Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	254065
Gene name Gene Name - the full gene name approved by the HGNC.	Bromodomain and WD repeat domain containing 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BRWD3
Synonyms (NCBI Gene) Gene synonyms aliases	BRODL, DCAF20, MRX93, XLID93
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xq21.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilitie

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SNP ID	Visualize variation	Clinical significance	Consequence
rs137853272	T>C,G	Pathogenic	Coding sequence variant, downstream transcript variant, missense variant, genic downstream transcript variant
rs138240307	T>C	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, non coding transcript variant, synonymous variant, genic downstream transcript variant
rs730882185	C>A	Pathogenic	Splice donor variant, genic downstream transcript variant
rs730882186	->T	Pathogenic	Non coding transcript variant, 5 prime UTR variant, frameshift variant, coding sequence variant
rs758800773	T>A,C	Pathogenic	Missense variant, coding sequence variant, non coding transcript variant, stop gained, genic downstream transcript variant
rs863224851	A>C	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant, non coding transcript variant
rs878853055	G>A	Likely-pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant, non coding transcript variant
rs1057518202	->TATT	Pathogenic	Frameshift variant, coding sequence variant, 3 prime UTR variant, non coding transcript variant
rs1057518650	G>A	Pathogenic	Stop gained, coding sequence variant, non coding transcript variant, 5 prime UTR variant
rs1569242657	G>A	Likely-pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant, downstream transcript variant
rs1569245569	C>A	Pathogenic	Coding sequence variant, non coding transcript variant, stop gained, genic downstream transcript variant
rs1569290395	C>T	Likely-pathogenic	Coding sequence variant, upstream transcript variant, genic upstream transcript variant, non coding transcript variant, missense variant
rs1602308324	C>-	Pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant, genic downstream transcript variant
rs1602311804	CA>-	Pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant, genic downstream transcript variant
rs1602352162	G>A	Likely-pathogenic	Coding sequence variant, non coding transcript variant, missense variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT043868	hsa-miR-378a-3p	CLASH	23622248
MIRT559168	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT559167	hsa-miR-567	PAR-CLIP	20371350
MIRT494475	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT559165	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT569265	hsa-miR-8068	PAR-CLIP	20371350
MIRT559163	hsa-miR-297	PAR-CLIP	20371350
MIRT569264	hsa-miR-6818-5p	PAR-CLIP	20371350
MIRT569263	hsa-miR-147a	PAR-CLIP	20371350
MIRT379790	hsa-miR-5010-3p	PAR-CLIP	20371350
MIRT559164	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT559168	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT559167	hsa-miR-567	PAR-CLIP	21572407
MIRT559166	hsa-miR-4711-3p	PAR-CLIP	21572407
MIRT559165	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT559163	hsa-miR-297	PAR-CLIP	21572407
MIRT559164	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT538887	hsa-miR-4704-5p	PAR-CLIP	22012620
MIRT538886	hsa-miR-216b-3p	PAR-CLIP	22012620
MIRT538885	hsa-miR-377-3p	PAR-CLIP	22012620
MIRT494487	hsa-miR-19a-3p	PAR-CLIP	23592263
MIRT494486	hsa-miR-19b-3p	PAR-CLIP	23592263
MIRT494485	hsa-miR-22-3p	PAR-CLIP	23592263
MIRT394462	hsa-miR-548at-5p	PAR-CLIP	23592263
MIRT494484	hsa-miR-3159	PAR-CLIP	23592263
MIRT494483	hsa-miR-126-5p	PAR-CLIP	23592263
MIRT494482	hsa-miR-509-3p	PAR-CLIP	23592263
MIRT494481	hsa-miR-548aj-5p	PAR-CLIP	23592263
MIRT494480	hsa-miR-548f-5p	PAR-CLIP	23592263
MIRT494479	hsa-miR-548g-5p	PAR-CLIP	23592263
MIRT494478	hsa-miR-548x-5p	PAR-CLIP	23592263
MIRT494477	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT494476	hsa-miR-6882-3p	PAR-CLIP	23592263
MIRT494475	hsa-miR-223-5p	PAR-CLIP	23592263
MIRT494474	hsa-miR-556-3p	PAR-CLIP	23592263
MIRT494473	hsa-miR-4795-3p	PAR-CLIP	23592263
MIRT494472	hsa-miR-548aw	PAR-CLIP	23592263
MIRT494471	hsa-miR-651-5p	PAR-CLIP	23592263
MIRT736878	hsa-miR-221-3p	Luciferase reporter assay, Western blotting, Microarray, RNA-seq, qRT-PCR, Flow cytometry	32188026
MIRT559168	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT559167	hsa-miR-567	PAR-CLIP	20371350
MIRT494475	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT559165	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT569265	hsa-miR-8068	PAR-CLIP	20371350
MIRT559163	hsa-miR-297	PAR-CLIP	20371350
MIRT569264	hsa-miR-6818-5p	PAR-CLIP	20371350
MIRT569263	hsa-miR-147a	PAR-CLIP	20371350
MIRT379790	hsa-miR-5010-3p	PAR-CLIP	20371350
MIRT559164	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT559168	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT559167	hsa-miR-567	PAR-CLIP	21572407
MIRT559166	hsa-miR-4711-3p	PAR-CLIP	21572407
MIRT559165	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT559163	hsa-miR-297	PAR-CLIP	21572407
MIRT559164	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT538887	hsa-miR-4704-5p	PAR-CLIP	22012620
MIRT538886	hsa-miR-216b-3p	PAR-CLIP	22012620
MIRT538885	hsa-miR-377-3p	PAR-CLIP	22012620
MIRT494487	hsa-miR-19a-3p	PAR-CLIP	23592263
MIRT494486	hsa-miR-19b-3p	PAR-CLIP	23592263
MIRT494485	hsa-miR-22-3p	PAR-CLIP	23592263
MIRT394462	hsa-miR-548at-5p	PAR-CLIP	23592263
MIRT494484	hsa-miR-3159	PAR-CLIP	23592263
MIRT494483	hsa-miR-126-5p	PAR-CLIP	23592263
MIRT494482	hsa-miR-509-3p	PAR-CLIP	23592263
MIRT494481	hsa-miR-548aj-5p	PAR-CLIP	23592263
MIRT494480	hsa-miR-548f-5p	PAR-CLIP	23592263
MIRT494479	hsa-miR-548g-5p	PAR-CLIP	23592263
MIRT494478	hsa-miR-548x-5p	PAR-CLIP	23592263
MIRT494477	hsa-miR-1468-3p	PAR-CLIP	23592263
MIRT494476	hsa-miR-6882-3p	PAR-CLIP	23592263
MIRT494475	hsa-miR-223-5p	PAR-CLIP	23592263
MIRT494474	hsa-miR-556-3p	PAR-CLIP	23592263
MIRT494473	hsa-miR-4795-3p	PAR-CLIP	23592263
MIRT494472	hsa-miR-548aw	PAR-CLIP	23592263
MIRT494471	hsa-miR-651-5p	PAR-CLIP	23592263
MIRT825797	hsa-let-7a	CLIP-seq
MIRT825798	hsa-let-7b	CLIP-seq
MIRT825799	hsa-let-7c	CLIP-seq
MIRT825800	hsa-let-7d	CLIP-seq
MIRT825801	hsa-let-7e	CLIP-seq
MIRT825802	hsa-let-7f	CLIP-seq
MIRT825803	hsa-let-7g	CLIP-seq
MIRT825804	hsa-let-7i	CLIP-seq
MIRT825805	hsa-miR-106a	CLIP-seq
MIRT825806	hsa-miR-106b	CLIP-seq
MIRT825807	hsa-miR-1183	CLIP-seq
MIRT825808	hsa-miR-1184	CLIP-seq
MIRT825809	hsa-miR-1244	CLIP-seq
MIRT825810	hsa-miR-1252	CLIP-seq
MIRT825811	hsa-miR-1278	CLIP-seq
MIRT825812	hsa-miR-128	CLIP-seq
MIRT825813	hsa-miR-1295	CLIP-seq
MIRT825814	hsa-miR-1297	CLIP-seq
MIRT825815	hsa-miR-1321	CLIP-seq
MIRT825816	hsa-miR-1343	CLIP-seq
MIRT825817	hsa-miR-144	CLIP-seq
MIRT825818	hsa-miR-145	CLIP-seq
MIRT825819	hsa-miR-17	CLIP-seq
MIRT825820	hsa-miR-199a-3p	CLIP-seq
MIRT825821	hsa-miR-199b-3p	CLIP-seq
MIRT825822	hsa-miR-19a	CLIP-seq
MIRT825823	hsa-miR-19b	CLIP-seq
MIRT825824	hsa-miR-200b	CLIP-seq
MIRT825825	hsa-miR-200c	CLIP-seq
MIRT825826	hsa-miR-2053	CLIP-seq
MIRT825827	hsa-miR-20a	CLIP-seq
MIRT825828	hsa-miR-20b	CLIP-seq
MIRT825829	hsa-miR-216b	CLIP-seq
MIRT825830	hsa-miR-23a	CLIP-seq
MIRT825831	hsa-miR-23b	CLIP-seq
MIRT825832	hsa-miR-23c	CLIP-seq
MIRT825833	hsa-miR-24	CLIP-seq
MIRT825834	hsa-miR-26a	CLIP-seq
MIRT825835	hsa-miR-26b	CLIP-seq
MIRT825836	hsa-miR-27a	CLIP-seq
MIRT825837	hsa-miR-27b	CLIP-seq
MIRT825838	hsa-miR-298	CLIP-seq
MIRT825839	hsa-miR-299-5p	CLIP-seq
MIRT825840	hsa-miR-29a	CLIP-seq
MIRT825841	hsa-miR-29b	CLIP-seq
MIRT825842	hsa-miR-29c	CLIP-seq
MIRT825843	hsa-miR-3065-5p	CLIP-seq
MIRT825844	hsa-miR-30a	CLIP-seq
MIRT825845	hsa-miR-30b	CLIP-seq
MIRT825846	hsa-miR-30c	CLIP-seq
MIRT825847	hsa-miR-30d	CLIP-seq
MIRT825848	hsa-miR-30e	CLIP-seq
MIRT825849	hsa-miR-3119	CLIP-seq
MIRT825850	hsa-miR-3129-5p	CLIP-seq
MIRT825851	hsa-miR-3163	CLIP-seq
MIRT825852	hsa-miR-3173-3p	CLIP-seq
MIRT825853	hsa-miR-3180-5p	CLIP-seq
MIRT825854	hsa-miR-3182	CLIP-seq
MIRT825855	hsa-miR-320a	CLIP-seq
MIRT825856	hsa-miR-320b	CLIP-seq
MIRT825857	hsa-miR-320c	CLIP-seq
MIRT825858	hsa-miR-320d	CLIP-seq
MIRT825859	hsa-miR-320e	CLIP-seq
MIRT825860	hsa-miR-323-3p	CLIP-seq
MIRT825861	hsa-miR-340	CLIP-seq
MIRT825862	hsa-miR-342-3p	CLIP-seq
MIRT825863	hsa-miR-3545-3p	CLIP-seq
MIRT825864	hsa-miR-3609	CLIP-seq
MIRT825865	hsa-miR-3613-3p	CLIP-seq
MIRT825866	hsa-miR-3617	CLIP-seq
MIRT825867	hsa-miR-3622b-5p	CLIP-seq
MIRT825868	hsa-miR-3658	CLIP-seq
MIRT825869	hsa-miR-3663-5p	CLIP-seq
MIRT825870	hsa-miR-3674	CLIP-seq
MIRT825871	hsa-miR-3675-3p	CLIP-seq
MIRT825872	hsa-miR-3682-5p	CLIP-seq
MIRT825873	hsa-miR-3689a-5p	CLIP-seq
MIRT825874	hsa-miR-3689b	CLIP-seq
MIRT825875	hsa-miR-3689e	CLIP-seq
MIRT825876	hsa-miR-3689f	CLIP-seq
MIRT825877	hsa-miR-374c	CLIP-seq
MIRT825878	hsa-miR-382	CLIP-seq
MIRT825879	hsa-miR-3915	CLIP-seq
MIRT825880	hsa-miR-3928	CLIP-seq
MIRT825881	hsa-miR-3945	CLIP-seq
MIRT825882	hsa-miR-3973	CLIP-seq
MIRT825883	hsa-miR-4253	CLIP-seq
MIRT825884	hsa-miR-4269	CLIP-seq
MIRT825885	hsa-miR-4282	CLIP-seq
MIRT825886	hsa-miR-4284	CLIP-seq
MIRT825887	hsa-miR-429	CLIP-seq
MIRT825888	hsa-miR-4307	CLIP-seq
MIRT825889	hsa-miR-4318	CLIP-seq
MIRT825890	hsa-miR-4328	CLIP-seq
MIRT825891	hsa-miR-4418	CLIP-seq
MIRT825892	hsa-miR-4419a	CLIP-seq
MIRT825893	hsa-miR-4422	CLIP-seq
MIRT825894	hsa-miR-4424	CLIP-seq
MIRT825895	hsa-miR-4427	CLIP-seq
MIRT825896	hsa-miR-4429	CLIP-seq
MIRT825897	hsa-miR-4438	CLIP-seq
MIRT825898	hsa-miR-4458	CLIP-seq
MIRT825899	hsa-miR-4465	CLIP-seq
MIRT825900	hsa-miR-4476	CLIP-seq
MIRT825901	hsa-miR-4500	CLIP-seq
MIRT825902	hsa-miR-4509	CLIP-seq
MIRT825903	hsa-miR-4510	CLIP-seq
MIRT825904	hsa-miR-452	CLIP-seq
MIRT825905	hsa-miR-4533	CLIP-seq
MIRT825906	hsa-miR-4635	CLIP-seq
MIRT825907	hsa-miR-4646-5p	CLIP-seq
MIRT825908	hsa-miR-4659a-3p	CLIP-seq
MIRT825909	hsa-miR-4659b-3p	CLIP-seq
MIRT825910	hsa-miR-4663	CLIP-seq
MIRT825911	hsa-miR-4676-3p	CLIP-seq
MIRT825912	hsa-miR-4676-5p	CLIP-seq
MIRT825913	hsa-miR-4677-3p	CLIP-seq
MIRT825914	hsa-miR-4679	CLIP-seq
MIRT825915	hsa-miR-4680-3p	CLIP-seq
MIRT825916	hsa-miR-4680-5p	CLIP-seq
MIRT825917	hsa-miR-4682	CLIP-seq
MIRT825918	hsa-miR-4687-3p	CLIP-seq
MIRT825919	hsa-miR-4693-5p	CLIP-seq
MIRT825920	hsa-miR-4703-3p	CLIP-seq
MIRT825921	hsa-miR-4710	CLIP-seq
MIRT825922	hsa-miR-4712-5p	CLIP-seq
MIRT825923	hsa-miR-4723-5p	CLIP-seq
MIRT825924	hsa-miR-4724-3p	CLIP-seq
MIRT825925	hsa-miR-4728-3p	CLIP-seq
MIRT825926	hsa-miR-4728-5p	CLIP-seq
MIRT825927	hsa-miR-4739	CLIP-seq
MIRT825928	hsa-miR-4744	CLIP-seq
MIRT825929	hsa-miR-4747-5p	CLIP-seq
MIRT825930	hsa-miR-4756-5p	CLIP-seq
MIRT825931	hsa-miR-4775	CLIP-seq
MIRT825932	hsa-miR-4777-3p	CLIP-seq
MIRT825933	hsa-miR-4777-5p	CLIP-seq
MIRT825934	hsa-miR-4779	CLIP-seq
MIRT825935	hsa-miR-4796-3p	CLIP-seq
MIRT825936	hsa-miR-488	CLIP-seq
MIRT825937	hsa-miR-491-3p	CLIP-seq
MIRT825938	hsa-miR-505	CLIP-seq
MIRT825939	hsa-miR-509-3-5p	CLIP-seq
MIRT825940	hsa-miR-5095	CLIP-seq
MIRT825941	hsa-miR-509-5p	CLIP-seq
MIRT825942	hsa-miR-5096	CLIP-seq
MIRT825943	hsa-miR-513a-3p	CLIP-seq
MIRT825944	hsa-miR-513a-5p	CLIP-seq
MIRT825945	hsa-miR-518d-5p	CLIP-seq
MIRT825946	hsa-miR-519b-5p	CLIP-seq
MIRT825947	hsa-miR-519c-5p	CLIP-seq
MIRT825948	hsa-miR-519d	CLIP-seq
MIRT825949	hsa-miR-520c-5p	CLIP-seq
MIRT825950	hsa-miR-520g	CLIP-seq
MIRT825951	hsa-miR-520h	CLIP-seq
MIRT825952	hsa-miR-526a	CLIP-seq
MIRT825953	hsa-miR-548ah	CLIP-seq
MIRT825954	hsa-miR-564	CLIP-seq
MIRT825955	hsa-miR-569	CLIP-seq
MIRT825956	hsa-miR-575	CLIP-seq
MIRT825957	hsa-miR-577	CLIP-seq
MIRT825958	hsa-miR-584	CLIP-seq
MIRT825959	hsa-miR-590-3p	CLIP-seq
MIRT825960	hsa-miR-600	CLIP-seq
MIRT825961	hsa-miR-610	CLIP-seq
MIRT825962	hsa-miR-630	CLIP-seq
MIRT825963	hsa-miR-641	CLIP-seq
MIRT825964	hsa-miR-655	CLIP-seq
MIRT825965	hsa-miR-656	CLIP-seq
MIRT825966	hsa-miR-767-5p	CLIP-seq
MIRT825967	hsa-miR-770-5p	CLIP-seq
MIRT825968	hsa-miR-875-5p	CLIP-seq
MIRT825969	hsa-miR-885-3p	CLIP-seq
MIRT825970	hsa-miR-892a	CLIP-seq
MIRT825971	hsa-miR-93	CLIP-seq
MIRT825972	hsa-miR-98	CLIP-seq
MIRT1922613	hsa-miR-532-3p	CLIP-seq
MIRT825808	hsa-miR-1184	CLIP-seq
MIRT1944129	hsa-miR-122	CLIP-seq
MIRT1944130	hsa-miR-124	CLIP-seq
MIRT825809	hsa-miR-1244	CLIP-seq
MIRT825813	hsa-miR-1295	CLIP-seq
MIRT825816	hsa-miR-1343	CLIP-seq
MIRT1944131	hsa-miR-181a	CLIP-seq
MIRT1944132	hsa-miR-181b	CLIP-seq
MIRT1944133	hsa-miR-181c	CLIP-seq
MIRT1944134	hsa-miR-181d	CLIP-seq
MIRT1944135	hsa-miR-188-5p	CLIP-seq
MIRT1944136	hsa-miR-192	CLIP-seq
MIRT825826	hsa-miR-2053	CLIP-seq
MIRT1944137	hsa-miR-21	CLIP-seq
MIRT1944138	hsa-miR-215	CLIP-seq
MIRT1944139	hsa-miR-221	CLIP-seq
MIRT1944140	hsa-miR-222	CLIP-seq
MIRT1944141	hsa-miR-2355-5p	CLIP-seq
MIRT825833	hsa-miR-24	CLIP-seq
MIRT825836	hsa-miR-27a	CLIP-seq
MIRT825837	hsa-miR-27b	CLIP-seq
MIRT825840	hsa-miR-29a	CLIP-seq
MIRT825841	hsa-miR-29b	CLIP-seq
MIRT825842	hsa-miR-29c	CLIP-seq
MIRT1944142	hsa-miR-302f	CLIP-seq
MIRT825844	hsa-miR-30a	CLIP-seq
MIRT825845	hsa-miR-30b	CLIP-seq
MIRT825846	hsa-miR-30c	CLIP-seq
MIRT825847	hsa-miR-30d	CLIP-seq
MIRT825848	hsa-miR-30e	CLIP-seq
MIRT1944143	hsa-miR-3135b	CLIP-seq
MIRT1944144	hsa-miR-3156-5p	CLIP-seq
MIRT825855	hsa-miR-320a	CLIP-seq
MIRT825856	hsa-miR-320b	CLIP-seq
MIRT825857	hsa-miR-320c	CLIP-seq
MIRT825858	hsa-miR-320d	CLIP-seq
MIRT825859	hsa-miR-320e	CLIP-seq
MIRT1944145	hsa-miR-329	CLIP-seq
MIRT825867	hsa-miR-3622b-5p	CLIP-seq
MIRT1944146	hsa-miR-362-3p	CLIP-seq
MIRT1944147	hsa-miR-3647-3p	CLIP-seq
MIRT1944148	hsa-miR-3652	CLIP-seq
MIRT1944149	hsa-miR-3653	CLIP-seq
MIRT825868	hsa-miR-3658	CLIP-seq
MIRT1944150	hsa-miR-3662	CLIP-seq
MIRT825870	hsa-miR-3674	CLIP-seq
MIRT1944151	hsa-miR-3688-3p	CLIP-seq
MIRT1944152	hsa-miR-3689d	CLIP-seq
MIRT825882	hsa-miR-3973	CLIP-seq
MIRT1944153	hsa-miR-4262	CLIP-seq
MIRT825886	hsa-miR-4284	CLIP-seq
MIRT825891	hsa-miR-4418	CLIP-seq
MIRT825896	hsa-miR-4429	CLIP-seq
MIRT1944154	hsa-miR-4430	CLIP-seq
MIRT1944155	hsa-miR-4459	CLIP-seq
MIRT1944156	hsa-miR-4468	CLIP-seq
MIRT1944157	hsa-miR-4490	CLIP-seq
MIRT825907	hsa-miR-4646-5p	CLIP-seq
MIRT825908	hsa-miR-4659a-3p	CLIP-seq
MIRT825909	hsa-miR-4659b-3p	CLIP-seq
MIRT1944158	hsa-miR-4666-3p	CLIP-seq
MIRT1944159	hsa-miR-4666-5p	CLIP-seq
MIRT1944160	hsa-miR-4686	CLIP-seq
MIRT1944161	hsa-miR-4694-3p	CLIP-seq
MIRT1944162	hsa-miR-4699-3p	CLIP-seq
MIRT825920	hsa-miR-4703-3p	CLIP-seq
MIRT825926	hsa-miR-4728-5p	CLIP-seq
MIRT1944163	hsa-miR-4729	CLIP-seq
MIRT825931	hsa-miR-4775	CLIP-seq
MIRT825932	hsa-miR-4777-3p	CLIP-seq
MIRT1944164	hsa-miR-506	CLIP-seq
MIRT825939	hsa-miR-509-3-5p	CLIP-seq
MIRT825941	hsa-miR-509-5p	CLIP-seq
MIRT825942	hsa-miR-5096	CLIP-seq
MIRT825944	hsa-miR-513a-5p	CLIP-seq
MIRT1944165	hsa-miR-520d-5p	CLIP-seq
MIRT825950	hsa-miR-520g	CLIP-seq
MIRT825951	hsa-miR-520h	CLIP-seq
MIRT1944166	hsa-miR-522	CLIP-seq
MIRT1944167	hsa-miR-524-5p	CLIP-seq
MIRT1944168	hsa-miR-548l	CLIP-seq
MIRT1944169	hsa-miR-548v	CLIP-seq
MIRT1944170	hsa-miR-561	CLIP-seq
MIRT825954	hsa-miR-564	CLIP-seq
MIRT825955	hsa-miR-569	CLIP-seq
MIRT825959	hsa-miR-590-3p	CLIP-seq
MIRT1944171	hsa-miR-590-5p	CLIP-seq
MIRT1944172	hsa-miR-624	CLIP-seq
MIRT1944173	hsa-miR-628-5p	CLIP-seq
MIRT1944174	hsa-miR-661	CLIP-seq
MIRT1944175	hsa-miR-664	CLIP-seq
MIRT825797	hsa-let-7a	CLIP-seq
MIRT825798	hsa-let-7b	CLIP-seq
MIRT825799	hsa-let-7c	CLIP-seq
MIRT825800	hsa-let-7d	CLIP-seq
MIRT825801	hsa-let-7e	CLIP-seq
MIRT825802	hsa-let-7f	CLIP-seq
MIRT825803	hsa-let-7g	CLIP-seq
MIRT825804	hsa-let-7i	CLIP-seq
MIRT825808	hsa-miR-1184	CLIP-seq
MIRT2182683	hsa-miR-1207-3p	CLIP-seq
MIRT2182684	hsa-miR-1208	CLIP-seq
MIRT1944129	hsa-miR-122	CLIP-seq
MIRT2182685	hsa-miR-1229	CLIP-seq
MIRT825809	hsa-miR-1244	CLIP-seq
MIRT2182686	hsa-miR-1254	CLIP-seq
MIRT825812	hsa-miR-128	CLIP-seq
MIRT825816	hsa-miR-1343	CLIP-seq
MIRT825817	hsa-miR-144	CLIP-seq
MIRT1944131	hsa-miR-181a	CLIP-seq
MIRT1944132	hsa-miR-181b	CLIP-seq
MIRT1944133	hsa-miR-181c	CLIP-seq
MIRT1944134	hsa-miR-181d	CLIP-seq
MIRT1944136	hsa-miR-192	CLIP-seq
MIRT825826	hsa-miR-2053	CLIP-seq
MIRT1944138	hsa-miR-215	CLIP-seq
MIRT2182687	hsa-miR-22	CLIP-seq
MIRT1944141	hsa-miR-2355-5p	CLIP-seq
MIRT825836	hsa-miR-27a	CLIP-seq
MIRT825837	hsa-miR-27b	CLIP-seq
MIRT2182688	hsa-miR-3074-5p	CLIP-seq
MIRT825844	hsa-miR-30a	CLIP-seq
MIRT825845	hsa-miR-30b	CLIP-seq
MIRT825846	hsa-miR-30c	CLIP-seq
MIRT825847	hsa-miR-30d	CLIP-seq
MIRT825848	hsa-miR-30e	CLIP-seq
MIRT2182689	hsa-miR-3116	CLIP-seq
MIRT1944143	hsa-miR-3135b	CLIP-seq
MIRT2182690	hsa-miR-3154	CLIP-seq
MIRT2182691	hsa-miR-3176	CLIP-seq
MIRT2182692	hsa-miR-338-5p	CLIP-seq
MIRT2182693	hsa-miR-3607-3p	CLIP-seq
MIRT825867	hsa-miR-3622b-5p	CLIP-seq
MIRT1944148	hsa-miR-3652	CLIP-seq
MIRT1944150	hsa-miR-3662	CLIP-seq
MIRT825870	hsa-miR-3674	CLIP-seq
MIRT2182694	hsa-miR-3692	CLIP-seq
MIRT2182695	hsa-miR-3922-3p	CLIP-seq
MIRT2182696	hsa-miR-3935	CLIP-seq
MIRT2182697	hsa-miR-3938	CLIP-seq
MIRT1944153	hsa-miR-4262	CLIP-seq
MIRT2182698	hsa-miR-4277	CLIP-seq
MIRT2182699	hsa-miR-4293	CLIP-seq
MIRT825891	hsa-miR-4418	CLIP-seq
MIRT825893	hsa-miR-4422	CLIP-seq
MIRT1944154	hsa-miR-4430	CLIP-seq
MIRT2182700	hsa-miR-4452	CLIP-seq
MIRT825898	hsa-miR-4458	CLIP-seq
MIRT2182701	hsa-miR-4464	CLIP-seq
MIRT1944157	hsa-miR-4490	CLIP-seq
MIRT2182702	hsa-miR-4493	CLIP-seq
MIRT825901	hsa-miR-4500	CLIP-seq
MIRT2182703	hsa-miR-4512	CLIP-seq
MIRT825908	hsa-miR-4659a-3p	CLIP-seq
MIRT825909	hsa-miR-4659b-3p	CLIP-seq
MIRT1944159	hsa-miR-4666-5p	CLIP-seq
MIRT2182704	hsa-miR-4698	CLIP-seq
MIRT825920	hsa-miR-4703-3p	CLIP-seq
MIRT2182705	hsa-miR-4738-3p	CLIP-seq
MIRT2182706	hsa-miR-4748	CLIP-seq
MIRT2182707	hsa-miR-4753-5p	CLIP-seq
MIRT2182708	hsa-miR-4768-5p	CLIP-seq
MIRT2182709	hsa-miR-4789-5p	CLIP-seq
MIRT825939	hsa-miR-509-3-5p	CLIP-seq
MIRT825941	hsa-miR-509-5p	CLIP-seq
MIRT825942	hsa-miR-5096	CLIP-seq
MIRT825944	hsa-miR-513a-5p	CLIP-seq
MIRT2182710	hsa-miR-548c-3p	CLIP-seq
MIRT2182711	hsa-miR-548g	CLIP-seq
MIRT2182712	hsa-miR-548n	CLIP-seq
MIRT2182713	hsa-miR-548t	CLIP-seq
MIRT2182714	hsa-miR-550a	CLIP-seq
MIRT825959	hsa-miR-590-3p	CLIP-seq
MIRT825960	hsa-miR-600	CLIP-seq
MIRT2182715	hsa-miR-633	CLIP-seq
MIRT2182716	hsa-miR-651	CLIP-seq
MIRT1944174	hsa-miR-661	CLIP-seq
MIRT1944175	hsa-miR-664	CLIP-seq
MIRT2182717	hsa-miR-670	CLIP-seq
MIRT2182718	hsa-miR-764	CLIP-seq
MIRT825966	hsa-miR-767-5p	CLIP-seq
MIRT2182719	hsa-miR-936	CLIP-seq
MIRT825972	hsa-miR-98	CLIP-seq
MIRT1944129	hsa-miR-122	CLIP-seq
MIRT1944130	hsa-miR-124	CLIP-seq
MIRT1944141	hsa-miR-2355-5p	CLIP-seq
MIRT1944143	hsa-miR-3135b	CLIP-seq
MIRT1944144	hsa-miR-3156-5p	CLIP-seq
MIRT1944145	hsa-miR-329	CLIP-seq
MIRT825867	hsa-miR-3622b-5p	CLIP-seq
MIRT1944146	hsa-miR-362-3p	CLIP-seq
MIRT1944148	hsa-miR-3652	CLIP-seq
MIRT1944154	hsa-miR-4430	CLIP-seq
MIRT1944157	hsa-miR-4490	CLIP-seq
MIRT825920	hsa-miR-4703-3p	CLIP-seq
MIRT1944164	hsa-miR-506	CLIP-seq
MIRT1944170	hsa-miR-561	CLIP-seq
MIRT2426669	hsa-miR-3941	CLIP-seq
MIRT2426670	hsa-miR-466	CLIP-seq
MIRT2426671	hsa-miR-4672	CLIP-seq
MIRT2426672	hsa-miR-548p	CLIP-seq
MIRT825814	hsa-miR-1297	CLIP-seq
MIRT2435818	hsa-miR-142-5p	CLIP-seq
MIRT825834	hsa-miR-26a	CLIP-seq
MIRT825835	hsa-miR-26b	CLIP-seq
MIRT1944144	hsa-miR-3156-5p	CLIP-seq
MIRT1944145	hsa-miR-329	CLIP-seq
MIRT1944146	hsa-miR-362-3p	CLIP-seq
MIRT825899	hsa-miR-4465	CLIP-seq
MIRT825932	hsa-miR-4777-3p	CLIP-seq
MIRT1944170	hsa-miR-561	CLIP-seq
MIRT825962	hsa-miR-630	CLIP-seq
MIRT825968	hsa-miR-875-5p	CLIP-seq
MIRT2444906	hsa-miR-105	CLIP-seq
MIRT825807	hsa-miR-1183	CLIP-seq
MIRT2444907	hsa-miR-4766-3p	CLIP-seq
MIRT2182710	hsa-miR-548c-3p	CLIP-seq
MIRT2426672	hsa-miR-548p	CLIP-seq
MIRT2444906	hsa-miR-105	CLIP-seq
MIRT825808	hsa-miR-1184	CLIP-seq
MIRT1944129	hsa-miR-122	CLIP-seq
MIRT2486299	hsa-miR-1246	CLIP-seq
MIRT1944136	hsa-miR-192	CLIP-seq
MIRT1944138	hsa-miR-215	CLIP-seq
MIRT1944141	hsa-miR-2355-5p	CLIP-seq
MIRT2486300	hsa-miR-3122	CLIP-seq
MIRT1944143	hsa-miR-3135b	CLIP-seq
MIRT825867	hsa-miR-3622b-5p	CLIP-seq
MIRT1944148	hsa-miR-3652	CLIP-seq
MIRT1944150	hsa-miR-3662	CLIP-seq
MIRT2486301	hsa-miR-3689a-3p	CLIP-seq
MIRT2486302	hsa-miR-3689c	CLIP-seq
MIRT2486303	hsa-miR-3913-5p	CLIP-seq
MIRT825891	hsa-miR-4418	CLIP-seq
MIRT1944154	hsa-miR-4430	CLIP-seq
MIRT825900	hsa-miR-4476	CLIP-seq
MIRT825926	hsa-miR-4728-5p	CLIP-seq
MIRT2444907	hsa-miR-4766-3p	CLIP-seq
MIRT825939	hsa-miR-509-3-5p	CLIP-seq
MIRT825941	hsa-miR-509-5p	CLIP-seq
MIRT2182710	hsa-miR-548c-3p	CLIP-seq
MIRT2426672	hsa-miR-548p	CLIP-seq
MIRT2486304	hsa-miR-587	CLIP-seq
MIRT2444906	hsa-miR-105	CLIP-seq
MIRT825808	hsa-miR-1184	CLIP-seq
MIRT1944129	hsa-miR-122	CLIP-seq
MIRT2486299	hsa-miR-1246	CLIP-seq
MIRT1944136	hsa-miR-192	CLIP-seq
MIRT1944138	hsa-miR-215	CLIP-seq
MIRT1944141	hsa-miR-2355-5p	CLIP-seq
MIRT1944143	hsa-miR-3135b	CLIP-seq
MIRT825867	hsa-miR-3622b-5p	CLIP-seq
MIRT1944148	hsa-miR-3652	CLIP-seq
MIRT1944150	hsa-miR-3662	CLIP-seq
MIRT825891	hsa-miR-4418	CLIP-seq
MIRT1944154	hsa-miR-4430	CLIP-seq
MIRT2444907	hsa-miR-4766-3p	CLIP-seq
MIRT825939	hsa-miR-509-3-5p	CLIP-seq
MIRT825941	hsa-miR-509-5p	CLIP-seq
MIRT2182710	hsa-miR-548c-3p	CLIP-seq
MIRT2426672	hsa-miR-548p	CLIP-seq
MIRT2486304	hsa-miR-587	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007010	Process	Cytoskeleton organization	IBA
GO:0007010	Process	Cytoskeleton organization	IMP	21834987
GO:0008360	Process	Regulation of cell shape	IBA
GO:0008360	Process	Regulation of cell shape	IEA
GO:0008360	Process	Regulation of cell shape	IMP	21834987

MIM	HGNC	e!Ensembl
300553	17342	ENSG00000165288

Protein

UniProt ID

Q6RI45

Protein name

Bromodomain and WD repeat-containing protein 3

Protein function

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00400	WD40	169 → 207	WD domain, G-beta repeat	Repeat
PF00400	WD40	212 → 250	WD domain, G-beta repeat	Repeat
PF00400	WD40	254 → 296	WD domain, G-beta repeat	Repeat
PF00400	WD40	352 → 392	WD domain, G-beta repeat	Repeat
PF00400	WD40	455 → 494	WD domain, G-beta repeat	Repeat
PF00439	Bromodomain	1147 → 1233	Bromodomain	Domain
PF00439	Bromodomain	1309 → 1418	Bromodomain	Domain

Tissue specificity

TISSUE SPECIFICITY: Found in most adult tissues. Down-regulated in a majority of the B-CLL cases examined. {ECO:0000269|PubMed:15543602}.

Sequence

MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDL
VAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGS
AFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHL
SSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAG
SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK
TMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELES
HTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDK
ITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRI
ILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF
GFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTK
FQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGIIRELQREQDL
RLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRSQM
ATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEP
SCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQNSGVQEDSDSSSEEDETVGTSDASVEDP
VVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRKICSSSDEENLKSLEERQKK
PKQTRKKKGGLVSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAV
RKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESF
SIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDS
SFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGA
HSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFY
RRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAE
ERNSTDAEEDTEIVDLDSDGPGTSSGRKVKCRGRRQSLKCNPDAWKKQCKELLSLIYERE
DSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLE
AGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQS
QKRRRPRYRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVS
DAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLPVKQDHSLDGPLT
NGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCG
SDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWG
RWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFDTMFSGR
FSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGW
NY

Sequence length

1802

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Mental retardation	intellectual disability	rs1602308324	N/A
Mental Retardation, X-Linked	Intellectual disability, X-linked 93	rs137853272, rs878853055, rs1057518650, rs1602311804, rs1569290395, rs730882185, rs730882186	N/A

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
developmental delay	Developmental delay	N/A	N/A	ClinVar
Epilepsy	self-limited epilepsy with centrotemporal spikes	N/A	N/A	GenCC
Infantile Spasms	infantile spasms	N/A	N/A	GenCC

Show/Hide Text Mining Associations (22)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	39190898
Azoospermia Nonobstructive	Associate	36017582
Breast Neoplasms	Stimulate	22024541
Breast Neoplasms	Associate	33617509
Developmental Disabilities	Associate	24372385
Ear Diseases	Associate	17668385
Epilepsies Partial	Associate	36514184
Epilepsy	Associate	24372385, 36514184
Epilepsy Rolandic	Associate	24372385
Epilepsy rolandic with paroxysmal exercise induced dystonia and writer's cramp	Associate	24372385
Growth Disorders	Associate	26323392
Hepatitis D	Associate	35687490
Immune System Diseases	Associate	35687490
Intellectual Disability	Associate	17668385, 26323392, 36514184
Lymphoma	Associate	35687490
Lymphoma B Cell	Associate	29166413
Lymphoma Large B Cell Diffuse	Associate	35687490
Megalencephaly	Associate	17668385
Mental Retardation X Linked	Associate	17668385
Multiple Myeloma	Associate	29166413
Neoplasms	Associate	35687490
Seizures	Associate	36514184

BRWD3 (bromodomain and WD repeat domain containing 3)