ZBTB38 (zinc finger and BTB domain containing 38)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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253461 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Zinc finger and BTB domain containing 38 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ZBTB38 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CIBZ, PPP1R171, ZNF921 |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q23 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with a |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q8NAP3 | |||||||||||||||||||||||||
| Protein name | Zinc finger and BTB domain-containing protein 38 | |||||||||||||||||||||||||
| Protein function | Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a | |||||||||||||||||||||||||
| PDB | 6E93 , 6E94 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1195 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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