Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23788
Gene name Gene Name - the full gene name approved by the HGNC.	Mitochondrial carrier 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MTCH2
Synonyms (NCBI Gene) Gene synonyms aliases	HSPC032, MIMP, SLC25A50
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies

Show/Hide all(275)

miRTarBase ID	miRNA	Experiments	Reference
MIRT029895	hsa-miR-26b-5p	Microarray	19088304
MIRT051550	hsa-let-7e-5p	CLASH	23622248
MIRT047945	hsa-miR-30c-5p	CLASH	23622248
MIRT042361	hsa-miR-484	CLASH	23622248
MIRT038156	hsa-miR-423-5p	CLASH	23622248
MIRT437877	hsa-miR-135b-5p	Luciferase reporter assay, Western blot	23623609
MIRT1162384	hsa-miR-106a	CLIP-seq
MIRT1162385	hsa-miR-106b	CLIP-seq
MIRT1162386	hsa-miR-1224-5p	CLIP-seq
MIRT1162387	hsa-miR-1256	CLIP-seq
MIRT1162388	hsa-miR-1304	CLIP-seq
MIRT1162389	hsa-miR-150	CLIP-seq
MIRT1162390	hsa-miR-17	CLIP-seq
MIRT1162391	hsa-miR-203	CLIP-seq
MIRT1162392	hsa-miR-20a	CLIP-seq
MIRT1162393	hsa-miR-20b	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT1162396	hsa-miR-2682	CLIP-seq
MIRT1162397	hsa-miR-3121-5p	CLIP-seq
MIRT1162398	hsa-miR-3148	CLIP-seq
MIRT1162399	hsa-miR-3185	CLIP-seq
MIRT1162400	hsa-miR-3192	CLIP-seq
MIRT1162401	hsa-miR-3199	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT1162403	hsa-miR-3613-3p	CLIP-seq
MIRT1162404	hsa-miR-3915	CLIP-seq
MIRT1162405	hsa-miR-3928	CLIP-seq
MIRT1162406	hsa-miR-3940-5p	CLIP-seq
MIRT1162407	hsa-miR-3974	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT1162409	hsa-miR-4314	CLIP-seq
MIRT1162410	hsa-miR-449c	CLIP-seq
MIRT1162411	hsa-miR-4507	CLIP-seq
MIRT1162412	hsa-miR-4528	CLIP-seq
MIRT1162413	hsa-miR-4642	CLIP-seq
MIRT1162414	hsa-miR-4646-5p	CLIP-seq
MIRT1162415	hsa-miR-4653-3p	CLIP-seq
MIRT1162416	hsa-miR-4689	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT1162418	hsa-miR-4713-5p	CLIP-seq
MIRT1162419	hsa-miR-4768-5p	CLIP-seq
MIRT1162420	hsa-miR-4778-5p	CLIP-seq
MIRT1162421	hsa-miR-4802-3p	CLIP-seq
MIRT1162422	hsa-miR-499a-5p	CLIP-seq
MIRT1162423	hsa-miR-519d	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT1162426	hsa-miR-532-3p	CLIP-seq
MIRT1162427	hsa-miR-543	CLIP-seq
MIRT1162428	hsa-miR-545	CLIP-seq
MIRT1162429	hsa-miR-548a-3p	CLIP-seq
MIRT1162430	hsa-miR-548ae	CLIP-seq
MIRT1162431	hsa-miR-548aj	CLIP-seq
MIRT1162432	hsa-miR-548am	CLIP-seq
MIRT1162433	hsa-miR-548e	CLIP-seq
MIRT1162434	hsa-miR-548f	CLIP-seq
MIRT1162435	hsa-miR-548m	CLIP-seq
MIRT1162436	hsa-miR-548t	CLIP-seq
MIRT1162437	hsa-miR-548x	CLIP-seq
MIRT1162438	hsa-miR-624	CLIP-seq
MIRT1162439	hsa-miR-93	CLIP-seq
MIRT1162440	hsa-miR-940	CLIP-seq
MIRT2046572	hsa-miR-1208	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT2046573	hsa-miR-3140-5p	CLIP-seq
MIRT1162400	hsa-miR-3192	CLIP-seq
MIRT1162401	hsa-miR-3199	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT2046574	hsa-miR-3622a-3p	CLIP-seq
MIRT2046575	hsa-miR-3622b-3p	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT1162409	hsa-miR-4314	CLIP-seq
MIRT1162414	hsa-miR-4646-5p	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT2046576	hsa-miR-579	CLIP-seq
MIRT2046577	hsa-miR-606	CLIP-seq
MIRT2046578	hsa-miR-668	CLIP-seq
MIRT1162384	hsa-miR-106a	CLIP-seq
MIRT1162385	hsa-miR-106b	CLIP-seq
MIRT2046572	hsa-miR-1208	CLIP-seq
MIRT1162386	hsa-miR-1224-5p	CLIP-seq
MIRT2275684	hsa-miR-1271	CLIP-seq
MIRT1162388	hsa-miR-1304	CLIP-seq
MIRT1162389	hsa-miR-150	CLIP-seq
MIRT1162390	hsa-miR-17	CLIP-seq
MIRT2275685	hsa-miR-182	CLIP-seq
MIRT2275686	hsa-miR-186	CLIP-seq
MIRT1162392	hsa-miR-20a	CLIP-seq
MIRT1162393	hsa-miR-20b	CLIP-seq
MIRT2275687	hsa-miR-302a	CLIP-seq
MIRT2275688	hsa-miR-302b	CLIP-seq
MIRT2275689	hsa-miR-302c	CLIP-seq
MIRT2275690	hsa-miR-302d	CLIP-seq
MIRT2275691	hsa-miR-302e	CLIP-seq
MIRT1162397	hsa-miR-3121-5p	CLIP-seq
MIRT2275692	hsa-miR-3133	CLIP-seq
MIRT1162398	hsa-miR-3148	CLIP-seq
MIRT2275693	hsa-miR-3154	CLIP-seq
MIRT2275694	hsa-miR-3174	CLIP-seq
MIRT2275695	hsa-miR-3179	CLIP-seq
MIRT1162400	hsa-miR-3192	CLIP-seq
MIRT1162401	hsa-miR-3199	CLIP-seq
MIRT2275696	hsa-miR-372	CLIP-seq
MIRT2275697	hsa-miR-373	CLIP-seq
MIRT1162404	hsa-miR-3915	CLIP-seq
MIRT1162405	hsa-miR-3928	CLIP-seq
MIRT2275698	hsa-miR-410	CLIP-seq
MIRT2275699	hsa-miR-4268	CLIP-seq
MIRT1162409	hsa-miR-4314	CLIP-seq
MIRT2275700	hsa-miR-4424	CLIP-seq
MIRT2275701	hsa-miR-4503	CLIP-seq
MIRT2275702	hsa-miR-4511	CLIP-seq
MIRT1162414	hsa-miR-4646-5p	CLIP-seq
MIRT1162416	hsa-miR-4689	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT1162418	hsa-miR-4713-5p	CLIP-seq
MIRT1162419	hsa-miR-4768-5p	CLIP-seq
MIRT1162420	hsa-miR-4778-5p	CLIP-seq
MIRT2275703	hsa-miR-519a	CLIP-seq
MIRT2275704	hsa-miR-519b-3p	CLIP-seq
MIRT2275705	hsa-miR-519c-3p	CLIP-seq
MIRT1162423	hsa-miR-519d	CLIP-seq
MIRT2275706	hsa-miR-520a-3p	CLIP-seq
MIRT2275707	hsa-miR-520b	CLIP-seq
MIRT2275708	hsa-miR-520c-3p	CLIP-seq
MIRT2275709	hsa-miR-520d-3p	CLIP-seq
MIRT2275710	hsa-miR-520e	CLIP-seq
MIRT2275711	hsa-miR-520f	CLIP-seq
MIRT1162426	hsa-miR-532-3p	CLIP-seq
MIRT1162427	hsa-miR-543	CLIP-seq
MIRT1162436	hsa-miR-548t	CLIP-seq
MIRT2275712	hsa-miR-550b	CLIP-seq
MIRT2275713	hsa-miR-556-5p	CLIP-seq
MIRT2046576	hsa-miR-579	CLIP-seq
MIRT2046578	hsa-miR-668	CLIP-seq
MIRT2275714	hsa-miR-760	CLIP-seq
MIRT2275715	hsa-miR-890	CLIP-seq
MIRT1162439	hsa-miR-93	CLIP-seq
MIRT2275716	hsa-miR-96	CLIP-seq
MIRT2574612	hsa-miR-1182	CLIP-seq
MIRT2574613	hsa-miR-1245	CLIP-seq
MIRT2574614	hsa-miR-1915	CLIP-seq
MIRT2574615	hsa-miR-2053	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT2574616	hsa-miR-2909	CLIP-seq
MIRT2574617	hsa-miR-3120-5p	CLIP-seq
MIRT2574618	hsa-miR-3150a-5p	CLIP-seq
MIRT2574619	hsa-miR-3150b-5p	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT2574620	hsa-miR-3545-3p	CLIP-seq
MIRT2574621	hsa-miR-3591-5p	CLIP-seq
MIRT2574622	hsa-miR-3606	CLIP-seq
MIRT2574623	hsa-miR-361-5p	CLIP-seq
MIRT2574624	hsa-miR-3616-5p	CLIP-seq
MIRT2574625	hsa-miR-3617	CLIP-seq
MIRT2574626	hsa-miR-3647-5p	CLIP-seq
MIRT2574627	hsa-miR-3673	CLIP-seq
MIRT2574628	hsa-miR-377	CLIP-seq
MIRT2574629	hsa-miR-3908	CLIP-seq
MIRT2574630	hsa-miR-3913-3p	CLIP-seq
MIRT2574631	hsa-miR-3942-5p	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT2275699	hsa-miR-4268	CLIP-seq
MIRT2574632	hsa-miR-432	CLIP-seq
MIRT2275701	hsa-miR-4503	CLIP-seq
MIRT2574633	hsa-miR-450b-5p	CLIP-seq
MIRT2574634	hsa-miR-4635	CLIP-seq
MIRT2574635	hsa-miR-4703-5p	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT2574636	hsa-miR-4725-5p	CLIP-seq
MIRT2574637	hsa-miR-4728-5p	CLIP-seq
MIRT2574638	hsa-miR-4760-3p	CLIP-seq
MIRT2574639	hsa-miR-4766-3p	CLIP-seq
MIRT2574640	hsa-miR-4775	CLIP-seq
MIRT1162422	hsa-miR-499a-5p	CLIP-seq
MIRT2574641	hsa-miR-504	CLIP-seq
MIRT2574642	hsa-miR-516a-3p	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT2574643	hsa-miR-526b	CLIP-seq
MIRT2574644	hsa-miR-548a-5p	CLIP-seq
MIRT2574645	hsa-miR-548ab	CLIP-seq
MIRT2574646	hsa-miR-548ak	CLIP-seq
MIRT2574647	hsa-miR-548b-5p	CLIP-seq
MIRT2574648	hsa-miR-548c-5p	CLIP-seq
MIRT2574649	hsa-miR-548d-5p	CLIP-seq
MIRT2574650	hsa-miR-548h	CLIP-seq
MIRT2574651	hsa-miR-548i	CLIP-seq
MIRT2574652	hsa-miR-548j	CLIP-seq
MIRT2574653	hsa-miR-548n	CLIP-seq
MIRT2574654	hsa-miR-548w	CLIP-seq
MIRT2574655	hsa-miR-548y	CLIP-seq
MIRT2574656	hsa-miR-556-3p	CLIP-seq
MIRT2275713	hsa-miR-556-5p	CLIP-seq
MIRT2574657	hsa-miR-559	CLIP-seq
MIRT2574658	hsa-miR-573	CLIP-seq
MIRT2574659	hsa-miR-578	CLIP-seq
MIRT2574660	hsa-miR-641	CLIP-seq
MIRT2574661	hsa-miR-656	CLIP-seq
MIRT2574662	hsa-miR-921	CLIP-seq
MIRT2574663	hsa-miR-944	CLIP-seq
MIRT2574612	hsa-miR-1182	CLIP-seq
MIRT2574613	hsa-miR-1245	CLIP-seq
MIRT2275686	hsa-miR-186	CLIP-seq
MIRT2574614	hsa-miR-1915	CLIP-seq
MIRT2574615	hsa-miR-2053	CLIP-seq
MIRT1162394	hsa-miR-24	CLIP-seq
MIRT1162395	hsa-miR-2467-5p	CLIP-seq
MIRT2574616	hsa-miR-2909	CLIP-seq
MIRT2574617	hsa-miR-3120-5p	CLIP-seq
MIRT2275692	hsa-miR-3133	CLIP-seq
MIRT2574618	hsa-miR-3150a-5p	CLIP-seq
MIRT2574619	hsa-miR-3150b-5p	CLIP-seq
MIRT2275693	hsa-miR-3154	CLIP-seq
MIRT2275695	hsa-miR-3179	CLIP-seq
MIRT1162402	hsa-miR-339-5p	CLIP-seq
MIRT2574620	hsa-miR-3545-3p	CLIP-seq
MIRT2574621	hsa-miR-3591-5p	CLIP-seq
MIRT2574622	hsa-miR-3606	CLIP-seq
MIRT2574624	hsa-miR-3616-5p	CLIP-seq
MIRT2574625	hsa-miR-3617	CLIP-seq
MIRT2574626	hsa-miR-3647-5p	CLIP-seq
MIRT2574627	hsa-miR-3673	CLIP-seq
MIRT2574628	hsa-miR-377	CLIP-seq
MIRT2574629	hsa-miR-3908	CLIP-seq
MIRT2574630	hsa-miR-3913-3p	CLIP-seq
MIRT2574631	hsa-miR-3942-5p	CLIP-seq
MIRT1162408	hsa-miR-4257	CLIP-seq
MIRT2275699	hsa-miR-4268	CLIP-seq
MIRT2574632	hsa-miR-432	CLIP-seq
MIRT2685452	hsa-miR-4470	CLIP-seq
MIRT2685453	hsa-miR-4494	CLIP-seq
MIRT2685454	hsa-miR-4499	CLIP-seq
MIRT2275701	hsa-miR-4503	CLIP-seq
MIRT2574633	hsa-miR-450b-5p	CLIP-seq
MIRT2574634	hsa-miR-4635	CLIP-seq
MIRT2574635	hsa-miR-4703-5p	CLIP-seq
MIRT1162417	hsa-miR-4712-3p	CLIP-seq
MIRT2574636	hsa-miR-4725-5p	CLIP-seq
MIRT2574637	hsa-miR-4728-5p	CLIP-seq
MIRT2574638	hsa-miR-4760-3p	CLIP-seq
MIRT2574639	hsa-miR-4766-3p	CLIP-seq
MIRT2574640	hsa-miR-4775	CLIP-seq
MIRT1162422	hsa-miR-499a-5p	CLIP-seq
MIRT2574641	hsa-miR-504	CLIP-seq
MIRT2574642	hsa-miR-516a-3p	CLIP-seq
MIRT1162424	hsa-miR-520d-5p	CLIP-seq
MIRT1162425	hsa-miR-524-5p	CLIP-seq
MIRT2574643	hsa-miR-526b	CLIP-seq
MIRT2574644	hsa-miR-548a-5p	CLIP-seq
MIRT2574645	hsa-miR-548ab	CLIP-seq
MIRT2574646	hsa-miR-548ak	CLIP-seq
MIRT2574647	hsa-miR-548b-5p	CLIP-seq
MIRT2574648	hsa-miR-548c-5p	CLIP-seq
MIRT2574649	hsa-miR-548d-5p	CLIP-seq
MIRT2574650	hsa-miR-548h	CLIP-seq
MIRT2574651	hsa-miR-548i	CLIP-seq
MIRT2574652	hsa-miR-548j	CLIP-seq
MIRT2574653	hsa-miR-548n	CLIP-seq
MIRT2574654	hsa-miR-548w	CLIP-seq
MIRT2574655	hsa-miR-548y	CLIP-seq
MIRT2574656	hsa-miR-556-3p	CLIP-seq
MIRT2275713	hsa-miR-556-5p	CLIP-seq
MIRT2574657	hsa-miR-559	CLIP-seq
MIRT2574658	hsa-miR-573	CLIP-seq
MIRT2574659	hsa-miR-578	CLIP-seq
MIRT2574660	hsa-miR-641	CLIP-seq
MIRT2275714	hsa-miR-760	CLIP-seq
MIRT2275715	hsa-miR-890	CLIP-seq
MIRT2574662	hsa-miR-921	CLIP-seq
MIRT2574663	hsa-miR-944	CLIP-seq

Show/Hide all(36)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IDA	36264797
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0006089	Process	Lactate metabolic process	IEA
GO:0006839	Process	Mitochondrial transport	IEA
GO:0010635	Process	Regulation of mitochondrial fusion	IEA
GO:0010635	Process	Regulation of mitochondrial fusion	ISS
GO:0010917	Process	Negative regulation of mitochondrial membrane potential	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0032977	Function	Membrane insertase activity	IDA	36264797
GO:0035701	Process	Hematopoietic stem cell migration	IEA
GO:0042775	Process	Mitochondrial ATP synthesis coupled electron transport	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IBA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	ISS
GO:0045040	Process	Protein insertion into mitochondrial outer membrane	IDA	36264797
GO:0045820	Process	Negative regulation of glycolytic process	IEA
GO:0055088	Process	Lipid homeostasis	IEA
GO:0055088	Process	Lipid homeostasis	ISS
GO:0061484	Process	Hematopoietic stem cell homeostasis	IEA
GO:0070585	Process	Protein localization to mitochondrion	IEA
GO:0070585	Process	Protein localization to mitochondrion	IMP	23744079
GO:0071478	Process	Cellular response to radiation	IEA
GO:0090151	Process	Establishment of protein localization to mitochondrial membrane	IEA
GO:0090152	Process	Establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	IEA
GO:0097284	Process	Hepatocyte apoptotic process	IEA
GO:1902108	Process	Regulation of mitochondrial membrane permeability involved in apoptotic process	IEA
GO:1902231	Process	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	IEA
GO:2000738	Process	Positive regulation of stem cell differentiation	IEA
GO:2000738	Process	Positive regulation of stem cell differentiation	ISS

MIM	HGNC	e!Ensembl
613221	17587	ENSG00000109919

Protein

UniProt ID

Q9Y6C9

Protein name

Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein)

Protein function

Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and mul

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00153	Mito_carr	118 → 205	Mitochondrial carrier protein	Family

Sequence

MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFSYAQH
IASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHV
IKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIITIYREEGILGFFA
GLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLV
SNLMAVNNCGLAGGCPPYSPIYTSWIDCWCMLQKEGNMSRGNSLFFRKVPFGKTYCCDLK
MLI

Sequence length

303

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes with ophthalmic manifestations (PheCode 250.23)	N/A	N/A	GWAS
Hypertension	Hypertension	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS
Neuroticism	Neuroticism	N/A	N/A	GWAS

Show/Hide Text Mining Associations (13)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Abdominal Injuries	Associate	31167208
Alzheimer Disease	Associate	26919393, 33947463
Cardiovascular Diseases	Associate	19910641
Diabetes Mellitus Type 2	Associate	32228543
Feeding and Eating Disorders	Associate	23929626
Glioma	Associate	40018930
Leukemia Myeloid	Associate	34463267
Myofibroma	Associate	33830670
Neoplasms	Stimulate	33299884
Neoplasms	Associate	34437390, 35459861, 40018930
Neoplasms Adipose Tissue	Associate	19692490
Obesity	Associate	19164386, 19692490, 19910641, 19910938, 21976109, 22456663, 23349760, 23950976, 28025578, 31167208, 32228543, 33299884
Weight Loss	Associate	22179955

MTCH2 (mitochondrial carrier 2)