Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	254173
Gene name Gene Name - the full gene name approved by the HGNC.	Tubulin tyrosine ligase like 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TTLL10
Synonyms (NCBI Gene) Gene synonyms aliases	TTLL5
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p36.33

Show/Hide all(35)

miRTarBase ID	miRNA	Experiments
MIRT1462320	hsa-miR-1202	CLIP-seq
MIRT1462321	hsa-miR-139-3p	CLIP-seq
MIRT1462322	hsa-miR-3121-5p	CLIP-seq
MIRT1462323	hsa-miR-3158-3p	CLIP-seq
MIRT1462324	hsa-miR-3194-5p	CLIP-seq
MIRT1462325	hsa-miR-3972	CLIP-seq
MIRT1462326	hsa-miR-4446-3p	CLIP-seq
MIRT1462327	hsa-miR-4468	CLIP-seq
MIRT1462328	hsa-miR-4512	CLIP-seq
MIRT2139041	hsa-miR-2467-5p	CLIP-seq
MIRT2139042	hsa-miR-2861	CLIP-seq
MIRT2139043	hsa-miR-329	CLIP-seq
MIRT2139044	hsa-miR-339-3p	CLIP-seq
MIRT2139045	hsa-miR-3612	CLIP-seq
MIRT2139046	hsa-miR-362-3p	CLIP-seq
MIRT2139047	hsa-miR-3921	CLIP-seq
MIRT2139048	hsa-miR-4268	CLIP-seq
MIRT2139049	hsa-miR-4303	CLIP-seq
MIRT2139050	hsa-miR-4443	CLIP-seq
MIRT2139051	hsa-miR-4653-5p	CLIP-seq
MIRT2139052	hsa-miR-582-3p	CLIP-seq
MIRT2139053	hsa-miR-650	CLIP-seq
MIRT2359762	hsa-miR-1197	CLIP-seq
MIRT2139043	hsa-miR-329	CLIP-seq
MIRT2139046	hsa-miR-362-3p	CLIP-seq
MIRT2359763	hsa-miR-4436a	CLIP-seq
MIRT2359764	hsa-miR-665	CLIP-seq
MIRT1462323	hsa-miR-3158-3p	CLIP-seq
MIRT2396464	hsa-miR-3616-5p	CLIP-seq
MIRT2396465	hsa-miR-3647-5p	CLIP-seq
MIRT1462326	hsa-miR-4446-3p	CLIP-seq
MIRT2396466	hsa-miR-4675	CLIP-seq
MIRT2396467	hsa-miR-4687-3p	CLIP-seq
MIRT2396468	hsa-miR-4741	CLIP-seq
MIRT2396469	hsa-miR-573	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	18331838, 25416956
GO:0005524	Function	ATP binding	IEA
GO:0005829	Component	Cytosol	TAS
GO:0018094	Process	Protein polyglycylation	IDA	19524510
GO:0018094	Process	Protein polyglycylation	TAS
GO:0018215	Process	Protein phosphopantetheinylation	IEA
GO:0070735	Function	Protein-glycine ligase activity	IDA	19524510

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q6ZVT0

Protein name

Inactive polyglycylase TTLL10 (Tubulin--tyrosine ligase-like protein 10)

Protein function

Inactive polyglycylase.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03133	TTL	211 → 548	Tubulin-tyrosine ligase family	Family

Sequence

MDHSCTRFIHRRGPPTRTRAGFKRGKRPRIQQRPRARVSGTIPASRLHPAPASQPGPCPA
PGHCPVGPAHERPMGSSQEEGLRCQPSQPDHDADGHCGPDLEGAERASATPGPPGLLNSH
RPADSDDTNAAGPSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQ
RIHDSRRDDYTLKWCEVKSRDSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMS
KASKVPGGVQARLEKDAAAPALEDLPWTSPGYLRPQRVLRMEEFFPETYRLDLKHEREAF
FTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARV
VQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIFFGHGYARLTLSLYDPHSSDLGGHLTNQ
FMQKKSPLYMLLKEHTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLA
AKPKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLV
LETFRKSLRGQKMLPLLSQRRFVLLHNGEADPRPHLGGSCSLRRWPPLPTRQAKSSGPPM
PHAPDQPGARRPAPPPLVPQRPRPPGPDLDSAHDGEPQAPGTEQSGTGNRHPAQEPSPGT
AKEEREEPENARP

Sequence length

673

Interactions

View interactions

	Reactome
			Carboxyterminal post-translational modifications of tubulin

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Ovarian cancer	Ovarian cancer	Conditional KD of IL6 in the OCCA xenograft model delays tumor growth		GWAS, CBGDA

TTLL10 (tubulin tyrosine ligase like 10)