ZIM2 (zinc finger imprinted 2)

Gene

• Entrez ID: 23619
• Gene name: Zinc finger imprinted 2
• Gene symbol: ZIM2
• Synonyms (NCBI Gene): ZNF656
• Chromosome: 19
• Chromosome location: 19q13.43
• Summary: In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5` exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1513615	hsa-miR-409-3p	CLIP-seq
MIRT1513616	hsa-miR-4266	CLIP-seq
MIRT1513617	hsa-miR-4695-5p	CLIP-seq
MIRT1513618	hsa-miR-4779	CLIP-seq
MIRT1513619	hsa-miR-4786-3p	CLIP-seq
MIRT1513620	hsa-miR-539	CLIP-seq
MIRT1513621	hsa-miR-580	CLIP-seq
MIRT1513622	hsa-miR-671-5p	CLIP-seq
MIRT1513616	hsa-miR-4266	CLIP-seq
MIRT1513617	hsa-miR-4695-5p	CLIP-seq
MIRT1513618	hsa-miR-4779	CLIP-seq
MIRT1513616	hsa-miR-4266	CLIP-seq
MIRT1513617	hsa-miR-4695-5p	CLIP-seq
MIRT1513618	hsa-miR-4779	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	NAS	34673265
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	10708526
GO:0006357	Process	Regulation of transcription by RNA polymerase II	NAS	34673265
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	NAS	10708526
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9NZV7
• Protein name: Zinc finger imprinted 2 (Zinc finger protein 656)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	175 → 216	KRAB box	Family
  PF13894	zf-C2H2_4	328 → 351		Domain
  PF00096	zf-C2H2	466 → 488	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	494 → 516	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highest levels of expression in adult testis; modest levels in fetal kidney and brain.
• Sequence:

  MYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSGDRDWDRRGRSRDMEPRDRWSHTRN
  PRSRMPPRDLSLPVVAKTSFEMDREDDRDSRAYESRSQDAESYQNVVDLAEDRKPHNTIQ
  DNMENYRKLLSLGFLAQDSVPAEKRNTEMLDNLPSAGSQFPDFKHLGTFLVFEELVTFED
  VLVDFSPEELSSLSAAQRNLYREVMLENYRNLVSLGHQFSKPDIISRLEEEESYAMETDS
  RHTVICQGESHDDPLEPHQGNQEKLLTPITMNDPKTLTPERSYGSDEFERSSNLSKQSKD
  PLGKDPQEGTAPGICTSPQSASQENKHNRCEFCKRTFSTQVALRRHERIHTGKKPYECKQ
  CAEAFYLMPHLNRHQKTHSGRKTSGCNEGRKPSVQCANLCERVRIHSQEDYFECFQCGKA
  FLQNVHLLQHLKAHEAARVLPPGLSHSKTYLIRYQRKHDYVGERACQCCDCGRVFSRNSY
  LIQHYRTHTQERPYQCQLCGKCFGRPSYLTQHYQLHSQEKTVECDHC

• Sequence length: 527

Pathways

Reactome:

Generic Transcription Pathway