ZNF346 (zinc finger protein 346)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23567 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Zinc finger protein 346 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ZNF346 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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JAZ, Zfp346 |
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Chromosome
Chromosome number
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5 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q35.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q9UL40 | |||||||||||||||||||||||||
| Protein name | Zinc finger protein 346 (Just another zinc finger protein) | |||||||||||||||||||||||||
| Protein function | Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053). May bind to specific miRNA hairpins (PubMed:28431233). {ECO:0000269|PubMed:24521053, ECO:0000269|PubMed:28431 | |||||||||||||||||||||||||
| PDB | 2MKD , 2MKN | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 294 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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