ELMOD2 (ELMO domain containing 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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255520 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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ELMO domain containing 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ELMOD2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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9830169G11Rik |
Chromosome
Chromosome number
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4 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4q31.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q8IZ81 | ||||||||||
Protein name | ELMO domain-containing protein 2 | ||||||||||
Protein function | Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. {ECO:0000269|PubMed:17452337, ECO:0000269 | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed i | ||||||||||
Sequence |
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Sequence length | 293 | ||||||||||
Interactions | View interactions |