Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23613
Gene name	Zinc finger MYND-type containing 8
Gene symbol	ZMYND8
Synonyms (NCBI Gene)	PRKCBP1PRO2893RACK7
Chromosome	20
Chromosome location	20q13.12
Summary	The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Fi

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miRTarBase ID	miRNA	Experiments	Reference
MIRT050675	hsa-miR-18a-5p	CLASH	23622248
MIRT049407	hsa-miR-92a-3p	CLASH	23622248
MIRT039404	hsa-miR-421	CLASH	23622248
MIRT037778	hsa-miR-548d-5p	CLASH	23622248
MIRT615847	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT439226	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT439226	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT726062	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT726061	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT726060	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT726059	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT726058	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT615847	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT1515447	hsa-miR-2115	CLIP-seq
MIRT1515448	hsa-miR-3921	CLIP-seq
MIRT1515449	hsa-miR-3977	CLIP-seq
MIRT1515450	hsa-miR-4256	CLIP-seq
MIRT1515451	hsa-miR-4653-5p	CLIP-seq
MIRT1515452	hsa-miR-502-5p	CLIP-seq
MIRT1515453	hsa-miR-516a-3p	CLIP-seq
MIRT1515454	hsa-miR-627	CLIP-seq
MIRT1515455	hsa-miR-1184	CLIP-seq
MIRT1515456	hsa-miR-1205	CLIP-seq
MIRT1515457	hsa-miR-1236	CLIP-seq
MIRT1515458	hsa-miR-1262	CLIP-seq
MIRT1515459	hsa-miR-129-5p	CLIP-seq
MIRT1515460	hsa-miR-132	CLIP-seq
MIRT1515461	hsa-miR-188-5p	CLIP-seq
MIRT1515462	hsa-miR-204	CLIP-seq
MIRT1515463	hsa-miR-211	CLIP-seq
MIRT1515464	hsa-miR-212	CLIP-seq
MIRT1515465	hsa-miR-30a	CLIP-seq
MIRT1515466	hsa-miR-30b	CLIP-seq
MIRT1515467	hsa-miR-30c	CLIP-seq
MIRT1515468	hsa-miR-30d	CLIP-seq
MIRT1515469	hsa-miR-30e	CLIP-seq
MIRT1515470	hsa-miR-3147	CLIP-seq
MIRT1515471	hsa-miR-3151	CLIP-seq
MIRT1515472	hsa-miR-3158-5p	CLIP-seq
MIRT1515473	hsa-miR-3160-3p	CLIP-seq
MIRT1515474	hsa-miR-3170	CLIP-seq
MIRT1515475	hsa-miR-3182	CLIP-seq
MIRT1515476	hsa-miR-323-3p	CLIP-seq
MIRT1515477	hsa-miR-323b-3p	CLIP-seq
MIRT1515478	hsa-miR-330-3p	CLIP-seq
MIRT1515479	hsa-miR-3545-5p	CLIP-seq
MIRT1515480	hsa-miR-3607-3p	CLIP-seq
MIRT1515481	hsa-miR-3659	CLIP-seq
MIRT1515482	hsa-miR-3686	CLIP-seq
MIRT1515483	hsa-miR-374c	CLIP-seq
MIRT1515448	hsa-miR-3921	CLIP-seq
MIRT1515450	hsa-miR-4256	CLIP-seq
MIRT1515484	hsa-miR-4266	CLIP-seq
MIRT1515485	hsa-miR-4280	CLIP-seq
MIRT1515486	hsa-miR-4281	CLIP-seq
MIRT1515487	hsa-miR-4283	CLIP-seq
MIRT1515488	hsa-miR-4425	CLIP-seq
MIRT1515489	hsa-miR-4446-5p	CLIP-seq
MIRT1515490	hsa-miR-4455	CLIP-seq
MIRT1515491	hsa-miR-4481	CLIP-seq
MIRT1515492	hsa-miR-4487	CLIP-seq
MIRT1515493	hsa-miR-4489	CLIP-seq
MIRT1515451	hsa-miR-4653-5p	CLIP-seq
MIRT1515494	hsa-miR-4658	CLIP-seq
MIRT1515495	hsa-miR-4699-3p	CLIP-seq
MIRT1515496	hsa-miR-4701-3p	CLIP-seq
MIRT1515497	hsa-miR-4705	CLIP-seq
MIRT1515498	hsa-miR-4707-5p	CLIP-seq
MIRT1515499	hsa-miR-4717-3p	CLIP-seq
MIRT1515500	hsa-miR-4719	CLIP-seq
MIRT1515501	hsa-miR-4731-5p	CLIP-seq
MIRT1515502	hsa-miR-4745-5p	CLIP-seq
MIRT1515503	hsa-miR-4753-3p	CLIP-seq
MIRT1515504	hsa-miR-4755-5p	CLIP-seq
MIRT1515505	hsa-miR-4758-5p	CLIP-seq
MIRT1515506	hsa-miR-4768-5p	CLIP-seq
MIRT1515507	hsa-miR-4796-3p	CLIP-seq
MIRT1515508	hsa-miR-486-5p	CLIP-seq
MIRT1515509	hsa-miR-496	CLIP-seq
MIRT1515510	hsa-miR-515-5p	CLIP-seq
MIRT1515511	hsa-miR-543	CLIP-seq
MIRT1515512	hsa-miR-558	CLIP-seq
MIRT1515513	hsa-miR-561	CLIP-seq
MIRT1515514	hsa-miR-574-5p	CLIP-seq
MIRT1515515	hsa-miR-591	CLIP-seq
MIRT1515516	hsa-miR-595	CLIP-seq
MIRT1515517	hsa-miR-609	CLIP-seq
MIRT1515518	hsa-miR-622	CLIP-seq
MIRT1515519	hsa-miR-623	CLIP-seq
MIRT1515520	hsa-miR-651	CLIP-seq
MIRT1515521	hsa-miR-655	CLIP-seq
MIRT1515455	hsa-miR-1184	CLIP-seq
MIRT1515456	hsa-miR-1205	CLIP-seq
MIRT2155569	hsa-miR-1206	CLIP-seq
MIRT2155570	hsa-miR-1224-5p	CLIP-seq
MIRT1515457	hsa-miR-1236	CLIP-seq
MIRT2155571	hsa-miR-1249	CLIP-seq
MIRT2155572	hsa-miR-1255a	CLIP-seq
MIRT2155573	hsa-miR-1255b	CLIP-seq
MIRT1515458	hsa-miR-1262	CLIP-seq
MIRT2155574	hsa-miR-1293	CLIP-seq
MIRT1515459	hsa-miR-129-5p	CLIP-seq
MIRT1515460	hsa-miR-132	CLIP-seq
MIRT2155575	hsa-miR-150	CLIP-seq
MIRT1515461	hsa-miR-188-5p	CLIP-seq
MIRT1515447	hsa-miR-2115	CLIP-seq
MIRT1515464	hsa-miR-212	CLIP-seq
MIRT1515465	hsa-miR-30a	CLIP-seq
MIRT1515466	hsa-miR-30b	CLIP-seq
MIRT1515467	hsa-miR-30c	CLIP-seq
MIRT1515468	hsa-miR-30d	CLIP-seq
MIRT1515469	hsa-miR-30e	CLIP-seq
MIRT2155576	hsa-miR-3136-5p	CLIP-seq
MIRT1515472	hsa-miR-3158-5p	CLIP-seq
MIRT1515473	hsa-miR-3160-3p	CLIP-seq
MIRT1515475	hsa-miR-3182	CLIP-seq
MIRT1515476	hsa-miR-323-3p	CLIP-seq
MIRT1515477	hsa-miR-323b-3p	CLIP-seq
MIRT1515478	hsa-miR-330-3p	CLIP-seq
MIRT2155577	hsa-miR-331-3p	CLIP-seq
MIRT2155578	hsa-miR-337-5p	CLIP-seq
MIRT2155579	hsa-miR-342-5p	CLIP-seq
MIRT1515480	hsa-miR-3607-3p	CLIP-seq
MIRT1515482	hsa-miR-3686	CLIP-seq
MIRT2155580	hsa-miR-3913-3p	CLIP-seq
MIRT2155581	hsa-miR-3914	CLIP-seq
MIRT1515448	hsa-miR-3921	CLIP-seq
MIRT1515449	hsa-miR-3977	CLIP-seq
MIRT1515450	hsa-miR-4256	CLIP-seq
MIRT1515487	hsa-miR-4283	CLIP-seq
MIRT2155582	hsa-miR-4290	CLIP-seq
MIRT2155583	hsa-miR-4292	CLIP-seq
MIRT2155584	hsa-miR-433	CLIP-seq
MIRT2155585	hsa-miR-4439	CLIP-seq
MIRT1515491	hsa-miR-4481	CLIP-seq
MIRT2155586	hsa-miR-4483	CLIP-seq
MIRT1515492	hsa-miR-4487	CLIP-seq
MIRT2155587	hsa-miR-4513	CLIP-seq
MIRT2155588	hsa-miR-4651	CLIP-seq
MIRT1515451	hsa-miR-4653-5p	CLIP-seq
MIRT2155589	hsa-miR-4664-5p	CLIP-seq
MIRT1515495	hsa-miR-4699-3p	CLIP-seq
MIRT1515496	hsa-miR-4701-3p	CLIP-seq
MIRT1515497	hsa-miR-4705	CLIP-seq
MIRT2155590	hsa-miR-4713-5p	CLIP-seq
MIRT1515499	hsa-miR-4717-3p	CLIP-seq
MIRT1515500	hsa-miR-4719	CLIP-seq
MIRT1515501	hsa-miR-4731-5p	CLIP-seq
MIRT2155591	hsa-miR-4733-5p	CLIP-seq
MIRT1515502	hsa-miR-4745-5p	CLIP-seq
MIRT2155592	hsa-miR-4751	CLIP-seq
MIRT1515503	hsa-miR-4753-3p	CLIP-seq
MIRT1515505	hsa-miR-4758-5p	CLIP-seq
MIRT2155593	hsa-miR-4766-5p	CLIP-seq
MIRT1515506	hsa-miR-4768-5p	CLIP-seq
MIRT2155594	hsa-miR-488	CLIP-seq
MIRT2155595	hsa-miR-489	CLIP-seq
MIRT1515509	hsa-miR-496	CLIP-seq
MIRT1515452	hsa-miR-502-5p	CLIP-seq
MIRT1515510	hsa-miR-515-5p	CLIP-seq
MIRT1515453	hsa-miR-516a-3p	CLIP-seq
MIRT2155596	hsa-miR-532-3p	CLIP-seq
MIRT1515511	hsa-miR-543	CLIP-seq
MIRT2155597	hsa-miR-553	CLIP-seq
MIRT1515512	hsa-miR-558	CLIP-seq
MIRT1515515	hsa-miR-591	CLIP-seq
MIRT2155598	hsa-miR-608	CLIP-seq
MIRT1515518	hsa-miR-622	CLIP-seq
MIRT1515454	hsa-miR-627	CLIP-seq
MIRT2155599	hsa-miR-629	CLIP-seq
MIRT2155600	hsa-miR-759	CLIP-seq
MIRT1515455	hsa-miR-1184	CLIP-seq
MIRT1515456	hsa-miR-1205	CLIP-seq
MIRT2155570	hsa-miR-1224-5p	CLIP-seq
MIRT2155571	hsa-miR-1249	CLIP-seq
MIRT2155572	hsa-miR-1255a	CLIP-seq
MIRT2155573	hsa-miR-1255b	CLIP-seq
MIRT1515458	hsa-miR-1262	CLIP-seq
MIRT1515459	hsa-miR-129-5p	CLIP-seq
MIRT1515460	hsa-miR-132	CLIP-seq
MIRT2375240	hsa-miR-1324	CLIP-seq
MIRT2375241	hsa-miR-15a	CLIP-seq
MIRT2375242	hsa-miR-15b	CLIP-seq
MIRT2375243	hsa-miR-16	CLIP-seq
MIRT2375244	hsa-miR-195	CLIP-seq
MIRT1515462	hsa-miR-204	CLIP-seq
MIRT1515463	hsa-miR-211	CLIP-seq
MIRT1515464	hsa-miR-212	CLIP-seq
MIRT1515470	hsa-miR-3147	CLIP-seq
MIRT1515472	hsa-miR-3158-5p	CLIP-seq
MIRT1515474	hsa-miR-3170	CLIP-seq
MIRT1515476	hsa-miR-323-3p	CLIP-seq
MIRT1515478	hsa-miR-330-3p	CLIP-seq
MIRT2155577	hsa-miR-331-3p	CLIP-seq
MIRT1515479	hsa-miR-3545-5p	CLIP-seq
MIRT2375245	hsa-miR-371-5p	CLIP-seq
MIRT2375246	hsa-miR-3909	CLIP-seq
MIRT2155580	hsa-miR-3913-3p	CLIP-seq
MIRT2155581	hsa-miR-3914	CLIP-seq
MIRT1515449	hsa-miR-3977	CLIP-seq
MIRT2375247	hsa-miR-424	CLIP-seq
MIRT1515484	hsa-miR-4266	CLIP-seq
MIRT1515485	hsa-miR-4280	CLIP-seq
MIRT1515486	hsa-miR-4281	CLIP-seq
MIRT2155582	hsa-miR-4290	CLIP-seq
MIRT2155583	hsa-miR-4292	CLIP-seq
MIRT1515488	hsa-miR-4425	CLIP-seq
MIRT2375248	hsa-miR-4438	CLIP-seq
MIRT1515489	hsa-miR-4446-5p	CLIP-seq
MIRT1515490	hsa-miR-4455	CLIP-seq
MIRT2375249	hsa-miR-4504	CLIP-seq
MIRT2375250	hsa-miR-4520a-5p	CLIP-seq
MIRT2375251	hsa-miR-4520b-5p	CLIP-seq
MIRT2375252	hsa-miR-4524	CLIP-seq
MIRT1515495	hsa-miR-4699-3p	CLIP-seq
MIRT1515496	hsa-miR-4701-3p	CLIP-seq
MIRT1515498	hsa-miR-4707-5p	CLIP-seq
MIRT1515500	hsa-miR-4719	CLIP-seq
MIRT1515501	hsa-miR-4731-5p	CLIP-seq
MIRT2155591	hsa-miR-4733-5p	CLIP-seq
MIRT2155592	hsa-miR-4751	CLIP-seq
MIRT1515503	hsa-miR-4753-3p	CLIP-seq
MIRT1515504	hsa-miR-4755-5p	CLIP-seq
MIRT1515506	hsa-miR-4768-5p	CLIP-seq
MIRT1515507	hsa-miR-4796-3p	CLIP-seq
MIRT1515508	hsa-miR-486-5p	CLIP-seq
MIRT2155595	hsa-miR-489	CLIP-seq
MIRT1515509	hsa-miR-496	CLIP-seq
MIRT2375253	hsa-miR-497	CLIP-seq
MIRT2375254	hsa-miR-503	CLIP-seq
MIRT2375255	hsa-miR-542-3p	CLIP-seq
MIRT1515511	hsa-miR-543	CLIP-seq
MIRT2155597	hsa-miR-553	CLIP-seq
MIRT1515517	hsa-miR-609	CLIP-seq
MIRT1515518	hsa-miR-622	CLIP-seq
MIRT1515519	hsa-miR-623	CLIP-seq
MIRT2375256	hsa-miR-646	CLIP-seq
MIRT1515520	hsa-miR-651	CLIP-seq
MIRT2375257	hsa-miR-888	CLIP-seq
MIRT2155571	hsa-miR-1249	CLIP-seq
MIRT2155577	hsa-miR-331-3p	CLIP-seq
MIRT2155582	hsa-miR-4290	CLIP-seq
MIRT2155583	hsa-miR-4292	CLIP-seq
MIRT2375248	hsa-miR-4438	CLIP-seq
MIRT2155597	hsa-miR-553	CLIP-seq
MIRT2155570	hsa-miR-1224-5p	CLIP-seq
MIRT2155571	hsa-miR-1249	CLIP-seq
MIRT2155572	hsa-miR-1255a	CLIP-seq
MIRT2155573	hsa-miR-1255b	CLIP-seq
MIRT1515459	hsa-miR-129-5p	CLIP-seq
MIRT1515461	hsa-miR-188-5p	CLIP-seq
MIRT1515447	hsa-miR-2115	CLIP-seq
MIRT1515470	hsa-miR-3147	CLIP-seq
MIRT2667829	hsa-miR-3160-5p	CLIP-seq
MIRT1515474	hsa-miR-3170	CLIP-seq
MIRT2667830	hsa-miR-3200-3p	CLIP-seq
MIRT1515477	hsa-miR-323b-3p	CLIP-seq
MIRT1515478	hsa-miR-330-3p	CLIP-seq
MIRT2155577	hsa-miR-331-3p	CLIP-seq
MIRT1515479	hsa-miR-3545-5p	CLIP-seq
MIRT1515481	hsa-miR-3659	CLIP-seq
MIRT2667831	hsa-miR-369-3p	CLIP-seq
MIRT2375246	hsa-miR-3909	CLIP-seq
MIRT2155581	hsa-miR-3914	CLIP-seq
MIRT1515448	hsa-miR-3921	CLIP-seq
MIRT1515449	hsa-miR-3977	CLIP-seq
MIRT1515450	hsa-miR-4256	CLIP-seq
MIRT1515486	hsa-miR-4281	CLIP-seq
MIRT2155582	hsa-miR-4290	CLIP-seq
MIRT2155583	hsa-miR-4292	CLIP-seq
MIRT1515488	hsa-miR-4425	CLIP-seq
MIRT2375248	hsa-miR-4438	CLIP-seq
MIRT2375250	hsa-miR-4520a-5p	CLIP-seq
MIRT2375251	hsa-miR-4520b-5p	CLIP-seq
MIRT1515451	hsa-miR-4653-5p	CLIP-seq
MIRT1515494	hsa-miR-4658	CLIP-seq
MIRT1515498	hsa-miR-4707-5p	CLIP-seq
MIRT2155592	hsa-miR-4751	CLIP-seq
MIRT1515506	hsa-miR-4768-5p	CLIP-seq
MIRT1515507	hsa-miR-4796-3p	CLIP-seq
MIRT1515509	hsa-miR-496	CLIP-seq
MIRT1515452	hsa-miR-502-5p	CLIP-seq
MIRT1515510	hsa-miR-515-5p	CLIP-seq
MIRT1515453	hsa-miR-516a-3p	CLIP-seq
MIRT1515511	hsa-miR-543	CLIP-seq
MIRT2667832	hsa-miR-548ac	CLIP-seq
MIRT2667833	hsa-miR-548ae	CLIP-seq
MIRT2667834	hsa-miR-548aj	CLIP-seq
MIRT2667835	hsa-miR-548am	CLIP-seq
MIRT2667836	hsa-miR-548d-3p	CLIP-seq
MIRT2667837	hsa-miR-548x	CLIP-seq
MIRT2667838	hsa-miR-548z	CLIP-seq
MIRT2155597	hsa-miR-553	CLIP-seq
MIRT1515514	hsa-miR-574-5p	CLIP-seq
MIRT1515515	hsa-miR-591	CLIP-seq
MIRT1515516	hsa-miR-595	CLIP-seq
MIRT1515454	hsa-miR-627	CLIP-seq
MIRT2155570	hsa-miR-1224-5p	CLIP-seq
MIRT2155571	hsa-miR-1249	CLIP-seq
MIRT2155572	hsa-miR-1255a	CLIP-seq
MIRT2155573	hsa-miR-1255b	CLIP-seq
MIRT1515459	hsa-miR-129-5p	CLIP-seq
MIRT1515461	hsa-miR-188-5p	CLIP-seq
MIRT1515447	hsa-miR-2115	CLIP-seq
MIRT1515470	hsa-miR-3147	CLIP-seq
MIRT2667829	hsa-miR-3160-5p	CLIP-seq
MIRT1515474	hsa-miR-3170	CLIP-seq
MIRT2667830	hsa-miR-3200-3p	CLIP-seq
MIRT1515477	hsa-miR-323b-3p	CLIP-seq
MIRT2155577	hsa-miR-331-3p	CLIP-seq
MIRT1515479	hsa-miR-3545-5p	CLIP-seq
MIRT2667831	hsa-miR-369-3p	CLIP-seq
MIRT2375246	hsa-miR-3909	CLIP-seq
MIRT1515448	hsa-miR-3921	CLIP-seq
MIRT1515449	hsa-miR-3977	CLIP-seq
MIRT1515486	hsa-miR-4281	CLIP-seq
MIRT2155582	hsa-miR-4290	CLIP-seq
MIRT2155583	hsa-miR-4292	CLIP-seq
MIRT1515488	hsa-miR-4425	CLIP-seq
MIRT2375248	hsa-miR-4438	CLIP-seq
MIRT2375250	hsa-miR-4520a-5p	CLIP-seq
MIRT2375251	hsa-miR-4520b-5p	CLIP-seq
MIRT1515451	hsa-miR-4653-5p	CLIP-seq
MIRT1515498	hsa-miR-4707-5p	CLIP-seq
MIRT2155592	hsa-miR-4751	CLIP-seq
MIRT1515506	hsa-miR-4768-5p	CLIP-seq
MIRT1515507	hsa-miR-4796-3p	CLIP-seq
MIRT1515509	hsa-miR-496	CLIP-seq
MIRT1515452	hsa-miR-502-5p	CLIP-seq
MIRT1515510	hsa-miR-515-5p	CLIP-seq
MIRT1515453	hsa-miR-516a-3p	CLIP-seq
MIRT1515511	hsa-miR-543	CLIP-seq
MIRT2667832	hsa-miR-548ac	CLIP-seq
MIRT2667833	hsa-miR-548ae	CLIP-seq
MIRT2667834	hsa-miR-548aj	CLIP-seq
MIRT2667835	hsa-miR-548am	CLIP-seq
MIRT2667836	hsa-miR-548d-3p	CLIP-seq
MIRT2667837	hsa-miR-548x	CLIP-seq
MIRT2667838	hsa-miR-548z	CLIP-seq
MIRT2155597	hsa-miR-553	CLIP-seq
MIRT1515515	hsa-miR-591	CLIP-seq
MIRT1515454	hsa-miR-627	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IMP	25593309
GO:0000724	Process	Double-strand break repair via homologous recombination	IMP	25593309
GO:0000785	Component	Chromatin	IDA	25593309, 26655721, 27732854, 30134174, 36064715
GO:0003714	Function	Transcription corepressor activity	IBA
GO:0003714	Function	Transcription corepressor activity	IMP	27477906, 33323928
GO:0003714	Function	Transcription corepressor activity	ISS
GO:0005515	Function	Protein binding	IPI	15095401, 16147992, 27732854, 28966017, 30134174, 32296183, 35916866, 36950384
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	27477906, 27732854, 28966017
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	IMP	28966017
GO:0006325	Process	Chromatin organization	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0007399	Process	Nervous system development	IMP	35916866
GO:0008270	Function	Zinc ion binding	IDA	28966017
GO:0008270	Function	Zinc ion binding	IEA
GO:0019904	Function	Protein domain specific binding	IDA	28966017
GO:0030336	Process	Negative regulation of cell migration	IMP	27477906
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	IMP	26655721
GO:0032968	Process	Positive regulation of transcription elongation by RNA polymerase II	IPI	30134174
GO:0043197	Component	Dendritic spine	IEA
GO:0043198	Component	Dendritic shaft	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051491	Process	Positive regulation of filopodium assembly	IEA
GO:0060999	Process	Positive regulation of dendritic spine development	IEA
GO:0071168	Process	Protein localization to chromatin	IMP	25593309
GO:0090734	Component	Site of DNA damage	IDA	25593309
GO:0098815	Process	Modulation of excitatory postsynaptic potential	IEA
GO:0140015	Function	Histone H3K14ac reader activity	IDA	27477906
GO:0140109	Function	Histone H3K4me1 reader activity	IDA	27477906
GO:0140297	Function	DNA-binding transcription factor binding	ISS
GO:1902897	Process	Regulation of postsynaptic density protein 95 clustering	IEA
GO:1902952	Process	Positive regulation of dendritic spine maintenance	IEA

MIM	HGNC	e!Ensembl
615713	9397	ENSG00000101040

Q9ULU4

Protein name

MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-contai

Protein function

Chromatin reader that recognizes dual histone modifications such as histone H3.1 dimethylated at 'Lys-36' and histone H4 acetylated at 'Lys-16' (H3.1K36me2-H4K16ac) and histone H3 methylated at 'Lys-4' and histone H4 acetylated at 'Lys-14' (H3K4

PDB

4COS , 5B73 , 5MQ4 , 5Y1Z , 7CWH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00439	Bromodomain	157 → 240	Bromodomain	Domain
PF00855	PWWP	275 → 351	PWWP domain	Domain
PF12064	DUF3544	413 → 620	Protein kinase C-binding protein 1	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in neurons (at protein level) (PubMed:36064715). Absent in astrocytes (at protein level) (PubMed:36064715). Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta (PubMed:11003709, Pu

Sequence

MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSE
LRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSE
PEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLE
QHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKV
VIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKD
GQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVF
NYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGT
GRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTK
TGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQS
TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDS
EYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADP
GAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGED
HSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTS
TSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKMQRQ
QQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPSTSTITLVTSTQSSPLVTSSG
SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEI
RRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVD
ETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTE
TLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQG
SDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD

Sequence length

1186

Interactions

View interactions

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Neurodevelopmental disorder	Pathogenic	rs776813452	RCV003592053

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Intellectual disability	Uncertain significance	rs1135401783	RCV000496152
See cases	Uncertain significance	rs2147190350	RCV002252836
ZMYND8-associated neurodevelopmental disorder	Uncertain significance	rs776813452	RCV003885426
ZMYND8-related disorder	Uncertain significance; Likely benign	rs757483496, rs373180222, rs1406141169, rs776813452, rs144592314	RCV003406258 RCV003422421 RCV003397525 RCV004755029 RCV003959003

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Associate	28055972, 30952871, 33593912
Carcinoma Renal Cell	Stimulate	33593912
Colorectal Neoplasms	Associate	32224527
Disease	Associate	36153585
Endometriosis	Associate	36153585
Glioblastoma	Associate	32832624
Glioma	Associate	36692427, 36826993
Leukemia	Associate	34358447
Leukemia Myeloid Acute	Associate	23667654, 34358447, 34478652
Neoplasms	Associate	29393731, 30952871, 32224527, 32832624, 33593912, 36153585
Triple Negative Breast Neoplasms	Associate	30854423

ZMYND8 (zinc finger MYND-type containing 8)