NCS1 (neuronal calcium sensor 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23413 |
| Gene name | Neuronal calcium sensor 1 |
| Gene symbol | NCS1 |
| Synonyms (NCBI Gene) |
FLUPFREQ
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| Chromosome | 9 |
| Chromosome location | 9q34.11 |
| Summary | This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner |
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miRNA
miRNA information provided by mirtarbase database.
523
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P62166 | ||||||||||||||||||||
| Protein name | Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein) | ||||||||||||||||||||
| Protein function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity | ||||||||||||||||||||
| PDB | 1G8I , 2LCP , 4GUK , 5O9S , 6QI4 , 8AHY , 8ALH , 8ALM | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 190 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
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