Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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253461
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Zinc finger and BTB domain containing 38 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ZBTB38 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CIBZ, PPP1R171, ZNF921 |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q23 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with a |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Breast carcinoma |
Breast Carcinoma |
rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038 View all (71 more) |
29059683 |
Multiple sclerosis |
Multiple Sclerosis |
rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544 View all (4 more) |
24076602 |
Myopia |
Myopia |
rs387907109, rs146936371, rs587776903, rs786205127, rs398122836, rs199624584, rs587777625, rs786205216, rs758872875, rs764211125, rs1135402746, rs765658563, rs1555941129, rs1555941116, rs199923805, rs782555528, rs1554862601, rs1586620121, rs1387950081, rs2051026773, rs1422332023 View all (6 more) |
27182965 |
Prostate cancer |
Malignant neoplasm of prostate, Prostate carcinoma |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
21743467, 29892016 |
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Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Asthma |
Asthma, Childhood asthma |
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30929738 |
ClinVar, GWAS |
Chronic obstructive pulmonary disease |
Chronic Obstructive Airway Disease |
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30804561 |
ClinVar |
Crohn disease |
Crohn Disease |
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28067908 |
ClinVar |
Eczema |
Eczema |
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GWAS |
Multiple Sclerosis |
Multiple Sclerosis |
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GWAS |
Dermatitis |
Dermatitis |
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GWAS |
Diabetes |
Diabetes |
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GWAS |
Hyperopia |
Hyperopia |
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GWAS |
Breast Cancer |
Breast Cancer |
Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients |
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GWAS, CBGDA |
Crohn Disease |
Crohn Disease |
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GWAS |
Dementia |
Dementia |
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GWAS |
Inflammatory Bowel Disease |
Inflammatory Bowel Disease |
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GWAS |
Carpal Tunnel Syndrome |
Carpal Tunnel Syndrome |
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GWAS |
Atrial Fibrillation |
Atrial Fibrillation |
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GWAS |
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