p	CLIP-seq
MIRT1191165	hsa-miR-499a-3p	CLIP-seq
MIRT1191166	hsa-miR-501-3p	CLIP-seq
MIRT1191167	hsa-miR-502-3p	CLIP-seq
MIRT1191168	hsa-miR-513b	CLIP-seq
MIRT1191169	hsa-miR-513c	CLIP-seq
MIRT1191170	hsa-miR-514b-5p	CLIP-seq
MIRT1191171	hsa-miR-519d	CLIP-seq
MIRT1191172	hsa-miR-520d-5p	CLIP-seq
MIRT1191173	hsa-miR-524-5p	CLIP-seq
MIRT1191174	hsa-miR-548ah	CLIP-seq
MIRT1191175	hsa-miR-548n	CLIP-seq
MIRT1191176	hsa-miR-548t	CLIP-seq
MIRT1191177	hsa-miR-603	CLIP-seq
MIRT1191178	hsa-miR-655	CLIP-seq
MIRT1191179	hsa-miR-759	CLIP-seq
MIRT1191180	hsa-miR-891b	CLIP-seq
MIRT1191181	hsa-miR-93	CLIP-seq
MIRT1191182	hsa-miR-938	CLIP-seq
MIRT1191183	hsa-miR-214	CLIP-seq
MIRT1191184	hsa-miR-221	CLIP-seq
MIRT1191185	hsa-miR-222	CLIP-seq
MIRT1191100	hsa-miR-3123	CLIP-seq
MIRT1191186	hsa-miR-3619-5p	CLIP-seq
MIRT1191118	hsa-miR-3647-3p	CLIP-seq
MIRT1191187	hsa-miR-3680	CLIP-seq
MIRT1191122	hsa-miR-377	CLIP-seq
MIRT1191123	hsa-miR-3941	CLIP-seq
MIRT1191188	hsa-miR-4291	CLIP-seq
MIRT1191189	hsa-miR-4495	CLIP-seq
MIRT1191190	hsa-miR-4639-3p	CLIP-seq
MIRT1191146	hsa-miR-466	CLIP-seq
MIRT1191148	hsa-miR-4672	CLIP-seq
MIRT1191191	hsa-miR-4731-3p	CLIP-seq
MIRT1191192	hsa-miR-4801	CLIP-seq
MIRT1191166	hsa-miR-501-3p	CLIP-seq
MIRT1191167	hsa-miR-502-3p	CLIP-seq
MIRT1191193	hsa-miR-548a-3p	CLIP-seq
MIRT1191194	hsa-miR-548ac	CLIP-seq
MIRT1191195	hsa-miR-548ae	CLIP-seq
MIRT1191196	hsa-miR-548aj	CLIP-seq
MIRT1191197	hsa-miR-548am	CLIP-seq
MIRT1191198	hsa-miR-548d-3p	CLIP-seq
MIRT1191199	hsa-miR-548e	CLIP-seq
MIRT1191200	hsa-miR-548f	CLIP-seq
MIRT1191201	hsa-miR-548v	CLIP-seq
MIRT1191202	hsa-miR-548x	CLIP-seq
MIRT1191203	hsa-miR-548z	CLIP-seq
MIRT1191204	hsa-miR-761	CLIP-seq
MIRT1191205	hsa-miR-889	CLIP-seq
MIRT1191206	hsa-miR-922	CLIP-seq
MIRT1191072	hsa-miR-106a	CLIP-seq
MIRT1191073	hsa-miR-106b	CLIP-seq
MIRT1191074	hsa-miR-1207-5p	CLIP-seq
MIRT1191207	hsa-miR-1225-5p	CLIP-seq
MIRT1191208	hsa-miR-1252	CLIP-seq
MIRT1191078	hsa-miR-1257	CLIP-seq
MIRT1191081	hsa-miR-129-5p	CLIP-seq
MIRT1191082	hsa-miR-130a	CLIP-seq
MIRT1191083	hsa-miR-130b	CLIP-seq
MIRT1191085	hsa-miR-142-5p	CLIP-seq
MIRT1191087	hsa-miR-17	CLIP-seq
MIRT1191089	hsa-miR-190	CLIP-seq
MIRT1191090	hsa-miR-190b	CLIP-seq
MIRT1191092	hsa-miR-200b	CLIP-seq
MIRT1191093	hsa-miR-200c	CLIP-seq
MIRT1191094	hsa-miR-20a	CLIP-seq
MIRT1191095	hsa-miR-20b	CLIP-seq
MIRT1191097	hsa-miR-22	CLIP-seq
MIRT1191098	hsa-miR-301a	CLIP-seq
MIRT1191099	hsa-miR-301b	CLIP-seq
MIRT1191209	hsa-miR-3121-3p	CLIP-seq
MIRT1191102	hsa-miR-3151	CLIP-seq
MIRT1191103	hsa-miR-3159	CLIP-seq
MIRT1191210	hsa-miR-3189-3p	CLIP-seq
MIRT1191109	hsa-miR-329	CLIP-seq
MIRT1191110	hsa-miR-340	CLIP-seq
MIRT1191111	hsa-miR-346	CLIP-seq
MIRT1191112	hsa-miR-34a	CLIP-seq
MIRT1191113	hsa-miR-34c-5p	CLIP-seq
MIRT1191114	hsa-miR-3591-5p	CLIP-seq
MIRT1191116	hsa-miR-362-3p	CLIP-seq
MIRT1191119	hsa-miR-3666	CLIP-seq
MIRT1191121	hsa-miR-374c	CLIP-seq
MIRT1191123	hsa-miR-3941	CLIP-seq
MIRT1191125	hsa-miR-429	CLIP-seq
MIRT1191126	hsa-miR-4295	CLIP-seq
MIRT1191129	hsa-miR-4328	CLIP-seq
MIRT1191131	hsa-miR-4447	CLIP-seq
MIRT1191132	hsa-miR-4457	CLIP-seq
MIRT1191133	hsa-miR-4472	CLIP-seq
MIRT1191134	hsa-miR-4473	CLIP-seq
MIRT1191136	hsa-miR-449a	CLIP-seq
MIRT1191137	hsa-miR-449b	CLIP-seq
MIRT1191211	hsa-miR-4502	CLIP-seq
MIRT1191138	hsa-miR-4527	CLIP-seq
MIRT1191139	hsa-miR-454	CLIP-seq
MIRT1191141	hsa-miR-4642	CLIP-seq
MIRT1191144	hsa-miR-4659a-5p	CLIP-seq
MIRT1191145	hsa-miR-4659b-5p	CLIP-seq
MIRT1191146	hsa-miR-466	CLIP-seq
MIRT1191147	hsa-miR-4671-3p	CLIP-seq
MIRT1191148	hsa-miR-4672	CLIP-seq
MIRT1191212	hsa-miR-4738-3p	CLIP-seq
MIRT1191152	hsa-miR-4763-3p	CLIP-seq
MIRT1191154	hsa-miR-4776-3p	CLIP-seq
MIRT1191158	hsa-miR-4790-3p	CLIP-seq
MIRT1191159	hsa-miR-486-3p	CLIP-seq
MIRT1191213	hsa-miR-487a	CLIP-seq
MIRT1191162	hsa-miR-491-5p	CLIP-seq
MIRT1191214	hsa-miR-502-5p	CLIP-seq
MIRT1191168	hsa-miR-513b	CLIP-seq
MIRT1191171	hsa-miR-519d	CLIP-seq
MIRT1191174	hsa-miR-548ah	CLIP-seq
MIRT1191177	hsa-miR-603	CLIP-seq
MIRT1191178	hsa-miR-655	CLIP-seq
MIRT1191181	hsa-miR-93	CLIP-seq
MIRT1191182	hsa-miR-938	CLIP-seq
MIRT1922888	hsa-miR-766	CLIP-seq
MIRT1191082	hsa-miR-130a	CLIP-seq
MIRT1191083	hsa-miR-130b	CLIP-seq
MIRT1191098	hsa-miR-301a	CLIP-seq
MIRT1191099	hsa-miR-301b	CLIP-seq
MIRT1191119	hsa-miR-3666	CLIP-seq
MIRT1191126	hsa-miR-4295	CLIP-seq
MIRT1191139	hsa-miR-454	CLIP-seq
MIRT1191147	hsa-miR-4671-3p	CLIP-seq
MIRT1191082	hsa-miR-130a	CLIP-seq
MIRT1191083	hsa-miR-130b	CLIP-seq
MIRT2055378	hsa-miR-2392	CLIP-seq
MIRT1191098	hsa-miR-301a	CLIP-seq
MIRT1191099	hsa-miR-301b	CLIP-seq
MIRT1191110	hsa-miR-340	CLIP-seq
MIRT1191119	hsa-miR-3666	CLIP-seq
MIRT2055379	hsa-miR-4268	CLIP-seq
MIRT1191126	hsa-miR-4295	CLIP-seq
MIRT2055380	hsa-miR-4448	CLIP-seq
MIRT1191132	hsa-miR-4457	CLIP-seq
MIRT1191189	hsa-miR-4495	CLIP-seq
MIRT1191139	hsa-miR-454	CLIP-seq
MIRT1191147	hsa-miR-4671-3p	CLIP-seq
MIRT2055381	hsa-miR-4742-3p	CLIP-seq
MIRT2284255	hsa-miR-1206	CLIP-seq
MIRT1191082	hsa-miR-130a	CLIP-seq
MIRT1191083	hsa-miR-130b	CLIP-seq
MIRT1191098	hsa-miR-301a	CLIP-seq
MIRT1191099	hsa-miR-301b	CLIP-seq
MIRT1191112	hsa-miR-34a	CLIP-seq
MIRT1191113	hsa-miR-34c-5p	CLIP-seq
MIRT1191114	hsa-miR-3591-5p	CLIP-seq
MIRT1191119	hsa-miR-3666	CLIP-seq
MIRT1191126	hsa-miR-4295	CLIP-seq
MIRT1191129	hsa-miR-4328	CLIP-seq
MIRT1191134	hsa-miR-4473	CLIP-seq
MIRT1191136	hsa-miR-449a	CLIP-seq
MIRT1191137	hsa-miR-449b	CLIP-seq
MIRT1191139	hsa-miR-454	CLIP-seq
MIRT1191141	hsa-miR-4642	CLIP-seq
MIRT1191147	hsa-miR-4671-3p	CLIP-seq
MIRT1191156	hsa-miR-4789-3p	CLIP-seq
MIRT1191169	hsa-miR-513c	CLIP-seq
MIRT1191170	hsa-miR-514b-5p	CLIP-seq
MIRT1191175	hsa-miR-548n	CLIP-seq
MIRT1191176	hsa-miR-548t	CLIP-seq
MIRT1191179	hsa-miR-759	CLIP-seq
MIRT2455351	hsa-miR-3127-3p	CLIP-seq
MIRT2455352	hsa-miR-3679-3p	CLIP-seq
MIRT2455353	hsa-miR-4282	CLIP-seq
MIRT2455354	hsa-miR-4446-5p	CLIP-seq
MIRT2455355	hsa-miR-4729	CLIP-seq
MIRT2455356	hsa-miR-579	CLIP-seq
MIRT1191208	hsa-miR-1252	CLIP-seq
MIRT2465737	hsa-miR-3545-3p	CLIP-seq
MIRT2465738	hsa-miR-3921	CLIP-seq
MIRT2465739	hsa-miR-4326	CLIP-seq
MIRT2465740	hsa-miR-4539	CLIP-seq
MIRT2465741	hsa-miR-4635	CLIP-seq
MIRT2465742	hsa-miR-4653-5p	CLIP-seq
MIRT1191214	hsa-miR-502-5p	CLIP-seq
MIRT2465743	hsa-miR-892a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001657	Process	Ureteric bud development	IEA
GO:0001657	Process	Ureteric bud development	ISS	15754038
GO:0001658	Process	Branching involved in ureteric bud morphogenesis	IEA
GO:0001658	Process	Branching involved in ureteric bud morphogenesis	ISS	15754038
GO:0005178	Function	Integrin binding	IEA
GO:0005178	Function	Integrin binding	ISS	15754038
GO:0005178	Function	Integrin binding	NAS	11470831
GO:0005201	Function	Extracellular matrix structural constituent	RCA	25037231, 28675934
GO:0005509	Function	Calcium ion binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	ISS	15754038
GO:0005604	Component	Basement membrane	IEA
GO:0007155	Process	Cell adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	ISS	15754038
GO:0007179	Process	Transforming growth factor beta receptor signaling pathway	IEA
GO:0010811	Process	Positive regulation of cell-substrate adhesion	IEA
GO:0010811	Process	Positive regulation of cell-substrate adhesion	ISS	15754038
GO:0016020	Component	Membrane	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0030198	Process	Extracellular matrix organization	IEA
GO:0030198	Process	Extracellular matrix organization	ISS	15754038
GO:0030485	Component	Smooth muscle contractile fiber	IEA
GO:0030511	Process	Positive regulation of transforming growth factor beta receptor signaling pathway	IEA
GO:0031012	Component	Extracellular matrix	HDA	25037231, 28675934
GO:0031012	Component	Extracellular matrix	IEA
GO:0031012	Component	Extracellular matrix	ISS
GO:0033631	Process	Cell-cell adhesion mediated by integrin	IEA
GO:0033631	Process	Cell-cell adhesion mediated by integrin	ISS	15754038
GO:0045184	Process	Establishment of protein localization	IEA
GO:0045669	Process	Positive regulation of osteoblast differentiation	IEA
GO:0045669	Process	Positive regulation of osteoblast differentiation	ISS	15754038
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045987	Process	Positive regulation of smooth muscle contraction	IEA
GO:0051145	Process	Smooth muscle cell differentiation	IEA
GO:0070062	Component	Extracellular exosome	HDA	19199708
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IEA
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	ISS	15754038
GO:0071356	Process	Cellular response to tumor necrosis factor	IEA
GO:0071356	Process	Cellular response to tumor necrosis factor	ISS	15754038
GO:0097195	Process	Pilomotor reflex	IEA

Other IDs

• MIM: 610306
• HGNC: 27405
• e!Ensembl: ENSG00000168743

Protein

• UniProt ID: Q6UXI9
• Protein name: Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like)
• Protein function: Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues,
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07645	EGF_CA	89 → 133	Calcium-binding EGF domain	Domain
  PF07645	EGF_CA	169 → 212	Calcium-binding EGF domain	Domain
  PF07645	EGF_CA	214 → 253	Calcium-binding EGF domain	Domain
  PF00629	MAM	422 → 562	MAM domain, meprin/A5/mu	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels. {ECO:0000269|PubMed:15754038}.
• Sequence:

  MDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPVC
  QPRCKHGECIGPNKCKCHPGYAGKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYM
  LMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLQLAPDGRTCVDVDECATGRASC
  PRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNIRGSYKC
  KCKEGYQGDGLTCVYIPKVMIEPSGPIHVPKGNGTILKGDTGNNNWIPDVGSTWWPPKTP
  YIPPIITNRPTSKPTTRPTPKPTPIPTPPPPPPLPTELRTPLPPTTPERPTTGLTTIAPA
  ASTPPGGITVDNRVQTDPQKPRGDVFIPRQPSNDLFEIFEIERGVSADDEAKDDPGVLVH
  SCNFDHGLCGWIREKDNDLHWEPIRDPAGGQYLTVSAAKAPGGKAARLVLPLGRLMHSGD
  LCLSFRHKVTGLHSGTLQVFVRKHGAHGAALWGRNGGHGWRQTQITLRGADIKSVVFKGE
  KRRGHTGEIGLDDVSLKKGHCSEER

• Sequence length: 565

Pathways

KEGG:

ECM-receptor interaction