Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	2521
Gene name	FUS RNA binding protein
Gene symbol	FUS
Synonyms (NCBI Gene)	ALS6ETM4FUS1HNRNPP2POMP75TLSaltFUS
Chromosome	16
Chromosome location	16p11.2
Summary	This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the F

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SNP ID	Visualize variation	Clinical significance	Consequence
rs72550890	CGGCGGCGGCGG>-,CGG,CGGCGG,CGGCGGCGG,CGGCGGCGGCGGCGG,CGGCGGCGGCGGCGGCGG,CGGCGGCGGCGGCGGCGGCGG,CGGCGGCGGCGGCGGCGGCGGCGG,CGGCGGCGGCGGCGGCGGCGGCGGCGG,CGGCGGCGGCGGCGGCGGCGGCGGCGGCGG	Benign, uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Non coding transcript variant, inframe insertion, inframe deletion, coding sequence variant
rs121909667	C>G	Pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs121909668	C>A,G,T	Pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs121909669	G>A	Pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs121909671	G>A,T	Pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs186547381	C>T	Uncertain-significance, pathogenic	Non coding transcript variant, missense variant, coding sequence variant
rs190724342	C>T	Conflicting-interpretations-of-pathogenicity	Non coding transcript variant, coding sequence variant, synonymous variant
rs267606831	G>A	Pathogenic	Non coding transcript variant, missense variant, coding sequence variant
rs267606832	C>G,T	Pathogenic	Non coding transcript variant, missense variant, coding sequence variant, synonymous variant
rs267606833	A>T	Pathogenic	Non coding transcript variant, missense variant, coding sequence variant
rs376510148	G>A	Conflicting-interpretations-of-pathogenicity	Non coding transcript variant, 3 prime UTR variant
rs387906627	C>T	Pathogenic	Non coding transcript variant, coding sequence variant, stop gained
rs387906628	G>A	Pathogenic	Non coding transcript variant, synonymous variant, coding sequence variant, missense variant
rs387907274	C>T	Pathogenic	Non coding transcript variant, coding sequence variant, stop gained
rs752076094	A>G	Likely-pathogenic	Missense variant, synonymous variant, non coding transcript variant, coding sequence variant
rs764487847	C>G,T	Likely-pathogenic	Coding sequence variant, 5 prime UTR variant, non coding transcript variant, stop gained, upstream transcript variant, genic upstream transcript variant, missense variant
rs886041389	G>C	Pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs886041390	C>T	Pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs886041577	GA>-	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs886041776	->GGTGG	Pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant
rs1085308015	A>C,G	Likely-pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs1161032867	G>-,GGGG	Pathogenic	Inframe insertion, frameshift variant, non coding transcript variant, coding sequence variant
rs1555509569	A>-	Pathogenic	Splice acceptor variant
rs1555509609	A>C,G,T	Likely-pathogenic	Missense variant, synonymous variant, non coding transcript variant, coding sequence variant
rs1555509693	A>G	Pathogenic, uncertain-significance	Missense variant, non coding transcript variant, coding sequence variant
rs1596908744	TT>-	Pathogenic	Non coding transcript variant, coding sequence variant, stop gained
rs1596912983	->AG	Pathogenic	Non coding transcript variant, coding sequence variant, frameshift variant

619

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004196	hsa-miR-197-3p	Microarray	16822819
MIRT047505	hsa-miR-10a-5p	CLASH	23622248
MIRT047505	hsa-miR-10a-5p	CLASH	23622248
MIRT047277	hsa-miR-181b-5p	CLASH	23622248
MIRT046900	hsa-miR-221-3p	CLASH	23622248
MIRT046086	hsa-miR-125b-5p	CLASH	23622248
MIRT043384	hsa-miR-331-3p	CLASH	23622248
MIRT043384	hsa-miR-331-3p	CLASH	23622248
MIRT040469	hsa-miR-615-3p	CLASH	23622248
MIRT036115	hsa-miR-1296-5p	CLASH	23622248
MIRT035826	hsa-miR-664a-3p	CLASH	23622248
MIRT052707	hsa-miR-1260b	CLASH	23622248
MIRT672490	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT672489	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT672488	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT672487	hsa-miR-4537	HITS-CLIP	23824327
MIRT672486	hsa-miR-4252	HITS-CLIP	23824327
MIRT672485	hsa-miR-1254	HITS-CLIP	23824327
MIRT672484	hsa-miR-3116	HITS-CLIP	23824327
MIRT672483	hsa-miR-6744-5p	HITS-CLIP	23824327
MIRT672482	hsa-miR-1255a	HITS-CLIP	23824327
MIRT672481	hsa-miR-1255b-5p	HITS-CLIP	23824327
MIRT672480	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT672479	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT672478	hsa-miR-7703	HITS-CLIP	23824327
MIRT623879	hsa-miR-3130-5p	HITS-CLIP	23824327
MIRT623878	hsa-miR-4482-5p	HITS-CLIP	23824327
MIRT623876	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT623875	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT623874	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT623873	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT623872	hsa-miR-612	HITS-CLIP	23824327
MIRT623871	hsa-miR-6860	HITS-CLIP	23824327
MIRT650110	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT650109	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT650108	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT650107	hsa-miR-1273e	HITS-CLIP	23824327
MIRT623879	hsa-miR-3130-5p	HITS-CLIP	23824327
MIRT623878	hsa-miR-4482-5p	HITS-CLIP	23824327
MIRT623877	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT623876	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT623875	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT623874	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT623873	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT623872	hsa-miR-612	HITS-CLIP	23824327
MIRT623871	hsa-miR-6860	HITS-CLIP	23824327
MIRT623870	hsa-miR-661	HITS-CLIP	23824327
MIRT623879	hsa-miR-3130-5p	HITS-CLIP	23824327
MIRT623878	hsa-miR-4482-5p	HITS-CLIP	23824327
MIRT623877	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT623876	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT623875	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT623874	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT623873	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT623872	hsa-miR-612	HITS-CLIP	23824327
MIRT623871	hsa-miR-6860	HITS-CLIP	23824327
MIRT623870	hsa-miR-661	HITS-CLIP	23824327
MIRT672485	hsa-miR-1254	PAR-CLIP	27292025
MIRT672485	hsa-miR-1254	PAR-CLIP	27292025
MIRT672482	hsa-miR-1255a	PAR-CLIP	27292025
MIRT672482	hsa-miR-1255a	PAR-CLIP	27292025
MIRT672481	hsa-miR-1255b-5p	PAR-CLIP	27292025
MIRT672481	hsa-miR-1255b-5p	PAR-CLIP	27292025
MIRT672484	hsa-miR-3116	PAR-CLIP	27292025
MIRT672484	hsa-miR-3116	PAR-CLIP	27292025
MIRT672486	hsa-miR-4252	PAR-CLIP	27292025
MIRT672488	hsa-miR-4793-3p	PAR-CLIP	27292025
MIRT672488	hsa-miR-4793-3p	PAR-CLIP	27292025
MIRT672490	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT672490	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT672480	hsa-miR-6512-3p	PAR-CLIP	27292025
MIRT672479	hsa-miR-6720-5p	PAR-CLIP	27292025
MIRT672483	hsa-miR-6744-5p	PAR-CLIP	27292025
MIRT672483	hsa-miR-6744-5p	PAR-CLIP	27292025
MIRT623877	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT672489	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT672478	hsa-miR-7703	PAR-CLIP	27292025
MIRT734661	hsa-miR-133a-5p	Luciferase reporter assay	31736422
MIRT672490	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT672489	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT672488	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT672487	hsa-miR-4537	HITS-CLIP	23824327
MIRT672486	hsa-miR-4252	HITS-CLIP	23824327
MIRT672485	hsa-miR-1254	HITS-CLIP	23824327
MIRT672484	hsa-miR-3116	HITS-CLIP	23824327
MIRT672483	hsa-miR-6744-5p	HITS-CLIP	23824327
MIRT672482	hsa-miR-1255a	HITS-CLIP	23824327
MIRT672481	hsa-miR-1255b-5p	HITS-CLIP	23824327
MIRT672480	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT672479	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT672478	hsa-miR-7703	HITS-CLIP	23824327
MIRT623879	hsa-miR-3130-5p	HITS-CLIP	23824327
MIRT623878	hsa-miR-4482-5p	HITS-CLIP	23824327
MIRT623876	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT623875	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT623874	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT623873	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT623872	hsa-miR-612	HITS-CLIP	23824327
MIRT623871	hsa-miR-6860	HITS-CLIP	23824327
MIRT650110	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT650109	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT650108	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT650107	hsa-miR-1273e	HITS-CLIP	23824327
MIRT623879	hsa-miR-3130-5p	HITS-CLIP	23824327
MIRT623878	hsa-miR-4482-5p	HITS-CLIP	23824327
MIRT623877	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT623876	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT623875	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT623874	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT623873	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT623872	hsa-miR-612	HITS-CLIP	23824327
MIRT623871	hsa-miR-6860	HITS-CLIP	23824327
MIRT623870	hsa-miR-661	HITS-CLIP	23824327
MIRT623879	hsa-miR-3130-5p	HITS-CLIP	23824327
MIRT623878	hsa-miR-4482-5p	HITS-CLIP	23824327
MIRT623877	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT623876	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT623875	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT623874	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT623873	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT623872	hsa-miR-612	HITS-CLIP	23824327
MIRT623871	hsa-miR-6860	HITS-CLIP	23824327
MIRT623870	hsa-miR-661	HITS-CLIP	23824327
MIRT1006297	hsa-miR-1262	CLIP-seq
MIRT1006298	hsa-miR-1292	CLIP-seq
MIRT1006299	hsa-miR-1303	CLIP-seq
MIRT1006300	hsa-miR-202	CLIP-seq
MIRT1006301	hsa-miR-3121-5p	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT1006303	hsa-miR-3125	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT1006305	hsa-miR-3189-3p	CLIP-seq
MIRT1006306	hsa-miR-3202	CLIP-seq
MIRT1006307	hsa-miR-330-3p	CLIP-seq
MIRT1006308	hsa-miR-338-3p	CLIP-seq
MIRT1006309	hsa-miR-3609	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT1006317	hsa-miR-374c	CLIP-seq
MIRT1006318	hsa-miR-376c	CLIP-seq
MIRT1006319	hsa-miR-383	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006321	hsa-miR-3916	CLIP-seq
MIRT1006322	hsa-miR-4257	CLIP-seq
MIRT1006323	hsa-miR-4271	CLIP-seq
MIRT1006324	hsa-miR-4275	CLIP-seq
MIRT1006325	hsa-miR-4471	CLIP-seq
MIRT1006326	hsa-miR-4506	CLIP-seq
MIRT1006327	hsa-miR-452	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006329	hsa-miR-4533	CLIP-seq
MIRT1006330	hsa-miR-4639-3p	CLIP-seq
MIRT1006331	hsa-miR-4676-3p	CLIP-seq
MIRT1006332	hsa-miR-4701-3p	CLIP-seq
MIRT1006333	hsa-miR-4716-3p	CLIP-seq
MIRT1006334	hsa-miR-4725-3p	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT1006337	hsa-miR-4772-5p	CLIP-seq
MIRT1006338	hsa-miR-501-5p	CLIP-seq
MIRT1006339	hsa-miR-544b	CLIP-seq
MIRT1006340	hsa-miR-548ac	CLIP-seq
MIRT1006341	hsa-miR-548ah	CLIP-seq
MIRT1006342	hsa-miR-548c-3p	CLIP-seq
MIRT1006343	hsa-miR-548d-3p	CLIP-seq
MIRT1006344	hsa-miR-548z	CLIP-seq
MIRT1006345	hsa-miR-625	CLIP-seq
MIRT1006346	hsa-miR-655	CLIP-seq
MIRT1006347	hsa-miR-873	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006349	hsa-miR-1207-5p	CLIP-seq
MIRT1006350	hsa-miR-1225-5p	CLIP-seq
MIRT1006351	hsa-miR-1228	CLIP-seq
MIRT1006352	hsa-miR-1252	CLIP-seq
MIRT1006353	hsa-miR-1255b	CLIP-seq
MIRT1006297	hsa-miR-1262	CLIP-seq
MIRT1006354	hsa-miR-1285	CLIP-seq
MIRT1006298	hsa-miR-1292	CLIP-seq
MIRT1006355	hsa-miR-1304	CLIP-seq
MIRT1006356	hsa-miR-139-5p	CLIP-seq
MIRT1006357	hsa-miR-141	CLIP-seq
MIRT1006358	hsa-miR-145	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT1006360	hsa-miR-200a	CLIP-seq
MIRT1006300	hsa-miR-202	CLIP-seq
MIRT1006361	hsa-miR-224	CLIP-seq
MIRT1006362	hsa-miR-2355-5p	CLIP-seq
MIRT1006363	hsa-miR-2467-3p	CLIP-seq
MIRT1006364	hsa-miR-3064-3p	CLIP-seq
MIRT1006365	hsa-miR-3074-5p	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT1006303	hsa-miR-3125	CLIP-seq
MIRT1006366	hsa-miR-3129-3p	CLIP-seq
MIRT1006367	hsa-miR-3136-3p	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT1006368	hsa-miR-3174	CLIP-seq
MIRT1006369	hsa-miR-3177-5p	CLIP-seq
MIRT1006305	hsa-miR-3189-3p	CLIP-seq
MIRT1006306	hsa-miR-3202	CLIP-seq
MIRT1006307	hsa-miR-330-3p	CLIP-seq
MIRT1006370	hsa-miR-342-3p	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006371	hsa-miR-3614-5p	CLIP-seq
MIRT1006372	hsa-miR-3617	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT1006373	hsa-miR-3622b-5p	CLIP-seq
MIRT1006374	hsa-miR-3662	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT1006375	hsa-miR-3672	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006376	hsa-miR-370	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT1006318	hsa-miR-376c	CLIP-seq
MIRT1006319	hsa-miR-383	CLIP-seq
MIRT1006377	hsa-miR-3908	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006321	hsa-miR-3916	CLIP-seq
MIRT1006378	hsa-miR-3927	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT1006380	hsa-miR-3940-5p	CLIP-seq
MIRT1006381	hsa-miR-3945	CLIP-seq
MIRT1006382	hsa-miR-3975	CLIP-seq
MIRT1006383	hsa-miR-4253	CLIP-seq
MIRT1006322	hsa-miR-4257	CLIP-seq
MIRT1006324	hsa-miR-4275	CLIP-seq
MIRT1006384	hsa-miR-4276	CLIP-seq
MIRT1006385	hsa-miR-4278	CLIP-seq
MIRT1006386	hsa-miR-4282	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1006388	hsa-miR-4433	CLIP-seq
MIRT1006389	hsa-miR-4436a	CLIP-seq
MIRT1006390	hsa-miR-4459	CLIP-seq
MIRT1006391	hsa-miR-4463	CLIP-seq
MIRT1006325	hsa-miR-4471	CLIP-seq
MIRT1006392	hsa-miR-4474-5p	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT1006394	hsa-miR-4493	CLIP-seq
MIRT1006326	hsa-miR-4506	CLIP-seq
MIRT1006395	hsa-miR-4507	CLIP-seq
MIRT1006396	hsa-miR-4509	CLIP-seq
MIRT1006397	hsa-miR-4514	CLIP-seq
MIRT1006329	hsa-miR-4533	CLIP-seq
MIRT1006398	hsa-miR-4646-5p	CLIP-seq
MIRT1006399	hsa-miR-4649-3p	CLIP-seq
MIRT1006400	hsa-miR-4666-5p	CLIP-seq
MIRT1006401	hsa-miR-4679	CLIP-seq
MIRT1006402	hsa-miR-4692	CLIP-seq
MIRT1006403	hsa-miR-4693-3p	CLIP-seq
MIRT1006404	hsa-miR-4695-5p	CLIP-seq
MIRT1006405	hsa-miR-4700-3p	CLIP-seq
MIRT1006332	hsa-miR-4701-3p	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006406	hsa-miR-4731-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT1006407	hsa-miR-4747-5p	CLIP-seq
MIRT1006408	hsa-miR-4763-3p	CLIP-seq
MIRT1006409	hsa-miR-4768-3p	CLIP-seq
MIRT1006337	hsa-miR-4772-5p	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT1006411	hsa-miR-520d-5p	CLIP-seq
MIRT1006412	hsa-miR-522	CLIP-seq
MIRT1006413	hsa-miR-524-5p	CLIP-seq
MIRT1006414	hsa-miR-541	CLIP-seq
MIRT1006415	hsa-miR-544	CLIP-seq
MIRT1006339	hsa-miR-544b	CLIP-seq
MIRT1006416	hsa-miR-548aa	CLIP-seq
MIRT1006340	hsa-miR-548ac	CLIP-seq
MIRT1006343	hsa-miR-548d-3p	CLIP-seq
MIRT1006417	hsa-miR-548m	CLIP-seq
MIRT1006418	hsa-miR-548v	CLIP-seq
MIRT1006344	hsa-miR-548z	CLIP-seq
MIRT1006419	hsa-miR-615-5p	CLIP-seq
MIRT1006420	hsa-miR-635	CLIP-seq
MIRT1006421	hsa-miR-641	CLIP-seq
MIRT1006422	hsa-miR-654-5p	CLIP-seq
MIRT1006423	hsa-miR-663b	CLIP-seq
MIRT1006424	hsa-miR-665	CLIP-seq
MIRT1006425	hsa-miR-7	CLIP-seq
MIRT1006426	hsa-miR-766	CLIP-seq
MIRT1006427	hsa-miR-767-3p	CLIP-seq
MIRT1006428	hsa-miR-769-5p	CLIP-seq
MIRT1006347	hsa-miR-873	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006371	hsa-miR-3614-5p	CLIP-seq
MIRT1006350	hsa-miR-1225-5p	CLIP-seq
MIRT1006297	hsa-miR-1262	CLIP-seq
MIRT1006357	hsa-miR-141	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT1006360	hsa-miR-200a	CLIP-seq
MIRT1006300	hsa-miR-202	CLIP-seq
MIRT1998219	hsa-miR-2114	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT1006303	hsa-miR-3125	CLIP-seq
MIRT1006367	hsa-miR-3136-3p	CLIP-seq
MIRT1998220	hsa-miR-3145-5p	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT1006305	hsa-miR-3189-3p	CLIP-seq
MIRT1998221	hsa-miR-3192	CLIP-seq
MIRT1006306	hsa-miR-3202	CLIP-seq
MIRT1998222	hsa-miR-320a	CLIP-seq
MIRT1998223	hsa-miR-320b	CLIP-seq
MIRT1998224	hsa-miR-320c	CLIP-seq
MIRT1998225	hsa-miR-320d	CLIP-seq
MIRT1998226	hsa-miR-326	CLIP-seq
MIRT1998227	hsa-miR-330-5p	CLIP-seq
MIRT1006308	hsa-miR-338-3p	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT1006318	hsa-miR-376c	CLIP-seq
MIRT1006319	hsa-miR-383	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006321	hsa-miR-3916	CLIP-seq
MIRT1998228	hsa-miR-3926	CLIP-seq
MIRT1998229	hsa-miR-3928	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT1006322	hsa-miR-4257	CLIP-seq
MIRT1006323	hsa-miR-4271	CLIP-seq
MIRT1006324	hsa-miR-4275	CLIP-seq
MIRT1006386	hsa-miR-4282	CLIP-seq
MIRT1998230	hsa-miR-4314	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1998231	hsa-miR-4424	CLIP-seq
MIRT1998232	hsa-miR-4429	CLIP-seq
MIRT1006388	hsa-miR-4433	CLIP-seq
MIRT1006389	hsa-miR-4436a	CLIP-seq
MIRT1006390	hsa-miR-4459	CLIP-seq
MIRT1006392	hsa-miR-4474-5p	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006329	hsa-miR-4533	CLIP-seq
MIRT1006398	hsa-miR-4646-5p	CLIP-seq
MIRT1998233	hsa-miR-4653-3p	CLIP-seq
MIRT1006403	hsa-miR-4693-3p	CLIP-seq
MIRT1006405	hsa-miR-4700-3p	CLIP-seq
MIRT1006332	hsa-miR-4701-3p	CLIP-seq
MIRT1006333	hsa-miR-4716-3p	CLIP-seq
MIRT1006334	hsa-miR-4725-3p	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT1006409	hsa-miR-4768-3p	CLIP-seq
MIRT1006337	hsa-miR-4772-5p	CLIP-seq
MIRT1998234	hsa-miR-4796-3p	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT1998235	hsa-miR-520a-5p	CLIP-seq
MIRT1006411	hsa-miR-520d-5p	CLIP-seq
MIRT1998236	hsa-miR-520g	CLIP-seq
MIRT1998237	hsa-miR-520h	CLIP-seq
MIRT1006413	hsa-miR-524-5p	CLIP-seq
MIRT1998238	hsa-miR-525-5p	CLIP-seq
MIRT1006414	hsa-miR-541	CLIP-seq
MIRT1006339	hsa-miR-544b	CLIP-seq
MIRT1006340	hsa-miR-548ac	CLIP-seq
MIRT1006342	hsa-miR-548c-3p	CLIP-seq
MIRT1006343	hsa-miR-548d-3p	CLIP-seq
MIRT1006344	hsa-miR-548z	CLIP-seq
MIRT1998239	hsa-miR-579	CLIP-seq
MIRT1006345	hsa-miR-625	CLIP-seq
MIRT1006422	hsa-miR-654-5p	CLIP-seq
MIRT1006347	hsa-miR-873	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006357	hsa-miR-141	CLIP-seq
MIRT1006360	hsa-miR-200a	CLIP-seq
MIRT1006350	hsa-miR-1225-5p	CLIP-seq
MIRT1006351	hsa-miR-1228	CLIP-seq
MIRT1006297	hsa-miR-1262	CLIP-seq
MIRT1006354	hsa-miR-1285	CLIP-seq
MIRT1006357	hsa-miR-141	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT1006360	hsa-miR-200a	CLIP-seq
MIRT2231822	hsa-miR-2117	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT2231823	hsa-miR-3144-5p	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT2231824	hsa-miR-3180-5p	CLIP-seq
MIRT1006305	hsa-miR-3189-3p	CLIP-seq
MIRT1006306	hsa-miR-3202	CLIP-seq
MIRT1998222	hsa-miR-320a	CLIP-seq
MIRT1998223	hsa-miR-320b	CLIP-seq
MIRT1998224	hsa-miR-320c	CLIP-seq
MIRT1998225	hsa-miR-320d	CLIP-seq
MIRT1006308	hsa-miR-338-3p	CLIP-seq
MIRT1006309	hsa-miR-3609	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006371	hsa-miR-3614-5p	CLIP-seq
MIRT2231825	hsa-miR-3616-3p	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT1006318	hsa-miR-376c	CLIP-seq
MIRT1006319	hsa-miR-383	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1998228	hsa-miR-3926	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT2231826	hsa-miR-4273	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1998231	hsa-miR-4424	CLIP-seq
MIRT1998232	hsa-miR-4429	CLIP-seq
MIRT1006388	hsa-miR-4433	CLIP-seq
MIRT1006389	hsa-miR-4436a	CLIP-seq
MIRT1006390	hsa-miR-4459	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT2231827	hsa-miR-4482	CLIP-seq
MIRT1006397	hsa-miR-4514	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006329	hsa-miR-4533	CLIP-seq
MIRT1006399	hsa-miR-4649-3p	CLIP-seq
MIRT1998233	hsa-miR-4653-3p	CLIP-seq
MIRT1006401	hsa-miR-4679	CLIP-seq
MIRT1006402	hsa-miR-4692	CLIP-seq
MIRT1006403	hsa-miR-4693-3p	CLIP-seq
MIRT1006405	hsa-miR-4700-3p	CLIP-seq
MIRT1006332	hsa-miR-4701-3p	CLIP-seq
MIRT2231828	hsa-miR-4711-5p	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT2231829	hsa-miR-4761-3p	CLIP-seq
MIRT1006409	hsa-miR-4768-3p	CLIP-seq
MIRT2231830	hsa-miR-4768-5p	CLIP-seq
MIRT1006337	hsa-miR-4772-5p	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT2231831	hsa-miR-490-3p	CLIP-seq
MIRT2231832	hsa-miR-499-3p	CLIP-seq
MIRT2231833	hsa-miR-499a-3p	CLIP-seq
MIRT1998235	hsa-miR-520a-5p	CLIP-seq
MIRT1998238	hsa-miR-525-5p	CLIP-seq
MIRT1006339	hsa-miR-544b	CLIP-seq
MIRT1006340	hsa-miR-548ac	CLIP-seq
MIRT1006341	hsa-miR-548ah	CLIP-seq
MIRT1006343	hsa-miR-548d-3p	CLIP-seq
MIRT2231834	hsa-miR-548s	CLIP-seq
MIRT1006344	hsa-miR-548z	CLIP-seq
MIRT1006426	hsa-miR-766	CLIP-seq
MIRT1006347	hsa-miR-873	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006351	hsa-miR-1228	CLIP-seq
MIRT1006353	hsa-miR-1255b	CLIP-seq
MIRT1006297	hsa-miR-1262	CLIP-seq
MIRT1006354	hsa-miR-1285	CLIP-seq
MIRT1006298	hsa-miR-1292	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT1006300	hsa-miR-202	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT2231823	hsa-miR-3144-5p	CLIP-seq
MIRT1006305	hsa-miR-3189-3p	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT2231825	hsa-miR-3616-3p	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT2388248	hsa-miR-3664-5p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT2388249	hsa-miR-3667-5p	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT1006318	hsa-miR-376c	CLIP-seq
MIRT1006319	hsa-miR-383	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT1006322	hsa-miR-4257	CLIP-seq
MIRT1006324	hsa-miR-4275	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1006390	hsa-miR-4459	CLIP-seq
MIRT1006325	hsa-miR-4471	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT1006326	hsa-miR-4506	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006399	hsa-miR-4649-3p	CLIP-seq
MIRT1006401	hsa-miR-4679	CLIP-seq
MIRT1006332	hsa-miR-4701-3p	CLIP-seq
MIRT2231828	hsa-miR-4711-5p	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT2231829	hsa-miR-4761-3p	CLIP-seq
MIRT1006337	hsa-miR-4772-5p	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT1006339	hsa-miR-544b	CLIP-seq
MIRT1006340	hsa-miR-548ac	CLIP-seq
MIRT1006342	hsa-miR-548c-3p	CLIP-seq
MIRT1006343	hsa-miR-548d-3p	CLIP-seq
MIRT1006344	hsa-miR-548z	CLIP-seq
MIRT1006426	hsa-miR-766	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006351	hsa-miR-1228	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT1006308	hsa-miR-338-3p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT1006397	hsa-miR-4514	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006399	hsa-miR-4649-3p	CLIP-seq
MIRT1006401	hsa-miR-4679	CLIP-seq
MIRT1006402	hsa-miR-4692	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006351	hsa-miR-1228	CLIP-seq
MIRT1006354	hsa-miR-1285	CLIP-seq
MIRT2535847	hsa-miR-1323	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT1998219	hsa-miR-2114	CLIP-seq
MIRT2535848	hsa-miR-25	CLIP-seq
MIRT2535849	hsa-miR-3120-5p	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT2535850	hsa-miR-32	CLIP-seq
MIRT2535851	hsa-miR-335	CLIP-seq
MIRT1006308	hsa-miR-338-3p	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT1006373	hsa-miR-3622b-5p	CLIP-seq
MIRT2535852	hsa-miR-363	CLIP-seq
MIRT2388248	hsa-miR-3664-5p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT2388249	hsa-miR-3667-5p	CLIP-seq
MIRT2535853	hsa-miR-367	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT2535854	hsa-miR-371-5p	CLIP-seq
MIRT2535855	hsa-miR-371b-5p	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT1006381	hsa-miR-3945	CLIP-seq
MIRT1006383	hsa-miR-4253	CLIP-seq
MIRT2535856	hsa-miR-4325	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT1006397	hsa-miR-4514	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006399	hsa-miR-4649-3p	CLIP-seq
MIRT1006401	hsa-miR-4679	CLIP-seq
MIRT1006402	hsa-miR-4692	CLIP-seq
MIRT1006403	hsa-miR-4693-3p	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT1006342	hsa-miR-548c-3p	CLIP-seq
MIRT2535857	hsa-miR-548o	CLIP-seq
MIRT2535858	hsa-miR-548p	CLIP-seq
MIRT2535859	hsa-miR-593	CLIP-seq
MIRT1006426	hsa-miR-766	CLIP-seq
MIRT2535860	hsa-miR-890	CLIP-seq
MIRT2535861	hsa-miR-92a	CLIP-seq
MIRT2535862	hsa-miR-92b	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq
MIRT1006351	hsa-miR-1228	CLIP-seq
MIRT1006354	hsa-miR-1285	CLIP-seq
MIRT2535847	hsa-miR-1323	CLIP-seq
MIRT1006359	hsa-miR-1827	CLIP-seq
MIRT2535848	hsa-miR-25	CLIP-seq
MIRT2535849	hsa-miR-3120-5p	CLIP-seq
MIRT1006302	hsa-miR-3122	CLIP-seq
MIRT1006304	hsa-miR-3165	CLIP-seq
MIRT2535850	hsa-miR-32	CLIP-seq
MIRT2535851	hsa-miR-335	CLIP-seq
MIRT1006308	hsa-miR-338-3p	CLIP-seq
MIRT1006310	hsa-miR-3613-3p	CLIP-seq
MIRT1006311	hsa-miR-3622a-3p	CLIP-seq
MIRT1006312	hsa-miR-3622b-3p	CLIP-seq
MIRT1006373	hsa-miR-3622b-5p	CLIP-seq
MIRT2535852	hsa-miR-363	CLIP-seq
MIRT2388248	hsa-miR-3664-5p	CLIP-seq
MIRT1006313	hsa-miR-3665	CLIP-seq
MIRT2388249	hsa-miR-3667-5p	CLIP-seq
MIRT2535853	hsa-miR-367	CLIP-seq
MIRT1006314	hsa-miR-3689a-3p	CLIP-seq
MIRT1006315	hsa-miR-3689c	CLIP-seq
MIRT1006316	hsa-miR-3714	CLIP-seq
MIRT2535854	hsa-miR-371-5p	CLIP-seq
MIRT2535855	hsa-miR-371b-5p	CLIP-seq
MIRT1006320	hsa-miR-3913-5p	CLIP-seq
MIRT1006379	hsa-miR-3929	CLIP-seq
MIRT1006381	hsa-miR-3945	CLIP-seq
MIRT1006383	hsa-miR-4253	CLIP-seq
MIRT2535856	hsa-miR-4325	CLIP-seq
MIRT1006387	hsa-miR-4419b	CLIP-seq
MIRT1006393	hsa-miR-4478	CLIP-seq
MIRT1006397	hsa-miR-4514	CLIP-seq
MIRT1006328	hsa-miR-4530	CLIP-seq
MIRT1006399	hsa-miR-4649-3p	CLIP-seq
MIRT1006401	hsa-miR-4679	CLIP-seq
MIRT1006402	hsa-miR-4692	CLIP-seq
MIRT1006335	hsa-miR-4728-5p	CLIP-seq
MIRT1006336	hsa-miR-4736	CLIP-seq
MIRT1006410	hsa-miR-485-5p	CLIP-seq
MIRT1006342	hsa-miR-548c-3p	CLIP-seq
MIRT2535857	hsa-miR-548o	CLIP-seq
MIRT2535858	hsa-miR-548p	CLIP-seq
MIRT2535859	hsa-miR-593	CLIP-seq
MIRT1006426	hsa-miR-766	CLIP-seq
MIRT2535861	hsa-miR-92a	CLIP-seq
MIRT2535862	hsa-miR-92b	CLIP-seq
MIRT1006348	hsa-miR-940	CLIP-seq

Show/Hide all (3)

Transcription factor	Regulation	Reference
GTF3A	Unknown	12364590
TBP	Repression	19841068
TP53	Unknown	12364590

Show/Hide all (47)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IDA	25453086, 27731383
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	21909421
GO:0003723	Function	RNA binding	EXP	29677513
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IDA	27378374
GO:0003723	Function	RNA binding	IEA
GO:0003723	Function	RNA binding	IPI	38070499
GO:0003723	Function	RNA binding	TAS	8510758
GO:0003730	Function	MRNA 3'-UTR binding	IEA
GO:0005515	Function	Protein binding	IPI	9774382, 16169070, 18509338, 18954305, 20085233, 21988832, 22240165, 22778397, 23152885, 23232809, 23681068, 23975937, 26124092, 27460707, 27615052, 27731383, 30354839, 32814053, 34316702, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	16365397, 21909421, 27731383
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	8510758
GO:0005654	Component	Nucleoplasm	IDA	38070499
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	26124092
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IDA	25453086
GO:0008270	Function	Zinc ion binding	IEA
GO:0008380	Process	RNA splicing	IDA	26124092
GO:0008380	Process	RNA splicing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0010467	Process	Gene expression	IEA
GO:0042802	Function	Identical protein binding	IPI	18509338, 23975937, 29439243, 29610493
GO:0043484	Process	Regulation of RNA splicing	IDA	25453086, 27731383
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048255	Process	MRNA stabilization	IDA	27378374
GO:0051260	Process	Protein homooligomerization	IDA	25453086
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0098982	Component	GABA-ergic synapse	IEA
GO:0099523	Component	Presynaptic cytosol	IEA
GO:0099524	Component	Postsynaptic cytosol	IEA
GO:0140693	Function	Molecular condensate scaffold activity	EXP	38070499
GO:0140693	Function	Molecular condensate scaffold activity	IDA	26317470, 26455390, 29677513, 38070499
GO:0140693	Function	Molecular condensate scaffold activity	IMP	38070499
GO:0140694	Process	Membraneless organelle assembly	IDA	38070499
GO:1905168	Process	Positive regulation of double-strand break repair via homologous recombination	IDA	10567410
GO:1990000	Process	Amyloid fibril formation	EXP	28942918
GO:1990000	Process	Amyloid fibril formation	IDA	22579281

MIM	HGNC	e!Ensembl
137070	4010	ENSG00000089280

P35637

Protein name

RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)

Protein function

DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response (PubMed:27731383). Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3

PDB

2LA6 , 2LCW , 4FDD , 4FQ3 , 5W3N , 5XRR , 5XSG , 5YVG , 5YVH , 5YVI , 6BWZ , 6BXV , 6BZP , 6G99 , 6GBM , 6KJ1 , 6KJ2 , 6KJ3 , 6KJ4 , 6SNJ , 6XFM , 7CYL , 7VQQ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	287 → 365	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00641	zf-RanBP	422 → 453	Zn-finger in Ran binding protein and others	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous.

Sequence

MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ
SQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSS
SYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQD
QSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYE
PRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES
VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFS
GNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQ
QRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYD
RGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY

Sequence length

526

Interactions

View interactions

	KEGG		Reactome
	mRNA surveillance pathway Spliceosome Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Transcriptional misregulation in cancer		mRNA Splicing - Major Pathway

833

Show/Hide Causal Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Amyotrophic lateral sclerosis 6, autosomal recessive	Pathogenic	rs121909667	RCV000017608
Amyotrophic lateral sclerosis type 6	Pathogenic; Likely pathogenic	rs2144142389, rs1596914113, rs2144138894, rs2144140268, rs1596912983, rs2544279075, rs2544251972, rs1555509699, rs2544279181, rs886041390, rs1555509605, rs1555509609, rs2544279594, rs121909668, rs121909669 View all (9 more)	RCV001386161 RCV001808069 RCV002008546 RCV001954906 RCV001956250 RCV003112340 RCV002617179 RCV002913845 RCV003153235 RCV001069729 RCV003455847 RCV003783685 RCV003783686 RCV003800708 RCV000017609 RCV000017610 RCV000017611 RCV000017612 RCV000022556 RCV000022557 RCV000995772 RCV000823358 RCV000989598 RCV001050825 RCV001095436 RCV001095437 RCV001095438 RCV001095435 RCV001201343
FUS-related disorder	Pathogenic; Likely pathogenic	rs1596912983, rs886041390, rs121909668, rs1555509569	RCV004746544 RCV003401225 RCV003421921 RCV004745160 RCV004722855
Juvenile amyotrophic lateral sclerosis	Pathogenic	rs886041390, rs1228194239	RCV001095439 RCV001095440
Tremor, hereditary essential, 4	Pathogenic; Likely pathogenic	rs2144142389, rs2144138894, rs2144140268, rs1596912983, rs2544279075, rs2544251972, rs1555509699, rs886041390, rs1555509605, rs1555509609, rs2544279594, rs121909668, rs121909669, rs121909671, rs387906627 View all (3 more)	RCV001386161 RCV002008546 RCV001954906 RCV001956250 RCV003112340 RCV002617179 RCV002913845 RCV001069729 RCV003783685 RCV003783686 RCV003800708 RCV000703284 RCV005222688 RCV001851894 RCV001851895 RCV003764624 RCV001386160 RCV000030720 RCV000823358 RCV001050825 RCV001386162

Show/Hide Unknown Diseases (28)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign; Likely benign	rs72550862, rs201544187, rs61733962	RCV005915022 RCV005922539 RCV005892795
Adrenocortical carcinoma, hereditary	Benign	rs61733962	RCV005892799
Amyotrophic lateral sclerosis	Conflicting classifications of pathogenicity	rs186547381	RCV003993752
Amyotrophic Lateral Sclerosis, Dominant	Benign; Likely benign; Uncertain significance	rs72550890, rs886051944, rs1216489571, rs753379140, rs572228309, rs1211904015, rs886051957	RCV000273657 RCV000284898 RCV000311065 RCV000342951 RCV000285704 RCV000318806 RCV000304394 RCV000356856
Cervical cancer	Benign; Likely benign	rs72550862, rs61733962	RCV005915024 RCV005892800
Cholangiocarcinoma	Benign; Likely benign	rs72550862, rs61733962	RCV005915031 RCV005892810
Clear cell carcinoma of kidney	Benign	rs61733962	RCV005892801
Colon adenocarcinoma	Benign	rs61733962	RCV005892794
Colorectal cancer	Benign; Uncertain significance	rs755482297, rs369757630	RCV005869718 RCV005931910
Distal spinal muscular atrophy	Uncertain significance	rs1555510151	RCV000664252
Dystonic disorder	Uncertain significance	rs1057518893	RCV000415283
Familial cancer of breast	Benign; Likely benign	rs72550862	RCV005915021
Frontotemporal dementia	Conflicting classifications of pathogenicity	rs186547381	RCV001847624
Gastric cancer	Benign; Likely benign	rs72550862, rs201544187, rs61733962	RCV005915027 RCV005922540 RCV005892804
Hepatocellular carcinoma	Benign	rs61733962	RCV005892796
Lung cancer	Benign; Likely benign; Uncertain significance	rs72550862, rs77839730, rs61733962, rs1596914113	RCV005915032 RCV005931908 RCV005892811 RCV005912172
Malignant lymphoma, large B-cell, diffuse	Benign; Likely benign	rs72550862	RCV005915025
Malignant tumor of esophagus	Benign; Likely benign	rs72550862, rs77839730, rs61733962	RCV005915023 RCV005931905 RCV005892797
Melanoma	Benign	rs61733962	RCV005892809
Myoclonus	Uncertain significance	rs1057518893	RCV000415283
Nonpapillary renal cell carcinoma	Benign	rs61733962	RCV005892798
Ovarian serous cystadenocarcinoma	Benign; Likely benign	rs72550862, rs201544187, rs77839730, rs61733962	RCV005915028 RCV005922541 RCV005931907 RCV005892805
Sarcoma	Benign; Likely benign	rs72550862, rs77839730, rs61733962	RCV005915026 RCV005931906 RCV005892803
Thymoma	Benign; Likely benign	rs72550862, rs61733962	RCV005915030 RCV005892807
Thyroid cancer, nonmedullary, 1	Benign	rs61733962	RCV005892808
Uterine carcinosarcoma	Benign; Likely benign	rs72550862, rs61733962	RCV005915029 RCV005892806
Uterine corpus endometrial carcinoma	Benign; Likely benign	rs72550862, rs72550865, rs201544187, rs77839730, rs61733962	RCV005915033 RCV005922082 RCV005922542 RCV005931909 RCV005892812
Uveal melanoma	Benign	rs61733962	RCV005892802

Show/Hide Text Mining Associations (139)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
AA amyloidosis	Associate	35637421
Adenocarcinoma	Associate	36035281
Adenocarcinoma of Lung	Associate	21151896
Alzheimer Disease	Associate	30367664, 31405128, 32941707
Amyotrophic Lateral Sclerosis	Associate	19669651, 19741216, 20138404, 20232451, 20517935, 20544928, 20577002, 20579074, 20598774, 20668259, 20668261, 20720006, 21074900, 21327870, 21452073 View all (158 more)
Amyotrophic Lateral Sclerosis	Stimulate	34544842
Amyotrophic lateral sclerosis 1	Associate	19450904, 19674978, 19741215, 19741216, 20138404, 20517935, 20544928, 20577002, 20598774, 20668259, 20886222, 21603978, 21604077, 22055719, 23056579 View all (11 more)
Amyotrophic Lateral Sclerosis 2 Juvenile	Associate	34254495
Amyotrophic lateral sclerosis type 6	Associate	22055719, 34587215, 37582053
Atherosclerosis	Associate	37688506
Atrophy	Associate	19946779
Bone Cysts	Associate	34081036
Bone Diseases	Associate	32187044
Bone Neoplasms	Associate	34310785
Breast Neoplasms	Associate	36493359
Carcinogenesis	Associate	22081015, 37887305, 7585257
Carcinoma Hepatocellular	Inhibit	30308519
Carcinoma Squamous Cell	Inhibit	18172250
Chorea	Associate	32116048
Cognition Disorders	Associate	26984092
Colonic Neoplasms	Associate	37597669
Common Variable Immunodeficiency	Associate	25678086
Corticobasal Degeneration	Associate	21943958
Cytomegalovirus Infections	Associate	20886222
Death	Associate	31017923
Dementia	Associate	20517935, 20668259, 28660843, 30530974, 35120450
Demyelinating Diseases	Associate	32217641
Depressive Disorder Major	Associate	37098514
Desmoplastic Small Round Cell Tumor	Associate	22072439, 25010205
Disease	Associate	7585257
Distal myopathy Nonaka type	Associate	34291734
Drug Related Side Effects and Adverse Reactions	Associate	21327870, 21541367, 26056265, 28790177, 31767634, 35194965, 36833445
Drug Related Side Effects and Adverse Reactions	Stimulate	21452073
Dystonic Disorders	Associate	20544928
Endometrial Stromal Tumors	Associate	15640831, 19605340, 20471519, 20499220, 21406083, 21536545, 21691827, 25231134, 28558780, 32164724, 37905642
Ependymoma	Associate	10779324
Epileptic Syndromes	Associate	32678235
Essential Tremor	Associate	22863194, 23601511, 23834483, 25375143, 32196977, 32307925
Fever	Stimulate	33885910
Fibrosarcoma	Associate	20499220, 22388756, 25231134
Fibrosarcoma	Stimulate	21691827
Foot Diseases	Associate	25706482
Frontotemporal Dementia	Associate	19674978, 20668259, 21943958, 22060063, 22692064, 24709683, 26056265, 27632209, 28282387, 28790177, 29677514, 29897835, 31171724, 31630970, 32381627 View all (14 more)
Frontotemporal Lobar Degeneration	Associate	19674978, 19946779, 20490813, 20668261, 20886222, 21327870, 21541367, 21603978, 21604077, 22563080, 22968170, 22993125, 23048034, 23635657, 23925123 View all (14 more)
Fused Kidney	Associate	36965406
Ganglion Cysts	Associate	25650275
Gastrointestinal Stromal Tumors	Associate	25987131
Glioma	Associate	37158824
Glomerulonephritis Membranous	Stimulate	21327870
Heart Diseases	Associate	38105257
Hemangioendothelioma	Associate	30459475
Heredodegenerative Disorders Nervous System	Associate	22460799, 23049996, 23925123, 26573619
Herpes Simplex	Associate	32967368
Histiocytoma Angiomatoid Fibrous	Associate	19801966, 37097347
HIV Infections	Associate	31238957
Hypoxia	Stimulate	36806670
Hypoxia Brain	Stimulate	36806670
Immune System Diseases	Associate	27387891
Inflammation	Associate	27387891, 36276649, 37688506
Inflammation	Stimulate	36653804
Intellectual Disability	Associate	26984092
Kearns Sayre Syndrome	Associate	30659642
Lead Poisoning Nervous System	Associate	31693373
Learning Disabilities	Associate	26984092
Leukemia	Associate	18620564, 20061812, 24068373
Leukemia Erythroblastic Acute	Stimulate	33186348
Leukemia Myeloid	Associate	10779324
Leukemia Myeloid Acute	Associate	10354136, 20061812, 24068373, 26148230, 30150206, 35623083, 9242552
Leukemia Promyelocytic Acute	Associate	17854312, 34404765
Leukemia T Cell	Associate	35182012
Lewy Body Disease	Associate	31405128, 33900085
Lipoma	Associate	25650275
Liposarcoma	Associate	11278855, 18509338, 19841068, 20624952, 20720006, 21169411, 21857683, 22055719, 22460799, 22588557, 23155438, 25444610, 26604682, 30308519, 31092554, 32060318, 35247836, 35733138 View all (3 more)
Liposarcoma Myxoid	Associate	11229517, 12169678, 12876210, 18820664, 20017906, 20581806, 20863376, 22523595, 25393000, 26036639, 29588491, 32341520, 32362012, 32815829, 33731886 View all (7 more)
Liver Neoplasms	Associate	19449021, 20544928, 20624952, 22081015, 26293199, 26452761, 27288402, 27906075, 28790177, 30398641, 30642400, 31017923, 31875556, 32404191, 33269497 View all (10 more)
Lung Neoplasms	Inhibit	18172250
Lung Neoplasms	Associate	19671678, 32808651
Lymphoma Primary Effusion	Inhibit	29986386
Malignant mesenchymal tumor	Associate	33141488, 34821426
Mesothelioma	Associate	35665561, 37400148
Mesothelioma Malignant	Associate	18973227, 28505004
Microphthalmia syndromic 7	Associate	12169678, 20017906, 25393000, 25650275
Mitochondrial Diseases	Associate	32381627, 36163369
Motor Neuron Disease	Associate	19884572, 22081015, 23022481, 24439481, 26452761, 31017923, 31801573, 33580145, 33857636, 34233002, 36834591
Mouth Diseases	Associate	35353344
Movement Disorders	Associate	32307925
Muscle Weakness	Associate	20544928, 33518565
Muscular Atrophy Spinal	Associate	23022481, 23155438, 30398641, 30565205
Myasthenia Gravis	Associate	27387891
Myoclonic Epilepsies Progressive	Associate	30659642
Myoepithelioma	Associate	25706482, 31994243, 32557980, 38266920
Myopathies Nemaline	Associate	20886222
Myopathy desmin storage	Associate	19669651, 20886222, 21603978, 21792670
Myopathy Granulovacuolar Lobular with Electrical Myotonia	Stimulate	30659642
Neoplasm Metastasis	Inhibit	21169411
Neoplasm Metastasis	Associate	25706482
Neoplasms	Inhibit	18172250, 19671678, 21169411
Neoplasms	Associate	18620564, 21151896, 22460799, 24267890, 25501833, 26036639, 26573619, 28505004, 28945358, 29321535, 29588491, 30720533, 32060318, 32191346, 32557980 View all (15 more)
Nerve Degeneration	Associate	24204307, 26123490, 27615052, 31017923
Neuroblastoma	Associate	36833445
Neurodegenerative Diseases	Associate	21327870, 22055719, 22968170, 23048034, 23249733, 23635657, 24013423, 25375143, 25501833, 26124092, 26317470, 29140459, 29362359, 29677514, 29929116 View all (21 more)
Neurodegenerative Diseases	Inhibit	37461319
Neuroectodermal Tumors	Associate	36934861
Neurologic Manifestations	Associate	22060063, 30992467, 38105257
Neuronal intranuclear inclusion disease	Associate	20886222, 38145851
Nevus Epithelioid and Spindle Cell	Associate	35353344
Night blindness congenital stationary	Associate	38105257
Parkinson Disease	Associate	20668259, 24651478, 31171724, 31405128
Peritonitis	Associate	32770123, 35665561
Personality Disorders	Associate	31756779
Pick Disease of the Brain	Associate	20886222, 21603978, 21792670
Plaque Amyloid	Associate	20886222
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	10691862
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Stimulate	17854312
Progressive supranuclear palsy atypical	Associate	20668259
Prostatic Neoplasms	Associate	21169411, 21909421, 31736422, 36035281, 36517760
Protein Aggregation Pathological	Associate	36833445
Proteostasis Deficiencies	Associate	21603978, 31875556, 37115004
Respiratory Insufficiency	Associate	24439481
Rhabdomyosarcoma	Associate	30720533, 33382123, 35353344, 38168093
Sarcoma	Associate	18620564, 20017906, 20720006, 21128778, 22388756, 22460799, 23290535, 25867764, 28701145, 28924037, 29458410, 30040819, 30308519, 30459475, 31092554 View all (10 more)
Sarcoma Clear Cell	Associate	35347249
Sarcoma Ewing	Associate	17620387, 21169411, 25501833, 31756779, 31870501, 32362012, 34465585, 34749732, 37567448, 7485386
Sarcoma Myeloid	Associate	35623083, 36916780
SHORT syndrome	Associate	39596510
Small Cell Lung Carcinoma	Inhibit	18172250
Smooth Muscle Tumor	Associate	38012555
Squamous Cell Carcinoma of Head and Neck	Associate	33618612, 36481914
Stomach Neoplasms	Associate	31591939, 35733138
Tauopathies	Associate	30659642
Thyroid Cancer Papillary	Associate	35599603
Tooth Loss	Associate	28988989
Translocation Genetic	Associate	31092554
Triple Negative Breast Neoplasms	Associate	36806670
Tukel syndrome	Associate	19674978
Urinary Bladder Neoplasms	Associate	36420257
Uterine Cervical Neoplasms	Associate	29909347
Vascular Calcification	Associate	38012555
Vascular Malformation Primary Intraosseous	Associate	30720533, 33382123

FUS (FUS RNA binding protein)