Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23729
Gene name Gene Name - the full gene name approved by the HGNC.	Sedoheptulokinase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SHPK
Synonyms (NCBI Gene) Gene synonyms aliases	CARKL, SHK
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17p13.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene

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SNP ID	Visualize variation	Clinical significance	Consequence
rs144071313	G>A,C	Affects	Coding sequence variant, missense variant, stop gained
rs748544120	C>A,G,T	Affects	Coding sequence variant, stop gained, missense variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT022509	hsa-miR-124-3p	Microarray	18668037
MIRT039817	hsa-miR-615-3p	CLASH	23622248
MIRT039817	hsa-miR-615-3p	CLASH	23622248
MIRT638050	hsa-miR-452-5p	HITS-CLIP	23824327
MIRT638049	hsa-miR-4676-3p	HITS-CLIP	23824327
MIRT638048	hsa-miR-892c-3p	HITS-CLIP	23824327
MIRT638047	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT638046	hsa-miR-943	HITS-CLIP	23824327
MIRT638045	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT638044	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT638043	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT638042	hsa-miR-5096	HITS-CLIP	23824327
MIRT638050	hsa-miR-452-5p	HITS-CLIP	23824327
MIRT638049	hsa-miR-4676-3p	HITS-CLIP	23824327
MIRT638048	hsa-miR-892c-3p	HITS-CLIP	23824327
MIRT638047	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT638046	hsa-miR-943	HITS-CLIP	23824327
MIRT638045	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT638044	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT638043	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT638042	hsa-miR-5096	HITS-CLIP	23824327
MIRT638041	hsa-miR-6728-3p	HITS-CLIP	23824327
MIRT638040	hsa-miR-3670	HITS-CLIP	23824327
MIRT638038	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT638039	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT638037	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT638036	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT638035	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT638034	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT638033	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT638050	hsa-miR-452-5p	HITS-CLIP	23824327
MIRT638049	hsa-miR-4676-3p	HITS-CLIP	23824327
MIRT638048	hsa-miR-892c-3p	HITS-CLIP	23824327
MIRT638047	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT638046	hsa-miR-943	HITS-CLIP	23824327
MIRT638045	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT638044	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT638043	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT638042	hsa-miR-5096	HITS-CLIP	23824327
MIRT638050	hsa-miR-452-5p	HITS-CLIP	23824327
MIRT638049	hsa-miR-4676-3p	HITS-CLIP	23824327
MIRT638048	hsa-miR-892c-3p	HITS-CLIP	23824327
MIRT638047	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT638046	hsa-miR-943	HITS-CLIP	23824327
MIRT638045	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT638044	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT638043	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT638042	hsa-miR-5096	HITS-CLIP	23824327
MIRT638041	hsa-miR-6728-3p	HITS-CLIP	23824327
MIRT638040	hsa-miR-3670	HITS-CLIP	23824327
MIRT638038	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT638039	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT638037	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT638036	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT638035	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT638034	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT638033	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT1347612	hsa-miR-103a	CLIP-seq
MIRT1347613	hsa-miR-107	CLIP-seq
MIRT1347614	hsa-miR-1200	CLIP-seq
MIRT1347615	hsa-miR-122	CLIP-seq
MIRT1347616	hsa-miR-1234	CLIP-seq
MIRT1347617	hsa-miR-1254	CLIP-seq
MIRT1347618	hsa-miR-130a	CLIP-seq
MIRT1347619	hsa-miR-130b	CLIP-seq
MIRT1347620	hsa-miR-134	CLIP-seq
MIRT1347621	hsa-miR-136	CLIP-seq
MIRT1347622	hsa-miR-183	CLIP-seq
MIRT1347623	hsa-miR-1908	CLIP-seq
MIRT1347624	hsa-miR-1911	CLIP-seq
MIRT1347625	hsa-miR-1976	CLIP-seq
MIRT1347626	hsa-miR-2110	CLIP-seq
MIRT1347627	hsa-miR-2467-5p	CLIP-seq
MIRT1347628	hsa-miR-301a	CLIP-seq
MIRT1347629	hsa-miR-301b	CLIP-seq
MIRT1347630	hsa-miR-3116	CLIP-seq
MIRT1347631	hsa-miR-3118	CLIP-seq
MIRT1347632	hsa-miR-3135b	CLIP-seq
MIRT1347633	hsa-miR-3136-3p	CLIP-seq
MIRT1347634	hsa-miR-3136-5p	CLIP-seq
MIRT1347635	hsa-miR-3177-3p	CLIP-seq
MIRT1347636	hsa-miR-3182	CLIP-seq
MIRT1347637	hsa-miR-3188	CLIP-seq
MIRT1347638	hsa-miR-3194-3p	CLIP-seq
MIRT1347639	hsa-miR-324-5p	CLIP-seq
MIRT1347640	hsa-miR-34b	CLIP-seq
MIRT1347641	hsa-miR-3652	CLIP-seq
MIRT1347642	hsa-miR-3666	CLIP-seq
MIRT1347643	hsa-miR-3690	CLIP-seq
MIRT1347644	hsa-miR-3929	CLIP-seq
MIRT1347645	hsa-miR-3944-5p	CLIP-seq
MIRT1347646	hsa-miR-3975	CLIP-seq
MIRT1347647	hsa-miR-4271	CLIP-seq
MIRT1347648	hsa-miR-4292	CLIP-seq
MIRT1347649	hsa-miR-4295	CLIP-seq
MIRT1347650	hsa-miR-4303	CLIP-seq
MIRT1347651	hsa-miR-4308	CLIP-seq
MIRT1347652	hsa-miR-431	CLIP-seq
MIRT1347653	hsa-miR-4324	CLIP-seq
MIRT1347654	hsa-miR-4419b	CLIP-seq
MIRT1347655	hsa-miR-4430	CLIP-seq
MIRT1347656	hsa-miR-4439	CLIP-seq
MIRT1347657	hsa-miR-4478	CLIP-seq
MIRT1347658	hsa-miR-4493	CLIP-seq
MIRT1347659	hsa-miR-4513	CLIP-seq
MIRT1347660	hsa-miR-451b	CLIP-seq
MIRT1347661	hsa-miR-454	CLIP-seq
MIRT1347662	hsa-miR-4634	CLIP-seq
MIRT1347663	hsa-miR-4649-3p	CLIP-seq
MIRT1347664	hsa-miR-4663	CLIP-seq
MIRT1347665	hsa-miR-4685-5p	CLIP-seq
MIRT1347666	hsa-miR-4694-3p	CLIP-seq
MIRT1347667	hsa-miR-4706	CLIP-seq
MIRT1347668	hsa-miR-4724-5p	CLIP-seq
MIRT1347669	hsa-miR-4725-3p	CLIP-seq
MIRT1347670	hsa-miR-4749-5p	CLIP-seq
MIRT1347671	hsa-miR-4764-5p	CLIP-seq
MIRT1347672	hsa-miR-485-5p	CLIP-seq
MIRT1347673	hsa-miR-491-5p	CLIP-seq
MIRT1347674	hsa-miR-544	CLIP-seq
MIRT1347675	hsa-miR-544b	CLIP-seq
MIRT1347676	hsa-miR-564	CLIP-seq
MIRT1347677	hsa-miR-652	CLIP-seq
MIRT1347678	hsa-miR-663	CLIP-seq
MIRT1347679	hsa-miR-665	CLIP-seq
MIRT1347680	hsa-miR-887	CLIP-seq
MIRT1347681	hsa-miR-924	CLIP-seq
MIRT1347682	hsa-miR-939	CLIP-seq
MIRT1347636	hsa-miR-3182	CLIP-seq
MIRT1347650	hsa-miR-4303	CLIP-seq
MIRT1347664	hsa-miR-4663	CLIP-seq
MIRT1347671	hsa-miR-4764-5p	CLIP-seq
MIRT1347674	hsa-miR-544	CLIP-seq
MIRT1347679	hsa-miR-665	CLIP-seq
MIRT1347636	hsa-miR-3182	CLIP-seq
MIRT1347612	hsa-miR-103a	CLIP-seq
MIRT1347613	hsa-miR-107	CLIP-seq
MIRT1347614	hsa-miR-1200	CLIP-seq
MIRT1347615	hsa-miR-122	CLIP-seq
MIRT2102924	hsa-miR-124	CLIP-seq
MIRT2102925	hsa-miR-1245b-3p	CLIP-seq
MIRT2102926	hsa-miR-1255a	CLIP-seq
MIRT2102927	hsa-miR-1255b	CLIP-seq
MIRT2102928	hsa-miR-1260	CLIP-seq
MIRT2102929	hsa-miR-1260b	CLIP-seq
MIRT1347618	hsa-miR-130a	CLIP-seq
MIRT1347619	hsa-miR-130b	CLIP-seq
MIRT2102930	hsa-miR-140-3p	CLIP-seq
MIRT2102931	hsa-miR-188-3p	CLIP-seq
MIRT1347624	hsa-miR-1911	CLIP-seq
MIRT1347625	hsa-miR-1976	CLIP-seq
MIRT1347627	hsa-miR-2467-5p	CLIP-seq
MIRT2102932	hsa-miR-25	CLIP-seq
MIRT1347628	hsa-miR-301a	CLIP-seq
MIRT1347629	hsa-miR-301b	CLIP-seq
MIRT2102933	hsa-miR-3074-5p	CLIP-seq
MIRT2102934	hsa-miR-3119	CLIP-seq
MIRT1347632	hsa-miR-3135b	CLIP-seq
MIRT2102935	hsa-miR-3153	CLIP-seq
MIRT2102936	hsa-miR-3156-3p	CLIP-seq
MIRT2102937	hsa-miR-3162-3p	CLIP-seq
MIRT1347636	hsa-miR-3182	CLIP-seq
MIRT1347637	hsa-miR-3188	CLIP-seq
MIRT1347638	hsa-miR-3194-3p	CLIP-seq
MIRT2102938	hsa-miR-32	CLIP-seq
MIRT1347640	hsa-miR-34b	CLIP-seq
MIRT2102939	hsa-miR-3529	CLIP-seq
MIRT2102940	hsa-miR-3591-3p	CLIP-seq
MIRT2102941	hsa-miR-363	CLIP-seq
MIRT2102942	hsa-miR-3650	CLIP-seq
MIRT1347641	hsa-miR-3652	CLIP-seq
MIRT1347642	hsa-miR-3666	CLIP-seq
MIRT2102943	hsa-miR-367	CLIP-seq
MIRT2102944	hsa-miR-3672	CLIP-seq
MIRT1347643	hsa-miR-3690	CLIP-seq
MIRT2102945	hsa-miR-370	CLIP-seq
MIRT2102946	hsa-miR-379	CLIP-seq
MIRT1347644	hsa-miR-3929	CLIP-seq
MIRT1347646	hsa-miR-3975	CLIP-seq
MIRT2102947	hsa-miR-4254	CLIP-seq
MIRT1347649	hsa-miR-4295	CLIP-seq
MIRT1347650	hsa-miR-4303	CLIP-seq
MIRT2102948	hsa-miR-4318	CLIP-seq
MIRT1347653	hsa-miR-4324	CLIP-seq
MIRT1347654	hsa-miR-4419b	CLIP-seq
MIRT1347655	hsa-miR-4430	CLIP-seq
MIRT2102949	hsa-miR-4451	CLIP-seq
MIRT2102950	hsa-miR-4457	CLIP-seq
MIRT2102951	hsa-miR-4477b	CLIP-seq
MIRT1347657	hsa-miR-4478	CLIP-seq
MIRT2102952	hsa-miR-4490	CLIP-seq
MIRT2102953	hsa-miR-4511	CLIP-seq
MIRT1347660	hsa-miR-451b	CLIP-seq
MIRT1347661	hsa-miR-454	CLIP-seq
MIRT1347662	hsa-miR-4634	CLIP-seq
MIRT1347663	hsa-miR-4649-3p	CLIP-seq
MIRT2102954	hsa-miR-4650-3p	CLIP-seq
MIRT1347664	hsa-miR-4663	CLIP-seq
MIRT2102955	hsa-miR-4667-3p	CLIP-seq
MIRT1347665	hsa-miR-4685-5p	CLIP-seq
MIRT2102956	hsa-miR-4693-5p	CLIP-seq
MIRT2102957	hsa-miR-4695-3p	CLIP-seq
MIRT2102958	hsa-miR-4708-3p	CLIP-seq
MIRT2102959	hsa-miR-4733-3p	CLIP-seq
MIRT2102960	hsa-miR-4753-3p	CLIP-seq
MIRT1347671	hsa-miR-4764-5p	CLIP-seq
MIRT2102961	hsa-miR-4773	CLIP-seq
MIRT2102962	hsa-miR-4774-5p	CLIP-seq
MIRT2102963	hsa-miR-4786-3p	CLIP-seq
MIRT1347672	hsa-miR-485-5p	CLIP-seq
MIRT2102964	hsa-miR-506	CLIP-seq
MIRT1347674	hsa-miR-544	CLIP-seq
MIRT1347675	hsa-miR-544b	CLIP-seq
MIRT2102965	hsa-miR-596	CLIP-seq
MIRT2102966	hsa-miR-603	CLIP-seq
MIRT2102967	hsa-miR-628-5p	CLIP-seq
MIRT2102968	hsa-miR-634	CLIP-seq
MIRT1347677	hsa-miR-652	CLIP-seq
MIRT1347679	hsa-miR-665	CLIP-seq
MIRT2102969	hsa-miR-671-5p	CLIP-seq
MIRT2102970	hsa-miR-767-3p	CLIP-seq
MIRT1347680	hsa-miR-887	CLIP-seq
MIRT2102971	hsa-miR-892a	CLIP-seq
MIRT2102972	hsa-miR-922	CLIP-seq
MIRT2102973	hsa-miR-92a	CLIP-seq
MIRT2102974	hsa-miR-92b	CLIP-seq
MIRT1347612	hsa-miR-103a	CLIP-seq
MIRT1347613	hsa-miR-107	CLIP-seq
MIRT1347614	hsa-miR-1200	CLIP-seq
MIRT1347615	hsa-miR-122	CLIP-seq
MIRT1347616	hsa-miR-1234	CLIP-seq
MIRT2102924	hsa-miR-124	CLIP-seq
MIRT1347617	hsa-miR-1254	CLIP-seq
MIRT2102928	hsa-miR-1260	CLIP-seq
MIRT2102929	hsa-miR-1260b	CLIP-seq
MIRT2327250	hsa-miR-1261	CLIP-seq
MIRT2327251	hsa-miR-1282	CLIP-seq
MIRT2327252	hsa-miR-1297	CLIP-seq
MIRT1347618	hsa-miR-130a	CLIP-seq
MIRT1347619	hsa-miR-130b	CLIP-seq
MIRT2102931	hsa-miR-188-3p	CLIP-seq
MIRT1347623	hsa-miR-1908	CLIP-seq
MIRT2327253	hsa-miR-1910	CLIP-seq
MIRT1347624	hsa-miR-1911	CLIP-seq
MIRT1347625	hsa-miR-1976	CLIP-seq
MIRT2327254	hsa-miR-2053	CLIP-seq
MIRT1347626	hsa-miR-2110	CLIP-seq
MIRT1347627	hsa-miR-2467-5p	CLIP-seq
MIRT2102932	hsa-miR-25	CLIP-seq
MIRT2327255	hsa-miR-26a	CLIP-seq
MIRT2327256	hsa-miR-26b	CLIP-seq
MIRT2327257	hsa-miR-27a	CLIP-seq
MIRT2327258	hsa-miR-27b	CLIP-seq
MIRT1347628	hsa-miR-301a	CLIP-seq
MIRT1347629	hsa-miR-301b	CLIP-seq
MIRT2102933	hsa-miR-3074-5p	CLIP-seq
MIRT1347630	hsa-miR-3116	CLIP-seq
MIRT2327259	hsa-miR-3126-3p	CLIP-seq
MIRT1347632	hsa-miR-3135b	CLIP-seq
MIRT2327260	hsa-miR-3138	CLIP-seq
MIRT2102936	hsa-miR-3156-3p	CLIP-seq
MIRT2102937	hsa-miR-3162-3p	CLIP-seq
MIRT1347636	hsa-miR-3182	CLIP-seq
MIRT1347637	hsa-miR-3188	CLIP-seq
MIRT1347638	hsa-miR-3194-3p	CLIP-seq
MIRT2102938	hsa-miR-32	CLIP-seq
MIRT1347639	hsa-miR-324-5p	CLIP-seq
MIRT2327261	hsa-miR-338-3p	CLIP-seq
MIRT2327262	hsa-miR-34c-3p	CLIP-seq
MIRT2327263	hsa-miR-3605-5p	CLIP-seq
MIRT2102941	hsa-miR-363	CLIP-seq
MIRT2102942	hsa-miR-3650	CLIP-seq
MIRT1347641	hsa-miR-3652	CLIP-seq
MIRT1347642	hsa-miR-3666	CLIP-seq
MIRT2102943	hsa-miR-367	CLIP-seq
MIRT1347643	hsa-miR-3690	CLIP-seq
MIRT1347644	hsa-miR-3929	CLIP-seq
MIRT2327264	hsa-miR-3936	CLIP-seq
MIRT1347646	hsa-miR-3975	CLIP-seq
MIRT1347647	hsa-miR-4271	CLIP-seq
MIRT2327265	hsa-miR-4274	CLIP-seq
MIRT2327266	hsa-miR-4282	CLIP-seq
MIRT1347649	hsa-miR-4295	CLIP-seq
MIRT1347650	hsa-miR-4303	CLIP-seq
MIRT2102948	hsa-miR-4318	CLIP-seq
MIRT1347653	hsa-miR-4324	CLIP-seq
MIRT1347654	hsa-miR-4419b	CLIP-seq
MIRT1347655	hsa-miR-4430	CLIP-seq
MIRT2327267	hsa-miR-4438	CLIP-seq
MIRT2327268	hsa-miR-4465	CLIP-seq
MIRT1347657	hsa-miR-4478	CLIP-seq
MIRT1347658	hsa-miR-4493	CLIP-seq
MIRT2327269	hsa-miR-450b-3p	CLIP-seq
MIRT2102953	hsa-miR-4511	CLIP-seq
MIRT1347660	hsa-miR-451b	CLIP-seq
MIRT1347661	hsa-miR-454	CLIP-seq
MIRT2327270	hsa-miR-455-3p	CLIP-seq
MIRT1347662	hsa-miR-4634	CLIP-seq
MIRT1347663	hsa-miR-4649-3p	CLIP-seq
MIRT2327271	hsa-miR-4652-5p	CLIP-seq
MIRT1347664	hsa-miR-4663	CLIP-seq
MIRT2102956	hsa-miR-4693-5p	CLIP-seq
MIRT2102957	hsa-miR-4695-3p	CLIP-seq
MIRT1347667	hsa-miR-4706	CLIP-seq
MIRT2327272	hsa-miR-4713-3p	CLIP-seq
MIRT2327273	hsa-miR-4713-5p	CLIP-seq
MIRT2327274	hsa-miR-4722-3p	CLIP-seq
MIRT1347669	hsa-miR-4725-3p	CLIP-seq
MIRT1347670	hsa-miR-4749-5p	CLIP-seq
MIRT1347671	hsa-miR-4764-5p	CLIP-seq
MIRT2327275	hsa-miR-4768-3p	CLIP-seq
MIRT2327276	hsa-miR-4772-3p	CLIP-seq
MIRT2327277	hsa-miR-4787-3p	CLIP-seq
MIRT2327278	hsa-miR-4800-5p	CLIP-seq
MIRT1347672	hsa-miR-485-5p	CLIP-seq
MIRT1347673	hsa-miR-491-5p	CLIP-seq
MIRT2102964	hsa-miR-506	CLIP-seq
MIRT2327279	hsa-miR-5095	CLIP-seq
MIRT2327280	hsa-miR-513a-5p	CLIP-seq
MIRT1347674	hsa-miR-544	CLIP-seq
MIRT1347675	hsa-miR-544b	CLIP-seq
MIRT2327281	hsa-miR-569	CLIP-seq
MIRT2327282	hsa-miR-579	CLIP-seq
MIRT2102965	hsa-miR-596	CLIP-seq
MIRT2102968	hsa-miR-634	CLIP-seq
MIRT2327283	hsa-miR-638	CLIP-seq
MIRT1347677	hsa-miR-652	CLIP-seq
MIRT1347678	hsa-miR-663	CLIP-seq
MIRT1347679	hsa-miR-665	CLIP-seq
MIRT2327284	hsa-miR-769-3p	CLIP-seq
MIRT2102971	hsa-miR-892a	CLIP-seq
MIRT2102972	hsa-miR-922	CLIP-seq
MIRT2102973	hsa-miR-92a	CLIP-seq
MIRT2102974	hsa-miR-92b	CLIP-seq
MIRT1347682	hsa-miR-939	CLIP-seq
MIRT1347616	hsa-miR-1234	CLIP-seq
MIRT1347617	hsa-miR-1254	CLIP-seq
MIRT2327250	hsa-miR-1261	CLIP-seq
MIRT1347623	hsa-miR-1908	CLIP-seq
MIRT1347626	hsa-miR-2110	CLIP-seq
MIRT1347630	hsa-miR-3116	CLIP-seq
MIRT1347636	hsa-miR-3182	CLIP-seq
MIRT1347638	hsa-miR-3194-3p	CLIP-seq
MIRT1347643	hsa-miR-3690	CLIP-seq
MIRT2327264	hsa-miR-3936	CLIP-seq
MIRT1347647	hsa-miR-4271	CLIP-seq
MIRT1347650	hsa-miR-4303	CLIP-seq
MIRT2102948	hsa-miR-4318	CLIP-seq
MIRT2327271	hsa-miR-4652-5p	CLIP-seq
MIRT1347664	hsa-miR-4663	CLIP-seq
MIRT2102956	hsa-miR-4693-5p	CLIP-seq
MIRT1347666	hsa-miR-4694-3p	CLIP-seq
MIRT1347667	hsa-miR-4706	CLIP-seq
MIRT1347669	hsa-miR-4725-3p	CLIP-seq
MIRT1347670	hsa-miR-4749-5p	CLIP-seq
MIRT1347671	hsa-miR-4764-5p	CLIP-seq
MIRT1347673	hsa-miR-491-5p	CLIP-seq
MIRT1347674	hsa-miR-544	CLIP-seq
MIRT1347678	hsa-miR-663	CLIP-seq
MIRT1347679	hsa-miR-665	CLIP-seq
MIRT2102971	hsa-miR-892a	CLIP-seq
MIRT1347682	hsa-miR-939	CLIP-seq
MIRT1347615	hsa-miR-122	CLIP-seq
MIRT1347618	hsa-miR-130a	CLIP-seq
MIRT1347619	hsa-miR-130b	CLIP-seq
MIRT1347628	hsa-miR-301a	CLIP-seq
MIRT1347629	hsa-miR-301b	CLIP-seq
MIRT1347632	hsa-miR-3135b	CLIP-seq
MIRT2102937	hsa-miR-3162-3p	CLIP-seq
MIRT1347641	hsa-miR-3652	CLIP-seq
MIRT1347642	hsa-miR-3666	CLIP-seq
MIRT1347649	hsa-miR-4295	CLIP-seq
MIRT1347655	hsa-miR-4430	CLIP-seq
MIRT1347661	hsa-miR-454	CLIP-seq
MIRT1347662	hsa-miR-4634	CLIP-seq
MIRT2102957	hsa-miR-4695-3p	CLIP-seq
MIRT2459332	hsa-miR-4740-3p	CLIP-seq
MIRT2327276	hsa-miR-4772-3p	CLIP-seq
MIRT1347677	hsa-miR-652	CLIP-seq
MIRT2459333	hsa-miR-888	CLIP-seq
MIRT1347614	hsa-miR-1200	CLIP-seq
MIRT1347615	hsa-miR-122	CLIP-seq
MIRT2327250	hsa-miR-1261	CLIP-seq
MIRT2327252	hsa-miR-1297	CLIP-seq
MIRT2622568	hsa-miR-1299	CLIP-seq
MIRT1347618	hsa-miR-130a	CLIP-seq
MIRT1347619	hsa-miR-130b	CLIP-seq
MIRT2327255	hsa-miR-26a	CLIP-seq
MIRT2327256	hsa-miR-26b	CLIP-seq
MIRT1347628	hsa-miR-301a	CLIP-seq
MIRT1347629	hsa-miR-301b	CLIP-seq
MIRT2102933	hsa-miR-3074-5p	CLIP-seq
MIRT1347632	hsa-miR-3135b	CLIP-seq
MIRT2622569	hsa-miR-3149	CLIP-seq
MIRT1347641	hsa-miR-3652	CLIP-seq
MIRT1347642	hsa-miR-3666	CLIP-seq
MIRT2327264	hsa-miR-3936	CLIP-seq
MIRT1347649	hsa-miR-4295	CLIP-seq
MIRT1347653	hsa-miR-4324	CLIP-seq
MIRT1347655	hsa-miR-4430	CLIP-seq
MIRT2327268	hsa-miR-4465	CLIP-seq
MIRT2622570	hsa-miR-4522	CLIP-seq
MIRT1347661	hsa-miR-454	CLIP-seq
MIRT1347662	hsa-miR-4634	CLIP-seq
MIRT2327271	hsa-miR-4652-5p	CLIP-seq
MIRT2102957	hsa-miR-4695-3p	CLIP-seq
MIRT2327274	hsa-miR-4722-3p	CLIP-seq
MIRT2459332	hsa-miR-4740-3p	CLIP-seq
MIRT2327276	hsa-miR-4772-3p	CLIP-seq
MIRT1347675	hsa-miR-544b	CLIP-seq
MIRT1347677	hsa-miR-652	CLIP-seq
MIRT2622571	hsa-miR-7	CLIP-seq
MIRT2622572	hsa-miR-875-3p	CLIP-seq
MIRT1347614	hsa-miR-1200	CLIP-seq
MIRT1347615	hsa-miR-122	CLIP-seq
MIRT2690726	hsa-miR-1245	CLIP-seq
MIRT2327252	hsa-miR-1297	CLIP-seq
MIRT2622568	hsa-miR-1299	CLIP-seq
MIRT1347618	hsa-miR-130a	CLIP-seq
MIRT1347619	hsa-miR-130b	CLIP-seq
MIRT2327255	hsa-miR-26a	CLIP-seq
MIRT2327256	hsa-miR-26b	CLIP-seq
MIRT1347628	hsa-miR-301a	CLIP-seq
MIRT1347629	hsa-miR-301b	CLIP-seq
MIRT2102933	hsa-miR-3074-5p	CLIP-seq
MIRT1347632	hsa-miR-3135b	CLIP-seq
MIRT2622569	hsa-miR-3149	CLIP-seq
MIRT2690727	hsa-miR-3187-3p	CLIP-seq
MIRT1347641	hsa-miR-3652	CLIP-seq
MIRT1347642	hsa-miR-3666	CLIP-seq
MIRT2690728	hsa-miR-383	CLIP-seq
MIRT2690729	hsa-miR-4269	CLIP-seq
MIRT1347649	hsa-miR-4295	CLIP-seq
MIRT1347653	hsa-miR-4324	CLIP-seq
MIRT1347655	hsa-miR-4430	CLIP-seq
MIRT2690730	hsa-miR-4435	CLIP-seq
MIRT2327267	hsa-miR-4438	CLIP-seq
MIRT2327268	hsa-miR-4465	CLIP-seq
MIRT2690731	hsa-miR-4514	CLIP-seq
MIRT2622570	hsa-miR-4522	CLIP-seq
MIRT1347661	hsa-miR-454	CLIP-seq
MIRT1347662	hsa-miR-4634	CLIP-seq
MIRT2690732	hsa-miR-4692	CLIP-seq
MIRT2102957	hsa-miR-4695-3p	CLIP-seq
MIRT2690733	hsa-miR-4701-5p	CLIP-seq
MIRT2327274	hsa-miR-4722-3p	CLIP-seq
MIRT2459332	hsa-miR-4740-3p	CLIP-seq
MIRT2690734	hsa-miR-4742-5p	CLIP-seq
MIRT2690735	hsa-miR-4765	CLIP-seq
MIRT2327276	hsa-miR-4772-3p	CLIP-seq
MIRT2690736	hsa-miR-4772-5p	CLIP-seq
MIRT2327279	hsa-miR-5095	CLIP-seq
MIRT1347675	hsa-miR-544b	CLIP-seq
MIRT2690737	hsa-miR-548s	CLIP-seq
MIRT2690738	hsa-miR-588	CLIP-seq
MIRT1347677	hsa-miR-652	CLIP-seq
MIRT2622571	hsa-miR-7	CLIP-seq
MIRT2690739	hsa-miR-759	CLIP-seq
MIRT2622572	hsa-miR-875-3p	CLIP-seq

Show/Hide all(34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	TAS
GO:0005975	Process	Carbohydrate metabolic process	IDA	19413330
GO:0005975	Process	Carbohydrate metabolic process	IEA
GO:0005975	Process	Carbohydrate metabolic process	TAS	10673275
GO:0006098	Process	Pentose-phosphate shunt	IEA
GO:0006098	Process	Pentose-phosphate shunt	TAS
GO:0009052	Process	Pentose-phosphate shunt, non-oxidative branch	IBA
GO:0009052	Process	Pentose-phosphate shunt, non-oxidative branch	IEA
GO:0009052	Process	Pentose-phosphate shunt, non-oxidative branch	ISS
GO:0016301	Function	Kinase activity	IEA
GO:0016310	Process	Phosphorylation	IDA	19413330
GO:0016740	Function	Transferase activity	IEA
GO:0035963	Process	Cellular response to interleukin-13	IEA
GO:0035963	Process	Cellular response to interleukin-13	ISS
GO:0043030	Process	Regulation of macrophage activation	IBA
GO:0043030	Process	Regulation of macrophage activation	IEA
GO:0043030	Process	Regulation of macrophage activation	ISS
GO:0050277	Function	Sedoheptulokinase activity	IBA
GO:0050277	Function	Sedoheptulokinase activity	IDA	19413330
GO:0050277	Function	Sedoheptulokinase activity	IEA
GO:0050277	Function	Sedoheptulokinase activity	TAS
GO:0050727	Process	Regulation of inflammatory response	IEA
GO:0050727	Process	Regulation of inflammatory response	ISS
GO:0071222	Process	Cellular response to lipopolysaccharide	IBA
GO:0071222	Process	Cellular response to lipopolysaccharide	IDA	22682222
GO:0071222	Process	Cellular response to lipopolysaccharide	IEA
GO:0071353	Process	Cellular response to interleukin-4	IEA
GO:0071353	Process	Cellular response to interleukin-4	ISS

MIM	HGNC	e!Ensembl
605060	1492	ENSG00000197417

Protein

UniProt ID

Q9UHJ6

Protein name

Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein)

Protein function

Acts as a modulator of macrophage activation through control of glucose metabolism.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00370	FGGY_N	6 → 265	FGGY family of carbohydrate kinases, N-terminal domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain. {ECO:0000269|PubMed:10673275}.

Sequence

MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQ
DVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRA
VSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHD
YVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRT
SHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDP
TAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQ
QRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQ
DWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES

Sequence length

478

Interactions

View interactions

	KEGG		Reactome
	Pentose phosphate pathway Metabolic pathways		Pentose phosphate pathway

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Dementia	Dementia	N/A	N/A	GWAS
Isolated Sedoheptulokinase Deficiency	isolated sedoheptulokinase deficiency	N/A	N/A	ClinVar, GenCC

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Cystinosis	Associate	11505338
Diabetes Mellitus Type 1	Associate	17984097
Glioblastoma	Stimulate	35682658
Multiple Sclerosis	Inhibit	17984097
Neoplasms	Associate	35682658

SHPK (sedoheptulokinase)