ZKSCAN5 (zinc finger with KRAB and SCAN domains 5)

Gene

• Entrez ID: 23660
• Gene name: Zinc finger with KRAB and SCAN domains 5
• Gene symbol: ZKSCAN5
• Synonyms (NCBI Gene): ZFP-95, ZFP95, ZNF914, ZSCAN37
• Chromosome: 7
• Chromosome location: 7q22.1
• Summary: This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB A domain and may be involved in transcriptional regulation. A similar protein in mouse is differentially expressed in spermatogenesis. Alternative sp

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021052	hsa-miR-155-5p	Proteomics;Other	20584899
MIRT223217	hsa-miR-382-5p	PAR-CLIP	22100165
MIRT223220	hsa-miR-875-3p	PAR-CLIP	22100165
MIRT223224	hsa-miR-4635	PAR-CLIP	22100165
MIRT445128	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT223221	hsa-miR-3148	PAR-CLIP	22100165
MIRT445127	hsa-miR-6124	PAR-CLIP	22100165
MIRT223222	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT223219	hsa-miR-573	PAR-CLIP	22100165
MIRT223223	hsa-miR-1273e	PAR-CLIP	22100165
MIRT223217	hsa-miR-382-5p	PAR-CLIP	22100165
MIRT223220	hsa-miR-875-3p	PAR-CLIP	22100165
MIRT223224	hsa-miR-4635	PAR-CLIP	22100165
MIRT445128	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT223221	hsa-miR-3148	PAR-CLIP	22100165
MIRT445127	hsa-miR-6124	PAR-CLIP	22100165
MIRT223222	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT223219	hsa-miR-573	PAR-CLIP	22100165
MIRT223223	hsa-miR-1273e	PAR-CLIP	22100165
MIRT021052	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT021052	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT223217	hsa-miR-382-5p	PAR-CLIP	22100165
MIRT223220	hsa-miR-875-3p	PAR-CLIP	22100165
MIRT223224	hsa-miR-4635	PAR-CLIP	22100165
MIRT445128	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT223221	hsa-miR-3148	PAR-CLIP	22100165
MIRT445127	hsa-miR-6124	PAR-CLIP	22100165
MIRT223222	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT223219	hsa-miR-573	PAR-CLIP	22100165
MIRT223223	hsa-miR-1273e	PAR-CLIP	22100165
MIRT223217	hsa-miR-382-5p	PAR-CLIP	22100165
MIRT223220	hsa-miR-875-3p	PAR-CLIP	22100165
MIRT223224	hsa-miR-4635	PAR-CLIP	22100165
MIRT445128	hsa-miR-4670-3p	PAR-CLIP	22100165
MIRT223221	hsa-miR-3148	PAR-CLIP	22100165
MIRT445127	hsa-miR-6124	PAR-CLIP	22100165
MIRT223222	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT223219	hsa-miR-573	PAR-CLIP	22100165
MIRT223223	hsa-miR-1273e	PAR-CLIP	22100165
MIRT1514030	hsa-miR-1207-3p	CLIP-seq
MIRT1514031	hsa-miR-1304	CLIP-seq
MIRT1514032	hsa-miR-1321	CLIP-seq
MIRT1514033	hsa-miR-2278	CLIP-seq
MIRT1514034	hsa-miR-3126-5p	CLIP-seq
MIRT1514035	hsa-miR-4419a	CLIP-seq
MIRT1514036	hsa-miR-4421	CLIP-seq
MIRT1514037	hsa-miR-4450	CLIP-seq
MIRT1514038	hsa-miR-4510	CLIP-seq
MIRT1514039	hsa-miR-4667-5p	CLIP-seq
MIRT1514040	hsa-miR-4700-5p	CLIP-seq
MIRT1514041	hsa-miR-4728-5p	CLIP-seq
MIRT1514042	hsa-miR-4731-5p	CLIP-seq
MIRT1514043	hsa-miR-4739	CLIP-seq
MIRT1514044	hsa-miR-4756-5p	CLIP-seq
MIRT1514045	hsa-miR-494	CLIP-seq
MIRT1514046	hsa-miR-646	CLIP-seq
MIRT1514047	hsa-miR-767-3p	CLIP-seq
MIRT1514048	hsa-miR-942	CLIP-seq
MIRT1514049	hsa-miR-125a-5p	CLIP-seq
MIRT1514050	hsa-miR-125b	CLIP-seq
MIRT1514031	hsa-miR-1304	CLIP-seq
MIRT1514032	hsa-miR-1321	CLIP-seq
MIRT1514051	hsa-miR-155	CLIP-seq
MIRT1514052	hsa-miR-1976	CLIP-seq
MIRT1514053	hsa-miR-219-2-3p	CLIP-seq
MIRT1514054	hsa-miR-2964a-3p	CLIP-seq
MIRT1514034	hsa-miR-3126-5p	CLIP-seq
MIRT1514055	hsa-miR-3140-5p	CLIP-seq
MIRT1514056	hsa-miR-3714	CLIP-seq
MIRT1514057	hsa-miR-3973	CLIP-seq
MIRT1514058	hsa-miR-4279	CLIP-seq
MIRT1514059	hsa-miR-4318	CLIP-seq
MIRT1514060	hsa-miR-4319	CLIP-seq
MIRT1514035	hsa-miR-4419a	CLIP-seq
MIRT1514061	hsa-miR-4427	CLIP-seq
MIRT1514038	hsa-miR-4510	CLIP-seq
MIRT1514062	hsa-miR-4521	CLIP-seq
MIRT1514063	hsa-miR-4639-5p	CLIP-seq
MIRT1514064	hsa-miR-4680-3p	CLIP-seq
MIRT1514065	hsa-miR-4693-5p	CLIP-seq
MIRT1514066	hsa-miR-4712-5p	CLIP-seq
MIRT1514041	hsa-miR-4728-5p	CLIP-seq
MIRT1514067	hsa-miR-4732-3p	CLIP-seq
MIRT1514043	hsa-miR-4739	CLIP-seq
MIRT1514044	hsa-miR-4756-5p	CLIP-seq
MIRT1514068	hsa-miR-4796-3p	CLIP-seq
MIRT1514045	hsa-miR-494	CLIP-seq
MIRT1514069	hsa-miR-520g	CLIP-seq
MIRT1514070	hsa-miR-520h	CLIP-seq
MIRT1514071	hsa-miR-569	CLIP-seq
MIRT1514072	hsa-miR-582-5p	CLIP-seq
MIRT1514073	hsa-miR-670	CLIP-seq
MIRT1514074	hsa-miR-770-5p	CLIP-seq
MIRT1514075	hsa-miR-892a	CLIP-seq
MIRT1514076	hsa-miR-933	CLIP-seq
MIRT1514055	hsa-miR-3140-5p	CLIP-seq
MIRT2155058	hsa-miR-4699-5p	CLIP-seq
MIRT2155059	hsa-miR-4777-5p	CLIP-seq
MIRT2463996	hsa-miR-24	CLIP-seq
MIRT2463997	hsa-miR-3155	CLIP-seq
MIRT2463998	hsa-miR-3155b	CLIP-seq
MIRT2463999	hsa-miR-4287	CLIP-seq
MIRT2464000	hsa-miR-4438	CLIP-seq
MIRT2464001	hsa-miR-4469	CLIP-seq
MIRT2464002	hsa-miR-4639-3p	CLIP-seq
MIRT2464003	hsa-miR-4685-3p	CLIP-seq
MIRT2464004	hsa-miR-484	CLIP-seq
MIRT2464005	hsa-miR-548p	CLIP-seq
MIRT2463996	hsa-miR-24	CLIP-seq
MIRT2463997	hsa-miR-3155	CLIP-seq
MIRT2463998	hsa-miR-3155b	CLIP-seq
MIRT2463999	hsa-miR-4287	CLIP-seq
MIRT2464000	hsa-miR-4438	CLIP-seq
MIRT2464001	hsa-miR-4469	CLIP-seq
MIRT2464002	hsa-miR-4639-3p	CLIP-seq
MIRT2464003	hsa-miR-4685-3p	CLIP-seq
MIRT2464004	hsa-miR-484	CLIP-seq
MIRT2464005	hsa-miR-548p	CLIP-seq
MIRT1514055	hsa-miR-3140-5p	CLIP-seq
MIRT1514056	hsa-miR-3714	CLIP-seq
MIRT1514067	hsa-miR-4732-3p	CLIP-seq
MIRT2667444	hsa-miR-1237	CLIP-seq
MIRT2667445	hsa-miR-124	CLIP-seq
MIRT2667446	hsa-miR-1248	CLIP-seq
MIRT1514049	hsa-miR-125a-5p	CLIP-seq
MIRT1514050	hsa-miR-125b	CLIP-seq
MIRT2667447	hsa-miR-133a	CLIP-seq
MIRT2667448	hsa-miR-133b	CLIP-seq
MIRT2667449	hsa-miR-139-5p	CLIP-seq
MIRT2667450	hsa-miR-1912	CLIP-seq
MIRT2667451	hsa-miR-197	CLIP-seq
MIRT1514052	hsa-miR-1976	CLIP-seq
MIRT2667452	hsa-miR-199a-3p	CLIP-seq
MIRT2667453	hsa-miR-199b-3p	CLIP-seq
MIRT1514053	hsa-miR-219-2-3p	CLIP-seq
MIRT2667454	hsa-miR-27a	CLIP-seq
MIRT2667455	hsa-miR-27b	CLIP-seq
MIRT1514054	hsa-miR-2964a-3p	CLIP-seq
MIRT2667456	hsa-miR-3065-3p	CLIP-seq
MIRT2667457	hsa-miR-3074-3p	CLIP-seq
MIRT2667458	hsa-miR-3129-5p	CLIP-seq
MIRT1514055	hsa-miR-3140-5p	CLIP-seq
MIRT2667459	hsa-miR-3165	CLIP-seq
MIRT2667460	hsa-miR-3649	CLIP-seq
MIRT2667461	hsa-miR-3659	CLIP-seq
MIRT2667462	hsa-miR-3686	CLIP-seq
MIRT1514056	hsa-miR-3714	CLIP-seq
MIRT2667463	hsa-miR-3910	CLIP-seq
MIRT2667464	hsa-miR-3913-3p	CLIP-seq
MIRT2667465	hsa-miR-3919	CLIP-seq
MIRT2667466	hsa-miR-3927	CLIP-seq
MIRT1514058	hsa-miR-4279	CLIP-seq
MIRT2667467	hsa-miR-4314	CLIP-seq
MIRT1514059	hsa-miR-4318	CLIP-seq
MIRT1514060	hsa-miR-4319	CLIP-seq
MIRT1514061	hsa-miR-4427	CLIP-seq
MIRT2667468	hsa-miR-4451	CLIP-seq
MIRT1514062	hsa-miR-4521	CLIP-seq
MIRT2667469	hsa-miR-4539	CLIP-seq
MIRT1514063	hsa-miR-4639-5p	CLIP-seq
MIRT1514039	hsa-miR-4667-5p	CLIP-seq
MIRT1514064	hsa-miR-4680-3p	CLIP-seq
MIRT1514065	hsa-miR-4693-5p	CLIP-seq
MIRT2667470	hsa-miR-4700-3p	CLIP-seq
MIRT1514040	hsa-miR-4700-5p	CLIP-seq
MIRT1514066	hsa-miR-4712-5p	CLIP-seq
MIRT2667471	hsa-miR-4724-5p	CLIP-seq
MIRT1514042	hsa-miR-4731-5p	CLIP-seq
MIRT1514067	hsa-miR-4732-3p	CLIP-seq
MIRT2667472	hsa-miR-4738-3p	CLIP-seq
MIRT2667473	hsa-miR-4742-3p	CLIP-seq
MIRT2667474	hsa-miR-4768-3p	CLIP-seq
MIRT2667475	hsa-miR-4778-5p	CLIP-seq
MIRT2667476	hsa-miR-4789-3p	CLIP-seq
MIRT2667477	hsa-miR-4795-5p	CLIP-seq
MIRT2667478	hsa-miR-486-3p	CLIP-seq
MIRT2667479	hsa-miR-489	CLIP-seq
MIRT2667480	hsa-miR-506	CLIP-seq
MIRT2667481	hsa-miR-513a-5p	CLIP-seq
MIRT1514072	hsa-miR-582-5p	CLIP-seq
MIRT2667482	hsa-miR-606	CLIP-seq
MIRT2667483	hsa-miR-624	CLIP-seq
MIRT2667484	hsa-miR-637	CLIP-seq
MIRT1514073	hsa-miR-670	CLIP-seq
MIRT1514074	hsa-miR-770-5p	CLIP-seq
MIRT1514075	hsa-miR-892a	CLIP-seq
MIRT2667485	hsa-miR-922	CLIP-seq
MIRT1514076	hsa-miR-933	CLIP-seq
MIRT2667486	hsa-miR-936	CLIP-seq
MIRT1514055	hsa-miR-3140-5p	CLIP-seq
MIRT1514056	hsa-miR-3714	CLIP-seq
MIRT1514067	hsa-miR-4732-3p	CLIP-seq
MIRT2667444	hsa-miR-1237	CLIP-seq
MIRT2667446	hsa-miR-1248	CLIP-seq
MIRT2667449	hsa-miR-139-5p	CLIP-seq
MIRT2667450	hsa-miR-1912	CLIP-seq
MIRT2667451	hsa-miR-197	CLIP-seq
MIRT1514052	hsa-miR-1976	CLIP-seq
MIRT2667452	hsa-miR-199a-3p	CLIP-seq
MIRT2667453	hsa-miR-199b-3p	CLIP-seq
MIRT1514053	hsa-miR-219-2-3p	CLIP-seq
MIRT2463996	hsa-miR-24	CLIP-seq
MIRT2667454	hsa-miR-27a	CLIP-seq
MIRT2667455	hsa-miR-27b	CLIP-seq
MIRT1514054	hsa-miR-2964a-3p	CLIP-seq
MIRT2667456	hsa-miR-3065-3p	CLIP-seq
MIRT2667457	hsa-miR-3074-3p	CLIP-seq
MIRT2667458	hsa-miR-3129-5p	CLIP-seq
MIRT1514055	hsa-miR-3140-5p	CLIP-seq
MIRT2463997	hsa-miR-3155	CLIP-seq
MIRT2463998	hsa-miR-3155b	CLIP-seq
MIRT2667460	hsa-miR-3649	CLIP-seq
MIRT2667461	hsa-miR-3659	CLIP-seq
MIRT2667462	hsa-miR-3686	CLIP-seq
MIRT2667464	hsa-miR-3913-3p	CLIP-seq
MIRT2667466	hsa-miR-3927	CLIP-seq
MIRT1514058	hsa-miR-4279	CLIP-seq
MIRT2463999	hsa-miR-4287	CLIP-seq
MIRT2667467	hsa-miR-4314	CLIP-seq
MIRT2464000	hsa-miR-4438	CLIP-seq
MIRT2667468	hsa-miR-4451	CLIP-seq
MIRT2464001	hsa-miR-4469	CLIP-seq
MIRT2667469	hsa-miR-4539	CLIP-seq
MIRT2464002	hsa-miR-4639-3p	CLIP-seq
MIRT1514039	hsa-miR-4667-5p	CLIP-seq
MIRT1514064	hsa-miR-4680-3p	CLIP-seq
MIRT2464003	hsa-miR-4685-3p	CLIP-seq
MIRT2667470	hsa-miR-4700-3p	CLIP-seq
MIRT1514040	hsa-miR-4700-5p	CLIP-seq
MIRT1514066	hsa-miR-4712-5p	CLIP-seq
MIRT2667471	hsa-miR-4724-5p	CLIP-seq
MIRT1514042	hsa-miR-4731-5p	CLIP-seq
MIRT1514067	hsa-miR-4732-3p	CLIP-seq
MIRT2667472	hsa-miR-4738-3p	CLIP-seq
MIRT2667473	hsa-miR-4742-3p	CLIP-seq
MIRT2667474	hsa-miR-4768-3p	CLIP-seq
MIRT2667475	hsa-miR-4778-5p	CLIP-seq
MIRT2667476	hsa-miR-4789-3p	CLIP-seq
MIRT2464004	hsa-miR-484	CLIP-seq
MIRT2667478	hsa-miR-486-3p	CLIP-seq
MIRT2667479	hsa-miR-489	CLIP-seq
MIRT2667481	hsa-miR-513a-5p	CLIP-seq
MIRT2464005	hsa-miR-548p	CLIP-seq
MIRT1514072	hsa-miR-582-5p	CLIP-seq
MIRT2667482	hsa-miR-606	CLIP-seq
MIRT2667483	hsa-miR-624	CLIP-seq
MIRT2667484	hsa-miR-637	CLIP-seq
MIRT1514074	hsa-miR-770-5p	CLIP-seq
MIRT2667486	hsa-miR-936	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	NAS	10585779
GO:0005515	Function	Protein binding	IPI	23455924, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	10585779
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	10585779
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	NAS	10585779
GO:0010558	Process	Negative regulation of macromolecule biosynthetic process	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 611272
• HGNC: 12867
• e!Ensembl: ENSG00000196652

Protein

• UniProt ID: Q9Y2L8
• Protein name: Zinc finger protein with KRAB and SCAN domains 5 (Zinc finger protein 95 homolog) (Zfp-95)
• Protein function: May be involved in transcriptional regulation.
• PDB: 2EM5, 2EMM, 2EMZ, 2EN3, 2EOM, 2EON, 2EOO, 2YSO, 2YTG
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02023	SCAN	46 → 135	SCAN domain	Domain
  PF01352	KRAB	220 → 258	KRAB box	Family
  PF00096	zf-C2H2	346 → 368	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	374 → 396	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	402 → 424	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	430 → 452	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	549 → 571	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	577 → 599	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	605 → 627	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	633 → 655	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	717 → 739	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	773 → 795	Zinc finger, C2H2 type	Domain

• Sequence:

  MIMTESREVIDLDPPAETSQEQEDLFIVKVEEEDCTWMQEYNPPTFETFYQRFRHFQYHE
  ASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQPWVREHHPESGEE
  AVAVIENIQRELEERRQQIVACPDVLPRKMATPGAVQESCSPHPLTVDTQPEQAPQKPRL
  LEENALPVLQVPSLPLKDSQELTASLLSTGSQKLVKIEEVADVAVSFILEEWGHLDQSQK
  SLYRDDRKENYGSITSMGYESRDNMELIVKQISDDSESHWVAPEHTERSVPQDPDFAEVS
  DLKGMVQRWQVNPTVGKSRQNPSQKRDLDAITDISPKQSTHGERGHRCSDCGKFFLQASN
  FIQHRRIHTGEKPFKCGECGKSYNQRVHLTQHQRVHTGEKPYKCQVCGKAFRVSSHLVQH
  HSVHSGERPYGCNECGKNFGRHSHLIEHLKRHFREKSQRCSDKRSKNTKLSVKKKISEYS
  EADMELSGKTQRNVSQVQDFGEGCEFQGKLDRKQGIPMKEILGQPSSKRMNYSEVPYVHK
  KSSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRCEECGKSYNQRVHLTQHQRVHT
  GEKPYTCPLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRRSHLAGHLRLHSREKS
  HQCRECGEIFFQYVSLIEHQVLHMGQKNEKNGICEEAYSWNLTVIEDKKIELQEQPYQCD
  ICGKAFGYSSDLIQHYRTHTAEKPYQCDICRENVGQCSHTKQHQKIYSSTKSHQCHECGR
  GFTLKSHLNQHQRIHTGEKPFQCKECGMNFSWSCSLFKHLRSHERTDPINTLSVEGSLL

• Sequence length: 839

Pathways

Reactome:

Generic Transcription Pathway