Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
253559
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Cell adhesion molecule 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
CADM2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
IGSF4D, NECL3, Necl-3, SynCAM 2, SynCAM-2, synCAM2 |
Chromosome
Chromosome number
|
3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
3p12.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Glaucoma |
Glaucoma, Glaucoma, Open-Angle |
rs121918355, rs1566660365, rs1566635134, rs121918356, rs1566634475, rs28936700, rs55771538, rs28936701, rs104893622, rs55989760, rs72549387, rs104893628, rs2125316417, rs104893629, rs74315328, rs121909193, rs74315330, rs74315329, rs74315332, rs74315334, rs74315336, rs74315338, rs74315341, rs121909194, rs74315331, rs1558603396, rs387907175, rs587778873, rs587778875, rs104894979, rs137854895, rs766425037, rs72549380, rs148542782, rs541217363, rs753021890, rs771076928, rs56010818, rs777678299, rs1446110883, rs1573274915, rs1587545234, rs751768343, rs944452644 View all (29 more) |
30104761, 30054594, 29891935 |
Leukemia |
Leukemia, Myelocytic, Acute |
rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 |
27903959 |
Obesity |
Obesity |
rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs193922650, rs193922685, rs193922687, rs751160202, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829 View all (27 more) |
23563607 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
31374203 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Neuroticism |
Neuroticism |
|
|
GWAS |
Bipolar Disorder |
Bipolar Disorder |
|
|
GWAS |
Metabolic Syndrome |
Metabolic Syndrome |
|
|
GWAS |
Gout |
Gout |
|
|
GWAS |
Breast Cancer |
Breast Cancer |
Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients |
|
GWAS, CBGDA |
Irritable Bowel Syndrome |
Irritable Bowel Syndrome |
|
|
GWAS |
Dyslexia |
Dyslexia |
|
|
GWAS |
Insomnia |
Insomnia |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Alzheimer Disease |
Associate
|
27046643, 29899525 |
Anxiety Disorders |
Associate
|
34741163 |
Attention Deficit Disorder with Hyperactivity |
Associate
|
36774336, 38335780 |
Autism Spectrum Disorder |
Associate
|
21996756 |
Autistic Disorder |
Associate
|
28973307, 36150388 |
Bipolar Disorder |
Associate
|
33168801 |
Carcinogenesis |
Associate
|
37228062 |
Carcinoma Hepatocellular |
Inhibit
|
29506532 |
Carcinoma Hepatocellular |
Associate
|
37228062, 38126999 |
Carcinoma Renal Cell |
Associate
|
34222474 |
Colorectal Neoplasms |
Associate
|
36576985 |
Disruptive Impulse Control and Conduct Disorders |
Associate
|
30718321 |
Frontotemporal Dementia |
Associate
|
35509074 |
Irritable Bowel Syndrome |
Associate
|
34741163 |
Liver Cirrhosis |
Associate
|
37228062 |
Memory Disorders |
Associate
|
36774336 |
Neoplasm Metastasis |
Associate
|
29506532 |
Neoplasms |
Inhibit
|
21062931, 29506532 |
Neoplasms |
Associate
|
21307934 |
Neurodegenerative Diseases |
Associate
|
27046643 |
Obesity |
Associate
|
23539184, 29899525, 31341224 |
Overweight |
Associate
|
31341224 |
Pancreatic Neoplasms |
Associate
|
31856624 |
Parkinson Disease |
Associate
|
28973307 |
Personality Disorders |
Associate
|
30718321 |
Prostatic Neoplasms |
Inhibit
|
21062931 |
Prostatic Neoplasms |
Associate
|
21307934 |
Prostatitis |
Inhibit
|
21062931 |
Schizophrenia |
Associate
|
27046643, 28973307, 33346031, 35509074 |
Substance Related Disorders |
Associate
|
37796845 |
Weight Loss |
Associate
|
31341224 |
|