Gene Gene information from NCBI Gene database.
Entrez ID 23760
Gene name Phosphatidylinositol transfer protein beta
Gene symbol PITPNB
Synonyms (NCBI Gene)
PI-TP-betaPtdInsTPVIB1B
Chromosome 22
Chromosome location 22q12.1
Summary This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endopl
miRNA miRNA information provided by mirtarbase database.
841
miRTarBase ID miRNA Experiments Reference
MIRT016434 hsa-miR-193b-3p Microarray 20304954
MIRT021667 hsa-miR-140-3p Sequencing 20371350
MIRT024573 hsa-miR-215-5p Microarray 19074876
MIRT025104 hsa-miR-181a-5p Sequencing 20371350
MIRT026369 hsa-miR-192-5p Microarray 19074876
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
39
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000139 Component Golgi membrane ISS
GO:0000139 Component Golgi membrane TAS
GO:0005515 Function Protein binding IPI 32814053
GO:0005548 Function Phospholipid transporter activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606876 9002 ENSG00000180957
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P48739
Protein name Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta)
Protein function Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (PubMed:10531358, PubMed:18636990, PubMed:20332109). Also catalyzes the transfer of sphingomyelin (By similarity). Required for COPI-mediated retrograde tra
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02121 IP_trans 2 252 Phosphatidylinositol transfer protein Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed in various tissues including brain.
Sequence
Sequence length 271
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    PI and PC transport between ER and Golgi membranes