SGK3 (serum/glucocorticoid regulated kinase family member 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23678 |
| Gene name | Serum/glucocorticoid regulated kinase family member 3 |
| Gene symbol | SGK3 |
| Synonyms (NCBI Gene) |
CISKSGK2SGKL
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| Chromosome | 8 |
| Chromosome location | 8q13.1 |
| Summary | This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chl |
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miRNA
miRNA information provided by mirtarbase database.
365
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96BR1 | ||||||||||||||||||||
| Protein name | Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) | ||||||||||||||||||||
| Protein function | Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: | ||||||||||||||||||||
| PDB | 6EDX | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle. Expression is higher in ER-positive breast tumors than ER-negative breast tumors. {ECO:000 | ||||||||||||||||||||
| Sequence |
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| Sequence length | 496 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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