Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
23560
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
GTP binding protein 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
GTPBP4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
CRFG, NGB, NOG1 |
Chromosome
Chromosome number
|
10 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
10p15.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. `Active` in this context usually means that the molecule acts as a signal to trigger other ev |
UniProt ID |
Q9BZE4
|
Protein name |
GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1) |
Protein function |
Involved in the biogenesis of the 60S ribosomal subunit (PubMed:32669547). Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest (PubMed:20308539). |
PDB |
6LSS
,
6LU8
,
8FKP
,
8FKQ
,
8FKR
,
8FKS
,
8FKT
,
8FKU
,
8FKV
,
8FKW
,
8FKX
,
8FKY
,
8FKZ
,
8FL0
,
8FL2
,
8FL3
,
8FL4
,
8FL6
,
8FL7
,
8FL9
,
8FLA
,
8FLB
,
8FLC
,
8FLD
,
8FLE
,
8FLF
,
8IDT
,
8IDY
,
8IE3
,
8INE
,
8INF
,
8INK
,
8IPD
,
8IPX
,
8IPY
,
8IR1
,
8IR3
,
8RL2
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF17835
|
NOG1_N |
6 → 165 |
NOG1 N-terminal helical domain |
Domain |
PF06858
|
NOG1 |
235 → 292 |
Nucleolar GTP-binding protein 1 (NOG1) |
Family |
PF08155
|
NOGCT |
395 → 446 |
NOGCT (NUC087) domain |
Domain |
|
Sequence |
|
Sequence length |
634 |
Interactions |
View interactions
|