CORO1C (coronin 1C)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23603 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Coronin 1C |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CORO1C |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HCRNN4 |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q24.11 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein com |
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miRNA
miRNA information provided by mirtarbase database.
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| Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q9ULV4 | ||||||||||||||||||||||||||||||
| Protein name | Coronin-1C (Coronin-3) (hCRNN4) | ||||||||||||||||||||||||||||||
| Protein function | Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed:25074804, PubMed:25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed:25074804, PubMed:25 | ||||||||||||||||||||||||||||||
| PDB | 7STY | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10828594}. | ||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 474 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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