SDF2L1 (stromal cell derived factor 2 like 1)

Gene

• Entrez ID: 23753
• Gene name: Stromal cell derived factor 2 like 1
• Gene symbol: SDF2L1
• Synonyms (NCBI Gene): -
• Chromosome: 22
• Chromosome location: 22q11.21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018061	hsa-miR-335-5p	Microarray	18185580
MIRT022774	hsa-miR-124-3p	Microarray	18668037
MIRT047950	hsa-miR-30c-5p	CLASH	23622248
MIRT1331686	hsa-miR-1224-3p	CLIP-seq
MIRT1331687	hsa-miR-1224-5p	CLIP-seq
MIRT1331688	hsa-miR-124	CLIP-seq
MIRT1331689	hsa-miR-1283	CLIP-seq
MIRT1331690	hsa-miR-1291	CLIP-seq
MIRT1331691	hsa-miR-3158-5p	CLIP-seq
MIRT1331692	hsa-miR-3166	CLIP-seq
MIRT1331693	hsa-miR-3173-5p	CLIP-seq
MIRT1331694	hsa-miR-328	CLIP-seq
MIRT1331695	hsa-miR-34b	CLIP-seq
MIRT1331696	hsa-miR-3677-5p	CLIP-seq
MIRT1331697	hsa-miR-3915	CLIP-seq
MIRT1331698	hsa-miR-4480	CLIP-seq
MIRT1331699	hsa-miR-4689	CLIP-seq
MIRT1331700	hsa-miR-4715-3p	CLIP-seq
MIRT1331701	hsa-miR-4719	CLIP-seq
MIRT1331702	hsa-miR-4722-3p	CLIP-seq
MIRT1331703	hsa-miR-4727-5p	CLIP-seq
MIRT1331704	hsa-miR-4751	CLIP-seq
MIRT1331705	hsa-miR-4758-3p	CLIP-seq
MIRT1331706	hsa-miR-4769-3p	CLIP-seq
MIRT1331707	hsa-miR-4771	CLIP-seq
MIRT1331708	hsa-miR-506	CLIP-seq
MIRT1331709	hsa-miR-543	CLIP-seq
MIRT1331710	hsa-miR-548an	CLIP-seq
MIRT1331711	hsa-miR-593	CLIP-seq
MIRT1331712	hsa-miR-663b	CLIP-seq
MIRT1331700	hsa-miR-4715-3p	CLIP-seq
MIRT1331687	hsa-miR-1224-5p	CLIP-seq
MIRT1331688	hsa-miR-124	CLIP-seq
MIRT1331689	hsa-miR-1283	CLIP-seq
MIRT1331695	hsa-miR-34b	CLIP-seq
MIRT1331697	hsa-miR-3915	CLIP-seq
MIRT1331699	hsa-miR-4689	CLIP-seq
MIRT1331701	hsa-miR-4719	CLIP-seq
MIRT1331704	hsa-miR-4751	CLIP-seq
MIRT1331708	hsa-miR-506	CLIP-seq
MIRT1331710	hsa-miR-548an	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005783	Component	Endoplasmic reticulum	IDA	28597544
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	IEA
GO:0016020	Component	Membrane	IEA
GO:0034663	Component	Endoplasmic reticulum chaperone complex	IEA
GO:0034976	Process	Response to endoplasmic reticulum stress	IEA
GO:0036503	Process	ERAD pathway	IEA
GO:0042026	Process	Protein refolding	IMP	28597544
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0051087	Function	Protein-folding chaperone binding	IEA
GO:0051117	Function	ATPase binding	IEA
GO:0051787	Function	Misfolded protein binding	IDA	28597544
GO:0051787	Function	Misfolded protein binding	IEA
GO:0071218	Process	Cellular response to misfolded protein	IEA
GO:0101031	Component	Protein folding chaperone complex	IEA
GO:0101031	Component	Protein folding chaperone complex	IPI	28597544

Other IDs

• MIM: 607551
• HGNC: 10676
• e!Ensembl: ENSG00000128228

Protein

• UniProt ID: Q9HCN8
• Protein name: Stromal cell-derived factor 2-like protein 1 (SDF2-like protein 1) (PWP1-interacting protein 8)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02815	MIR	43 → 177	MIR domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed with high expression in testis, moderate expression in the pancreas, spleen, prostate, small intestine and colon. Very low expression is seen in brain and skeletal muscle. {ECO:0000269|PubMed:11162531}.
• Sequence:

  MWSAGRGGAAWPVLLGLLLALLVPGGGAAKTGAELVTCGSVLKLLNTHHRVRLHSHDIKY
  GSGSGQQSVTGVEASDDANSYWRIRGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHF
  PSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGS
  PIRGQHEVHGMPSANTHNTWKAMEGIFIKPSVEPSAGHDEL

• Sequence length: 221

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Associated diseases

Unknown
Disease merge term	Disease name	Evidence	References	Source
Atrial Fibrillation	Atrial fibrillation	N/A	N/A	GWAS
Rheumatoid arthritis	Rheumatoid arthritis	N/A	N/A	GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Breast Neoplasms	Associate	19513569
Nasopharyngeal Carcinoma	Associate	33134371
Neoplasms	Inhibit	33134371