NCS1 (neuronal calcium sensor 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23413 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Neuronal calcium sensor 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NCS1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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FLUP, FREQ |
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Chromosome
Chromosome number
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9 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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9q34.11 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | P62166 | ||||||||||||||||||||
| Protein name | Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein) | ||||||||||||||||||||
| Protein function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity | ||||||||||||||||||||
| PDB | 1G8I , 2LCP , 4GUK , 5O9S , 6QI4 , 8AHY , 8ALH , 8ALM | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 190 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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