ARL2BP (ARF like GTPase 2 binding protein)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23568 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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ARF like GTPase 2 binding protein |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ARL2BP |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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BART, BART1, RP66, RP82 |
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Chromosome
Chromosome number
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16 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16q13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, o |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9Y2Y0 | ||||||||||
| Protein name | ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1) | ||||||||||
| Protein function | Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. | ||||||||||
| PDB | 2K9A , 3DOE , 3DOF | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in retina pigment epithelial cells (at protein level). Widely expressed. {ECO:0000269|PubMed:10488091, ECO:0000269|PubMed:23849777}. | ||||||||||
| Sequence |
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| Sequence length | 163 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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